Kev siv Ofloxin yog qhov tsim nyog rau tus lej thiab cov kabmob ua rau muaj kev cuam tshuam ntau yam hauv lub cev. Cov tshuaj muaj qhov dav dav ntawm kev txiav txim, tab sis muaj contraindications thiab ua rau muaj kev phiv, yog li ntawd, ua ntej pib txoj kev kho, koj yuav tsum sab laj nrog koj tus kws kho mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Ofloxacin.
Kev siv Ofloxin yog qhov tsim nyog rau tus lej thiab cov kabmob ua rau muaj kev cuam tshuam ntau yam hauv lub cev.
ATX
J01MA01. Cov tshuaj yog hais txog cov tshuaj tua kab mob ntawm cov kab ke ua haujlwm, cov neeg mob ntawm quinolone.
Tso cov ntawv thiab cov nyob ua ke
Muaj 2 daim ntawv ntawm Ofloxin muaj nyob rau ntawm cov chaw lag luam kws tshuaj: cov ntsiav tshuaj thiab kev txhaj tshuaj. Hauv thawj kis, cov tshuaj muaj nyob hauv 2 koob tshuaj. Chav ntsuas cov tshuaj tua kab mob muaj 200 mg lossis 400 mg ntawm lub cev tseem ceeb tshuaj ofloxacin.
Cov ntsiav tshuaj dawb coated nrog zaj duab xis txheej muaj qhov biconvex round puab, ntawm ib sab tes sib cais los ntawm ib qho kev ceeb toom, thiab ntawm lwm qhov kev txua yog thov taw qhia qhov ntau npaum. Hauv daim ntawv tshuaj no ntau npaum li cas, cov tshuaj muaj nyob rau hauv cov hlwv ntim tso rau hauv thawv ntawv thawv.
Kev daws rau kev txhaj tshuaj yog cov kua ntshiab nrog dej daj. Cov tshuaj raug muag hauv 100 ml iav vials, txhua qhov ntawm nws muaj 200 mg ofloxacin.
Cov ntsiav tshuaj dawb coated nrog zaj duab xis txheej muaj qhov biconvex round puab, ntawm ib sab tes sib cais los ntawm ib qho kev ceeb toom, thiab ntawm lwm qhov kev txua yog thov taw qhia qhov ntau npaum.
Pharmacological kev txiav txim
Cov tshuaj tua kab mob yog koom nrog koob tshuaj fluoroquinolone thiab muaj ntau qhov pom ntawm kev ua los tiv thaiv cov kab mob gram-positive thiab gram-negative aerobic. Ofloxin cov haujlwm tau tshwm sim los ntawm cov kab mob me me xws li:
- Escherichia coli;
- Salmonella;
- Shigella;
- Proteus;
- Morganella morganii;
- Klebsiella;
- Enterobacter;
- Citrobacter
- Haemophilus mob npaws;
- Neisseria gonorrhoeae;
- Neisseria meningitidis;
- Mycoplasma spp .;
- Chlamydia spp .;
- Dab Tsi Staphylococcus;
- Streptococcus.
Tus ua hauj lwm antibacterial tsis siv rau cov kab mob anaerobic. Cov khoom sib xyaw ua ke ntawm Ofloxacin nkag mus rau qhov ua kom pom tseeb ntawm qhov mob, thaiv qhov kev sib txuas ntawm DNA gyrase, uas yog qhov tsim nyog rau kev ua haujlwm li qub ntawm cov hlwb ntawm cov kab mob. Txwv txoj kev loj hlob, kev txhim kho thiab rov tsim tawm ntawm cov kab mob.
Cov nquag ua ke ntawm Ofloxin nkag mus rau hauv kev tsom mus rau ntawm o, thaiv qhov hluavtaws ntawm DNA gyrase.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog nqus sai thiab nrog cov ntshav nkag mus rau ntau yam plab hnyuv siab raum thiab cov ntaub so ntswg. Qhov siab tshaj plaws ntawm cov tshuaj nquag tau tshawb pom 60 feeb tom qab kev tswj hwm. Cov tshuaj tua kab mob tau muab faib rau hauv lub ntsws, mob ntsws sab sauv, kab mob ntawm lub plab, cov nqaij ntawm lub raum thiab qhov chaw mos, tsib lub zais zis, tawv nqaij thiab pob txha. Ofloxin muaj qhov theem siab ntawm kev ua haujlwm hauv cov dej hauv lub cev.
25% ntawm cov sib txuas uas tsim cov tshuaj tua kab mob thiab ua cov haujlwm kho ua kom cov plasma protein. Cov tshuaj no yog 80% nyob rau hauv cov zis hauv ib daim ntawv hloov pauv. Qhov no tshwm sim ib hnub tom qab kev tswj hwm. Qee qhov, cov tshuaj raug tshem tawm los ntawm txoj hnyuv. Ib nrab-lub neej ntawm kev siv tshuaj tiv thaiv yog 6 teev. Hauv cov neeg tsis muaj tswv yim creatinine tsawg, qhov luv no nce mus rau 13,5 teev.
Cov tshuaj yog nqus sai thiab nrog cov ntshav nkag mus rau ntau yam plab hnyuv siab raum thiab cov ntaub so ntswg.
Kev ntsuas rau siv
Cov tshuaj tau ua pov thawj ua tau zoo nyob rau hauv kev sib txuas ntau tus naj npawb ntawm kev kis mob thiab mob tshwm sim los ntawm cov kab mob microflora uas ntxim rau Ofloxin. Kev qhia rau kev siv tshuaj tua kab mob yog:
- cov kab mob mob hnyav ntawm cov pa txhauv sab sauv thiab mob ntsws (mob ntsws thiab mob ntsws ntev, mob ntsws);
- cov txheej txheem mob hauv cov txheej txheem ENT kabmob (sinusitis, otitis media, sinusitis, pharyngitis, laryngitis);
- kis kab mob ntawm txoj hnyuv thiab hauv txoj hnyuv (tshwj tsis yog cov kab mob enteritis);
- qhov txhab ntawm daim tawv nqaij, pob qij txha thiab pob txha;
- kab mob ntawm lub raum thiab mob txeeb zig (pyelonephritis, cystitis, mob tso zis);
- o cov qog prostate;
- kis kab mob ntawm cov kab mob deev (orchitis, colpitis, gonorrhea, chlamydia);
- mob rau daim npluag qhwv
- cov kab mob kev puas tsuaj rau lub qhov muag;
- kev tiv thaiv kev mob ntawm kev phais mob hauv kev phais mob;
- ntau yam kab mob hauv cov neeg uas raug tshuaj tiv thaiv kab mob;
- tham txog kev ua kom mob ntsws qhuav.
Cov tshuaj tua kab mob yog tshuaj los ntawm tus kws kho mob tom qab kuaj xyuas tus neeg mob thiab txiav txim siab qhov rhiab ntawm cov neeg kis tau tus mob mus rau cov tshuaj.
Cov Yuav Tsum Muaj
Cev xeeb tub thiab lactation yog ib qho kev tawm tsam. Cov tshuaj yog txwv nrog cov tib neeg tsis kam rau cov yeeb tshuaj uas ua rau muaj pes tsawg leeg, nrog rau kev nkag siab ntau ntxiv rau cov tshuaj fluoroquinolones.
Tsis txhob siv cov tshuaj rau hauv cov neeg mob uas muaj piam thaj-6-phosphate dehydrogenase tsis txaus. Cov tshuaj yog qhov txaus ntshai rau cov neeg uas tau mob hlab ntsha tawg lossis muaj keeb kwm ntawm CNS pathologies uas txo qis qhov qaug dab peg. Epilepsy yog nyob rau hauv daim ntawv ntawm contraindications. Tsis siv tshuaj tua kab mob rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Nrog saib xyuas
Nrog cov organic txhab ntawm lub hauv nruab nrab lub paj hlwb thiab lub raum pathologies loj, nws yog qhov zoo dua los muab kev nyiam rau lwm cov tshuaj. Cov tshuaj yog kws kho nrog ceev faj rau cov neeg kev txom nyem los ntawm cerebral arteriosclerosis thiab lwm yam kab mob cuam tshuam nrog kev ncig tsis xwm yeem.
Hauv cov mob raum loj pathologies, nws yog qhov zoo dua los muab kev nyiam rau lwm cov tshuaj.
Yuav ua li cas noj Ofloxin
Qhov ntau npaum li cas, kev tswj hwm thiab lub sijhawm ntawm kev kho mob yog txiav txim los ntawm tus kws kho mob raws li cov txiaj ntsig ntawm kev tshuaj ntsuam ntawm tus neeg mob, nws lub hnub nyoog thiab cov ntaub ntawv ntawm cov kab mob cuam tshuam. Cov ntsiav tshuaj yuav tsum tau nqos yam tsis muaj ntxo nrog cov dej ntau. Kev daws rau Txoj kev lis ntshav yog muab cov tshuaj dej los ntawm txau.
Rau qhov mob tsis yooj yim ntawm qhov mob txeeb zig, 100 mg ofloxacin yuav tsum noj 1-2 zaug nyob rau ib hnub. Nrog cov pyelonephritis thiab cov txheej txheem ua paug hauv chaw mos, 100-200 mg tau sau tseg nyob rau ncua sijhawm ob zaug ib hnub.
Cov kab mob ua rau lub cev ua pa, nrog rau kis mob rau pob ntseg, caj pas thiab lub qhov ntswg, pathologies ntawm cov ntaub so ntswg mos thiab txheej sab saud ntawm daim tawv nqaij, pob txha thiab pob qij txha tau raug kho nrog Ofloxin, siv 200 mg 2 zaug ib hnub. Hauv qhov muaj mob loj heev ntawm tus kabmob, 400 mg ntawm cov tshuaj tua kab mob raug tso cai ob zaug ib hnub.
Nrog kev puas tsuaj rau lub plab thiab kab mob sib kis, tus neeg mob tau kho tib txoj kev.
Txhawm rau tiv thaiv kev txhim kho kev kis mob hauv cov neeg uas muaj tshuaj tiv thaiv kab mob, kis tau tus mob. Rau qhov no, 200 mg ofloxacin yuav tsum tov nrog 5% piam thaj tov. Lub sijhawm tiv thaiv ntawm kev nqus ntshav yog 30 feeb.
Yog tias tus neeg mob muaj keeb kwm muaj mob raum lossis mob siab, cov lus qhia tau qhia tias txo tshuaj ntau npaum li cas.
Nrog ntshav qab zib
Ntawm cov ntshav qab zib, kev tshuaj xyuas cov ntshav qabzib hauv lub cev yog qhov tsim nyog, txij li thaum ua ke nrog Ofloxin thiab cov tshuaj uas tswj cov piam thaj hauv qab zib, ntshav qab zib yuav tshwm sim.
Thaum twg tsis koob tshuaj
Yog tias tus neeg mob tsis tau siv tshuaj tua kab mob thaum lub sijhawm tsim nyog, koj yuav tsum haus dej haus tshuaj tam sim ntawd thaum pom cov tshuaj uas ploj lawm.
Yog tias tus neeg mob tsis tau siv tshuaj tua kab mob thaum lub sijhawm tsim nyog, koj yuav tsum haus dej haus tshuaj tam sim ntawd thaum pom cov tshuaj uas ploj lawm.
Sab sij huam
Thaum kho nrog fluoroquinolone series, muaj ntau yam kev tsis zoo ntawm lub cev tshwm sim.
Kev kho mob txoj hnyuv
Hauv cov neeg mob thaum siv tshuaj tua kab mob, xeev siab, ntuav, raws plab, lossis cem quav yuav tshwm sim. Mob plab mob hauv plab tsis yog ib txoj cai tswj hwm. Qee tus neeg mob yws ntawm lub tiaj tus, kub siab, thiab lub qhov ncauj qhuav. Tsawg tsawg zaus, los ntshav tshwm sim ntawm cov khoom noj hauv lub plab zom mov, muaj qhov nce ntxiv ntawm kev ua haujlwm ntawm hepatic transaminases, kab mob siab thiab mob cholestatic daj ntseg, pseudomembranous enterocolitis muaj kev loj hlob.
Hematopoietic plab hnyuv siab raum
Qhov kev txiav txim ntawm cov tshuaj tua kab mob ua rau muaj qhov hloov pauv ntawm cov kab ke ntawm cov ntshav, ua rau ntshav tsis txaus, agranulocytosis, thrombocytopenia. Tej zaum los ntshav. Cov kev xav tsis zoo ntawm cov txheej txheem hematopoiesis ntawm cov pob txha pob txha tsis tshua pom muaj txiaj ntsig, kev nce qib hauv lub sijhawm prothrombin tshwm sim.
Nruab nrab hauv lub paj hlwb
Hauv qee tus neeg mob, kev tawm tsam hnyav los ntawm lub hauv nruab nrab ntawm cov leeg hlwb tsis tau txiav txim. Cov tib neeg yws yws txog kiv taub hau thiab mob taub hau, ua txhaum ntawm saj thiab hnov ntxhiab, lawv hnov zoo li tsis meej pem, lawv muaj kev txhawj xeeb ntau. Kev ntxhov siab, kev xav tua tus kheej, phobia, paranoia tsis raug cais tawm. Nyob rau hauv cov mob loj, convulsions, kev xav hnov dab tsi, kab ntsig, kev hnov lus tsis zoo thiab kev sib koom tes yog qhov ua tau.
Raws li kev phiv, teeb meem nrog lub hauv nruab nrab cov hlab leeg tsis tau txiav txim.
Los ntawm cov leeg musculoskeletal
Txais ntawm cov tshuaj tua kab mob fluoroquinolone tuaj yeem ua rau myasthenia gravis, mob caj dab, txha caj qaum. Cov leeg mob tsis muaj zog thiab kev txhim kho ntawm myalgia tau sau tseg.
Los ntawm lub tshuab ua pa
Cov kev xav tsis zoo tshwm sim hauv daim ntawv hnoos. Qee tus neeg mob muaj mob hauv lub qhov ntswg. Tsawg tsawg zaus, mob ntsws thiab hnoos qeev yog ua tau.
Ntawm ib sab ntawm daim tawv nqaij
Txoj kev txhim kho ntawm photosensitization tsis kav. Cov tshuaj tua kab mob tuaj yeem ua rau kom tawv nqaij ntau ntxiv thiab ua rau tawv nqaij ua pob.
Los ntawm genitourinary system
Cov tshuaj ua rau dysuria thiab hematuria, nephritis, lub raum pob zeb, ncua lossis nce tso zis. Mob thiab tawm pob hauv thaj tsam urogenital, vaginitis, candidiasis tsis raug cais tawm.
Los ntawm cov hlab plawv system
Thaum noj cov tshuaj, tachycardia tuaj yeem txhim kho, tej zaum yuav muaj kev nce siab lossis txo qis cov ntshav siab. Muaj qee zaus, mob ntsws o thiab mob plawv yuav tshwm sim.
Thaum noj tshuaj, teeb meem nrog lub plawv mob tuaj yeem tsim muaj ...
Endocrine system
Cov tshuaj ua rau lub cev tsis txaus siab metabolic. Cov neeg mob nco ntsoov nqhis dej, poob ceeb thawj. Hauv cov neeg mob ntshav qab zib, qhov nce siab los yog txo qis hauv cov ntshav qab zib cov ntshav yog tau (thaum noj cov tshuaj uas tsim nyog). Hauv ntshav dej, kev nce qib hauv cov roj cholesterol, TG thiab poov tshuaj tuaj yeem pom.
Kev ua xua
Ib qho kev phiv tshuaj ntawm cov tshuaj tiv thaiv yog urticaria, pruritus, thiab tawm pob. Mob pob txha caj qaum, ntau yam erythema, angioedema, anaphylactic shock tsis tshua pom.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj muaj qhov cuam tshuam tsis zoo rau kev tsav tsheb thiab lwm yam kev qhia nyuaj ntawm cov txuj ci, vim nws ua rau txo qis kev puas siab puas siab ntsws thiab ua rau cov tsis tuaj yeem tshwm sim los ntawm lub hauv nruab nrab lub paj hlwb.
Cov tshuaj muaj qhov cuam tshuam tsis zoo rau kev tsav tsheb thiab lwm yam kev qhia nyuab.
Cov lus qhia tshwj xeeb
Muaj cov xwm txheej nyob rau hauv uas cov tshuaj txwv tsis pub lossis txwv hnyav.
Siv thaum cev xeeb tub thiab lactation
Lub cev sib txuas ua ke hla tus nyom qhov tso tawm thiab raug nthuav tawm hauv niam cov kua mis. Cov tshuaj yeeb dej caw ua rau muaj qhov tsis zoo ntawm cov menyuam yaus. Yog li, thaum cev xeeb tub thiab thaum pub niam mis, koj siv tsis tau cov tshuaj tua kab mob. Thaum lub sijhawm lactation, yog tias tsim nyog, ib chav kawm ntawm txoj kev kho hauv leej niam ntawm tus menyuam yuav tsum pauv mus rau khoom noj khoom haus dag.
Khaws Ofloxinum rau cov menyuam yaus
Cov tshuaj yog contraindicated rau hauv cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Siv rau lub sijhawm qub
Thaum kho cov neeg mob lub hnub nyoog tiav, nws yog qhov yuav tsum tau soj ntsuam cov cim tseem ceeb tas li. Feem ntau, txoj kev kho kom haum yog pom zoo, vim muaj kev pheej hmoo ntawm kev puas tsuaj rau daim siab, lub raum thiab cov leeg hauv cov neeg laus.
Thaum kho cov neeg mob lub hnub nyoog tiav, nws yog qhov yuav tsum tau soj ntsuam cov cim tseem ceeb tas li.
Daim ntawv thov rau lub raum khiav tsis zoo
Nrog rau qhov tsis muaj creatinine tshem tawm, qhov dej ntim txhua hnub ntawm cov tshuaj tua kab mob yog txo qis. Kev kho mob nrog fluoroquinolone rau lub raum pathologies yog nyob rau hauv kev saib xyuas ntawm cov kws tshwj xeeb.
Siv rau lub siab ua haujlwm tsis zoo
Hauv cov kab mob siab mob siab, cov tshuaj yog kho nrog ceev faj.
Noj ntau dhau
Yog tias cov lus pom zoo ntawm cov tshuaj yog dhau, ntuav, kiv taub hau, cuam tshuam kev ua haujlwm ntawm kev txav, tsis meej pem thiab tsis pom kev. Tsis muaj ib qho tshuaj tua kab mob tshwj xeeb. Thaum noj ntau qhov tshuaj tua kab mob, kho plab zom mov tau ua tiav. Tom qab ntawd nqa tawm kev kho mob.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj tiv thaiv kab mob ntau ntxiv theophylline concentration hauv cov ntshav. Cov tshuaj tiv thaiv kab mob thiab kev npaj ua muaj magnesium, calcium, potassium thiab hlau txo qhov nqus ntawm Ofloxin, vim li no cov tshuaj no yuav tsum noj tom qab 2 teev.
Cov tshuaj nonsteroidal anti-inflammatory provoke kev ua txhaum cai thaum muaj kev sib txig sib luag nrog cov tshuaj fluoroquinolones. Glucocorticosteroids ua rau kom muaj kev pheej hmoo ntawm nqaij leeg. Cov tshuaj tiv thaiv kab mob tau siv nrog kev ceev faj hauv kev sib xyaw nrog cov tshuaj hypoglycemic. Qhov kev sib xyaw ua ke no tuaj yeem ua rau cov ntshav qabzib ntev dua.
Methotrexate thiab lub voj diuretics ua rau muaj kev lom ntau ntxiv ntawm ofloxacin. Thaum noj ua ke nrog cov tshuaj tiv thaiv tsis tau, muaj kev pheej hmoo los ntshav.
Cawv tau zoo
Lub sijhawm tshuaj tua kab mob, koj tsis tuaj yeem haus cawv. Cawv nce siab txog qhov tshwm sim ntawm cov kev mob tshwm sim thiab txo qhov uas siv tshuaj.
Analogs
Cov qauv tshuaj tiv thaiv cov tshuaj rau cov tshuaj tivthaiv loj yog cov tshuaj xws li Ofloxacin, Ofloks, Glaufloks, Taritsir, Uniflox. Cov tshuaj tua kab mob tuaj yeem yog cov tshuaj los ntawm pawg fluoroquinolones: Nolitsin, Norfloxacin, Levofloxacin, Glevo.
Ofloxin lub Tsev Muag Tshuaj Cov Sij Hawm So
Cov ntsiav tshuaj thiab Txoj kev lis ntshav daws tau faib los ntawm cov khw muag tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Ib qho tshuaj tua kab mob raug muag thaum muab cov tshuaj uas muaj ntawv pov thawj los ntawm kws kho mob pom zoo.
Ofloxin Nqe
Tus nqi ntawm cov tshuaj yog nyob ntawm qhov ntau thiab cov ntim. Tus nqi nyob ntawm 160 txog 280 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj yuav tsum muab cia kom deb ntawm qhov ncav cuag ntawm cov menyuam yaus ntawm chav tsev kub. Raug ntawm lub teeb thiab noo noo yuav tsum txwv.
Hnub tas sij hawm
Cov tshuaj yuav tsum tau siv nyob rau hauv 3 xyoos txij li hnub ntawm kev tsim khoom.
Ofloxin Chaw tsim tshuaj paus
Cov tshuaj yog tsim hauv Czech koom pheej los ntawm Zentiva A.C.
Cov tshuaj yuav tsum tau siv nyob rau hauv 3 xyoos txij li hnub ntawm kev tsim khoom.
Ofloxine Kev txheeb xyuas
Cov tshuaj tua kab mob tau txais ntau cov tshuaj xyuas.
Cov kws kho mob
Igor Vetrov, urologist, Minsk
Ofloxin yog cov tshuaj tua kab mob zoo, nws yog qhov zoo dua los mus sau nws tsuas yog mob hnyav. Rau cov mob me mus rau mob nyhav, siv cov tshuaj tsawg dua tuaj yeem siv.
Irina Rozanova, kws kho mob otolaryngologist, Volgograd
Cov tshuaj yog qhov zoo, tab sis yuav tsum muaj keeb kwm meej thiab xaiv txoj kev ntau npaum.
Cov neeg mob
Angelina, 27 xyoo, Michurinsk
Tom qab mob khaub thuas, mob ntsws pib. Ofloxin tau raug sau tseg. Qhov kub poob hauv ib hnub. Qhov hnoos tau li 3 hnub. Tab sis tam sim no kuv tsis tuaj yeem tshem ntawm dysbiosis thiab thrush.
Anton, 34 xyoo, Yaroslavl
Droppers nrog cov tshuaj tua kab mob no tau txais kev cawmdim los ntawm kev mob ntsws. Nws nyob hauv tsev khomob tau 10 hnub.Cov kev mob tshwm sim yog tsis txaus siab, tab sis koj tuaj yeem muaj sia nyob nrog kev ntxhov siab kom tau txais ntawm koj ob txhais taw.
