COV PIAM THAJ THIAB DEJ CAWV: KEV SIB RAUG ZOO, KEV TSHUAJ XYUAS TUS NEEG MOB, COV TXIM

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Metformin muaj nyob rau hauv cov tshuaj uas nrov npe Glucophage. Nws yog thawj cov tshuaj uas tau tsim los kho hom 2 mob ntshav qab zib mellitus, tshwj xeeb hauv kev hnyav dua neeg.

Kuj tseem siv rau hauv kev kho mob ntawm polycystic ovary syndrome.

Tsuas muaj pov thawj tsawg txog kev muaj peev xwm ntawm metformin los tiv thaiv kev mob plawv ntawm lub siab txo cov ntshav qabzib. Cov neeg uas pib noj cov tshuaj no feem ntau muaj ntau lo lus nug txog kev noj ntau npaum li cas, kev mob tshwm sim, kev noj zaub mov, thiab kev cuam tshuam nrog lwm yam tshuaj yeeb dej caw.

Glucophage thiab cawv, piv txwv li, tsis sib xyaw nrog ib leeg, thaum noj lawv ib txhij nce kev pheej hmoo ntawm kev txhim kho hypoglycemic coma thiab cerebrovascular raug mob (ONMK).

Muaj pes tsawg leeg

Ib ntsiav tshuaj Glucofage muaj 500, 800 thiab 1000 mg ntawm metformin hydrochloride. Muaj nyob hauv cov hlwv ntawm 30 thiab 60 daim.

Mechanism ntawm kev ua

Cov tshuaj yeeb tshuaj tsis cuam tshuam rau kev tsim kho thiab muab cov kua dej tso pa tawm. Nws ua feem ntau los ntawm thaiv cov txheej txheem ntawm kev cais cov mob hepatic glycogen kom tso kua nplaum dawb.

Glucofage ntsiav tshuaj 1000 mg

Ua rau cov nqaij mos rhiab rau insulin (rog thiab leeg), txhawb txoj kev nkag ntawm carbohydrates rau hauv lub cell. Txij li nws inhibits qhov sib txuas ntawm triglycerides thiab inhibits qhov nqus ntawm fatty acids nyob rau hauv cov hnyuv, nws raug nquahu kom siv rau hauv cov neeg mob rog dhau. Nws qhov txiaj ntsig zoo ntawm kev siv rog hauv lub cev tau muab sau cia.

Nws noj ntawm qhov ncauj, kiag li nqus tsis pub dhau 60 feeb, qhov siab tshaj plaws ntshav plasma concentration tau txog tom qab 2, 5 teev. Ib nrab-lub neej yog 6.5 - 7.5 teev, uas qhia txog qhov yuav tsum tau siv tshuaj ntau zaus. Nws yog metabolized feem ntau hauv lub siab.

Cov Khoom Qhia

Qhov tseem ceeb tshaj plaws rau kev siv ntawm Glucophage yog nce qabzib kam thiab muaj ntshav qab zib hom 2.

Nrog rau qhov tsis muaj txiaj ntsig ntawm kev noj zaub mov zoo thiab kev hloov kho hauv lub neej, cov tshuaj tau muab tshuaj kho raws li kev kho mob monotherapy lossis hauv kev sib xyaw nrog lwm cov tshuaj uas muaj suab thaj, suav nrog insulin.

Nws tau tsim nws tus kheej los ua cov cuab yeej tiv thaiv kev txhim kho kev mob ntshav qab zib (micro thiab macroangiopathies).

Glucophage feem ntau tau noj los ntawm cov neeg noj qab haus huv (txawm tias ncaws pob) thiaj li yuav poob phaus. Xws li kev siv cov tshuaj yog qhov tsis tsim nyog thiab tuaj yeem ua rau ntau yam kev puas tsuaj ntawm cov metabolism.

Nkag Tawm Cov Cai

Glucophage yog noj ib ntsiav tshuaj 3 zaug hauv ib hnub, tom qab noj mov. Cov tshuaj yuav tsum tau muab ntim nrog ib khob ntawm dej ntshiab. Qhov pib koob tshuaj yog feem ntau 500 mg, nce ntxiv yog tias tsim nyog.

Cov Yuav Tsum Muaj

Glucophage yog yeeb tshuaj ntawm kev xaiv hauv cov neeg mob ntshav qab zib mellitus tawm tsam keeb kwm yav dhau los ntawm lub cev hnyav.

Ua ntej lub sij hawm teem tseg, tus kws kho mob endocrinologist muaj lub luag haujlwm kom paub txog tus neeg mob nrog rau cov kev sib txuas hauv qab no:

keeb kwm kev tsis haum tshuaj rau metformin (anaphylaxis, urticaria, Quincke edema);
hnub nyoog txog 10 xyoo;
daim siab ua haujlwm ntawm ntau lub hauv paus;
kev quav cawv;
congestive plawv nres;
mob raum tsis ua haujlwm (lub davhlau ya nyob twg);
mob ketoacidosis.

Ua ntej siv cov tshuaj, ntau txoj kev tshawb nrhiav thiab kuaj cov khoom siv yuav tsum tau ua los txiav txim siab lub xeev kev ua haujlwm ntawm lub siab thiab lub raum. Nrog lub suab nrov txo qis hauv kev tswj hwm ntawm glomerular, kev hloov kho koob tshuaj yog tsim nyog.

Sab sij huam

Tawm tsam keeb kwm yav dhau los ntawm kev noj tshuaj Glucofage, kev phiv tshuaj tuaj yeem tshwm sim uas feem ntau ua rau kev hloov pauv ntawm cov tshuaj:

saj kev ua txhaum;
lub plab zom mov hauv daim ntawv ntawm tsam plab, mob plab, raws plab, ntuav;
megaloblastic anemia;
daim tawv nqaij xoo pob;
hypoglycemic coma;
lactic acidosis.

Yog tias cov tsos mob saum toj no tshwm sim, sab laj nrog tus kws kho mob tam sim ntawd.

Kuv puas tuaj yeem sib xyaw nrog cawv?

Koj yuav tsum paub txog kev muaj peev xwm tsim cov kev mob tshwm sim hauv kev sib cuam tshuam ntawm cov tshuaj uas koj tau noj. Glucophage thiab cawv yuav ua rau muaj kev pheej hmoo ntawm qhov tshwm sim tsis tshwm sim. Qhov phom sij loj tshaj plaws yog kev siv cawv ib txhij ntawm cov cawv thaum kho nrog metformin.

Muaj teeb meem phom sij rau lub neej xam nrog rau:

ntshav qogCov. Haus cawv thaum noj Metformin provokes ib tug ntse txo nyob rau hauv cov ntshav qab zib. Clinically, tus mob no yog pom los ntawm kev tsis meej pem, tshee hnyo ntawm ob txhais tes, tawm hws. Qhov no yog vim muaj qhov tseeb tias ntau cov piam thaj tau noj thaum lub cev metabolism ntawm ethyl haus cawv. Yog tias koj ntxiv rau qhov no lub peev xwm ntawm metformin los tiv thaiv kev rhuav tshem ntawm glycogen hauv daim siab, koj yuav tau txais kev ua kom zoo rau kev mob ntshav qab zib. Yog tias koj tsis tuaj yeem zam haus dej haus cawv ntau me me (hauv kev lom zem nrog cov phooj ywg zoo siab), ceeb toom rau lwm tus tias koj noj tshuaj Glucophage, qhia lawv txog cov tshwm sim muaj cov ntshav qab zib tsawg, piav qhia lawv yuav pab tau li cas;
lactic acidosisCov. Qhov no yog qhov tsis tshua muaj, tab sis muaj peev xwm muaj kev phom sij hauv lub neej uas nthuav dav thaum metformin ua ke nrog cawv. Cov lactic acid (lactate) yog ib qho khoom siv hauv qab ntawm cov metabolism hauv qabzib, uas tau siv los ntawm ntau cov ntaub so ntswg ua qhov chaw ntawm lub zog. Tawm tsam keeb kwm yav dhau los ntawm kev noj Glucofage, lub cev pib tsim cov tshuaj ntau dua li niaj zaus, cawv kuj txhawb nws cov synthesis. Yog li, cov lactate ntau dhau los ua rau lub raum, lub ntsws, lub siab, thiab lub leeg ntshav, ua rau lub hlwb puas. Cov tsos mob tshwm sim ntawm cov kab mob lactic acid feem ntau yog qhov tsis muaj zog, qhov ncauj qhuav, kiv taub hau, mob nqaij nrawm, mob ib ce, ua tsis taus pa, xeev siab thiab ntuav.

Kev mob hypoglycemia thiab lactic acidosis xav tau kev kho mob kub ceev hauv tsev kho mob tshwj xeeb. Yog tias koj hnov cov tsos mob no thaum noj cov tshuaj metformin thiab haus cawv, koj yuav tsum hu rau lub tsheb thauj neeg mob tam sim ntawd.

Txawm hais tias metformin thiab cawv ua rau tsis muaj qhov cuam tshuam, qhov no tsis txhais tau tias dej cawv yuav tsum tso tseg txhua yam. Hauv cov ntawv nyeem txawv teb chaws muaj lub tswvyim ntawm "haus dej", lus "ib haus", uas muaj 14 grams cawv dawb. Yog li, nws yog ib qho tseem ceeb kom them nyiaj rau lub zog ntawm dej haus.

Piv txwv li, "ib qho haus dej" yuav yog 350 ml ntawm npias (5% cawv), 140 ml ntawm cov cawv qaug, 40 ml ntawm cov vodka zoo tib yam.

Cov kws tshawb fawb pom zoo tias cov poj niam tsis siv ntau dua ib koob tshuaj ib hnub, thiab cov txiv neej tsis pub dhau ob.

Koj yuav tsum ua raws li cov cai thawj ntawm lub tsiab peb caug: tsis txhob haus cawv rau ntawm lub plab khoob, tsis txhob haus dej cawv nrog cov ntshav qabzib hauv cov ntshav, haus dej txaus, ib txwm kuaj qib qab zib ua ntej haus cov dej muaj zog.

Ntev npaum li cas yog cov tshuaj tawm los ntawm lub cev?

Cov tshuaj muaj lub luv luv ib nrab-lub neej, tsuas yog 6,5 teev.

Qhov no txhais tau hais tias tom qab lub sijhawm no lub siab nyob rau hauv cov ntshav ntshav yuav raug txo los ntawm ib nrab. Qhov tsawg kawg nkaus koob tshuaj, uas muaj kev kho kom haum thiab ua rau muaj kev tsis haum siab, yog kwv yees li 5 ib nrab ntawm lub neej.

Qhov no txhais tau hais tias Glucofage raug tshem tawm tag nrho hauv lub cev tom qab 32 teev. Cov tshuaj raug pov tseg los ntawm hepatic enzymes, kwv yees li 30% yog tshem tawm tsis pauv nrog tsiaj quav.

Xyuas

Anastasia: “Ib qho tshuaj tau zoo nyob rau theem pib ntawm tus mob ntshav qab zib hom 2, tom qab ib hlis siv tas li, ntshav qabzib poob los ntawm 7.5 mmol / L txog 5 mmol / L. Tus kws kho mob pom zoo txuas ntxiv chav kawm ib xyoo. ”

Vitaliy: “Kuv pom zoo kom noj ntshav qabzib tsuas yog mob ntshav qab zib, thiab tsis yog ua rau poob phaus. Kuv noj 850 mg 3 zaug ib hnub tom qab noj mov, Kuv zoo siab heev. Txaus siab nrog tus nqi, 60 ntsiav tshuaj tuaj yeem yuav rau 100 rubles. "

Natalya: "Nws coj Glucofage rau polycystic ovary, tau txais txiaj ntsig zoo thiab poob 7 phaus rau ib hlis. Kuv kom nws rau kuv cov phooj ywg. Thaum xub thawj kuv tsis ntseeg tias qhov nws ua tau zoo, tab sis sijhawm dhau los kuv paub tias qhov zais cia rau qhov ua tiav yog tau txais thiab ua raws nraim li cov lus qhia ntawm tus kws kho mob tuaj koom. "