Atomax hais txog cov tshuaj-statins ntawm III tiam, uas muaj cov lipid-txo cov nyhuv. Nws yog qhov sib tw xaiv cov khoom thaiv ntawm HMG-CoA reductase, ib qho enzyme uas ua rau muaj kev txwv ntawm cov roj ntsha ua ke thaum ntxov.
Kev siv cov tshuaj muaj feem cuam tshuam rau hauv kev kho mob ntawm hypercholisterinemia thiab nce qib thyroglobulin (TG). Ua tsaug rau Atomax, lipid metabolism tuaj yeem ua tau zoo li qub thiab muaj kev cuam tshuam loj heev ntawm cov roj cholesterol siab tuaj yeem tiv thaiv tau.
Hauv cov ntaub ntawv no koj tuaj yeem nrhiav cov ncauj lus kom ntxaws txog cov tshuaj Atomax, cov lus qhia rau kev siv, tus nqi, tus neeg mob tshuaj xyuas thiab cov tshuaj zoo sib xws.
Tso tawm daim ntawv thiab muaj pes tsawg leeg
Atomax yog ib cov tshuaj uas tsom rau HMG-CoA reductase, uas ua rau cov roj cholesterol ua ke tsis txaus nyob rau hauv lub siab ua haujlwm. Tsis zoo li statins ntawm thawj tiam, Atomax yog tshuaj ntawm cov khoom siv hluavtaws.
Ntawm kev lag luam pharmacological koj tuaj yeem nrhiav cov tshuaj tsim los ntawm lub tuam txhab Indian HeteroDrags Limited thiab cov nroj tsuag hauv tsev ntawm Nizhpharm OJSC, Skopinsky Pharmaceutical Plant LLC.
Atomax yog muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb uas puag ncig lub cev nrog convex sab. Los ntawm saum toj no lawv yog them nrog ib zaj duab xis daim nyias nyias. Ib pob muaj 30 ntsiav tshuaj.
Cov ntsiav tshuaj suav nrog 10 lossis 20 mg ntawm cov tshuaj nquag - atorvastatin calcium trihydrate.
Ntxiv nrog rau lub ntsiab tivthaiv, txhua ntsiav tshuaj thiab nws lub plhaub muaj qee qhov nqi:
- croscarmellose sodium;
- purified talcum hmoov;
- lactose dawb;
- magnesium stearate;
- pob kws nplej siab;
- calcium carbonate;
- povidone;
- silicon dioxide anhydrous colloidal;
- crospovidone;
- triacetin;
Ntxiv rau, qee qhov nqi ntawm titanium dioxide nyob hauv qhov npaj.
Tus txheej txheem ntawm kev txiav txim ntawm cov tshuaj nquag
Raws li tau hais ua ntej, lipid-txo cov nyhuv ntawm Atomax tau tiav los ntawm thaiv HMG-CoA reductase. Lub hom phiaj tseem ceeb ntawm cov enzyme no yog los hloov cov methylglutarylcoenzyme A rau mevalonic acid, uas yog qhov ua ntej ntawm cov roj (cholesterol).
Atorvastatin ua rau lub siab ua haujlwm, txo qis ntawm LDL thiab cov roj cholesterol. Nws siv tau zoo los ntawm cov neeg mob kev txom nyem los ntawm homozygous hypercholesterolemia, uas tsis tuaj yeem kho nrog lwm cov tshuaj uas txo cov roj cholesterol. Lub zog ntawm qhov txo qis hauv cov roj (cholesterol) ncaj qha nyob ntawm qhov koob tshuaj ntawm cov khoom tseem ceeb.
Atomax tsis pom zoo kom noj thaum noj mov, li kev noj mov txo tus nqi ntawm kev nqus. Cov nquag ua haujlwm yog txig nqus hauv cov hnyuv. Cov ntsiab lus siab tshaj plaws ntawm atorvastatin raug pom 2 teev tom qab thov.
Nyob hauv kev cuam tshuam ntawm cov enzymes tshwj xeeb CY thiab CYP3A4, cov metabolism tshwm sim hauv cov nplooj siab, vim tias cov tshuaj parahydroxylated tau tsim. Tom qab ntawd cov metabolites raug tshem tawm ntawm lub cev nrog rau cov kua tsib.
Kev taw qhia thiab contraindications rau kev siv tshuaj
Atomax yog siv los txo cov roj (cholesterol). Tus kws kho mob sau ntawv muab tshuaj rau hauv cov tshuaj nrog kev noj zaub mov kom zoo rau kev kuaj mob raws li thawj, kab mob siab rau tsev neeg thiab tsis muaj ntshav siab.
Kev siv cov ntsiav tshuaj kuj tseem cuam tshuam rau kev paub ntau ntxiv ntawm thyroglobulin (TG), thaum kev noj zaub mov noj tsis nqa cov txiaj ntsig uas xav tau.
Atorvastatin txo cov roj cholesterol hauv cov neeg mob homozygous tsev neeg hypercholesterolemia, thaum tsis yog kev kho tshuaj thiab kev noj haus tsis ua rau lub cev lipid metabolism.
Atomax raug txwv rau qee pawg ntawm cov neeg mob. Cov kev qhia muaj ib daim ntawv teev cov khoom sib kis rau kev siv tshuaj:
- Cov menyuam yaus thiab hnub nyoog qis dua 18 xyoo.
- Lub sij hawm ntawm kev xeeb tub thiab pub niam mis.
- Kab mob siab Hepatic tsis paub meej keeb kwm.
- Kev tsis haum xeeb rau cov khoom siv hauv cov khoom.
Cov tshuaj yog sau ntawv nrog kev ceev faj thaum muaj kev cuam tshuam ntawm cov hlab ntsha hypotension, qhov tsis txaus ntawm electrolytes, malfunctions ntawm endocrine system, mob siab pathologies, mob ntev cawv thiab mob vwm, uas tsis tuaj yeem tswj tau.
Cov lus qhia rau kev siv tshuaj
Lub hauv paus tseem ceeb hauv kev kho Atomax yog kev soj ntsuam ntawm kev noj zaub mov tshwj xeeb. Khoom noj khoom haus txhawm rau txo qis kev noj cov zaub mov uas muaj cov cholesterol. Yog li, cov zaub mov tsis suav nrog kev noj viscera (ob lub raum, paj hlwb), qe qe, butter, nqaij npuas muaj roj, thiab lwm yam.
Kev noj tshuaj ntawm atorvastatin txawv ntawm 10 txog 80 mg. Raws li txoj cai, tus kws kho mob koom nrog tshuaj sau ntawv thawj zaug ntawm 10 mg rau ib hnub. Ntau yam ua rau muaj ntau npaum li cas ntawm ib hom tshuaj, xws li theem ntawm LDL thiab cov roj (cholesterol) tag nrho, cov hom phiaj ntawm kev kho thiab nws cov hauj lwm zoo.
Ua kom ntau dua qhov ntau npaum li cas tuaj yeem nqa tawm tom qab 14-21 hnub. Hauv qhov no, cov ntsiab lus ntawm lipids hauv cov ntshav ntshav yog qhov yuav tsum tau ua.
Tom qab 14 hnub ntawm kev kho mob, qhov kev txo qis hauv cov qib roj hauv qib siab tau pom, thiab tom qab 28 hnub cov kev kho mob siab tshaj plaws tau tiav. Nrog lub sijhawm ntev los kho, lipid metabolism rov zoo li qub.
Cov ntim ntawm cov tshuaj yuav tsum muab cia rau hauv qhov chaw tiv thaiv los ntawm ncaj qha tshav ntuj kom deb ntawm cov menyuam yaus. Qhov ntsuas kub ntawm qhov tso cia nws txawv ntawm 5 txog 20 degrees Celsius.
Txee lub neej yog 2 xyoos, tom qab lub sijhawm no cov tshuaj txwv tsis pub noj.
Tej yam yuav phom sij thiab raug ntau
Kev tswj hwm tus kheej ntawm cov tshuaj rau txoj kev kho cov tshuaj yog nruj me ntsis txwv tsis pub.
Qee zaum, ib qho tshuaj yuav ua rau muaj kev phiv tshuaj ntawm tus neeg mob.
Ua ntej siv Atomax, koj yuav tsum sab laj nrog koj tus kws kho mob.
Cov ntaub ntawv qhia hais tias qhov tshwm sim muaj feem ntawm cov kev mob tshwm sim:
- Kev tsis ncaj ncees ntawm lub hauv nruab nrab cov hlab ntsha: asthenic syndrome, pw tsis tsaug zog lossis tsaug zog, npau suav phem, qaug zog, dias taub hau, mob taub hau, ntxhov siab, tinnitus, teeb meem kev pabcuam, paresthesia, peripheral neuropathy, saj tsis zoo, qhov ncauj qhuav.
- Cov tshuaj tiv thaiv cuam tshuam nrog cov kabmob ntsig txog qhov tsis hnov tsw: kev txhim kho ntawm lag ntseg, lub qhov muag qhuav.
- Cov teeb meem ntawm cov hlab plawv thiab cov hlab ntsha ua haujlwm: phlebitis, anemia, angina pectoris, vasodilation, orthostatic hypotension, thrombocytopenia, nce plawv dhia, arrhythmia.
- Kev txiav txim siab ntawm lub plab zom mov thiab lub plab zom mov: kev cem quav, zawv plab, xeev siab thiab ntuav, mob plab, mob plab hnyuv tws, ua rau lub plab, ua rau lub siab kub, ua kom muaj roj ntau dua, muaj tus kab mob pancreatitis.
- Kev tawm tsam ntawm daim tawv nqaij: khaus, tawm pob, eczema, o ntawm lub ntsej muag, kev ua kom lub ntsej muag.
- Cov teeb meem ntawm cov leeg mus rau lub cev: mob plab hauv cov leeg ntawm cov leeg qis, mob hauv kev sib cog lus ntawm cov pob qij txha thiab sab nraub qaum, mob myositis, rhabdomyolysis, mob caj dab, exacerbation ntawm gout.
- Malfunctioning tso zis: tso zis qeeb, cystitis.
- Deterioration ntawm kev kuaj pom: hematuria (ntshav hauv cov zis), albuminuria (protein hauv cov zis).
- Lwm yam kev cuam tshuam: hyperthermia, txo qis kev sib deev muaj zog, ua haujlwm erectile, alopecia, tawm hws ntau dhau, seborrhea, stomatitis, cov pos hniav los ntshav, qhov quav, lub paum thiab lub qhov ntswg.
Kev noj tshuaj ntau dua ntawm atorvastatin ua rau muaj kev pheej hmoo mob raum, nrog rau myopathy (kab mob neuromuscular) thiab rhabdomyolysis (mob hnyav ntawm myopathy).
Txog hnub, tsis muaj ib yam tshuaj tshwj xeeb rau cov tshuaj no.
Yog tias cov cim qhia txog kev noj ntau dhau tshwm sim, lawv yuav tsum tau muab tshem tawm. Hauv qhov no, hemodialysis yog qhov ua tsis tau zoo.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj yeeb dej caw muaj zog tuaj yeem hloov pauv ntawm lawv tus kheej hauv kev sib txawv, vim tias qhov kev kho ntawm Atomax tuaj yeem nce lossis txo qis.
Qhov ua tau ntawm kev cuam tshuam ntawm cov tshuaj ntawm cov tshuaj ntau yam yuav tsum tau hais tias tus neeg mob yuav tsum qhia tus kws kho mob uas koom nrog kev noj tshuaj uas cuam tshuam rau Atomax cov haujlwm.
Hauv cov lus qhia rau kev siv tshuaj hypolipidemic, muaj cov ntaub ntawv tiav txog kev cuam tshuam nrog lwm cov tshuaj.
Cov kev qhia ceeb toom:
- Ua ke nrog kev kho mob nrog cyclosporine, erythromycin, fibrates thiab antifungal agents (pawg azoles) muaj kev pheej hmoo ntawm cov neuromuscular pathology - myopathy.
- Hauv kev tshawb nrhiav, kev tswj hwm tib lub sijhawm ntawm Antipyrine tsis ua rau muaj kev hloov pauv tseem ceeb hauv pharmacokinetics. Yog li ntawd, kev sib txuas ntawm ob qho tshuaj tau tso cai.
- Kev siv txig txuas ntawm kev ncua kev txiav txim siab uas muaj magnesium hydroxide lossis aluminium hydroxide, ua rau txo qis hauv cov ntsiab lus ntawm atorvastatin hauv ntshav.
- Kev sib xyaw ntawm Atomax nrog cov tshuaj txwv tswj uas muaj tinylestradiol thiab norethindrone tsub kom ntau dua AUC ntawm cov feem.
- Kev siv tib lub sij hawm ntawm colestipol txo cov theem ntawm atorvastatin. Qhov no nyeg txhim kho cov lipid-txo cov nyhuv.
- Atomax tuaj yeem nce cov ntsiab lus ntawm digoxin hauv cov hlab ntshav. Yog tias tsim nyog, kev kho mob nrog cov tshuaj no yuav tsum ua raws li kev saib xyuas mob nkeeg.
- Cov thawj coj ua ke ntawm Azithromycin tsis cuam tshuam rau cov ntsiab lus ntawm cov kev nquag ntawm Atomax hauv cov ntshav ntshav.
- Kev siv erythromycin thiab clarithromycin ua rau nce qib hauv atorvastatin hauv cov ntshav.
- Thaum cov chaw sim tshuaj, tsis pom muaj tshuaj lom ntawm Atomax thiab Cimetidine, Warfarin.
- Kev nce qib ntawm cov tshuaj nquag tau pom thaum cov tshuaj ua ke nrog cov tshuaj tiv thaiv protease.
- Yog tias tsim nyog, tus kws kho mob tso cai rau koj los sib xyaw Atomax nrog cov tshuaj, uas suav nrog Amplodipine.
- Cov kev tshawb fawb txog yuav ua li cas cov tshuaj cuam tshuam nrog cov tshuaj antihypertensive tsis tau ua.
Nrog kev sib xyaw ntawm Atomax nrog estrogens, tsis muaj qhov tshwm sim tsis zoo tshwm sim.
Nqe, tshuaj xyuas thiab analogues
Muaj cov xov xwm me me ntawm qhov ua tau zoo ntawm kev siv Atomax hauv Is Taws Nem. Qhov tseeb yog tias tam sim no, IV tiam statins raug siv rau hauv kev kho mob. Cov tshuaj no muaj qhov nruab nrab noj thiab tsis ua rau muaj kev mob tshwm sim ntau.
Atomax yog qhov nyuaj heev rau yuav hauv khw muag tshuaj ntawm lub teb chaws vim qhov tseeb tias tam sim no nws yuav luag tsis siv. Qhov nruab nrab, tus nqi ntawm ib pob (30 ntsiav tshuaj ntawm 10 mg) thaj tsam ntawm 385 txog 420 rubles. Yog tias tsim nyog, cov tshuaj yuav tuaj yeem txiav txim online nyob rau lub vev xaib ntawm cov tuam ntxhab.
Muaj ob peb tshuaj xyuas ntawm lipid-txo tus neeg sawv cev ntawm cov ncauj lus thematic. Rau feem ntau, lawv tab tom tham txog qhov tshwm sim ntawm kev phiv tshuaj thaum noj cov tshuaj. Txawm li cas los xij, nyias muaj nyias kev xav.
Vim muaj ntau yam contraindications thiab kev tsis zoo, qee zaum tus kws kho mob sau ib qho lus siv (cov tshuaj muaj tib yam tshuaj lom) lossis cov tshuaj tiv thaiv mob (muaj cov sib txawv ntawm cov tshuaj sib txawv, tab sis tsim cov tshuaj zoo sib xws).
Cov lus cim ntxiv ntawm Atomax tuaj yeem muas tau ntawm Lavxias kev ua lag luam tshuaj:
- Atovastatin (No. 30 ntawm 10 mg - 125 rubles);
- Atorvastatin-Teva (No. 30 rau 10 mg - 105 rubles);
- Atoris (No. 30 rau 10 mg - 330 rubles);
- Liprimar (No. 10 ntawm 10 mg - 198 rubles);
- Novostat (No. 30 rau 10 mg - 310 rubles);
- Tulip (No. 30 rau 10 mg - 235 rubles);
- Torvacard (No. 30 ntawm 10 mg - 270 rubles).
Ntawm cov tshuaj tiv thaiv zoo ntawm Atomax, nws yog qhov tsim nyog kom paub qhov txawv xws li cov tshuaj:
- Akorta (No. 30 rau 10 mg - 510 rubles);
- Krestor (naj npawb 7 rau 10 mg - 670 rubles);
- Mertenil (Zauv 30 rau 10 mg - 540 rubles);
- Rosuvastatin (Zaj 28 ntawm 10 mg - 405 rubles);
- Simvastatin (No. 30 ntawm 10 mg - 155 rubles).
Tau ua tib zoo kawm cov tshuaj Atomax, cov lus qhia rau kev siv, nqi, analogues thiab cov tswv yim ntawm cov neeg siv khoom, tus neeg mob, ua ke nrog tus kws tshaj lij uas tuaj koom, yuav muaj peev xwm soberly ntsuas qhov xav tau rau kev noj tshuaj.
Cov ntaub ntawv hais txog statins yog muab hauv video hauv tsab xov xwm no.
