Yanumet ntsiav tshuaj rau ntshav qab zib hom 2

Yanumet ntsiav tshuaj rau kev siv yog hais txog cov tshuaj hypoglycemic uas siv los them rau cov mob ntshav qab zib hom 2. Nws cov hauj lwm zoo tau txhim kho los ntawm cov tsis sib xws ntawm cov khoom. Nws yog leej twg haum rau thiab yuav siv nws li cas?

Feem ntau nws tau sau tseg yog tias kev hloov kho lub neej thiab kev siv tshuaj kho mob metformin yav dhau los lossis kev kho mob tsis tau coj cov txiaj ntsig kev cia siab. Qee lub sij hawm nws tau raug teem rau cov neeg uas koom nrog kev ua kis las kom tswj hwm lawv cov glycemic profile. Ntxiv nrog rau kev paub ntxaws nrog cov lus qhia, ua ntej siv txhua kis, kws kho mob sab laj yog qhov yuav tsum tau ua.

Yanumet: muaj pes tsawg leeg thiab nta

Cov khoom xyaw ua si tseem ceeb hauv cov mis yog metformin hydrochloride. Cov tshuaj tau ntim hauv 500 mg, 850 mg lossis 1000 mg hauv 1 ntsiav tshuaj. Sitagliptin pabcuam ntawm cov tshuaj yog qhov tseem ceeb, hauv ib lub tshuaj ntsiav nws yuav yog 50 mg ntawm ib koob tshuaj metformin. Muaj cov zam rau hauv cov mis uas tsis muaj kev txaus siab nyob rau hauv cov nqe lus ntawm cov tshuaj muaj peev xwm.

Elongated convex capsules yog kev tiv thaiv los ntawm fakes nrog cov ntawv sau "575", "515" lossis "577", nyob ntawm qhov ntau npaum. Txhua pob ntawv cardboard muaj ob lossis plaub daim phiaj ntawm 14 daim. Cov tshuaj kws kho mob muab aws.

Lub thawv kuj tseem qhia txog lub txee lub neej ntawm cov tshuaj - 2 xyoo. Cov tshuaj uas tas sij hawm yuav tsum tau muab pov tseg. Qhov xav tau rau qhov chaw cia khoom yog tus qauv: qhov chaw qhuav tsis nkag rau lub hnub thiab cov menyuam yaus nrog lub ntsuas kub txog li 25 degrees.

Pharmacological tau

Yanumet yog qhov kev xav ua ke ntawm ob hom tshuaj qab zib ua kom muaj kev sib xyaw ua ke (sib ntxiv rau ib leeg) cov yam ntxwv: metformin hydrochloride, uas yog ib pawg loj ntawm cov loj, thiab sitagliptin, inhibitor ntawm DPP-4.

Synagliptin

Qhov khoom nruab yog npaj rau kev siv qhov ncauj. Cov txheej txheem ntawm kev ua ntawm sitagliptin yog ua raws li kev ua kom muaj zog ntau zuj zus. Thaum DPP-4 raug txwv, qib ntawm GLP-1 thiab HIP peptides, uas tswj cov ntshav qabzib homeostasis, nce ntxiv. Yog tias nws qhov kev ua tau zoo dua, incretins ua kom lub zog tsim cov kua dej siv cov β-hlwb. GLP-1 tseem ua rau kev txhim kho cov glucagon los ntawm α-cov hlwb lub siab. Qhov kev txiav txim siab zoo li no tsis zoo ib yam nrog lub hauv paus ntsiab lus ntawm cov tshuaj sulfonylurea (SM) chav kawm tshuaj uas txhim kho cov tshuaj insulin ntau dua ntawm txhua qib cov piam thaj.

Cov kev ua si zoo li no tuaj yeem ua rau cov ntshav qab zib tsis tsuas yog nyob rau hauv cov ntshav qab zib, tab sis kuj hauv cov neeg ua haujlwm noj qab haus huv.

DPP-4 enzyme inhibitor nyob rau hauv cov koob tshuaj pom zoo tsis thaiv qhov ua haujlwm ntawm PPP-8 lossis PPP-9 enzymes. Hauv chaw muag tshuaj, sitagliptin tsis zoo ib yam li nws cov tshuaj ntxiv: GLP-1, insulin, SM derivatives, meglitinide, biguanides, α-glycosidase inhibitors, γ-receptor agonists, amylin.

Metformin

Ua tsaug rau metformin, kev ua kom cov ntshav qab zib nyob hauv hom 2 mob ntshav qab zib ntau ntxiv: lawv cov concentration txo qis (ob qho tib si postprandial thiab hauv paus), insulin tsis kam. Qhov kev txiav txim siab ntawm cov tshuaj muaj txiaj ntsig yog txawv ntawm cov ntsiab cai ntawm kev ua haujlwm ntawm kev hloov pauv kho cov ntshav qab zib. Txwv tsis pub cov khoom tsim cov glucogen los ntawm lub siab, metformin txo qis nws nqus los ntawm cov hnyuv phab ntsa, txo cov tshuaj insulin tsis kam, ua kom muaj kev cuam tshuam peripheral.

Tsis zoo li cov tshuaj SM, metformin tsis ua rau muaj kev cuam tshuam ntawm hyperinsulinemia thiab hypoglycemia tsis yog rau cov neeg mob ntshav qab zib nrog hom 2, lossis tsis nyob hauv pawg tswj hwm. Thaum kho nrog metformin, insulin ntau lawm tseem nyob rau tib theem, tab sis nws qhov kev yoo mov thiab cov qib txhua hnub nyiam.

Cov tshuaj Pharmacokinetic

Cov tshuaj sib xyaw ua ke Yanumen yog bioequivalent rau ib qho sib cais kom tsawg ntawm cov koob tshuaj tsim nyog ntawm Januvia thiab Metformin.

Xuas

Lub bioavailability ntawm sitagliptin yog 87%. Kev siv ntawm cov khoom noj muaj roj ntau thiab cov khoom noj muaj lub cev tsis muaj txiaj ntsig tsis muaj kev cuam tshuam ntawm tus nqi ntawm kev nqus. Qib siab tshaj plaws ntawm cov tshuaj nyob hauv cov hlab ntshav yog tsau 1-4 teev tom qab nqus los ntawm kev mob hauv txoj hnyuv.

Lub bioavailability ntawm metformin rau ntawm ib plab khoob yog li 60% ntawm koob tshuaj 500 mg. Nrog ib qho hno ntawm koob tshuaj loj (txog 2550 mg), lub hauv paus ntsiab lus ntawm kev sib luag tau ua txhaum, vim tias tsis nqus qis. Metformin los ua haujlwm tom qab ob thiab ib nrab teev. Nws qib mus txog 60%. Qhov kawg ntawm metformin yog kaw tom qab ib hnub lossis ob hnub. Thaum noj mov, cov ua haujlwm ntawm cov tshuaj tsawg dua.

Kev xa Khoom

Qhov ntim ntawm kev faib tawm ntawm synagliptin nrog kev siv nrog 1 mg ntawm pawg pab pawg tswj hwm ntawm cov koom hauv kev sim yog 198 l. Cov qib ntawm khi rau cov ntshav protein yog sib txawv me - 38%.

Hauv cov kev sim zoo sib xws nrog metformin, pawg tswj hwm tau muab cov tshuaj rau hauv qhov ntau npaum li 850 mg, qhov faib tawm tib lub sijhawm tau ntau li 506 litres.

Yog tias peb piv nrog cov tshuaj ntawm cov chav kawm SM, metformin qhov tseeb tsis khi rau cov protein, ib ntus ib feem me me ntawm nws nyob hauv cov ntshav liab.

Yog tias koj noj cov tshuaj hauv cov txheej txheem ntau npaum, cov tshuaj tau nce mus txog qib siab (<1 μg / ml) hauv cov ntshav hauv ib hnub lossis ob. Raws li cov txiaj ntsig ntawm kev sim, txawm tias ntawm qhov txwv tsis pub tshaj tawm, qhov siab ntawm cov tshuaj nyob hauv cov ntshav tsis ntau tshaj 5 μg / ml.

Xaus

Txog li 80% ntawm cov tshuaj raug tso tawm los ntawm lub raum, metformin tsis yog cov tshuaj tiv thaiv hauv lub cev, hauv pawg tswj yuav luag tag nrho cov seem tshuav nyob hauv nws daim ntawv qub ib hnub. Tus kab mob siab Hepatic thiab ua rau hauv cov kiav txhab tag nrho yog qhaj. Sinagliptin raug tso tawm zoo ib yam (txog li 79%) nrog cov khoom noj me me. Thaum muaj teeb meem nrog lub raum, cov koob tshuaj ntawm Yanumet yuav tsum tau hais meej. Nrog cov kab mob hepatic pathologies, cov xwm txheej tshwj xeeb rau kev kho yog tsis xav tau.

Pharmacokinetics ntawm pawg tshwj xeeb ntawm cov neeg mob

1. Tus mob ntshav qab zib nrog hom 2. Tus txheej txheem ntawm kev nqus thiab kev faib ntawm sitagliptin zoo ib yam nrog cov txheej txheem hauv lub cev noj qab nyob zoo. Yog tias ob lub raum lub cev tsis sib xws, kev sib txawv hauv cov chaw muag tshuaj thaum siv ob koob tshuaj metformin hauv cov neeg mob ntshav qab zib thiab cov neeg ua haujlwm noj qab haus huv tsis pom. Kev cog qoob loo ntawm cov tshuaj hauv kev ua raws li cov qauv tsis suav siab.
2. Hauv lub raum tsis ua hauj lwm, Yanumet tsis muaj kws kho mob, vim tias cov tshuaj yuav luag txhua qhov dhau los ntawm lub raum, tsim kom muaj lub nra hnyav rau ob qho ntawm cov khoom tseem ceeb ntawd.
3. Hauv daim siab pathologies ntawm mob hnyav thiab mob hnyav, ib koob tshuaj sitagliptin tsis qhia txog qhov sib txawv hauv kev nqus thiab kev faib tawm. Tsis muaj cov ntaub ntawv hais txog cov txiaj ntsig ntawm kev noj tshuaj rau cov mob siab rau daim siab, tab sis kev kwv yees hauv qhov no tsis zoo. Raws li metformin, cov txiaj ntsig ntawm kev sim zoo sib xws tsis tau luam tawm.
4. Mob ntshav qab zib ntawm neeg laus. Cov hnub nyoog sib txawv muaj feem xyuam nrog kev mob raum, tom qab 80 xyoo, Janumet tsis qhia (tshwj tsis yog cov ntshav qab zib nrog rau kev tshem tawm ntawm cretatinin).

Rau leej twg nws yog qhia thiab rau leej twg nws tsis pom Yanumet

Cov tshuaj yog tsim los tswj hom ntshav qab zib 2. Nws tau sau tseg hauv qee kis tshwj xeeb.

1. Raws li ib qho ntxiv rau kev hloov kho hauv lub neej txhawm rau txhim kho glycemic profile ntawm cov ntshav qab zib, yog tias metformin monotherapy tsis muab 100% qhov tshwm sim.
2. Yanumet siv nyob rau hauv kev sib txuas ua ke nrog kev xaj ntawm SM, yog tias kev xaiv "metformin + kev noj tshuaj ntawm pawg SM + kev noj cov zaub mov qis thiab cov leeg nqaij" tsis zoo txaus.
3. Cov tshuaj sib xyaw ua ke, yog tias tsim nyog, nrog gamma receptor agonists.
4. Yog tias cov tshuaj insulin tsis ua tiav cov nyiaj qab zib, Yanumet raug tshaj tawm zoo ibyam.

Cov txheej txheem tsis haum hauv cov lus qhia yog raws li nram no:

• Cov tshuaj tiv thaiv tsis haum rau cov khoom xyaw ntawm cov mis mos;
• Coma (mob ntshav qab zib);
• Pathology ntawm lub raum;
• Kab mob sib kis;
• Txhaj tshuaj nrog tshuaj iodine (iv);
• Poob siab mob;
• Cov kab mob uas ua rau cov pa oxygen tsis txaus nyob rau hauv cov ntaub so ntswg;
• Mob plab zom mov, lom, haus dej cawv;
• Kev pub niam mis;
• Yam 1 ntshav qab zib.

Sab sij huam

Ua ntej siv, koj yuav tsum kawm txog cov kev mob tshwm sim thiab cov tsos mob txhawm rau qhia tus kws kho mob kom raws sijhawm txog lub cev qhov tshuaj tiv thaiv kom kho cov kev kho mob kom zoo. Ntawm cov feem ntau tsis yuav tshwm sim:

• Caj dab tsis zoo;
• Dyspeptic cuam tshuam;
• Mob taub hau zoo li mob taub hau;
• Kev tsis txaus siab ntawm cov lus sib dhos ntawm txoj hnyuv;
• Kab mob ua pa;
• Txo tsis zoo ntawm kev pw tsaug zog;
• Exacerbation ntawm pancreatitis thiab lwm txoj kev pathologies ntawm lub txiav;
• Kev o;
• Kev hnyav dua, anorexia;
• Cov kab mob pwm nyob rau ntawm daim tawv nqaij.

Qhov tshwm sim ntawm cov kev mob tshwm sim tuaj yeem kwv yees nyob rau WHO:

• Ntau zaus (> 1 / 0,1);
• Feem ntau (> 0.001, <0.1);
• Ncaj ncees (> 0.001, <0.01).

Cov ntaub ntawv ntawm cov ntawv kho mob tau nthuav tawm hauv lub rooj.

Yuav thov li cas

Cov lus sau ua ntej "tau ntsib" nyob rau hauv lub npe ntawm cov tshuaj qhia tau tias muaj cov metformin hauv nws cov muaj pes tsawg leeg, tab sis cov tshuaj no tau coj ib yam nkaus li thaum muab tshuaj Januvia, tshuaj raws li sitagliptin tsis muaj metformin.

Tus kws kho mob suav qhov ntau npaum li cas, thiab noj tshuaj thaum sawv ntxov thiab yav tsaus ntuj nrog zaub mov.

Hauv qee qhov xwm txheej, ib qho yuav tsum ceev faj heev hauv kev kho mob ntawm Yanumet.

1. Mob pob txha taub hau. Sitagliptin muaj peev xwm txhim kho nws cov tsos mob. Tus kws kho mob yuav tsum ceeb toom rau tus neeg mob: yog tias muaj mob hauv plab lossis sab xis hypochondrium, koj yuav tsum tsum tsis txhob noj tshuaj ntxiv.
2. Lactic acidosis. Qhov mob hnyav thiab tsis yog li no tsuas yog txaus ntshai nrog kev phom sij, thiab cov kev kho mob cuam tshuam thaum cov tsos mob tshwm sim. Nws tuaj yeem lees paub los ntawm kev ua pa luv, mob epigastric, ua daus no, hloov ntshav sib xyaw, nqaij pob txha tsis meej, asthenia, thiab lub plab zom mov.
3. Kev ntshav siab. Nyob rau hauv cov xwm txheej paub, tawm tsam keeb kwm ntawm Yanumet, nws tsis txhim kho. Nws tuaj yeem tsim kev npau taws los ntawm kev tawm dag zog ntau dhau, cov zaub mov tsis muaj calorie (txog 1000 kcal / hnub) khoom noj khoom haus, teeb meem nrog cov qog adrenal thiab lub caj pas pituitary, kev quav dej cawv, thiab kev siv β-blockers. Tsub qhov muaj feem ntau ntawm cov ntshav qog ntshav qab zib nyob rau hauv cov kev kho kom zoo nrog insulin.
4. Cov hlwv pathology. Kev pheej hmoo ntawm kev tsim mob lactic acidosis nce ntxiv nrog rau mob raum, yog li nws yog qhov tseem ceeb los saib xyuas creatinine. Qhov no yog qhov tseeb tshwj xeeb rau cov neeg mob ntshav qab zib, txij li lawv lub raum tsis ua haujlwm tej zaum yuav yog asymptomatic.
5. Kev ua haujlwm tsis zoo. Yog hais tias lub cev muaj kev tsis haum nrog cov kev tshwm sim ua xua, cov tshuaj raug muab tso tseg.
6. Kev phais mob. Yog tias tus mob ntshav qab zib muaj kev npaj ua haujlwm, ob hnub ua ntej nws, Janumet tau muab tso tseg thiab tus neeg mob pauv mus rau insulin.
7. Iodine-muaj cov khoom lag luam. Yog tias tus neeg sawv cev raws tshuaj iodine yog qhia nrog Yanumet, qhov no tuaj yeem ua rau mob raum.

Cov nyhuv ntawm Yanumet rau cov poj niam cev xeeb tub tau kawm tsuas yog rau cov neeg sawv cev ntawm lub ntiaj teb tsiaj. Hauv cov pojniam cev xeeb tub, kev loj hlob ntawm tus menyuam hauv plab tsis tau sau tseg thaum noj cov tshuaj metformin. Tab sis cov kev txiav txim siab no tsis txaus siv tshuaj kho mob rau cov poj niam cev xeeb tub. Hloov mus rau cov tshuaj insulin thaum kev npaj theem ntawm cev xeeb tub.

Metformin kuj dhau mus rau hauv niam cov kua mis, yog li ntawd, Yanumet tsis raug sau rau kev pub mis.

Metformin tsis cuam tshuam rau kev tsav tsheb lossis cov txheej txheem tsis yooj yim, thiab synagliptin tuaj yeem ua rau qaug zog thiab qaug zog, yog li ntawd, Januvia tsis siv yog tias muaj kev cuam tshuam sai thiab muaj qhov kub siab ntawm kev saib xyuas xav tau.

Qhov teeb meem ntawm kev overdose

Txhawm rau zam dhau kev tshaj tawm ntawm metformin, koj tuaj yeem siv tsis tas siv ntxiv rau Yanumet. Kev noj tshuaj ntau dhau yog txaus ntshai nrog cov kab mob lactic acidosis, tshwj xeeb tshaj yog nrog cov tshuaj tshaj ntawm metformin. Thaum cov tsos mob ntawm kev noj ntau dua tshwm sim, kev kho mob tshwm sim uas siv los ua kom tsis haum.

Vim li cas txhim kho Metformin complexes nrog Yanuvia, Galvus, Onglyza, Glybyuryd, yog tias koj tuaj yeem siv tib cov cuab yeej hauv cov kev kho mob sib cais sib cais? Cov kev sim pom tau hais tias nrog rau txhua txoj kev tswj hwm rau tus mob ntshav qab zib hom 2, Metformin kuj tseem nyob (txawm tias hloov mus rau insulin). Ntxiv mus, thaum siv ob qho tshuaj yeeb dej cawv nrog cov txheej txheem sib txawv ntawm kev ua, cov txiaj ntsig ntawm cov tshuaj tsub kom ntau ntxiv thiab koj tuaj yeem ua nrog cov tshuaj noj nrog cov tshuaj noj qis dua.

Nws tsuas yog ib qho tseem ceeb los tswj cov koob tshuaj ntawm cov tshuaj metformin hauv pob (500 mg, 850 mg lossis 1000 mg) txhawm rau kom zam dhau cov tsos mob ntau dhau. Rau cov neeg mob uas tsis nco qab haus txhua hom tshuaj noj raws sijhawm, sijhawm zoo yuav txhua yam lawv xav tau nyob rau ib lub sijhawm yog qhov txiaj ntsig zoo uas cuam tshuam loj rau kev nyab xeeb thiab cov txiaj ntsig ntawm kev kho mob.

Yeeb tshuaj sib cuam tshuam

Lub peev xwm ntawm metformin raug txo los ntawm diuretics, glucagon, corticosteroids, cov thyroid hormones, phenothiazines, qhov ncauj tshuaj tiv thaiv hauv cov ntsiav tshuaj, phenytoin, nicotinic acid, sympathomimetics, calcium antagonists, isoniazid. Hauv kev sim, ib koob tshuaj nifedipine ntau ntxiv kom nqus ntawm metformin hauv cov neeg tuaj noj qab haus huv hauv cov kev tshawb fawb, lub sijhawm nce mus txog qhov kawg thiab ib nrab ntawm lub neej tseem nyob li qub.

Cov cuab yeej hauv lub cev yuav ua kom muaj zog los ntawm insulin, tshuaj ntawm sulfonylurea pawg, acarbose, MAO thiab ACE inhibitors, NSAIDs, oxytetracycline, clofibrate derivatives, cyclophosphamide, β-blockers. Kev siv ib zaug ntawm furosemide los ntawm cov neeg noj qab nyob zoo hauv kev sim tau ntxiv kev nqus thiab faib cov tshuaj metformin los ntawm 22% thiab 15%, feem. Lub raum tshem tawm qhov tseem ceeb tsis tau hloov pauv ntau yam. Tsis muaj cov ntaub ntawv hais txog kev sib koom tes pab ntev nrog furosemide thiab metformin.

Cov tshuaj uas muab zais cia hauv cov tubules sib tua rau cov tshuab thauj, yog li siv sijhawm ntev lawv tuaj yeem nce qhov siab tshaj plaws ntawm metformin txog 60%.

Cimetidine inhibits qhov tsis pom kev ntawm metformin, kev txuam nrog cov tshuaj hauv cov ntshav tuaj yeem ua rau mob acidosis.

Yanumet tseem tsis sib xws nrog haus cawv, uas tseem yuav ua rau muaj kev muaj peev xwm acidosis.

Thaum kawm txog kev hloov tshuaj ntawm lwm pab pawg (metformin, simvastatin, glibenclamide, warfarin, rosiglitazone, tshuaj tiv thaiv), synagliptin tsis yog tshwj xeeb. Lub plasma concentration ntawm digoxin ntau ntxiv los ntawm 18% thaum noj tib lub sijhawm nrog sitagliptin.

Kev soj ntsuam ntawm qhov tshwm sim ntawm 858 cov neeg noj qab nyob zoo nyob rau hauv kev sim uas tau noj 83 hom tshuaj sib xyaw ua ke, 50% ntawm cov neeg ua haujlwm hauv lub raum, tsis tau sau ib qho tseem ceeb ntawm kev nqus thiab kev faib tawm ntawm sitagliptin.

Kev ntsuas thiab tus nqi

Yanumet yog cov tshuaj muaj nqi ntau: qhov nruab nrab, tus nqi hauv cov khw muag tshuaj muaj txiaj ntsig los ntawm ob thiab ib nrab txog peb txhiab rubles rau ib lub thawv nrog 1-7 cov paib (14 ntsiav tshuaj hauv ib lub hlwv). Lawv tsim cov tshuaj qub hauv Spain, Switzerland, Tebchaws Netherlands, Tebchaws Asmeskas, Puerto Rico. Ntawm cov analogues, tsuas yog Velmetia yog kiag li haum nyob rau hauv muaj pes tsawg leeg. Zoo sib xws hauv kev ua tau zoo thiab ATS code tshuaj:

• Douglimax;
• Glibomet;
• Txawv Tebchaws;
• Avandamet.

Glibomet suav nrog metformin thiab glibenclamide, uas muab nws lub peev xwm hypoglycemic thiab hypolipidemic.Kev qhia rau kev siv zoo ib yam li cov lus pom zoo rau Yanumet. Douglimax ua raws li metformin thiab glimepiride. Tus txheej txheem ntawm kev sib kis thiab ntsuas tau zoo ib yam li Yanumet. Tripride muaj cov tshuaj glimepiride thiab pioglitazone, uas muaj cov nyhuv tshuaj tua kab mob thiab cov cim zoo sib xws. Avandamet, uas yog kev sib xyaw ntawm metformin + rosiglitazone, kuj tseem muaj cov yam ntxwv hypoglycemic.

Yog Yanumet tsis haum

Cov laj thawj ntawm kev hloov cov tshuaj tuaj yeem sib txawv: rau qee yam, cov tshuaj tsuas yog tsis pab ua kom tau qib siab, rau lwm tus nws ua rau muaj kev mob tshwm sim tsis tu ncua lossis tsuas yog nws tsis tuaj yeem them taus.

Thaum kev siv cov tshuaj tsis tuaj yeem lav zoo rau cov piam thaj, nws raug hloov los ntawm cov tshuaj insulin. Lwm cov ntsiav tshuaj hauv qhov no tsis tau muaj txiaj ntsig. Yuav luag txhua zaus, los ntawm kev kho cov tshuaj tiv thaiv kev ntxhov siab, kev ua haujlwm txiav, thiab ua tiav hom kab mob ntshav qab zib hom 2 tau dhau mus rau hom ntshav qab zib hom 1.

Txawm tias cov ntsiav tshuaj niaj hnub no yuav ua rau tsis muaj txiaj ntsig yog tias koj tsis quav ntsej cov lus pom zoo ntawm tus neeg endocrinologist rau cov khoom noj uas tsis muaj carb thiab cov khoom siv thauj khoom.

Cov kev mob tshwm sim yog feem ntau npau taws los ntawm metformin, sitagliptin hauv qhov kev hwm no tsis muaj kev phom sij. Raws li nws cov peev txheej ntawm cov tshuaj, Metformin yog cov tshuaj tshwj xeeb, ua ntej koj nrhiav kev hloov rau nws, nws tsim nyog los ua qhov kev mob siab tshaj plaws kom yoog tau. Dyspeptic cuam tshuam yuav dhau sij hawm, thiab metformin yuav ua kom qab zib li qub tsis muaj kev rhuav tshem cov txiav thiab lub raum. Tsawg qhov tsis xav tau lub txiaj ntsig yog muab los ntawm kev noj Janumet tsis yog ua ntej lossis tom qab noj mov, tab sis thaum noj mov.

Txhawm rau txuag nyiaj, koj tuaj yeem hloov Janumet lossis Januvia nkaus xwb nrog cov ntshiab metformin. Hauv khw muag tshuaj network, nws yog qhov zoo dua los xaiv lub cim Glyukofazh lossis Siofor cov khoom lag luam hloov chaw ntawm cov chaw tsim khoom hauv tsev.

Tus mob ntshav qab zib thiab kws kho mob txog Yanumet

Hais txog cov tshuaj Janumet, kev tshuaj xyuas ntawm cov kws kho mob yog qhov sawv daws pom. Cov kws kho mob hais tias: ib qho tseem ceeb ntawm nws cov khoom siv (tshwj xeeb yog sitagliptin) yog qhov lawv tsis ua rau cov ntshav qog ntshav qab zib. Yog tias koj tsis ua txhaum txhaum txoj cai tswjfwm uas tau hais tseg thiab ua raws li cov lus pom zoo ntawm khoom noj khoom haus thiab kev qhia paub lub cev, cov ntsuas ntawm qhov ntsuas yuav tsawg tsawg. Yog tias muaj qhov tsis xis nyob hauv lub epigastrium thiab lwm yam tsis raug mob, qhov tsim nyog yuav tsum faib cov koob tshuaj txhua hnub rau 2 koob tshuaj txhawm rau txhawm rau txo lub nra ntawm lub cev. Tom qab hloov kho dua tshiab, koj tuaj yeem rov qab mus rau tsoomfwv yav dhau los, yog tias cov piam thaj ntau dua li cov txiaj ntsig pom, kev kho raws li cov kws kho mob tau pom zoo.

Txog Yanumet, tus neeg mob tshuaj xyuas yog qhov muaj kev sib cav, vim tias tus kab mob hauv txhua tus neeg tau nce mus txawv. Feem ntau ntawm tag nrho cov neeg mob cov neeg laus yws txog cov kev mob tshwm sim, vim tias ob lub raum, thiab lub cev tag nrho, twb yauv los ntawm cov kab mob sib xyaw.

Endocrinologist muaj cov lus tshaj tawm nrov: "Kev ua kis las thiab noj zaub mov noj - txhaj tshuaj tiv thaiv kab mob ntshav qab zib." Txhua tus neeg uas tshawb txog kev noj tshuaj zoo, thiab ntseeg hais tias cov tshuaj tshiab, lwm qhov kev txhawb nqa lossis tshuaj ntsuab yuav kho tus mob ntshav qab zib kom tsis tu ncua ntau, yuav tsum nco ntsoov nws ntau zaus.