Nrog ntshav qab zib, ib tug neeg xav tau ib koob tshuaj txhua hnub ntawm pancreatic hormone.
Vim tias qhov tseeb tias lub cev no tsim cov tshuaj hormones me ntsis lossis tsis muaj peev xwm ua tau txhua yam, cov kws kho mob tau sau ntawv tawm tshuaj tshwj xeeb rau cov tshuaj insulin. Ib qho ntawm cov no yog Humulin.
Hauv tsab xov xwm no, koj tuaj yeem kawm paub ntau ntxiv txog nws muaj pes tsawg leeg, kev piav qhia, kev nqis tes ua pharmacological, kev taw qhia rau kev siv thiab nws cov hom loj.
Muaj pes tsawg leeg
Raws li cov ntaub ntawv hauv cov lus qhia rau cov tshuaj, kwv yees li ib milliliter ntawm cov tshuaj hu ua Humulin muaj 100 IU ntawm tib neeg cov tshuaj insulin. Cov khoom xyaw tseem ceeb yog 30% solulin insulin thiab 70% insulin isophan.
Cov tshuaj tiv thaiv ntxiv muaj rau cov hauv qab no:
- distilled metacresol;
- phenol;
- sodium hydrogen phosphate heptahydrate;
- hydrochloric acid;
- glycerol;
- zinc oxide;
- protamine sulfate;
- sodium hydroxide;
- lim dej.
Kev piav qhia ntawm cov sib txawv ntawm kev tso tawm cov tshuaj Humulin
NPH
Humulin NPH yog qhov nruab nrab ntawm tib neeg lub cev insulin. Nws muaj daim ntawv ntawm qhov kev ncua ntawv npaj rau lub subcutaneous thawj coj.
Nws txawv hauv cov xim dawb, dhau li nws yog cov stratified zoo, sib sau ua qhov dej muaj npluav thiab muaj cov xim tsis zoo lossis cov xim tsis muaj xim lossis yuav luag tsis muaj qhov sib xyaw. Cov nag lossis daus nws tus kheej tau zoo thiab ncaj yooj yim resuspended nrog maj mam co.
Kev Ncua Sijhawm Humulin NPH
Qhov insulin no, uas zoo tib yam rau tib neeg, yog qhia rau cov ntshav qab zib muaj qee yam cim rau kev siv. Nws kuj tseem siv tau rau cov kab mob ntshav qab zib tshiab uas tau tshawb pom. Cov kws kho mob pom zoo kom siv nws rau kev txhaj tshuaj thaum cev xeeb tub nrog lub cev tsis hnov lus.
Raws li txoj cai rau kev npaj qhov kev daws teeb meem rau kev tswj hwm, lub voos thiab vials ntawm Humulin NPH ua ntej kev siv ncaj qha yuav tsum tau muab nruab nrab ntawm xib teg ob peb zaug thiab shaken, tig mus txog 190 °.
Ib zaug ntxiv kaum yuav tsum ua kom zoo ib yam rau resuspend cov khoom neeg tsim tshuaj lom neeg rau ntawm lub txiav rau ib lub xeev txog thaum kev daws teeb meem ua homogeneous.
Nws yuav tsum zoo li cov huab lossis kua mis. Tsis txhob co nws muaj zog, vim tias qhov no tuaj yeem ua rau pom kev ua npuas, uas yuav tiv thaiv qhov tseeb teeb tsa ntawm qhov tsim nyog xav tau.
Nws yog ib qho tseem ceeb heev uas yuav tau ua tib zoo tshuaj saib lub pob cartridges thiab vials ntawm cov tshuaj ua ntej siv. Nws tsis pom zoo kom siv cov tshuaj insulin, uas muaj ntau yam plaub ya ri lossis dawb hauv nws cov kev daws.
Tshwj xeeb yog hais tias, tom qab sib tov sib xyaw, koj pom cov khoom tawg yooj yim dawb uas ua rau hauv qab thiab phab ntsa ntawm lub thawb. Feem ntau nws zoo li cov qauv frosty. Lub thawv lub thawv nws tus kheej ua rau nws tsis tuaj yeem sib xyaw nws cov ntsiab lus nrog lwm hom insulin. Cov cuab yeej no tsis yog npaj rau lwm qhov kev siv.
Tag nrho cov ntsiab lus ntawm lub vial yuav tsum tau sau rau hauv cov tshuaj insulin, uas sib raug rau cov tshuaj ntawm cov tshuaj tov.
Tom ntej no, ib qho tshuaj yuav tsum tau maj mam muab tshuaj raws li cov lus qhia uas txuas rau nws.
Thaum siv cartridges, nws yog ib qho tseem ceeb kom paub koj tus kheej nrog cov cai rau lawv siv. Nws yog ib qho tseem ceeb uas yuav tsum ua txhua yam kom raug: pib los ntawm kev rov ntim daim cartridge nws tus kheej thiab xaus nrog txuas tus koob.
Cov kws kho mob tshwj xeeb pom zoo kom siv cov tshuaj Humulin tsis tu ncua nrog Humulin NPH. Rau qhov no, insulin luv luv yuav tsum tau kos rau hauv cov koob txhaj ua ntej kom tiv thaiv cov insulin ua yeeb yam ntev dua los ntawm nkag mus rau hauv lub taub ntim.
Ntxawg
Humulin Li Niaj Zaus yog tib neeg tsim cov tshuaj insulin DNA. Nws yog suav tias yog luv-spectrum artificial pancreatic hormone tshuaj.
Cov kev ua tseem ceeb ntawm cov tshuaj no suav hais tias yog kev tswj ntawm cov txheej txheem hauv kev zom zaub mov hauv cov khoom noj uas muaj cov khoom noj carbohydrates. Ntawm lwm yam, cov tshuaj muaj lub zog anabolic zoo.
Humulin Tsis tu ncua
Hauv cov leeg nqaij thiab lwm cov ntaub so ntswg (tshwj tsis yog lub hlwb), tib neeg cov insulin provokes qhov tshwm sim ntawm kev thauj mus los sai hauv qabzib thiab amino acids, thiab kuj tseem ua rau muaj protein ntau anabolism.
Qhov cov tshuaj tshwj xeeb no txhawb kev hloov pauv ntawm cov piam thaj rau daim siab glycogen, thiab tseem inhibits gluconeogenesis. Nws kuj ua rau kev hloov pauv ntawm cov piam thaj ntau dhau mus ua cov rog rog.
Cov tshuaj no yog sau rau cov ntshav qab zib yog tias muaj qee qhov taw qhia rau kev kho tshuaj insulin tam sim ntawd.
Nws tseem tuaj yeem siv thawj zaug kuaj tus kabmob no.
Nws raug tso cai siv Humulin Tsis tu ncua thaum nqa tus menyuam nrog tus kabmob endocrine no (nrog rau ib tus uas suav tias yog insulin-ywj siab). Raws li kev npaj ntawm qhov kev daws teeb meem rau kev tswj hwm, cov cai yeej tau zoo ib yam rau Humulin NPH.
Tshuaj insulin M3
Humulin M3 yog tib neeg cov tshuaj insulin uas zwm rau hauv pab pawg ntawm cov neeg ua yeeb yaj kiab pancreatic ntawm cov tshuaj nruab nrab.
Humulin M3
Cov lus qhia rau kev siv nrog cov tshuaj no ua tau zoo sib xws nrog cov ntawm thawj ob ntau yam ntawm cov tshuaj insulin. Cov qib noj tshuaj tau txiav txim siab tsuas yog ib tus zuj zus, nyob ntawm theem thiab qhov mob hnyav.
Pharmacological kev txiav txim
Txhua qhov suav hais tias yog analogues ntawm tib neeg cov tshuaj hormones, uas tsim tawm los ntawm cov txiav, muaj cov nyhuv tshuaj zoo ib yam. Lawv yog tag nrho DNA tso tshuaj insulin.
Qhov sib txawv ntawm cov tshuaj muaj nyob rau hauv sib txawv durations ntawm kev txiav txim:
- Humulin NPH suav tias yog tshuaj insulin ntawm lub sijhawm nruab nrab;
- Humulin Tsis tu ncua yog yeeb tshuaj pancreatic hormone luv-luv;
- Humulin M3Cov. Cov tshuaj no, zoo li thawj hom, muaj lub sij hawm ua nruab nrab.
Kev taw qhia thiab contraindications
Raws li tau sau tseg ua ntej, txhua yam suav tias yog hom tshuaj insulin, uas zoo ib yam rau tib neeg, muaj cov cim qhia tau thiab contraindications rau kev siv.
Kev npaj tshuaj insulin yog tshuaj rau cov kab mob thiab mob ntawm lub cev:
- ib qho kab mob endocrine hu ua mob ntshav qab zib nrog qee yam cim rau kev kho insulin tam sim;
- thawj kuaj mob ntshav qab zib;
- coj menyuam yaus nyob ntawm qhov mob no ob hom.
Raws li rau contraindications, cov tshuaj tsis pom zoo rau stabilization ntawm lub zwj ceeb ntawm lub cev nrog rau mob xws li:
- cov piam thaj hauv ntshav tsawg
- lub xub ntiag ntawm kev ua kom lub cev tsis zoo rau cov tshuaj hormone ntawm lub txiav los yog mus rau ib qho ntawm cov tshuaj ntawm cov tshuaj.
Xyuas
Raws li kev tshuaj xyuas ntawm cov neeg uas siv cov tshuaj insulin hloov pauv no, lawv ua tau zoo heev. Raws li txoj cai, tus neeg sib txawv hauv cov kev ua ntawm cov tshuaj no nyob ntawm ntau yam, xws li koob tshuaj, xaiv qhov chaw txhaj tshuaj thiab kev ua haujlwm ntawm tus neeg mob.
Sab sij huam
Qhov tsis zoo lub siab xav nyob rau hauv ib cov tshuaj ntawm ntau hom yuav tsuas yog cuam tshuam nrog lub xub ntiag ntawm hypoglycemia.
Raws li koj paub, tus mob no ntawm lub cev tuaj yeem ua rau tsis nco qab thiab txawm tuag.
Cov kev txhaum fab hnyav tuaj yeem tshwm sim nrog cov tsos mob pom zoo, xws li o, khaus, thiab hyperemia ntawm thaj chaw txhaj tshuaj.
Noj ntau dhau
Cov tsos mob ntawm kev haus ib ce yog cov hauv qab no: qhov kev txo qis hauv cov piam thaj hauv lub cev, uas nrog nws tsis muaj zog, nrog rau kev tawm hws.Ntxiv rau, tus neeg mob sau tseg daim tawv daj daj, mob taub hau heev, tshee tshee, ntuav, thiab tsis meej pem.
Hauv qee qhov kev tshwj xeeb, piv txwv, nrog saib xyuas ntshav qab zib kom sai, cov cim ntawm kev tuaj yeem ua ntej ntawm hypoglycemia tuaj yeem hloov pauv. Raws li txoj cai, cov tsos mob me me ntawm kev txo cov ntshav qab zib tuaj yeem raug tshem tawm los ntawm kev noj cov kua nplaum.
Feem ntau, yuav tsum tau tshuaj xyuas cov koob tshuaj insulin, khoom noj khoom haus, thiab kev tawm dag zog thaum xub thawj. Kev kho ntawm cov ntshav qog nruab nrab yuav tsum tau nqa tawm siv cov kev siv tshuaj intramuscular thiab subcutaneous ntawm glucagon, tom qab ntawd los ntawm kev noj zaubmov carbohydrates.
Yuav muaj ntau yam ua rau cov ntshav qab zib tsawg, uas yog nrog rau coma, mob nriaj, thiab mob puas hlwb, raug tshem tawm los ntawm kev txhaj tshuaj rau ntshav qab zib los yog kab mob ntshav qab zib los yog tso ntshav tshuaj ntawm cov tshuaj dextrose.
Tom qab qhov siab tshaj plaws ntawm kev nco qab, tus neeg mob ntawm endocrinologist yuav tsum tau muab cov khoom noj uas muaj nplua nuj nyob hauv cov carbohydrates.
Txhawm rau kom tsis txhob noj tshuaj ntau dhau, koj yuav tsum nco ntsoov tias yog tias muaj teeb meem loj rau lub raum thiab mob siab, nws yog ib qho tseem ceeb kom txo qis cov tshuaj no. Qhov no yog vim qhov tseeb tias nrog cov mob no, qhov kev xav tau rau insulin yog txo qis dua.
Related videos
Cov lus qhia rau kev siv tshuaj yeeb tshuaj Humulin hauv video:
Qhov kev qhia rau Khumulin hais txog qhov tseeb tias thaum lub sij hawm cov ntshav qab zib nws cov ntshav qab zib tsis txaus, muaj peev xwm mloog zoo tuaj yeem ua rau tsis zoo. Nyob rau tib lub sijhawm, muaj qhov txo qis ntawm cov hlwb kev xav tsis tau. Qhov no tuaj yeem yog ib qho txaus ntshai nyob rau hauv qhov xwm txheej uas qhov peev xwm no xav tau nrawm (thaum tsav tsheb thiab tswj ntau cov txheej txheem nyuaj).
Cov neeg mob yuav tsum tau qhia rau sawv daws kom ceev faj kom tsis txhob tshwm sim ntawm cov ntshav qab zib tsawg tshaj plaws ntawm lub sijhawm tam sim no. Qee cov kws tshaj lij pom zoo kom tso tseg txoj kev tsav tsheb ib ntus.
