Prevenar 13 yog ib qho kev npaj muaj polysaccharides ntawm cov kab mob pathogenic Streptococcus pneumoniae. Siv pneumococcal conjugates, kev txhaj tshuaj tiv thaiv tib neeg niaj hnub ua los txhawm rau tiv thaiv kev raug mob ntawm kev tiv thaiv thiab mob hauv txoj hlab pa. Cov tshuaj yog qhov tsim nyog rau kev tsim cov tshuaj tiv thaiv nyob rau hauv kev txhaj tshuaj tiv thaiv kab mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Tsis yog.
Prevenar 13 yog ib qho kev npaj muaj polysaccharides ntawm cov kab mob pathogenic Streptococcus pneumoniae.
ATX
J07AL02.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm ib qho kev ncua rau lub qhov tso rau hauv cov leeg txheej. 1 pawg ntawm cov tshuaj uas muaj ntim ntawm 0.5 ml muaj cov kab mob pneumococcal conjugates ntawm cov serotypes hauv qab no yog cov tshuaj txuam:
- 1;
- 2;
- 3;
- 4;
- 6 A, B;
- 7F;
- 9V;
- 14;
- 19 A, F;
- 23F.
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm ib qho kev ncua rau lub qhov tso rau hauv cov leeg txheej.
Cov tshuaj sib xyaw ua ke ntawm cov tshuaj tseem suav nrog oligosaccharide hom 18C thiab kabmob qaij protein muaj CRM-197. Nrog rau tom kawg, pneumococcal polysaccharides tsim ib txoj. Cov khoom xyaw ntxiv suav nrog aluminium phosphate thiab sodium chloride. Pom, qhov kev muab tshem tawm yog qhov dawb homogeneous.
Ciaj los tsis paub
Cov tshuaj tiv thaiv tsis muaj sia. Rau nws txoj kev txhim kho, cov kab mob tsis muaj zog lossis tuag ntawm cov kab mob pathogenic tsis tau siv.
Pharmacological kev txiav txim
Nrog kev qhia txog cov tshuaj tiv thaiv mus rau hauv lub cev, kev ua haujlwm ntau ntxiv ntawm cov tshuaj tiv thaiv kom ua rau cov tshuaj tiv thaiv kab mob sib txuas ntawm cov kab mob pathogenic ntawm Streptococcus pneumoniae pib. Cov tshuaj tiv thaiv kab mob tso cai rau koj los tsim cov tshuaj tiv thaiv kab mob tsim nyog thiab ua kom lub cev muaj zog tiv thaiv mus rau lub sijhawm xav ua kom muaj kab mob phem ntxiv. Txhaj tshuaj tiv thaiv tso cai koj los npaj lub cev rau kev yeej ntawm txhua qhov kev xav ntawm pneumococcal polysaccharide.
Hauv qab ntawm lymphocytes, cov kab mob polysaccharides zom rau hauv cov khoom lag luam metabolic.
Cov Tshuaj Pharmacokinetics
Thaum polysaccharides ntawm cov kab mob Streptococcus pneumoniae leeg nkag rau cov hlab ntshav, cov neeg pabcuam T-tau lees paub, uas pib zais cytokines los qhib T-killers, B-lymphocytes thiab monocytes. Hauv qab ntawm lymphocytes, cov kab mob polysaccharides zom rau hauv cov khoom lag luam metabolic. Lub tom kawg tsis yog qhov zoo rau kev tshawb nrhiav, vim tias lawv zoo sib xws rau cov khoom tsim hauv lub cev. Yog li, cov pharmacokinetic tsis ntawm metabolites tsis tau txiav txim siab.
Qhov tshuaj tiv thaiv yog dab tsi?
Txhaj tshuaj tiv thaiv yog nqa tawm raws li cov xwm txheej hauv qab no:
- lub sijhawm teem sijhawm raws li daim ntawv teev sijhawm hauv lub tebchaws rau kev tiv thaiv kev kis kabmob uas tsis kis tus kabmob (mob pobntseg hauv nruab nrab, mob ntsws hauv zejzos) thiab tus kabmob (kab mob ua paug rau lub cev, mob ntsws muaj dej hauv cov ntshav, sepsis, mob ntsws hnyav) xwm txheej;
- raws li kev tiv thaiv kab mob rau cov neeg uas muaj kev tiv thaiv kab mob uas muaj kev pheej hmoo kis mob hnyav.
Cov tom kawg suav nrog cov neeg mob uas muaj kab mob yug los ntawm lub nruab zog, cov neeg mob HIV thiab cov neeg tau txais kev kho mob tiv thaiv kab mob. Kev tiv thaiv qis qis tuaj yeem txhim kho tom qab ntawm:
- kab mob ntev ntawm kev ua pa ntawm lub cev thiab cov hlab plawv;
- lub xub ntiag ntawm cochlear cog;
- kev kho mob cancer;
- bronchial hawb pob;
- qhov mob txhab ntawm tubercle bacillus;
- hnub nyoog siab heev;
- cwj pwm tsis zoo.
Txhaj tshuaj tiv thaiv yog qhov tsim nyog rau cov menyuam yug ua ntej thiab cov neeg hauv pawg nrog pawg coob.
Cov Yuav Tsum Muaj
Kev txhaj tshuaj tiv thaiv yog contraindicated nyob rau hauv cov neeg mob uas tshaj tawm cov lus pov tseg ntawm cov ntaub so ntswg mus rau tus kab mob diphtheria cov protein, cov khoom siv ntu ntawm Prevenar 13. Nws raug txwv tsis pub txhaj tshuaj rau cov neeg uas tau tsim muaj kev phiv tshuaj rau cov koob tshuaj yav dhau los.
Ncua kev txhaj tshuaj tsis raug pom zoo rau kev kis mob hnyav, mob ntev ntawm mob theem lossis kis mob. Kev txhaj tshuaj tiv thaiv yog nqa tawm tom qab ib tus neeg tau zoo tu qab tso.
Thaum twg thiab li cas txhaj tshuaj tiv thaiv
Intramuscular txhaj ntawm Prevenar 13 yog qhov tsim nyog los tsim kev tiv thaiv kev tiv thaiv kabmob raws li ceeb toom ntawm cov xwm txheej hauv qab no:
- mob ntsws;
- cov txheej txheem mob nyob rau hauv cov pa hauv nruab nrog sab saud: sinusitis, mob hlab ntshav, mob tonsillitis;
- mob rau daim npluag qhwv
- otitis media;
- cov kab mob ntsws.
Cov tshuaj yaj yeeb pab ua rau txo qis kev pheej hmoo ntawm cov teeb meem tom qab yeej ntawm catarrhal kab mob ntawm kev kis mob. Tshwj xeeb feem ntau cov me nyuam muaj hnub nyoog qis dua 5 xyoos thiab cov neeg tsis muaj zog tiv thaiv kab mob. Txhaj tshuaj tiv thaiv yog ua tiav raws li tau npaj tseg.
Pes tsawg zaus
Tus naj npawb ntawm kev txhaj tshuaj nyob ntawm lub hnub nyoog ntawm tus neeg mob. Qhov nruab nrab, txhaj tshuaj tiv thaiv pib rau menyuam yaus txij li 2 txog 6 hlis. Cov tshuaj tau muab tshuaj nyob rau hauv 4 qib raws li tau tsim lub sijhawm thiab lub sijhawm ntawm kev txhaj tshuaj:
- Thawj 3 koob txhaj nrog xa nrog lub sijhawm ntawm kev tswj hwm ntawm 30 hnub.
- 4 zaug txhaj tshuaj tiv thaiv thaum nce mus txog lub hnub nyoog 15 lub hlis.
Yog tias kev kho tshuaj pib txij li ncua sij hawm 7 txog 11 hlis, thawj 2 koob tshuaj tiv thaiv yog muab nrog lub sijhawm 1 lub hlis. Kev txhaj tshuaj zaum kawg tau muab tso rau thaum muaj hnub nyoog 2 xyoos. Hauv qhov no, kev txhaj tshuaj tiv thaiv tsuas yog ua 3 qib xwb.
Yog tias kev qhia txog kev txhaj tshuaj tiv thaiv yog ua tiav thaum 1 lossis 2 xyoos ntawm lub neej, tom qab ntawd muab 2 qhov hno nrog ib ncua ntxiv ntawm kev txhaj tshuaj ntawm 2 hlis.
Yog tias kev qhia txog kev txhaj tshuaj tiv thaiv yog ua tiav thaum 1 lossis 2 xyoos ntawm lub neej, tom qab ntawd muab 2 qhov hno nrog ib ncua ntxiv ntawm kev txhaj tshuaj ntawm 2 hlis. Cov neeg mob laus dua 18 xyoo Prevenar tau txais koob tshuaj ib zaug.
Yuav zam txim li cas
Ua kom muaj zog hauv lub cev tiv thaiv kab mob tej zaum yuav nrog ua npaws thiab tsis muaj zog. Yog tias qhov kub tau hla tus ciam teb ntawm + 38 ° C thiab muaj qhov ntswg txhaws ntswg, koj yuav tsum nrhiav kev pab kho mob.
Puas yog nws tuaj yeem taug kev tom qab txhaj tshuaj tiv thaiv
Hauv ib lub hlis tom qab kev siv tshuaj, nws raug nquahu kom tsis txhob taug kev hauv qhov chaw muaj neeg coob coob, vim tias kev pheej hmoo kis mob los ntawm kev sib chwv nrog cov neeg nqa khoom ntawm tus mob pneumococcal nce ntxiv. Thaum mus ntsib tsev kho mob, looj daim npog qhov ncauj. Hauv lub caij ntuj no, tawm hauv tsev tsis pom zoo. Koj tuaj yeem taug kev tsuas yog hauv huab cua sov. Tom qab txhaj tshuaj tiv thaiv, kawm menyuam yaus raug txwv 30 hnub.
Puas yog nws muaj ntshav qab zib tau
Nrog txoj kev tsis sib luag ntawm kev hloov pauv hauv cov ntshav qab zib cov ntshav siab, lub cev tiv thaiv kab mob tsis muaj zog, yog li cov neeg mob ntshav qab zib yuav tsum tau txhaj tshuaj. Pneumococcal polysaccharides yuav tsis cuam tshuam rau cov ntshav piam thaj hauv ntshav.
Hauv ib lub hlis tom qab kev siv tshuaj, nws raug nquahu kom tsis txhob taug kev hauv qhov chaw muaj neeg coob coob, vim tias kev pheej hmoo kis mob los ntawm kev sib chwv nrog cov neeg nqa khoom ntawm tus mob pneumococcal nce ntxiv.
Txoj kev ntawm daim ntawv thov
Kev txhaj tshuaj yog txhaj rau hauv cov chaw uas muaj qhov sib sib zog nqus ntawm cov leeg pob txha: cov leeg deltoid (cov neeg laus dua 2 xyoos), saum npoo ntawm tus ncej (txog 3 xyoos). Intramuscularly muab 0.5 ml ntawm cov tshuaj hauv ib zaug tshuaj.
Ua ntej siv, koob txhaj tshuaj nrog cov tshuaj yuav tsum txhaws kom tau txais qhov kev ncua sib xws. Cov tshuaj tsis tuaj yeem siv yog tias muaj lub cev txawv teb chaws hauv daim ntawv tshuaj lossis thaum cov xim hloov.
Nws yog txwv tsis pub qhia cov tshuaj mus rau hauv cov hlab ntsha los yog mus rau hauv gluteus maximus.
Cov neeg mob tom qab hloov cov ntshav ntawm hemocytoblasts xav tau ib chav kawm ntawm kev txhaj tshuaj los ntawm 4 koob ntawm cov tshuaj hauv ib zaug tshuaj. Thawj koob txhaj tshuaj yog nqa los ntawm 3 txog 6 hlis tom qab hloov pauv. 2 tom qab txhaj tshuaj yog siv nrog ntu nyob hauv ib hlis. Cov koob tshuaj kawg yog muab tom qab 3 tshuaj tiv thaiv nrog rau ncua sij hawm 6 lub hlis.
Ib tug menyuam yug ua ntej yug yuav tsum txhaj tshuaj tiv thaiv 4 zaug. Kev txhaj thawj zaug yog muab thaum 3 hlis tom qab yug, 2 lub sijhawm txuas ntxiv yog nqa nrog ib tus menyuam dhau 1 hlis. 4 koob tshuaj yog muab rau hauv 12-15 lub hlis.
Sab sij huam
Ntawm qhov chaw txhaj tshuaj, kev txhim kho kev o tuaj yeem ua tiav, daim tawv nqaij ua kom nruj thiab xim liab. Hauv cov menyuam yaus, lub cev kub nce.
Kev kho mob txoj hnyuv
Cov kev xav tsis zoo hauv lub plab zom mov tau tshwm sim hauv daim ntawv zawv plab, ntuav tsis txaus, thiab ua kom qab los. Hauv qee qhov tshwj xeeb, muaj kev pheej hmoo ntawm hyperbilirubinemia, jaundice, thiab mob ntawm daim siab.
Hauv thaum yau, tom qab siv cov tshuaj, lub cev kub nce.
Hematopoietic plab hnyuv siab raum
Cov teeb meem tsawg, muaj kev nce hauv cov qog ntshav, nce ntxiv hauv qib ntawm leukocytes thiab T-lymphocytes.
Nruab nrab hauv lub paj hlwb
Hauv cov menyuam yaus, thawj xyoo ntawm lub neej yuav pib ua kev txhoj puab heev. Tus me nyuam quaj quaj, tig los ua neeg. Feem ntau cov tib neeg tau mob taub hau, uas ua rau muaj kev cia siab ntawm cov leeg poob siab, tom qab ntawd ua kev txob taus thiab pw tsaug zog. Muaj kev pheej hmoo ntawm cov leeg mob.
Los ntawm lub tshuab ua pa
Tawm tsam keeb kwm ntawm kev cuam tshuam ntawm kev tiv thaiv tsis muaj zog, dyspnea thiab bronchospasm tuaj yeem tsim kho. Hauv cov menyuam yaus, kev hnoos yuav pib, txhaus ntswg yuav tshwm sim.
Los ntawm genitourinary system
Hauv kev sib txuas nrog kev ncua sij hawm hauv kev tso zis thiab cuam tshuam hauv dej-ntsev tshuav, edema uas ua rau nws tus kheej tuaj yeem txhim kho.
Los ntawm cov hlab plawv system
Muaj qee zaus, lub plawv dhia nce siab.
Tawm tsam keeb kwm ntawm kev cuam tshuam ntawm lub cev tsis muaj zog, dyspnea tuaj yeem txhim kho los ntawm kev siv cov tshuaj no.
Kev ua xua
Thaum muaj kev tiv thaiv kab mob tsis haum, qhov ua xua tuaj yeem tshwm sim, tshwm sim hauv daim ntawv ua pob, khaus thiab liab ntawm daim tawv. Muaj qee zaus, qhov tshwm sim ntawm Quincke edema yog ua tau.
Cov lus qhia tshwj xeeb
Hauv 30 feeb tom qab txhaj tshuaj tiv thaiv, tus neeg mob yuav tsum tau txais kev saib xyuas mob nkeeg nruj. Qhov no yog qhov tsim nyog rau kev pab ceev ceev thaum muaj tshwm sim ntawm kev phiv tshuaj anaphylactoid.
Kev ceev faj yuav tsum tau siv thaum muab cov kev ncua rau cov neeg mob uas los ntshav thiab mob thrombocytopenia.
Cawv tau zoo
Tsis pub dhau 2 hnub ua ntej txhaj tshuaj tiv thaiv thiab tom qab 48 teev tom qab kev saib xyuas yeeb tshuaj, dej cawv thiab cawv muaj npaj tsis tau noj. Kev haus dej cawv ethyl ua rau lub cev tsis muaj zog tiv thaiv kab mob thiab txwv tsis pub cov pob txha ntshav hematopoiesis, uas tuaj yeem cuam tshuam tsis zoo rau cov tshuaj tiv thaiv kab mob.
Tsis pub dhau 2 hnub ua ntej txhaj tshuaj tiv thaiv thiab tom qab 48 teev tom qab kev saib xyuas yeeb tshuaj, dej cawv thiab cawv muaj npaj tsis tau noj.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Kev txhaj tshuaj tiv thaiv tsis cuam tshuam ncaj qha rau kev ua haujlwm ntawm lub hauv nruab nrab thiab qhov nqaj ntawm lub paj hlwb. Nws yog ib qho tseem ceeb kom nco ntsoov txog qhov tshwm sim uas yuav tshwm sim los ntawm cov kev mob tshwm sim hauv daim ntawv ntawm mob taub hau thiab qaug dab peg. Vim muaj cov kev pheej hmoo uas twb muaj lawm, yuav tsum tau ceev faj thaum tsav tsheb, tswj cov txheej txheem nyuaj thiab koom nrog lwm cov haujlwm uas yuav tsum muaj kev kub ceev ntawm lub cev thiab lub hlwb kev xav.
Thaum cev xeeb tub thiab lactation
Cov kev tshawb fawb tshaj tawm txog cov nyhuv ntawm cov tshuaj rau cov poj niam cev xeeb tub tsis tau ua, yog li kev txhaj tshuaj tsis pom zoo rau pawg neeg no. Cov lus qhia ntawm Prevenar 13 tuaj yeem tsuas yog nqa tawm hauv lub xeev cov tshuaj tiv thaiv tseem ceeb hauv kev saib xyuas mob nruj nrog kev pom zoo ntawm tus neeg mob.
Thaum txhaj tshuaj tiv thaiv kab mob, nws yog ib qho tsim nyog yuav tsum tsis txhob pub mis niam thiab xa tus me nyuam mus rau cov zaub mov nrog cov mis mos.
Txhaj tshuaj tiv thaiv ntawm cov me nyuam nrog Prevenar 13
Hauv cov menyuam yaus, kev kuaj ntshav hyperthermia. Dr. Komarovsky tau txiav txim siab tias ib txwm 40% ntawm cov neeg mob hauv cov menyuam hnub nyoog qis dua 2 xyoos, qhov kub nce mus rau + 37 ... + 38 ° C, hauv 37% - siab dua 39 ° C. Hauv 30 feeb tom qab kev tswj hwm, tus menyuam yuav tsum nyob hauv kev saib xyuas ntawm tus kws kho mob.
Hnub nyoog laus
Cov neeg laus dua 60 xyoo raug muab tshuaj tiv thaiv kab mob rau cov tshuaj tiv thaiv, cov kab mob sib kis tau yooj yim ntawm txoj hlab pa, nrog rau kev ua rau mob sepsis.
Daim ntawv thov rau lub raum khiav tsis zoo
Kab mob hauv lub raum tsis cuam tshuam rau cov qauv pharmacokinetic thiab kev noj qab haus huv zoo tom qab txhaj tshuaj tiv thaiv kab mob.
Kab mob hauv lub raum tsis cuam tshuam rau cov qauv pharmacokinetic thiab kev noj qab haus huv zoo tom qab txhaj tshuaj tiv thaiv kab mob.
Siv rau lub siab ua haujlwm tsis zoo
Pneumococcal polysaccharides tsis yauv hloov pauv hauv tus kabmob hepatic, yog li ntawd, nrog kev yeej ntawm lub siab, kev tswj hwm ntawm cov tshuaj tau tso cai.
Noj ntau dhau
Tsis muaj ib qho mob ntawm kev noj ntau dhau nrog ib qho kev tswj hwm ntawm qhov siab kawg. Txhaj tshuaj tiv thaiv yog nqa tawm tsuas yog nyob rau hauv chaw haujlwm hauv kev saib xyuas kev kho mob. Nyob rau hauv cov ntaub ntawv ntawm qhov tsis yog koob tshuaj, nws yog theoretically tau nce lossis nce qhov ntxim nyiam ntawm cov kev mob tshwm sim.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj no tuaj yeem siv ua ke nrog lwm cov tshuaj tiv thaiv tsis muaj sia thiab muaj sia nyob, uas suav nrog koob tshuaj tiv thaiv kab mob hauv tebchaws. Hauv qhov no, cov tshuaj tiv thaiv cov mob ntsws uas tsis tuaj yeem sib xyaw nrog lwm txoj hauv kev rau kev tswj hwm hauv niam txiv nyob hauv ib lub taub ntim.
Cov neeg mob uas muaj hnub nyoog tshaj 50 xyoo tso cai muab tshuaj tiv thaiv kev mob ua npaws nrog cov kab mob khaub thuas tsis voos.
Nws yog ib qho tsim nyog los tswj lub xeev ntawm hemostasis hauv kev kho kom zoo nrog anticoagulants.
Nrog saib xyuas
Kev txwv ua ntej ntawm Prevenar 13 nrog kev txhaj tshuaj tiv thaiv mob hnoos qeev-diphtheria-tetanus tau tso cai. Hauv qhov no, nws yog ib qhov tsim nyog los soj qab saib xyuas tus me nyuam. Yog koj xav tias qhov koj tsis xis nyob, sab laj nrog kws kho mob. Nrog kev sib txuam ntawm ntau cov kev txhaj tshuaj, nws yog ib qho tsim nyog yuav tsum tau muab tso rau hauv qhov sib txawv ntawm qhov chaw ntawm lub cev kom txo qis kev pheej hmoo ntawm kev sib xyaw cov tshuaj hauv lub cev.
Nws yog ib qho tsim nyog los tswj lub xeev ntawm hemostasis hauv kev kho kom zoo nrog anticoagulants.
Kev sib xyaw tsis pom zoo
Cov tshuaj yuav tsum tsis txhob siv nrog rau BCG txhaj tshuaj tiv thaiv kab mob ntsws. Cov tshuaj tiv thaiv cov kab mob muaj sia tuaj yeem cuam tshuam qhov tshwm sim lossis txo qhov kev tsim cov tshuaj tiv thaiv tawm tsam kev mob ntsws.
Analogs
Koj tuaj yeem hloov cov tshuaj tiv thaiv nrog cov hauv qab no:
- Mob ntsws 23;
- Pentaxim;
- Sinflorix.
So haujlwm Prevenara 13 los ntawm cov chaw muag tshuaj
Cov tshuaj tiv thaiv tsis raug muag nyob rau ntawm cov chaw muag tshuaj rau cov neeg mob hla khw.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov lus qhia txog kev ncua ntawv yog nqa tawm tsuas yog nyob rau hauv chaw nyob ruaj ruaj nyob rau hauv kev sib txuas nrog qhov kev pheej hmoo ntawm anaphylactic poob siab lossis lwm yam kev tsis zoo. Kev yuav khoom yog nruj me ntsis.
Nqi
Tus nqi nruab nrab ntawm cov tshuaj yog 1877 rubles.
Cia rau cov neeg mob Prevenara 13
Tsis txhob khov cov tshuaj. Qhov kev ncua yog muab tso rau ntawm qhov kub ntawm + 2 ... + 8 ° C nyob rau hauv qhov chaw sib nrug los ntawm lub hnub.
Hnub tas sij hawm
36 hli.
Chaw tsim tshuaj paus
Chav Tuam Tsev Wyeth, USA.
Cov lus qhia txog kev ncua ntawv yog nqa tawm tsuas yog nyob rau hauv chaw nyob ruaj ruaj nyob rau hauv kev sib txuas nrog qhov kev pheej hmoo ntawm anaphylactic poob siab lossis lwm yam kev tsis zoo.
Kev xyuas rau Prevenar 13
Radislav Rusakov, 38 xyoo, Lipetsk
Tus tub feem ntau tau mob khaub thuas, uas nrog mob hawb pob. Tus kws kho mob tau sau ntawv txhawm rau txhaj tshuaj Prevenar 13. Tsis muaj qhov tshwm sim tsis zoo, tab sis tom qab ib lim tiam qhov kub tau nce mus txog 37 ° C. Nyob rau 3 hnub thiab dhau ntawm nws tus kheej. Hauv qhov no, tus me nyuam hnov zoo. Qhov loj tshaj plaws yog cov tshuaj tiv thaiv pab. Tsis pom muaj hawb pob thiab mob khaub thuas. Tus mob ntawm tus me nyuam nyob rau hauv 2 lub lis piam txhim kho, qab los noj mov tshwm, kev tiv thaiv muaj zog. Qhov tshwm sim ntawm kev tiv thaiv kev muaj zog yog ntev, vim hais tias rov qab txhaj tshuaj yog tsim nyog tsuas yog tom qab 5 xyoos.
Zinaida Molchanova, 30 xyoo, Yaroslavl
Tus menyuam tau mob ntau zaus, yog li ntawd lawv tau mus cuag kws kho mob. Cov kws kho mob tshwj xeeb tshaj tawm cov lus qhia ntawm cov tshuaj tiv thaiv Prevenar 13. Tom qab txhaj tshuaj, qhov kub thiab flatulence tau nce ntxiv. Ntawm qhov chaw txhaj tshuaj khaus khaus ntau heev. Tab sis lub caij txias, tus menyuam tsis tau mob txawm tias ib zaug. Nws yog ib qho tseem ceeb kom ua raws li tus kws kho mob cov lus qhia tom qab kev tswj hwm thiab tsis txhob muab tshuaj antipyretic.
