Qhov kev ua tau zoo ntawm Tritace Plus yog ua raws cov teebmeem ntawm ramipril thiab hydrochlorothiazide. Ob qhov sib xyaw tiv thaiv kev hloov pauv ntawm angiotensin I rau hauv daim ntawv ntawm angiotensin II, yog li ua tiav cov nyhuv antihypertensive. Hauv qhov no, cov tshuaj tsis tshua raug kho nyob hauv kev saib mob raws li kev kho mob monotherapy. Cov neeg mob tau txais tus neeg sawv cev hypotensive ua ib feem ntawm txoj kev kho mob ntshav khov kom ua tiav cov ntshav siab.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Hydrochlorothiazide + Ramipril.
ATX
C09BA05.
Qhov kev ua tau zoo ntawm Tritace Plus yog ua raws cov teebmeem ntawm ramipril thiab hydrochlorothiazide.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob hauv daim ntawv foos. 1 ntsiav tshuaj sib txuas 2 lub tebchaw nquag - ramipril thiab hydrochlorothiazide.
| Lub Cheebtsam nquag | Muaj peev xwm sib txuas ua ke, mg | |||
| Ramipril | 12,5 | 12,5 | 25 | 25 |
| Hydrochlorothiazide | 5 | 10 | 5 | 10 |
| Xim tshuaj ntsuab | liab dawb | txiv kab ntxwv | dawb | liab dawb |
Txhawm rau txhawm rau txhim kho cov txheej txheem pharmacokinetic, cov khoom siv ntxiv tau siv:
- sodium stearyl fumarate;
- hlau oxide, uas muab rau cov ntsiav tshuaj ib xim ib tus neeg nyob ntawm kev saib xyuas ntawm cov khoom siv nquag;
- gelatinized pob kws hmoov txhuv nplej siab;
- microcrystalline cellulose;
- hypromellose.
Ntev cov ntsiav tshuaj, nrog faib cov kab ntawm ob sab.
Ib cov tshuaj tsis tshua tau siv tshuaj hauv kev kho mob raws li kev kho mob monotherapy.
Pharmacological kev txiav txim
Tritace sib txuas ua ib qho kev tsis txaus siab ntawm angiotensin hloov mus rau ntawm enzyme (ACE) inhibitor - ramipril, thiab thiazide diuretic hydrochlorothiazide. Kev sib xyaw ua ke ntawm cov khoom siv tseem ceeb muaj qhov ua kom zoo antihypertensive. ACE blocker tiv thaiv kev tsim cov tshuaj angiotensin II, uas yog qhov tsim nyog los txo cov leeg nqaij ntawm cov leeg ntawm cov leeg endothelium.
Ramipril tiv thaiv qhov tshwm sim ntawm vasoconstrictor effect thiab tiv thaiv qhov tawg ntawm bradykinin, ib qho tshuaj rau lub ntuj nthuav dav ntawm cov hlab ntshav. Hydrochlorothiazide ua kom cov vasodilation, vim tias cov hlab ntsha nthuav dav ntxiv. Nws yog ib qho tseem ceeb los tswj lub cev ntim ntawm cov ntshav kom thiaj li zam dhau txoj kev txhim kho ntawm bradycardia thiab arterial hypotension.
Qhov siab tshaj plaws kho tau zoo yog pom 3-6 teev tom qab kev thov thiab mob siab rau ib hnub. Cov nyhuv tshuaj loog ntawm thiazide diuretic rau li 6-12 teev.
Cov Tshuaj Pharmacokinetics
Ramipril thiab hydrochlorothiazide nrawm nrawm rau qhov qis ntawm jejunum, los ntawm qhov chaw uas lawv diffuse mus rau hauv kev cov kab ke. Lub bioavailability ntawm hydrochlorothiazide yog 70%. Hauv cov ntshav, ob qho tshuaj lom neeg cov tshuaj lom kom txog lub siab ntev nyob hauv 2-4 teev. Ramipril muaj qib siab ntawm kev khi rau cov ntshav plasma protein - 73%, thaum tsuas yog 40% ntawm hydrochlorothiazide tsim cov nyom nrog albumin.
Ib nrab-lub neej ntawm ob lub Cheebtsam txog li 5-6 teev. Ramipril yog 60% feem pua hauv cov zis nrog zis. Hydrochlorothiazide tawm lub cev rau hauv nws daim ntawv qub los ntawm 95% los ntawm lub raum hauv 24 teev.
Kev ntsuas rau siv
Cov tshuaj yog xav tau los txo qis ntshav siab.
Cov tshuaj yog xav tau los txo qis ntshav siab.
Cov Yuav Tsum Muaj
Cov tshuaj yog contraindicated nyob rau hauv cov neeg nrog:
- muaj qhov tsis haum rau hydrochlorothiazide, ramipril thiab lwm yam tshuaj muaj ntsis hauv Tritace;
- predisposition rau kev txhim kho Quincke edema;
- mob raum tsis zoo;
- kev hloov pauv hauv cov ntshav electrolytes: potassium, magnesium, calcium;
- daim siab mob siab;
- kev mob ntshav siab los ntshav.
Nrog saib xyuas
Nws yog ib qho tsim nyog los tswj kev saib xyuas kev noj qab haus huv lub sijhawm thaum lub sij hawm kho cov tshuaj yaj yeeb nyob rau hauv cov kev qhia hauv qab no:
- lub plawv dhia tsis zoo;
- kev tsis meej nyob rau hauv sab laug ventricle, tus cwj pwm los ntawm hypertrophic hloov;
- stenosis ntawm lub ntsiab, hlab ntsha hauv hlab ntsha, mob ntshav hlab plawv los yog rau lub raum;
- kev cuam tshuam ntawm cov dej-electrolyte metabolism;
- nrog creatinine tshem tawm ntawm 30-60 ml / min;
- kev rov txhim kho lub sijhawm tom qab lub raum hloov;
- daim siab mob
- kev puas tsuaj rau cov ntaub so ntswg mob sib deev - scleroderma, lupus erythematosus;
- kev tsim txom ntawm cerebral ncig.
Cov neeg mob uas yav dhau los siv tshuaj diuretics yuav tsum tswj hwm lub xeev ntawm cov dej-ntsev sib npaug.
Yuav ua li cas Noj Tritace Plus
Cov tshuaj tsis tau sau tseg yog qhov kev tiv thaiv kabmob ntshav qis. Cov ntsiav tshuaj yog npaj rau kev siv qhov ncauj. Kev noj tshuaj rau yav sawv ntxov yog pom zoo. Kev noj tshuaj yog txiav txim los ntawm tus kws kho mob nyob ntawm qhov ntsuas ntawm ntshav siab (BP) thiab qhov hnyav ntawm kub siab.
Tus txheej txheem koob tshuaj thaum pib ntawm kev kho tshuaj yog 2.5 mg ntawm ramipril hauv kev sib xyaw nrog 12.5 mg ntawm hydrochlorothiazide. Nrog rau kev ua siab zoo, kom ua rau lub siab ntsws hypotensive, ntau npaum yuav ntxiv tom qab 2-3 lub lis piam.
Nrog ntshav qab zib
Cov tshuaj tuaj yeem ua rau cov ntshav qog ntshav qab zib nrog kev siv tshuaj tiv thaiv hypoglycemic los yog cov tshuaj insulin, yog li ntawd, thaum lub sijhawm kho nrog ib qho tshuaj tiv thaiv kab mob, nws yog ib qho tsim nyog yuav tau kho cov tshuaj ntau ntawm cov tshuaj tiv thaiv kab mob. Cov neeg mob ntshav qab zib yuav tsum tau soj ntsuam lawv cov ntshav qab zib kom mus tas li.
Phiv Phim Nyuj Vais Ntxiv
Feem ntau, kev noj tshuaj tsis raug ntawm Tritace ua rau mob nkees thiab mob tob hau.
Kev kho mob txoj hnyuv
Kev kho mob hauv lub plab zom mov yog tshwm sim los ntawm kev loj hlob ntawm cov nqaij mos ntawm cov qog ua kua, qhov tsos ntawm gingivitis, ntuav tsis kam, thiab cem quav. Tej zaum qhov kev txhim kho ntawm txoj hlab plab, tsis xis nyob hauv plab.
Nrog rau cov kab mob plab zom mov, gastritis tuaj yeem txhim kho raws li kev phiv.
Hematopoietic plab hnyuv siab raum
Nrog ib qho kev txo qis ntawm cov hlwb pob txha hematopoiesis, cov naj npawb ntawm cov qe ntshav muaj txig tsawg.
Nruab nrab hauv lub paj hlwb
Nrog rau qhov kev ploj ntawm kev tswj hwm lub siab, tus neeg mob muaj kev nyuaj siab, ntxhov siab, thiab pw tsaug zog. Tawm tsam keeb kwm yav dhau los ntawm kev nyuaj siab ntawm lub paj hlwb, muaj qhov ploj ntawm txoj kev xav hauv qhov chaw, mob taub hau, hnov mob hlawv, poob lossis chim siab.
Los ntawm cov kab mob zis
Tej zaum muaj qhov nce ntawm cov zis tso tawm thiab txoj kev loj hlob ntawm lub raum tsis ua haujlwm.
Los ntawm lub tshuab ua pa
Feem ntau, vim muaj qhov nce ntawm qib bradykinin, qhov hnoos qhuav yuav tshwm sim, hauv qee cov neeg mob - mob ntshav ntswg thiab mob ntawm cov hlab ntshav.
Ntawm ib sab ntawm daim tawv nqaij
Muaj kev pheej hmoo ntawm kev tsim mob angioedema, uas tuaj yeem ua rau asphyxia qee kis. Psoriasis-zoo li cov tsos mob, nce hws, tawm pob, khaus thiab erythema ntawm ntau yam etiologies yog ua tau.
Vim tias tau noj tshuaj, erythema ntawm ntau yam etiologies tuaj yeem tsim kho.
Los ntawm genitourinary system
Hauv cov txiv neej, qhov txo qis hauv erection thiab qhov nce ntawm cov qog mammary yog qhov ua tau.
Los ntawm cov hlab plawv system
Tej zaum qhov ua rau cov ntshav siab poob, mob thrombosis vim yog lub cev qhuav dej, ua kom cov hlab ntsha tseem ceeb, txwv tsis pub cov ntshav khiav, viav vias phab ntsa thiab Raynaud's syndrome.
Endocrine system
Nws yog qhov ua tau ntawm txoj kev xav kom nce ntau ntxiv ntawm cov tshuaj tiv thaiv antidiuretic.
Ntawm ib sab ntawm daim siab thiab cov hnyuv
Hauv qee qhov xwm txheej, cytolytic ua rau lub siab ua rau lub cev yuav ua rau tuag taus. Muaj qhov nce ntxiv ntawm cov qib bilirubin hauv cov ntshav thiab tshwm sim ntawm kev paub txog tus mob cholecystitis.
Kev ua xua
Kev ua xua rau qhov tsis haum yog pom los ntawm cov tsos mob ntawm daim tawv nqaij.
Kev ua xua rau qhov tsis haum yog pom los ntawm cov tsos mob ntawm daim tawv nqaij.
Los ntawm cov leeg musculoskeletal thiab cov leeg mob sib kis
Tus neeg tuaj yeem tuaj yeem hnov mob thiab tsis muaj zog ntawm cov leeg.
Los ntawm ib sab ntawm cov metabolism
Hauv cov rooj plaub tshwj xeeb, muaj kev poob qis hauv cov ntaub so ntswg ua kom qabzib, vim cov ntshav qab zib cov ntshav nce ntxiv. Kev ua txhaum ntawm cov metabolism hauv dav dav, urea cov ntsiab lus hauv cov ntshav ntshav nce ntxiv, gout aggravates thiab anorexia nthuav dav. Tsis tshua muaj neeg mob, hypokalemia thiab metabolic acidosis muaj.
Los ntawm lub cev tiv thaiv kab mob
Tej zaum qhov kev txhim kho ntawm txoj kev xav tshuaj nyob rau hauv kev sib txuas nrog kev nce ntxiv ntawm lub titer ntawm cov tshuaj tiv thaiv kev ua kom tsis haum. Txais Txais Lub Cim Zaum tuaj yeem ua rau mob ntsej muag, ntsej muag plab hnyuv, nqaj thiab tus nplaig.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Vim tias qhov pom tshwm sim tsawg dua thiab qhov tsis nco qab, tus neeg mob yuav tsum tau ceev faj thaum tsav tsheb cov cuab yeej lossis cov tsav tsheb uas yuav tsum muaj lub siab siab ntawm psychomotor cov kev cuam tshuam thiab nce siab.
Vim tias qhov pom ua rau txo qis thiab qhov tsis nco qab, tus neeg mob yuav tsum tau ceev faj thaum tsav tsheb cov cuab yeej lossis cov tsheb.
Cov lus qhia tshwj xeeb
Ua ntej npaj kev cuam tshuam txog kev phais mob, nws yog qhov yuav tsum ceeb toom rau tus kws phais neeg ua haujlwm thiab tus kws tshuaj loog rau txoj haujlwm txog kev kho mob nrog ACE inhibitor. Qhov no yog qhov tsim nyog txhawm rau tiv thaiv kev poob hauv cov ntshav siab thaum lub sijhawm ua haujlwm.
Siv thaum cev xeeb tub thiab lactation
Vim tias qhov ua tau teratogenic thiab fetotoxic muaj txiaj ntsig, cov tshuaj tsis raug xaj rau cov poj niam cev xeeb tub. Muaj kev pheej hmoo ntawm kev mob plab intrauterine hauv tus me nyuam hauv plab.
Thaum kho, koj yuav tsum tsis txhob pub mis niam.
Teem Sij Hawm Ntxiv rau cov menyuam
Vim tias tsis muaj cov ntaub ntawv ntawm cov nyhuv ntawm Tritace rau tib neeg lub cev thaum lub sijhawm kev txhim kho, cov tshuaj no yog sib kis hauv cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Siv rau lub sijhawm qub
Cov neeg laus tsis tas yuav hloov pauv ntawm tus qauv kho.
Cov neeg laus tsis tas yuav hloov pauv ntawm tus qauv kho.
Daim ntawv thov rau lub raum khiav tsis zoo
Cov neeg mob uas tau mob me raum mus rau mob raum yuav tsum saib xyuas cov haujlwm ntawm cov khoom nruab nrog cev thaum kho.
Siv rau lub siab ua haujlwm tsis zoo
Cov yeeb tshuaj yog txwv rau siv los ntawm cov neeg muaj lub siab ua tsis zoo.
Noj ntau dua ntawm Tritace Ntxiv
Cov duab kho mob ntawm kev noj ntau dhau nthuav qhia nws tus kheej hauv kev tsim txom los ntawm tus neeg saib xyuas hypotensive thiab yog tus cim los ntawm cov tsos mob ntawm cov tsos mob hauv qab no:
- polyuria, uas nyob rau hauv cov neeg mob uas muaj benign prostatic adenoma lossis lwm yam ua tsis taus cov zis tawm provokes kev loj hlob ntawm stagnation ntawm tso zis nrog kev ntxhov siab ntawm lub zais zis;
- bradycardia, arrhythmia;
- cuab yeej paug vasodilation;
- ua txhaum ntawm cov dej-electrolyte metabolism;
- tsis meej pem thiab tsis nco qab nrog txoj kev txhim kho tom qab;
- mob leeg;
- txoj hnyuv du ua rau lub cev tsis ua haujlwm.
Yog tias tsawg dua 30-90 feeb tau dhau mus txij li thaum noj tshuaj ntsiav, nws yog qhov tsim nyog rau tus neeg mob ua kom qaug zog thiab ntuav lub plab. Tom qab cov txheej txheem, tus neeg mob yuav tsum noj ib qho adsorbent kom qeeb ntawm qhov nqus ntawm cov khoom nquag. Nrog rau bradycardia loj heev, nws yog ib qhov tsim nyog yuav tau qhia txhawm rau 1-2 mg ntawm adrenaline los yog tsim kom muaj qhov tsis txaus siab ib ntus. Thaum noj ntau dhau, nws yog ib qho tsim nyog yuav tsum tswj hwm cov ntshav dej creatinine qib thiab ntshav siab thaum kho cov tsos mob.
Nrog rau kev noj tshuaj ntau dhau hwv, mob leeg yuav tuaj yeem tshwm sim.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev tswj hwm tib lub sijhawm ntawm Tritace nrog thiazides, cov concentration ntawm cov roj cholesterol hauv cov ntshav cov ntshav yuav nce ntxiv.
Contraindicated kev sib txuas ua ke
Kws tshuaj tsis sib haum yog pom nrog cov tib neeg siv aliskiren thiab angiotensin II receptor antagonists. Hauv rooj plaub tom kawg, kev tswj hwm yog contraindicated nyob rau hauv cov neeg mob uas mob ntshav qab zib polyneuropathy. Aliskiren tsis yog kws kho rau kev mob raum mus rau lub raum tsis ua haujlwm.
Tsis pom zoo kev sib txuas ua ke
Ua ke nrog tus neeg sawv cev tiv thaiv kab mob nrog kev noj tshuaj tsaug zog, ntsev ntsev, tacrolimus nrog sulfamethoxazole yuav tsum tsis txhob muab tshuaj.
Tej kev sib txuam uas xav tau ceev faj
Nws yog ib qho tsim nyog yuav tau soj ntsuam qhov ntsuas kev nyab xeeb thaum mus ntsib:
- tricyclic cov tshuaj tiv thaiv kab mob;
- lwm cov tshuaj tiv thaiv kab mob siab;
- barbituric acid derivatives;
- cov nyiaj txiag rau cov tshuaj loog;
- sodium tshuaj dawb;
- tshuaj diuretic;
- vasopressor sympathomimetics;
- allopurinol, cov tshuaj tiv thaiv kab mob, glucocorticosteroids, cytostatics;
- estramustine, heparin, vildagliptin;
- cov kab mob hypoglycemic.
Thaum lub sijhawm kev kho mob, cov tshuaj ethanol muaj npaj thiab dej cawv yuav tsum tsis txhob siv.
Nws yog ib qho tsim nyog kom tsum tsis txhob noj ethanol.
Cawv tau zoo
Thaum lub sijhawm kev kho mob, cov tshuaj ethanol muaj npaj thiab dej cawv yuav tsum tsis txhob siv. Thaum noj Tritace nrog ethanol hauv parallel, muaj kev pheej hmoo ntawm vau.
Analogs
Qhov kev hloov pauv mus rau lwm cov tshuaj tiv thaiv kev tiv thaiv kabmob yog ua raws kev saib xyuas ntawm tus kws kho mob, uas tuaj yeem muab tshuaj ib qho tshuaj hauv qab no ua kev hloov kho:
- Hartil-D;
- Amprilan NL;
- Amprilan ND;
- Wazolong H;
- Ramazid H.
Cov cim qhia tau yooj yim dua tuaj yeem nkag mus hauv tus nqi nqe - 210-358 rubles.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Muag rau kev mob nkeeg.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov tshuaj tuaj yeem ua rau orthostatic hypotension yog tias siv tsis raug. Rau kev nyab xeeb ntawm cov neeg mob hauv cov khw muag tshuaj, cov tshuaj muaj peev xwm tsuas yuav tau tom qab ntawv yuav tshuaj.
Nqe ntawm Tritac Ntxiv
Tus nqi nruab nrab rau 5 mg ntsiav tshuaj yog 954-1212 rubles, nrog tshuaj ntau npaum 10 mg - 1537 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov ntsiav tshuaj tau tso cai cia rau qhov kub ntawm + 8 ... + 30 ° C nyob rau hauv qhov chaw sib cais los ntawm kev nqis tes ntawm lub hnub ci.
Hnub tas sij hawm
3 xyoos
Chaw tsim tshuaj paus
Sanofi Aventis, Ltalis.
Tritac Ntxiv Xyuas
Kev tshuaj xyuas zoo txog cov tshuaj qhia tau hais tias cov tshuaj tau tsim nws tus kheej hauv lub khw muag tshuaj.
Cov kws kho mob
Svetlana Gorbacheva, kws kho plawv, Ryazan
Nws yog qhov ua tau zoo hydrochlorothiazide-tus neeg sawv cev. Cov tshuaj ua kom zoo dua cov nyhuv antihypertensive. Kuv muab cov tshuaj rau kuv cov neeg mob tsuas yog mob ntshav ncig lub cev ib zaug ib hnub. Lub sijhawm kho yog ib leeg rau txhua tus neeg mob. Tsis muaj kev phiv pom. Cov neeg muaj mob raum tsis zoo yuav tsis pub noj tshuaj.
Cov neeg mob
Alexey Lebedev, 30 xyoo, Yaroslavl
Leej niam pib ua kom tawg nrog lub hnub nyoog. Vim tias cov ntshav siab tiv thaiv, cov tshuaj tiv thaiv kabmob ntshav yuav tsum noj txhua hnub. Ob peb hnub dhau los, Tritace tau txais kev pab ntev. Cov ntsiav tshuaj normalize ntshav siab zoo thiab tsis ua kev mob tshwm sim. Nrog rau kev siv lub sijhawm ntev, koj yuav tsum siv sijhawm so lossis nce ntau ntxiv, vim tias lub cev nres kom pom qhov tshwm sim ntawm cov ntsiav tshuaj. Qhov tsuas yog drawback yog qhov iab iab.
Elena Shashkina, 42 xyoo, Vladivostok
Tritace raug tso tawm rau nws niam tom qab mob stroke vim ntshav siab. Cov tshuaj pab tau - niam zoo, zoo siab hloov pauv tau nres. Niam siv qhov tsawg kawg nkaus kom cov tshuaj siv sijhawm ntev dua. Raws li tus kws kho mob pom zoo, tom qab ib hlis ntawm kev nkag mus ib zaug, nws tau siv nws li 1-2 lub lis piam. Qhov no yog qhov tsim nyog thiaj li tsis muaj kev phiv tshuaj thiab quav ntxiv.
