Gliclazide MV: lus piav qhia ntawm cov tshuaj, tshuaj xyuas ntawm kev siv, tus nqi

Gliclazide MB yog hypoglycemic qhov ncauj npaj ntsig txog sulfonylurea derivatives ntawm 2 tiam. Cov tshuaj:

1. txhawb kev tsim tawm ntawm cov tshuaj hormone insulin;
2. txhim kho cov nyhuv insulin-secretory li ntawm cov piam thaj;
3. lowers ntshav qab zib;
4. nce insulin rhiab heev nyob rau hauv peripheral cov ntaub so ntswg.;
5. normalizes qib ntawm kev yoo glycemia;
6. txo qis tsim cov piam thaj los ntawm daim siab;
7. ntxiv rau kev cuam tshuam rau cov metabolism hauv carbohydrate, cov tshuaj txhim kho microcirculation.

Glyclazide txo txoj kev pheej hmoo ntawm cov ntshav txhaws hauv cov hlab ntsha me me, cuam tshuam ib txhij ob lub tshuab uas koom nrog kev txhim kho kev mob ntshav qab zib mellitus:

• ib nrab inhibition ntawm platelet adhesion thiab aggregation;
• rau kev rov ua haujlwm;
• kom txo cov platelet ua kom muaj lwm yam (thromboxane B_2, beta-thromboglobulin).

Cov lus qhia rau kev siv thiab cim

Gliclazide xyaw nrog kev kho kev noj zaub mov noj tau muaj txiaj ntsig rau tus mob ntshav qab zib hom 2, yog tias kev noj haus thiab kev tawm dag zog tsis tau tshwm sim zoo.

Cov Yuav Tsum Muaj

• ntshav qab zib hom 1;
• siab rhiab heev rau Glyclazide lossis rau cov tshuaj tiv thaiv (rau sulfonamides, rau sulfonylurea derivatives);
• cev xeeb tub thiab lactation;
• mob hepatic los sis lub raum tsis ua haujlwm;
• noj miconazole;
• mob dias taub;
• kuaj mob ntshav qab zib;
• mob ketoacidosis;
• hnub nyoog txog 18 xyoo;
• lactase tsis txaus;
• kev tsis haum xeeb lactose;
• piam thaj-galactose malabsorption Tus kws kho mob tsis pom zoo kom siv cov tshuaj ua ke nrog rau danazol lossis phenylbutazone.

Thaum twg mam nrog ceev faj

Gliclazide tuaj yeem siv tsis tau daim ntawv kho mob, vim tias cov tshuaj tsis haum rau txhua tus. Ntawm no yog daim ntawv teev cov xwm txheej uas nws yuav tsum siv nrog ceev faj:

1. Noj tsis txaus thiab tsis xwm yeem;
2. hnub nyoog siab heev;
3. hypothyroidism;
4. pituitary lossis adrenal tsis txaus ntseeg;
5. cov kab mob hnyav heev ntawm cov hlab plawv (atherosclerosis, mob hlab plawv);
6. kev ua haujlwm hypopituitarism;
7. ntev glucocorticosteroid kho;
8. mob siab los yog lub raum tsis ua haujlwm;
9. piam thaj-6-phosphate dehydrogenase tsis muaj peev xwm;
10. quav cawv.

Ua tib zoo mloog! Cov tshuaj tsuas yog kho rau cov laus!

Yuav noj li cas lub sijhawm cev xeeb tub thiab pub niam mis

Tsis muaj cov ntaub ntawv hais txog kev siv cov tshuaj thaum lub sijhawm cev xeeb tub. Cov ntaub ntawv hais txog kev siv lwm cov sulfonylurea derivatives thaum cev xeeb tub yog qhov tsawg.

Hauv kev kawm tshawb fawb txog tsiaj, teratogenic cov teebmeem ntawm cov tshuaj tsis pom. Txhawm rau txo txoj kev pheej hmoo ntawm kev yug menyuam, koj xav tau kev tswj kom meej meej cov ntshav qab zib mellitus (txoj kev kho tsim nyog).

Tseem Ceeb! Kev siv tshuaj hypoglycemic qhov ncauj thaum cev xeeb tub tsis tau sau tseg. Rau kev kho mob ntshav qab zib thaum cev xeeb tub, cov tshuaj insulin raug xaiv. Txais tos ntawm cov tshuaj hypoglycemic yog pom zoo kom hloov nrog tshuaj insulin.

Ntxiv mus, txoj cai no siv tau rau hauv rooj plaub thaum cev xeeb tub tshwm sim thaum lub sijhawm noj tshuaj, thiab yog tias cev xeeb tub tsuas muaj nyob hauv cov phiaj xwm ntawm tus poj niam.

Muab qhov tseeb tias tsis muaj cov ntaub ntawv hais txog kev noj tshuaj rau hauv niam cov kua mis, qhov kev pheej hmoo ntawm kev txhim kho me nyuam hauv plab tsis tuaj yeem tsis suav nrog. Raws li, kev siv Gliclazide thaum pub mis niam yog contraindicated.

Cov lus qhia thiab tsuas tshuaj

30 mg hloov-tso tawm ntsiav tshuaj yuav tsum noj 1 zaug hauv ib hnub thaum noj tshais. Yog tias tus neeg mob tau txais kev kho mob no thawj zaug, thawj zaug yuav tsum yog 30 mg, qhov no kuj siv tau rau tib neeg uas muaj hnub nyoog 65 xyoos. Maj mam hloov cov tshuaj kom txog thaum tsim nyog kho kom tshwm sim.

Kev xaiv koob tshuaj yog pom zoo nyob ntawm theem ntawm cov piam thaj hauv cov ntshav tom qab pib kev kho mob. Ib qho kev pauv hloov pauv ntxiv tuaj yeem nqa tawm tsuas yog tom qab ob lub lim tiam.

Glyclazide MB tuaj yeem hloov nrog Glyclazide ntsiav tshuaj nrog kev tso tawm (80 mg) hauv ib hnub ib zaug ntawm 1-4 pieces. Yog tias rau qee qhov laj thawj tus neeg mob tsis siv tshuaj, cov tshuaj ntxiv yuav tsum tsis txhob siab dua.

Yog tias Glyclazide MB 30 mg ntsiav tshuaj siv los hloov lwm cov tshuaj hypoglycemic, lub sijhawm hloov pauv tsis tas yuav tsum muaj nyob rau hauv cov ntaub ntawv no. Nws tsuas yog tsim nyog los ua kom tiav txhua hnub ntawm qhov kev noj tshuaj dhau los thiab tsuas yog ib hnub tom ntej noj Gliclazide MB.

Tseem Ceeb! Yog tias tus neeg mob tau raug kho yav dhau los nrog sulfonylureas nrog lub neej ib nrab ntev, ua tib zoo saib xyuas cov ntshav qabzib concentration yog qhov tsim nyog rau 2 lub lis piam.

Qhov no yog qhov tsim nyog nyob rau hauv kev txiav txim kom tsis txhob muaj kev txhim kho hypoglycemia, uas yuav tshwm sim tiv thaiv cov keeb kwm yav dhau los ntawm cov khoom seem ntawm cov kev kho mob dhau los.

Cov tshuaj tuaj yeem ua ke nrog alpha-glucosidase inhibitors, biguanides lossis insulin. Cov neeg mob uas lub raum tsis ua haujlwm me me lossis mob raum tsis ua haujlwm, Gliclazide MB tau muab tshuaj rau tib lub sijhawm li cov neeg mob uas lub raum ua haujlwm zoo. Cov tshuaj yog contraindicated nyob rau hauv kev mob raum tsis ua haujlwm.

Cov neeg mob yuav muaj kev pheej hmoo ntshav siab ntshav qab zib

Cov neeg mob yog cov muaj pheej hmoo ua tus mob hypoglycemia:

1. nrog ntsuas tsis tau lossis noj tsis tau;
2. nrog kev ua haujlwm tsis zoo los yog mob endocrine tsis zoo (hypothyroidism, adrenal thiab pituitary tsis txaus);
3. nrog rau kev tshem tawm cov kab mob hypoglycemic tom qab lawv siv ntev;
4. nrog cov ntawv txaus ntshai ntawm cov hlab plawv pathologies (feem ntau atherosclerosis, carotid arteriosclerosis, mob hlab plawv);

Rau cov neeg mob zoo li no, cov tshuaj Glyclazide MB yog cov tshuaj kho mob tsawg kawg (30 mg).

Sab sij huam

Cov tshuaj tuaj yeem ua rau mob glycemia, uas yog pom los ntawm cov tsos mob hauv qab no:

• kev xav ntawm kev tshaib plab;
• kev qaug zog, ua haujlwm tsis muaj zog;
• mob taub hau, kiv taub hau;
• nce hws, tshee, paresis;
• arrhythmia, palpitations, bradycardia;
• nce ntshav siab;
• insomnia, tsaug zog;
• kev chim siab, ntxhov siab, ntxhov siab, kev ntxhov siab;
• kev ntxhov siab;
• tsis hnov ​​qab ntawm kev saib xyuas;
• cov tshuaj tiv thaiv qeeb thiab tsis muaj peev xwm mloog zoo;
• kev hnov ​​txawv txav;
• pom kev tsis zoo;
• aphasia;
• poob ntawm kev tswj tus kheej;
• zoo nkaus li tsis paub pab;
• pa ua tsis taus pa;
• cramps
• delirium;
• tsis nco qab, tsis nco qab lawm.

Kev tsis haum tshuaj:

1. erythema;
2. daim tawv nqaij xoo pob;
3. urticaria;
4. khaus ntawm daim tawv nqaij.

Muaj cov kev mob tshwm sim los ntawm cov hnyuv:

• mob plab;
• cem quav;
• xeev siab, ntuav
• tsis tshua muaj cholestatic jaundice muaj tus kab mob siab, tab sis lawv yuav tsum tau tshem tawm cov tshuaj tam sim ntawd.

Siv ntau dhau thiab kev sib cuam tshuam

Nrog rau qhov ntau npaum li cas ntawm kev noj tshuaj, qhov ntxim nyiam ntawm kev txhim kho kev mob ntshav qab zib siab ntau, uas tej zaum yuav muaj cov leeg hlab ntsha tsis sib haum, mob nriaj, tsis nco qab, siab. Thaum pom thawj cov tsos mob no, tus neeg mob yuav tsum tau mus pw hauv tsev kho mob sai.

Yog tias qhov mob ntshav qab zib tsis tsaug zog yog qhov xav tau lossis kuaj pom, 40-50% kev daws teeb meem yog muab tshuaj rau tus neeg mob. Tom qab ntawd, lawv tso ib lub ncos nrog rau 5% dextrose tov, uas yog qhov tsim nyog los tswj kev ib txwm ua ntawm cov piam thaj hauv cov ntshav.

Tom qab tus neeg mob rov qab nco qab, kom tsis txhob rov qab qog ntshav qab zib, nws yuav tsum tau muab cov zaub mov muaj nplua nuj nyob hauv kev zom cov zaub mov kom yooj yim. Qhov no yuav tsum yog ua tib zoo saib xyuas cov ntshav qab zib kom tsawg thiab kev tshuaj xyuas tus neeg mob tas li 48 teev.

Cov kev nqis tes ua ntxiv, nyob ntawm tus mob ntawm tus neeg mob, txiav txim siab los ntawm tus kws kho mob uas tuaj koom. Vim tias cov lus cog lus ntawm cov tshuaj rau plasma protein, lim ntshav yog qhov tsis muaj txiaj ntsig.

Glyclazide ua rau kom muaj txiaj ntsig ntawm cov tshuaj anticoagulants (warfarin), tsuas yog cov xwm txheej yog tias koj yuav tsum tau kho cov tshuaj ntawm lub tshuaj anticoagulant.

Danazole nrog rau Gliclazide yog qhov ua rau mob ntshav qab zib. Ob qho tib si thaum siv cov danazol thiab tom qab nws rho tawm, tswj cov kua nplaum thiab koob tshuaj glycazide yuav tsum ua haujlwm.

Cov kev tswj hwm ntawm kev tswj hwm ntawm phenylbutazone ua rau lub ntsej muag hypoglycemic ntawm Gliclazide (nws txo qis kev tawm ntawm lub cev, hloov chaw los ntawm kev sib txuas lus nrog cov ntshav protein). Glyclazide koob tshuaj xyuas thiab kuaj ntshav qabzib yuav tsum muaj. Ob qho tib si thaum lub sijhawm noj phenylbutazone, thiab tom qab nws tshem tawm.

Nrog cov kab ke tswj hwm ntawm Miconazole thiab thaum siv lub ntsej muag gel hauv lub qhov ncauj kab noj hniav, nws ua kom cov nyhuv hypoglycemic ntawm cov tshuaj, mus txog rau kev txhim kho tsis nco qab.

Ethanol thiab nws cov derivatives txhim kho ntshav qab zib kom tsawg, tuaj yeem ua rau kev txhim kho hypoglycemic coma.

Thaum siv ua ke nrog lwm cov tshuaj hypoglycemic (biguanides, acarbose, insulin), fluconazole, beta-blockers, H2-histamine receptor blockers (cimetidine), angiotensin-hloov mus rau enzyme inhibitors (enalapril, captoprilamide antioxidants, tsis-steroidal sulfide inhibitors thiab hypoglycemic effect, ntsig txog, qhov pheej hmoo ntawm hypoglycemia.

Chlorpromazine hauv koob tshuaj ntau dua (ntau tshaj 100 mg / hnub) nce qhov siab ntxiv ntawm cov piam thaj hauv cov ntshav, inhibiting kev zais ntawm cov tshuaj insulin. Ob qho tib si thaum siv cov tshuaj chlorpromazine, thiab tom qab nws tshem tawm, tswj cov piam thaj thiab ib qho kev hloov pauv hauv Glyclazide yog qhov yuav tsum tau ua.

GCS (kho lub cev, sab nraud, sab hauv, kev siv hauv lub cev) nce ntshav qab zib nrog kev txhim kho ntawm ketoacidosis. Ob qho tib si thaum siv GCS thiab tom qab lawv rho tawm, tswj ntshav qabzib thiab qhov hloov pauv ntawm cov tshuaj Gliclazide yog qhov yuav tsum tau ua.

Terbutaline salbutamol, ritodrin ua ke - nce ntshav qab zib. Tswj ntshav qabzib nyob rau hauv cov hlab ntshav yog yuav tsum tau ua thiab, yog tias tsim nyog, hloov mus rau kev kho mob insulin.

Cov lus qhia tshwj xeeb thiab daim foos tso tawm

Cov tshuaj Gliclazide MB muaj txiaj ntsig tsuas yog ua ke nrog kev noj zaub mov kom muaj calorie tsawg, uas muaj cov roj carbohydrates me me. Kev ntsuam xyuas cov piam thaj tsis tu ncua, ob qho ntawm lub plab khoob thiab tom qab noj mov, yuav tsum tau kuaj xyuas. Qhov no yog qhov tshwj xeeb tshaj plaws nyob rau theem pib ntawm kev kho.

Thaum kho nrog cov tshuaj, txhawm rau kom tsis txhob raug mob thiab raug mob ntawm txoj kev, nws raug nquahu kom tsis txhob tsav tsheb thiab ua haujlwm nrog cov phom sij phom sij uas xav tau kev kub siab ntawm kev mloog thiab cov tshuaj tiv thaiv sai.

30 mg ntsiav tshuaj, ntim hauv hlwv ntawm 10 daim.

Lub txee lub neej ntawm Gliclazide yog 3 xyoos, tom qab uas nws tsis tuaj yeem siv. Cov tshuaj yuav tsum muab cia rau hauv qhov chaw qhuav, tsaus thiab txias, ua rau cov menyuam yaus siv tsis tau.

Hauv thaj tsam sib txawv ntawm lub teb chaws, tus nqi ntawm ib qho tshuaj txawv ntawm 120 txog 150 rubles. Peb tab tom tham txog cov pob khoom uas muaj 60 ntsiav tshuaj. Muaj ntawv ntim hauv cov kaus poom polymer. Ib lub thawv lossis 1 mus rau 6 lub hlwv muab tso rau hauv lub thawv ntawv thawv.

Qhov sib txawv ntawm tus nqi yog nyob ntawm ntau yam: cov chaw tsim khoom, cheeb tsam, chaw muag tshuaj.