VOZULIM - COV LUS QHIA RAU KEV SIV, NQE, XYUAS THIAB ANALOGUES

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Qhov no yog tib neeg cov kua dej tsim los ntawm kev tsim kho tshuab. Nws raug siv los kho hom 1 lossis 2 mob ntshav qab zib.

Lub Npe Tsis Yog Neeg Tsis Muaj Npe

Tib neeg cov tshuaj ntxuav hluav taws xob.

Vozulim yog tib neeg cov insulin tsim los ntawm kev tsim kho caj ces, siv los kho ntshav qab zib hom 1 lossis hom 2.

ATX

A10AB01.

Tso cov ntawv thiab cov nyob ua ke

Muaj nyob rau hauv daim ntawv ntawm kev daws rau kev txhaj tshuaj (tshem tawm rau kev tswj hwm ntawm subcutaneous). 1 ml muaj 100 IU ntawm cov tshuaj nquag ntawm insulin. Hauv lub raj mis - 10 ml ntawm kev daws. Hauv ib rab koob xau pov tseg - 3 ml ntawm ib qho kev daws hauv cartridge.

Pharmacological kev txiav txim

Nws yog hypoglycemic tus neeg sawv cev ntawm nruab nrab ntev. Nws yog txhua yam zoo li tib neeg insulin, txawm hais tias nws tau tsim los ntawm kev tsim caj ces. Nws cuam tshuam nrog receptors ntawm sab nraud cell daim nyias nyias thiab ua ib qho chaw ruaj khov nrog lawv.

Txhim kho qhov sib xyaw ntawm cyclic AMP hauv cov rog thiab nplooj siab. Nws tuaj yeem nkag mus rau hauv cov leeg nqaij. Nws txhim kho kev tsim pyruvate kinase, hexokinase, glycogen synthetase ntawm qib intracellular.

Vim tias kev ua haujlwm ntawm cov txheej txheem hauv cov kua nplaum ntev, qhov taw qhia ntawm cov khoom no hauv cov ntshav txo. Stimulates tsim cov rog, glycogen, protein. Txo tus nqi ntawm cov piam thaj tsim nyob rau hauv daim siab mob nqaij.

Feem ntau ntawm cov tshuaj metabolites ntawm cov tshuaj tau tawm ntawm lub raum.

Cov Tshuaj Pharmacokinetics

Qhov pib ntawm kev ua ntawm cov khoom no yog nyob ntawm tus qauv (s / c lossis IM) thiab thaj chaw txhaj tshuaj, nrog rau qhov ntim ntawm cov tshuaj txhaj. Nws yog qhov tsis sib luag hauv cov ntaub so ntswg, nws tsis kis thoob plaws qhov chaw ntawm lub plab thiab nkag mus rau niam mis.

Kev tiv thaiv kab mob tshwm sim nrog kev pab ntawm enzyme insulinase hauv ob lub raum thiab nplooj siab. Feem ntau ntawm cov tshuaj metabolites yog ua tawm los ntawm lub raum.

Kev ntsuas rau siv

Qhia rau kev kho mob:

insulin-hom mob ntshav qab zib hom 1;
yam 2 mob ntshav qab zib mellitus;
dag tsis tu ncua ntawm lub cev kom txo qis cov tshuaj noj hauv qhov ncauj, nrog rau kev tawm tsam ib nrab rau lawv, muab cov kev kho nyuaj ua nrog;
intercurrent kab mob.

Cov Yuav Tsum Muaj

Cov tshuaj yog contraindicated nyob rau hauv hypoglycemia. Tsis pom zoo rau ntau lub cev rhiab rau insulin thiab lwm yam khoom ntawm kev daws.

Yuav noj Vulim li cas?

Subcutaneously, txog ib nrab ib teev ua ntej noj tshais. Qhov chaw txhaj tshuaj yuav tsum tau hloov txhua lub sijhawm. Hauv qee kis tshwj xeeb, kev tswj hwm intramuscular yog raug kho. Nws yog nruj me ntsis txwv tsis pub txhaj tshuaj rau ntawm Vozulim.

Vozulim yog siv subcutaneously, txog ib nrab ib teev ua ntej noj tshais.

Qhov hloov ntawm tus neeg mob mus rau lwm lub insulin yog nrog tswj tus nqi ntawm cov piam thaj hauv cov ntshav.

Feem ntau cov kev mob tshwm sim ntawm kev tswj hwm insulin yog hypoglycemia.

Cov koob tshuaj tau xaiv tsuas yog tus kheej, noj rau hauv tus account lub yam ntxwv ntawm lub cev thiab insulin xav tau. Tawm tswv yim 8-24 ib hnub.

Yog tias qhov koob tau dhau 0.6 PIECES rau hauv ib phaus ntawm qhov hnyav, tom qab ntawd koj yuav tsum laim 2 qhov kev txhaj tshuaj rau ntau qhov chaw ntawm lub cev. Yog tias cov neeg mob tau txais ntau dua 100 IU ntawm cov tshuaj insulin, tom qab ntawd thaum hloov pauv, koj yuav tsum tau mus pw hauv tsev kho mob. Hloov mus rau lwm lub kua dej yog nrog kev tswj hwm ntawm cov ntshav piam thaj hauv cov ntshav.

Phiv los ntawm Vozulima

Feem ntau cov kev mob tshwm sim ntawm kev tswj hwm insulin yog hypoglycemia. Tsis zoo li hyperglycemia, nws muaj kev tsim dheev, thiab nws cov tsos mob nce sai. Cov neeg mob txhawj xeeb:

nce hws;
palpitations
pallor ntawm daim tawv nqaij;
mob taub hau heev;
tsis meej pem;
npaws
trembling ntiv tes;
zoo nkaus ntawm loog hauv lub ntsej muag;
txoj kev xav tob ntawm kev tshaib plab;
dhia hauv ntshav siab.

Yog hais tias tus neeg mob tsis tau txais kev pab, ces kev txo ntshav qab zib tsuas yuav ua kom tsaus ntuj. Kev mob ntshav qab zib siab kawg nkaus ua rau kev txhim kho tsis nco qab.

Anaphylactoid thiab lwm cov kev tsis haum yog qhov tsis tshua muaj. Ntawm cov kev tawm tsam hauv zos - mob thiab o ntawm thaj chaw txhaj tshuaj, o. Kev siv ntev ntev ua rau muaj qhov tshwm sim ntawm lipodystrophy.

Cov kev mob tshwm sim los ntawm cov tshuaj suav nrog mus ntshav siab.

Vozulim yuav ua rau tawm hws.

Thaum lub sij hawm kho cov tshuaj, nce siab rau lub siab.

Tom qab siv cov tshuaj, ib qho mob taub hau feem ntau tshwm sim, uas yog qhov cuam tshuam ntawm kev phiv.

Kev mob ntshav qab zib siab kawg nkaus ua rau kev txhim kho tsis nco qab.

Tawm tsam keeb kwm ntawm kev noj tshuaj, tsis meej pem yuav tshwm sim.

Kev noj tshuaj yuav tuaj yeem nrog los ntawm cov ntiv tes tshee.

Lwm cov kev phiv suav nrog kev hloov me me thiab sij hawm hloov chaw hauv kev rov ua haujlwm. Qhov no yog qhov tshwj xeeb tshaj yog thaum pib ntawm txoj kev kho.

Cuam tshuam rau lub peev xwm los tswj cov tshuab

Vim hais tias hypoglycemia yog ua tau, tom qab ntawd cov neeg muaj kev txhim kho rau cov xwm txheej zoo li no yuav tsum tsis kam tsav tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj.

Cov lus qhia tshwj xeeb

Tsuas tshuaj yog ib txwm xaiv nrog ceev faj rau cov neeg mob uas muaj mob loj heev cov ntshav khiav tsis zoo thiab ischemic pathologies.

Kev hloov koob tshuaj yog qhov tsim nyog rau kis kab mob, lub qog ua haujlwm ntawm lub qog ua haujlwm (Addison's disease), dys- lossis hypopituitarism, mob raum tsis ua haujlwm, mob qog. Nrog cov pathologies li no, nws yog ib qho tsim nyog yuav tau ua cov kev ntsuam xyuas mob raws sij hawm.

Kev muaj ntshav qab zib tsawg tshwm sim nrog kev siv tshuaj ntau dhau, insulin, ntuav, raws plab, ua kom lub cev tawm mus. Qee lub sij hawm txawm tias hloov qhov chaw txhaj tshuaj yuav ua rau cov suab thaj hauv cov ntshav qab zib tsawg dua.

Noj tshuaj tsis zoo hauv cov neeg mob uas muaj ntshav qab zib hom 1 ua rau kev loj hlob ntawm hyperglycemia. Nws yog qhov ua rau nqhis dej, xeev siab, syncope, tsis ploj, thiab ntws los ntawm daim tawv nqaij. Los ntawm cov neeg mob tuaj cuag tus ntxhiab tsw ntxhiab ntawm acetone. Hyperglycemia tuaj yeem ua rau tuag taus ketoacidosis.

Hyperglycemia tuaj yeem ua rau tuag taus ketoacidosis.

Vozulima kev hloov kho koob tshuaj yog qhov tsim nyog rau mob raum tsis ua haujlwm.

Ntuav yuav ua tau kom txo qis cov ntshav qab zib.

Hauv cov kab mob ntawm cov thyroid caj pas, nws yog ib qho tsim nyog yuav tau kho lub koob tshuaj ntawm cov tshuaj.

Kev ua rau lub cev ntau dua ua rau cov neeg mob ntshav qab zib tsawg.

Cov neeg mob uas muaj hnub nyoog 65 xyoos yuav tsum ua tib zoo xaiv qhov ntau npaum ntawm cov tshuaj.

Cov menyuam yaus tsis raug txwv tsis pub xaiv Wozulim.

Siv rau lub sijhawm qub

Cov neeg mob uas laus dua 65 xyoo yuav tsum xaiv cov koob tshuaj zoo thiab saib xyuas kev noj qab haus huv lub sijhawm kho.

Txiag tej menyuam

Cov me nyuam tsis tau txwv tsis pub sau ntawv rau noj cov tshuaj no. Thaum siv tshuaj kho mob, kev noj qab haus huv thiab glycemia tshuaj xyuas tas li.

Siv thaum cev xeeb tub thiab lactation

Kev siv cov insulin no raug tso cai yog tias tus neeg mob cev xeeb tub. Nws yog ib qho tsim nyog yuav tsum tau coj mus rau hauv qhov kev hloov pauv hauv kev xav tau ntawm insulin thaum lub sijhawm sib txawv ntawm cov lus piav qhia: kev txo qis ntawm thawj lub hlis thiab nce me ntsis hauv lwm lub sijhawm. Qhov xav tau nws poob ua ntej yug tus kheej thiab tom qab yug tus menyuam.

Thaum lub sij hawm pub mis niam, tus poj niam yuav tsum tau pom kev rau ntau lub hlis, nws yog qhov tsim nyog kom ua tiav kev ruaj khov ntawm qhov xav tau ntawm insulin.

Daim ntawv thov rau lub raum khiav tsis zoo

Nrog lub raum pathologies, lub cev xav tau cov tshuaj insulin tuaj yeem hloov pauv.

Siv rau lub siab ua haujlwm tsis zoo

Nrog daim siab pathologies, kev txo qis hauv lub cev xav tau cov tshuaj hormones yog qhov ua tau. Yog tias koj txuas ntxiv prick nws nyob rau hauv tib lub koob tshuaj, ces tus neeg mob tej zaum yuav muaj mob hypoglycemia heev, tig mus rau hauv lub tsis nco qab lawm.

Noj ntau dhau ntawm Vozulim

Nrog kev siv tshuaj ntau dhau, mob ntshav qab zib ntshav qab zib. Kev loj hlob sai ntawm qhov tshwm sim no yog yam ntxwv. Qee zaum tus neeg mob tuaj yeem yuav tsis nco qab nyob hauv ob peb feeb.

Kev siv Vozulima raug tso cai yog tias tus neeg mob cev xeeb tub.

Tus neeg mob yuav tsum nqa cov piam thaj nyob rau hauv yog tias nws xav tias thawj cov cim ntawm kev poob qis hauv qab zib.

Nrog rau kev txhim kho hypoglycemic coma, ib qho tshuaj dextrose yog muab tshuaj rau tus neeg mob.

Txhua tus neeg mob ntshav qab zib tau qhia txog cov kev pheej hmoo ntawm kev mob hypoglycemia thiab thawj cov cim qhia ntawm nws txoj kev loj hlob. Nws yuav tsum nqa cov piam thaj hauv tsam yog nws hnov cov cim ntawm kev poob qab zib.

Mob ntshav qab zib siab yuav kho tau hauv tsev kho mob. Yog hais tias tus neeg mob nco qab yog khaws cia, ces dextrose muab rau nws (hais tawm, subcutaneously, intramuscularly lossis intravenously). Glucagon txhaj tshuaj yog tsim. Nrog rau kev txhim kho ntawm lub qog hypoglycemic, qhov kev daws teeb meem dextrose yog txhaj rau dav hlau thiab tso dej hiav txwv. Lub sijhawm tiv thaiv ntawm kev qhia yog kom txog thaum tus neeg rov qab nco qab.

Kev cuam tshuam nrog lwm yam tshuaj

Kev txo lub plawv hypoglycemic thaum ua ke nrog qee cov tshuaj tuaj yeem nce lossis poob.

Qhov sib zog ntawm kev nqis tes ua yog los ntawm:

cov tshuaj sulfa;
MAO, ACE inhibitors;
derivatives ntawm salicylic acid;
tshuaj steriods;
Bromocriptine;
tetracycline tshuaj tua kab mob;
Ketoconazole;
Clofibrate;
Fenfluramine;
Pyridoxine;
Quinidine;
Quinine thiab Chloroquinine;
tag nrho cov kev npaj muaj ethanol.

Nrog kev sib xyaw ntawm Ketoconazole thiab Vozulima, qhov ua kom lub ntsej muag hypoglycemic ntawm lub tom kawg nce.

Morphine txo cov nyhuv hypoglycemic ntawm Vozulim.

Nicotine txo qis cov nyhuv hypoglycemic ntawm insulin.

Txo cov nyhuv ntawm:

Glucagon;
Kev loj hlob hormone;
txhua yam kev tiv thaiv kab mob hauv qhov ncauj;
voj thiab thiazide diuretics;
Bromocriptine;
heparin;
npaj - calcium tubule antagonists;
morphine;
Diazoxide.

Cov neeg haus luam yeeb yuav tsum nco ntsoov tias nicotine ua rau lub ntsej muag tsis haum ntawm insulin. Thiazolidinediones ua rau muaj kev cuam tshuam ntawm cov hlwb rau cov tshuaj insulin.

Cawv tau zoo

Cov neeg mob tau txais cov tshuaj insulin muaj qhov txo qis ethanol ntau. Cawv cawv provokes kev txhim kho ntawm cov qog ntshav qab zib.

Analogs

Biosulin;
Gansulin;
Gensulin;
Insuman;
Kev pov hwm;
Protafan;
Rinsulin;
Humulin;
Cwj mem Royal;
Cia txoj cai 30 70.

Vim li cas thiab thaum twg cov kws kho mob tau sau ntawv tshuaj insulin?

Cov ntsiab lus ntawm lub tsev muag tshuaj tawm

Nws yog tso tawm los ntawm cov tshuaj noj.

Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?

Tsis yog.

Nqi

Tus nqi ntawm ib lub raj mis 10 ml yog li 600 rubles. Tus nqi ntawm rab koob xev hluav taws xob yog kwv yees 990 rubles.

Cia rau cov neeg mob rau cov tshuaj

Cov tshuaj yuav tsum tau muab cia rau hauv qhov chaw txias (ntsuas kub - ntawm +2 txog + 8ºC). Lub raj mis qhib los yog cov kua xaum xaum yog cia hauv qhov chaw sov. Lawv yuav tsum siv nyob rau hauv 4 lub lis piam.

Hnub tas sij hawm

Cov tshuaj yeeb yaj kiab yog qhov tsim nyog rau siv hauv 2 xyoos txij li hnub ntawm kev tsim khoom. Nws yog qhov txwv tsis pub thov tom qab lub sijhawm no.

Chaw tsim tshuaj paus

Nws yog tsim nyob rau hauv kev lag luam Wokhard Yees, Bandra Kurla Complex, Bandra (Sab Hnub Tuaj), Mumbai.

Humulin muaj cov nyhuv zoo sib xws ntawm lub cev.

Ib qho muaj sib xyaw zoo li yog Biosulin.

Rinsulin yog cov tshuaj zoo sib xws.

Koj tuaj yeem hloov cov tshuaj ntawm cov tshuaj xws li Protafan.

Xyuas

Irina, hnub nyoog 35 xyoo, Moscow: "Qhov no yog insulin, uas pab ua kom cov piam thaj tsis tu ncua. Cov insulins dhau los ua rau muaj ntshav qab zib tsawg, qee zaum tsis pom kev zoo. Tej zaum hno ntawm Uzulim tsis ua rau muaj kev mob tshwm sim, o ntawm thaj chaw txhaj tshuaj. Nrog rau cov insulin no thiab kev noj zaub mov zoo tswj hwm kev tswj hwm cov piam thaj thiab tsis pub tshaj 6 mmol. "

Pavel, 55 xyoo, Nizhny Novgorod: "Cov tshuaj no zoo txo qhov muaj zog ntawm cov piam thaj thiab tsis pub nws cia li dhau lawm. Cov tshuaj yav dhau los tsis muab qhov tshwm sim zoo li no. Kuv txoj kev noj qab haus huv tau zoo dua, thiab tsis tau muaj suab thaj rau hauv qab zib rau ntau lub hlis. Kuv pom tias tam sim no kuv nce me ntsis. "Kuv tseem ua raws li kev noj haus thiab kev noj haus txhua hnub, yog li kuv cov piam thaj tsis hla."

Natalia, 49 xyoo, St. Petersburg: "Kuv muaj ntshav qab zib hom 1, kuv yuav tsum tau txhaj tshuaj insulin tas li. Qee yam tshuaj ua rau kuv muaj ntshav qab zib tsawg, uas qee zaus nyuaj rau tsis tuaj yeem. Vim muaj Vulizim, Kuv tswj kom muaj suab thaj, kuv txoj kev noj qab haus huv zoo dua tuaj. nws muaj peev xwm tswj hwm kev mob ntshav qab zib thiab tiv thaiv kev txhim kho mob hnyav. "

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