Abipim yog cov tshuaj zoo rau kev kho mob kis kab mob. Nws muaj cov nyhuv ua haujlwm tawm tsam ntau yam kabmob muaj sia. Thaum siv kom raug, nws tsis muaj kev cuam tshuam ntawm lub cev.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Kab Ntsig.
ATX
Tus lej ntawv yog J01DE01. Cov tshuaj siv nrog cov tshuaj tua kabmob thiab bactericidal kev txiav txim siab.
Abipim yog cov tshuaj zoo rau kev kho mob kis kab mob.
Tso cov ntawv thiab cov nyob ua ke
Muaj nyob hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj ntawm 500 mg. Muaj lyophilized hmoov rau txhaj tshuaj thiab koob txhaj tshuaj, uas yuav tsum tau tov rau hauv cov dej tsis huv rau kev txhaj tshuaj.
Pharmacological kev txiav txim
Nws yog rau cov khoom ua haujlwm tua kabmob ntawm 4 tiam. Tsim tshwj xeeb rau kev siv niam txiv. Nws ua tawm tsam cov kab mob gram-zoo thiab gram-tsis zoo, tshwj xeeb tshaj yog cov kab mob tiv thaiv cov tshuaj tua kab mob ntawm 2 thiab 3 tiam.
Txhawb kev tsim cov protein microbes, vim qhov ntawd ua rau lawv tuag. Ntxiv mus, qhov tsawg kawg nkaus ntawm kev txiav txim siab yog tsawg dua li ntawm cov tshuaj analogues, uas tso cai rau koj siv cov tshuaj tsawg dua thiab siv cov koob tshuaj tsawg dua.
Nquag tawm tsam tej yam muaj sia:
- Staphylococcus aureus (suav nrog cov kab mob uas tsim cov beta-lactamase);
- S. hominis, S. Saprophyticus, thiab lwm yam kab mob txawv ntawm staphylococci;
- Tus kab mob Streptococcus pyogenes thiab agalactiae, suav nrog cov kab mob uas tiv taus Penicillin;
- Streptococcus mob ntsws thiab lwm yam kab mob uas ua rau mob ntsws;
- Enterococcus faecalis thiab lwm hom kab mob enterobacteriaceae;
- gram-negative aerobic muaj sia: Pseudomonas spp, Enterobacter spp. (suav nrog E. cloacae, E. aerogenes, E. sakazakii), Proteus spp. (suav nrog P. mirabilis, P. vulgaris), Acinetobacter calcoaceticus (suav nrog subfamilies Antratus, Ioffi), Aeromonas hydrophila, Capnocytophaga spp., Citrobacter spp. (suav nrog C. diversus, C. freundii), Campylobacter jejuni, Gardnerella vaginalis, Haemophilus ducreyi;
- H. khaub thuas thiab parainfluenzae;
- Neisseria gonorrhoeae;
- cov kab mob anaerobic: bacteroids, suav nrog melaninogenicus;
- Clostridium perfringens;
- Fusobacteria: Fusobacterium spp.
Abipim tau tsim tshwj xeeb rau kev siv niam txiv.
Cov tshuaj kuj tseem tuaj yeem siv tau yog tias nws tsis tuaj yeem tsim kom muaj cov pathogen. Cov cuab yeej no tau piav qhia los ntawm qhov tseeb tias cov tshuaj muaj zog tawm tsam ntau cov kab mob tseem ceeb.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog kom nqus tom qab kev siv niam txiv. Qhov nruab nrab nruab nrab ntawm cov nquag sib xyaw nce mus txog qhov siab tshaj 60 feeb tom qab txhaj, tom qab ntawd txo qis.
Cov ntsiab lus tshuaj ntawm cov tshuaj pom nyob rau hauv cov zis, cov kua tsib, peritoneal thiab prostatic secretions, hnoos qeev, bronchial zais cia. Qee qhov tshuaj tiv thaiv muaj nyob hauv appendix.
Ib nrab-lub neej ntawm cov nquag tivthaiv yog 120 feeb; ywj siab ntawm ntau npaum. Cumulation ntawm Abipim tsis pom txawm tias thaum siv cov koob tshuaj ntev rau lub sijhawm ntev, uas tso cai rau kev siv tshuaj los kho cov kab mob sib kis loj.
Hauv lub cev, nws tawg rau methylpyrrolidine, uas hloov mus rau hauv methylpyrrolidone oxide sai sai. Nws yog zais siv cov glomeruli ntawm ob lub raum. Feem ntau cov tshuaj tawm los ntawm cov zis thiab tsuas yog ib feem me me - nrog quav. Nws khi rau cov protein ntau los ntawm kwv yees li 20%.
Lub sijhawm ib nrab-tshem tawm tau nce ntxiv hauv cov neeg mob uas lub raum tsis ua haujlwm; lawv xav tau ib qho kev hloov kho koob tshuaj. Hauv lwm qhov xwm txheej, cov cim ntawm pharmacokinetics tsis hloov pauv.
Lub sijhawm ib nrab-tshem tawm tau ntau ntxiv hauv cov neeg mob uas lub raum tsis ua haujlwm.
Kev ntsuas rau siv
MP yog qhia rau:
- pathologies ntawm kev ua pa, pob ntseg, caj pas lossis ntswg;
- kis kab mob ntawm daim tawv nqaij thiab cov nqaij mos subcutaneous;
- mob plab zom mov;
- poj niam pathologies;
- ntshav tshuaj lom;
- ua npaws;
- mob txeeb zig;
- mob rau daim phiaj;
- kev tiv thaiv kev kis kab mob thaum lossis tom qab phais tas.
Cov Yuav Tsum Muaj
Muaj cov contraindications rau noj:
- cov tshuaj tiv thaiv tsis haum rau cefepime thiab L-arginine, ib qho yeeb tshuaj los ntawm cov lej ntau ntawm cephalosporins;
- kev siv tshuaj tiv thaiv tsis haum rau cov lus qhia ntawm cephalosporins rau hauv lub cev;
- kev ua xua ntawm cov piam thaj oxidation.
Yuav ua li cas coj Abipim
Koob tshuaj rau cov laus yog 1 g nyob rau ib hnub. Nws yog txhaj rau hauv cov leeg nqaij lossis rau hauv cov hlab ntsha 2 zaug hauv ib hnub nrog rau kev so 12 teev. Lub sijhawm tswj hwm tib lub sijhawm yuav tsum raug saib xyuas kom tsis txhob muaj kev phiv thiab txhim kho cov txiaj ntsig kev kho mob.
Qhov ntau npaum li cas yuav txawv nyob ntawm seb hom pathogen thiab qhov siv ntawm cov txheej txheem sib kis.
Muaj ntau txoj kev xaiv tshuaj thiab cov hau kev siv tshuaj:
- nrog pathologies ntawm cov mob ntawm lub tso zis - los ntawm 0.5 mus rau 1 g 2 zaug hauv ib hnub;
- nrog rau lwm yam kev kis mob ntawm mob sib khuav-qib nruab nrab - 1 g ua intramuscularly lossis intravenously 2 zaug hauv ib hnub;
- nrog cov kab mob loj - 2 g ntawm cov tshuaj 2 zaug hauv ib hnub;
- hauv cov kev mob txaus ntshai - 2 g ib hnub, muab faib ua 3 koob tshuaj txhua 8 teev.
Txhawm rau txhawm rau tiv thaiv kev kis kab mob tom qab, nws yog ib qho tsim nyog siv tshuaj rau ib teev ua ntej kev phais mob (2 g txhua ib nrab teev), thiab tom qab ua haujlwm tiav, ib qho ntxiv 0.5 g ntawm cov tshuaj yog txhaj rau hauv cov hlab ntsha. Yog tias xav tau kev cuam tshuam ntev ntev, ces yuav tsum tau txhaj tshuaj ntxiv 12 teev tom qab thawj zaug muab thawj zaug.
Kev txhaj tshuaj Intramuscular yog qhov zoo dua, nrog lub koob raug tsav mus tob rau hauv cov leeg nqaij.
Hauv kev mob nyhav, kev tswj hwm ntawm Abipim yog qhov tsim nyog.
Nws yog txhaj rau hauv cov leeg nqaij lossis rau hauv cov hlab ntsha 2 zaug hauv ib hnub nrog rau kev so 12 teev.
Nrog ntshav qab zib
Nrog hyperglycemia, tus neeg mob tus mob yuav tsum tau saib xyuas tas li.
Phiv tawm ntawm Abiprim
Cov kev mob tshwm sim tuaj yeem tshwm sim:
- kev tiv thaiv tau ntau ntxiv, suav nrog kev poob siab anaphylactic thiab mob hlwb;
- hnoos, txog siav thiab mob caj pas zoo li mob caj pas;
- nce lub plawv dhia;
- xeev siab
- ntuav
- zawv plab
- candidiasis hauv lub qhov ncauj kab noj hniav;
- vaginitis;
- ntxhov siab, insomnia, convulsions;
- kab mob siab thiab mob tawv nqaij txhawm rau tiv thaiv keeb kwm ntawm qhov kev tiv thaiv kev tawm ntawm cov kua tsib;
- mob hauv thaj tsam lumbar thiab pob qij txha;
- kev tsis xis nyob sab nraub qaum thiab hauv siab;
- cov kab mob ua pa;
- khaus khaus ntawm qhov chaw mos, qhov tsos ntawm thrush;
- qaug dab peg zoo li mob vwm;
- neutropenic kub taub hau;
- erythema;
- tsis nco qab;
- hws
- txo qis hauv cov lej ntawm leukocytes thiab / lossis platelets.
Ntawm qhov chaw txhaj tshuaj, yuav muaj qhov mob, o, liab liab, o. Tej zaum yuav muaj kev hloov pauv hauv qhov ntsuas pom ntawm cov ntshav biochemical.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
MP tuaj yeem cuam tshuam rau kev ua haujlwm ntawm lub paj hlwb. Rau lub sijhawm kho, nws yog qhov zoo dua rau qhov tsis kam tsav lub tsheb thiab ua haujlwm nrog cov kev tawm tsam uas yuav tsum muaj kev saib xyuas ntau ntxiv.
Cov lus qhia tshwj xeeb
Hauv cov neeg mob uas muaj kev pheej hmoo ntawm cov mob txhab ntxiv nrog keeb kwm ntawm pob txha hloov, qhov tsawg dua ntawm MP kev ua ub no tshwm sim. Kev kho mob nrog Abipim yuav tsis muaj txiaj ntsig thiab tsis muaj txiaj ntsig, yog li, kev xaiv tsa ntawm lwm tus neeg sawv cev yog tsim nyog. Hauv qhov no, tus neeg mob tuaj yeem txhim kho neutropenia vam meej, yog li ntawd, thaum kho, nws yog ib qho tsim nyog los soj ntsuam ntshav tas li.
Ua ntej pib kev kho mob, nws yog qhov yuav tsum tau txiav txim siab seb tus neeg mob puas tau muaj kev cuam tshuam sai rau cefepime thiab lwm yam cephalosporins. Txhua yam kev phiv tsis haum, xws li cov tshuaj yuav tsum tau ua kom zoo. Yog tias muaj qhov tsis haum tshwm sim, qhov kev txais tos yog maj nrawm.
Nrog rau cov tsos ntawm cov kev pom tshwm sim hnyav, tus neeg mob yuav tsum muab tshuaj Adrenaline.
Yog tias pom muaj mob hnyav, tus neeg mob yuav tsum raug tswj hwm Adrenaline lossis Norepinephrine.
Kev siv cov tshuaj tua kabmob ua haujlwm nrog ntau qhov kev pom zoo tuaj yeem ua rau kev txhim kho pseudomembranous o ua rau lub plab hnyuv loj. Qhov no tuaj yeem ua rau raws plab. Cov ntaub ntawv me me muaj peev xwm kis tau sai dhau uas tsis muaj kev kho tshwj xeeb. Nrog rau lwm txoj kev ntawm kev ua haujlwm ntawm cov hnyuv, cephalosporins yuav tsum tau ua tib zoo kho, saib xyuas tib neeg cov tshuaj tiv thaiv.
Kev siv tshuaj noj tuaj yeem pab txhawb kev tsim kho kev ua si.
Kev siv ntawm ib qho tshuaj tua kab mob antimicrobial, suav nrog thiab Abipima, nqa nrog nws ua kom muaj kev hloov pauv ntawm cov kab hauv av, uas ua rau pom kev ntawm clostridia hauv txoj hnyuv. Cov txheej txheem no pab txhawb kev txhim kho cov tshuaj tua kab mob sib kis.
Siv rau lub sijhawm qub
Lub hnub nyoog tsis yog qhov ntsuas pom kev hloov pauv ntau npaum li cas. Tab sis koj yuav tsum txo cov tshuaj rau cov neeg laus nrog rau kev hloov lub raum ua haujlwm.
Txiag tej menyuam
Cov cuab yeej tuaj yeem siv rau menyuam yaus txij li ib hlis. Hauv qhov no, qhov koob tshuaj tau xaiv nruj me ntsis raws lub hnub nyoog ntawm tus menyuam thiab qhov ntsuas ntawm qhov sib kis ntawm cov txheej txheem sib kis.
Cov neeg uas hnyav 40 kg lossis ntau dua tsis tas yuav hloov pauv koob tshuaj.
Siv thaum cev xeeb tub thiab lactation
Kev siv ntawm Abipim yog qhov tsis lees paub hauv lub sijhawm 1 lub hlis. Yav tom ntej, MP tau sau tseg yog tias cov txiaj ntsig zoo dua li qhov pheej hmoo txaus ntshai.
Cov tshuaj muaj peev xwm nkag mus rau hauv niam mis thiab ua rau kev loj hlob cuam tshuam ntawm tus menyuam, yog li ntawd nws raug nquahu kom tsis txhob pub mis niam thaum kho nrog tus MP no.
Daim ntawv thov rau lub raum khiav tsis zoo
Nws yog ib qho tsim nyog yuav tau kho qhov tshuaj ntawm cov tshuaj txhawm rau kom tiv thaiv kev lom. Nrog rau kev txo tawm ntawm creatinine qhov kev tshem tawm, cov koob tshuaj yog txo kom thiaj li them nyiaj rau cov qeeb tso tawm. Hauv cov kab mob hauv lub raum ntau, nws yuav tsum tau sau ntawv los kho cov tshuaj kho kom txo tau cov txiaj ntsig tsis zoo ntawm lub raum pathology.
Hauv cov neeg mob kev txom nyem los ntawm lub raum pathologies, cov kev mob tshwm sim tom qab tau sau tseg:
- tabkaum thiab tsis meej pem, hais tawm lus tso dag, hnov ntsej muag, tsis nco qab;
- myoclonus;
- cramps.
Xws li cov kev phom sij txog lub neej tau sau cia feem ntau hauv cov neeg uas tau noj Abipim ntau kawg.
Siv rau lub siab ua haujlwm tsis zoo
Kev ceev faj yuav tsum tau siv rau thaum muaj mob rau daim siab, mob siab thiab mob ntsws.
Kev Siv Abiprim
Kev noj tshuaj ntau dhau ntawm cov tshuaj yuav ua tau yog tias tus neeg mob tau siab dhau qhov kev pom zoo thiab kev tso cai noj tshuaj. Hauv txhua kis ntawm kev noj ntau dhau, cov cim qhia txog kev mob tshwm sim. Lwm yam kev qhia ntawm overdose:
- mob hlwb thiab ua kom pom cov yam ntxwv ntawm tus yam ntxwv mob;
- kev ua cov kev coj ua;
- coma
- asthenia;
- neeg ruam;
- lub cev muaj zog thiab cov ua haujlwm tsis muaj zog.
Nyob rau hauv rooj plaub ntawm kev siv ntau dhau, tswj hwm kev siv tshuaj yog nres. Tsis muaj cov tshuaj tiv thaiv tshwj xeeb tau tsim. Koj tuaj yeem kho qhov kev tshem tawm sai sai ntawm kev siv tshuaj kho mob uas siv cov txheej txheem hemodialysis. Thaum muaj kev fab loj heev tshwm sim, nws yog ib qhov tsim nyog yuav tau qhia cov kev daws teeb meem ntawm Adrenaline thiab Noradrenaline.
Kev cuam tshuam nrog lwm yam tshuaj
Nws yog ib qho tsim nyog los saib xyuas kev ua haujlwm ntawm lub raum, tshwj xeeb tshaj yog tias tus neeg mob siv lwm yam tshuaj nephrotoxic. Qhov no yog qhov tseem ceeb thaum noj furosemide thiab lwm yam tshuaj diuretics. Qee qhov xwm txheej, nrog kev sib txuam ntawm cov tshuaj no, ib qho nce ntawm nephrotoxicity tau sau tseg.
Tshaj rau cov tshuaj zoo li no:
- saline daws;
- piam thaj tov;
- piam thaj nrog lactate.
Nws tsis pom zoo kom nkag mus rau tib lub sijhawm:
- Metronidazole;
- Vancomycin;
- Gentamicin;
- Tobramycin sulfate;
- Netromycin sulfate.
Cawv tau zoo
Tsis haum nrog haus cawv thaum siv. Kev siv dej cawv ua rau muaj qhov tshwm sim ntau ntxiv ntawm qhov tshwm sim tsis zoo thiab ua rau lub raum puas tsuaj. Tej zaum tau nce hepatotoxicity.
Analogs
Cov tshuaj ntawm cov tshuaj yog:
- Cuas Tshuas;
- Zebopim;
- Cefuroxime;
- Agicef.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Muag los ntawm cov tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Hauv ntau lub tsev muag tshuaj, cov khw muag tshuaj online tuaj yeem yauv tau yam tsis tas yuav tshuaj.
Nqe rau Abipim
Tus nqi hauv cov khw muag tshuaj ntawm Ukraine yog kwv yees li 200-220 UAH. rau ib pob ntawm 10 ampoules; nyob rau hauv Russia - txog 650 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov khoom yuav tsum muab tso rau hauv qhov chaw tsaus thiab txias qhov chaw deb ntawm cov menyuam yaus. Tsis khov.
Hnub tas sij hawm
Haum rau 3 xyoos txij li hnub tawm.
Chaw tsim tshuaj paus
Ua los ntawm Abryl Formulations Pvt Ltd./Abril Formulations Pvt. Ltd., Is Nrias teb.
Kev Tshawb Xyuas Txog Abipime
Irina, hnub nyoog 35 xyoo, Nizhny Novgorod: "Nrog kev pab ntawm Abipim, Kuv tuaj yeem kho mob cystitis loj heev, uas tsis tau muaj kev kho mob nrog lwm tus neeg sawv cev rau tshuaj tua kabmob. Kuv tau txais cov tshuaj rau 10 hnub (2 koob tshuaj 500 mg ib zaug). ib qho kev hloov kho ruaj khov los txhawb kev tiv thaiv kab mob thiab tiv thaiv kom tsis txhob muaj mob rov rau ntawm lub zais zis. "
Oleg, hnub nyoog 40 xyoo, Komsomolsk-on-Amur: “Nrog Abipim pab kho nws tus mob ntsws mob hnyav. Nws tau muab tshuaj rau 10 hnub. Nws twb tau los ntawm 3 hnub ntawm kev kho mob, tus tsos mob ntawm tus kab mob tsawg zuj zus, hnoos thiab kub taub hau ploj mus. Tsis muaj kev phiv thaum lub sijhawm muab tshuaj. Kuv tabtom kawm ib chav ntawm kev rov ua haujlwm li qub hnyuv microflora, vim hais tias tom qab Abipim nws tig los ua kev ntxhov siab me ntsis. "
Polina, hnub nyoog 28 xyoo, Nizhnevartovsk: "Cov tshuaj tau pab tshem tawm tus kabmob kis kabmob ntawm poj niam lub cev xeeb tub. Cov tshuaj tua kabmob no tau pom zoo tau zoo; nws ua rau muaj kev txhim kho rau hnub 3 ntawm txoj kev kho. Kuv tau mus kho ib lub limtiam. mob thiab mob thaum tso zis. "
