Kev cai tswj cov roj (cholesterol) thiab cov roj (cholesterol) ua ke

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Cov roj (cholesterol) yog ib yam tseem ceeb uas koom nrog lipid metabolism thiab synthesizes ntau dua ib qho hormone. Nws muaj nyob hauv yuav luag txhua lub hlwb. Cov lus qhia dav dav rau lub npe yog cov roj (cholesterol).

Thawj lub npe tau muab rau nws thaum xyoo 1859, thaum cov kws tshawb fawb pom tias cov khoom yog cawv. Los ntawm lub cev, nws tau muab tso ua ke kom muaj ntau dua ntawm nws tus kheej, thiab ib qho me me los ntawm zaub mov. Nws yog ib qho tseem ceeb tias kev noj zaub mov zoo kom nws ua tau yooj yim.

Feem ntau muaj kev ua txhaum ntawm cov txheej txheem ntawm cov cholesterol. Qhov no tshwm sim rau ntau yam, tab sis ntau zaus nws tshwm sim vim qhov tsis tseeb hauv kev noj haus. Qhov xwm txheej no ua rau tsis zoo rau kev noj qab haus huv thiab ua rau muaj mob hnyav.

Feem ntau, lipoproteins cov nqi ib txwm tuaj yeem ua cov haujlwm hauv qab no:

  • ua lub hauv paus ntawm cov xaum;
  • koom rau hauv kev sib txuas ntawm cov tshuaj hormones;
  • pab cov synthesis ntawm cov vitamin D;
  • koom nrog hauv cov metabolism;
  • koom nrog kev tsim kom muaj bile;
  • yog ib feem ntawm cov tshuaj ntawm cov hlab ntsha hlwb;
  • koom rau hauv cov hluavtaws cov serotonin;
  • ntxiv dag zog rau kev tiv thaiv;
  • muab lub cev zoo li qub ntawm lub hauv nruab nrab lub paj hlwb.

Qhov loj tshaj plaws yog tias qhov hluavtaws ntawm cov roj (cholesterol) yog qhov ib txwm ua. Kev ua txhaum cov txheej txheem no cog lus tias ua tsis tiav ntawm txhua lub cev. Txhawm rau paub txog kev tiv thaiv koj tus kheej los ntawm cov xwm txheej dab tsi, koj yuav tsum paub txog yuav ua li cas cov kev cai ntawm cov roj (synthesis) thiab nws cov txheej txheem tshwm sim.

Kev sib txuas ntawm cov roj (exogenous) (sab hauv) cov roj yuav tuaj yeem pom nyob rau hauv tag nrho cov ntaub so ntswg.

Feem ntau ntawm cov txheej txheem tshwm sim hauv lub siab.

Nws cov keeb puag thaum ub hu ua Acetyl-Coa.

Cov roj ntsha muab tshuaj tua kab mob roj (biosynthesis) yuav tshwm sim raws li cov qauv no:

  1. Mavalonic acid yog tsim los.
  2. Cov kua qaub tau hloov pauv mus rau isoprene nquag, los ntawm cov uas squalene tseem hluavtaws.
  3. Squalene hloov dua siab tshiab rau sterol.

Txog ib gram ntawm cov tshuaj steroid tuaj yeem tsim nyob hauv ib hnub. Tus qauv tshuaj lom neeg ntawm cov khoom yog C27H45OH. Qhov tshuaj tiv thaiv no tshwm sim nrog kev koom nrog ntawm 30 enzymes uas ua raws li catalysts hauv cell cytoplasm. Ib qhov nqi ntawm cov khoom hloov mus rau hauv ethers, sib txuas nrog cov roj ntsha sib xyaw nrog txhua lwm yam, ces cov roj cholesterol catabolism tshwm sim. Cov sib txuam tau tsim nyob hauv cov qog adrenal, cov qog, thiab gonads. Tom qab, cov tsim tsim yuav dhau los ua kev txuam nrog cov tshuaj hormones, qhov tsim ntawm cov kua tsib.

Muaj lwm hom roj (cholesterol) - exogenous. Nws nkag mus rau hauv lub cev nrog cov khoom noj, feem ntau nrog cov zaub mov uas muaj cov rog tsiaj. Kev puas tsuaj ntawm cov roj cholesterol esters yuav tshwm sim siv cov enzyme - "cov cholesterol." Cov rog ua los ntawm qhov no nkag mus rau cov qe ntshav ntawm txoj hnyuv thiab tau nqus rau hauv cov hlab ntshav, tom qab ntawd lawv nkag mus rau hauv lub siab.

Cov tshuaj yog thauj los ntawm cov ntaub so ntswg nrog kev pab los ntawm cov protein tshwj xeeb - lipoproteins. Lawv muaj peb hom:

  • Cov lipoproteins tsawg kawg (LDL) tsis zoo. Cov tshuaj yog thauj mus rau hauv cov ntaub so ntswg, thiab nws dhau mus yog tau tuaj yeem khom ntawm phab ntsa ntawm cov hlab ntshav, ua cov plahaum plahaum. Txoj kev no provokes qhov tshwm sim ntawm atherosclerosis.
  • Cov lipoproteins tsawg heev (VLDL). Lawv koom nrog hauv kev thauj khoom ntawm triglycerides thiab lwm yam sib txuas. Hom no yog qhov txaus ntshai tshaj plaws, vim tias nws tuaj yeem ua tus sclerosis.
  • Kev kub ceev Lipoproteins (HDL). Nws yog cov khoom sib txuam uas tuaj yeem nqus cov roj ntau dhau thiab hloov mus rau ntawm daim siab. Lawv koom nrog kev tshem tawm cov teeb meem roj cholesterol thiab inhibit kev txhim kho atherosclerosis.

Rau kev noj qab haus huv ntawm lub cev, sib npaug ntawm cov tebchaw no yog qhov tseem ceeb. Thaum kuaj xyuas, them nyiaj rau tag nrho cov qib roj (cholesterol). Kev sib txawv ntawm tus qauv qhia tau tias muaj teeb meem mob. Qhov ntsuas ntawm tag nrho cov cholesterol yog cuam tshuam los ntawm:

  1. cov theem ntawm kev ua ub no ntawm kev tsim cov khoom hauv lub siab;
  2. qib ntawm kev nqus ntawm cov khoom los ntawm txoj hnyuv me;
  3. metabolism hauv lipoproteins;
  4. kev ua si ntawm cov kev tshem tawm cov roj cholesterol los ntawm cov kua tsib kua qaub.

Txhua tus neeg muaj lawv tus kheej cov roj (cholesterol) zoo. Nws nyob ntawm poj niam txiv neej, hnub nyoog. Nws yuav tsum raug sau tseg tias hauv cov txiv neej, nrog lub hnub nyoog, cov khoom yuav nce ntxiv, thaum nyob hauv poj niam, ntawm qhov tsis sib xws, nws tuaj yeem txo qis.

Cov roj cholesterol ua rau muaj kev rau txim.

Txawm hais tias xws li pathology tshwm sim ntau tsawg dua li ib qho kev nce, tab sis nws tsis muaj kev phom sij.

Nws raug nquahu kom soj ntsuam kev noj haus thiab kev ua neej.

Cov roj (cholesterol) qis tau hauv:

  • Kab mob sib kis ntau yam.
  • Lub plawv tsis ua hauj lwm.
  • Mob ntsws qhuav.
  • Mob siab mob cancer.
  • Mob stroke.
  • Mob hlwb.
  • Sepsis.
  • Mob Kev Plab
  • Hyperthyroidism.

Hauv cov txiv neej, cov kab mob pathology provokes kev sib deev tsis txaus ntseeg, hauv cov poj niam, nyob rau hauv nws cov cawv, kev tsis sib haum xeeb tshwm sim.

Yog hais tias tus kab mob loj hlob tuaj thaum lub sijhawm xeeb tus menyuam, muaj qhov txaus ntshai ntawm kev txhim kho tus menyuam hauv plab. Cov menyuam mos yug tshiab feem ntau muaj rickets.

Yog tias tag nrho cov khoom hauv lub cev nce, qhov ntxim nyiam ntawm kev tsim cov kabmob muaj yog tseem siab.

Lub sijhawm ntev ntawm cov roj (cholesterol) siab tuaj yeem ua rau:

  1. angina pectoris;
  2. kev mob plawv hauv lub plawv;
  3. mob plawv nrog ntshav qab zib;
  4. tus cwj nrag;
  5. endometitis;
  6. ntshav siab

Qhov phom sij yog qhov kev ua txhaum cai tau tsis muaj cov tsos mob hais tawm. Yog li, nws yog qhov tseem ceeb uas yuav tsum tau mus kuaj mob raws sij hawm, lossis ntsuas nws cov kev ua tau zoo hauv tsev.

Yog tias tsis muaj kev kho mob sijhawm, kab mob ntawm hom no tuaj yeem ua rau muaj kev tsis taus thiab kev tuag.

Kev nce rog hauv lub siab tshwm sim thaum lub cev metabolism tsis zoo, yog li cov txheej txheem no yuav tsum tau tshwj xeeb.

Lub npe scientific rau lub pathology yog hyperlipidemia.

Tus mob no qhia hais tias lub cev muaj qhov loj ntawm LDL.

Yeej, nws nce siab vim:

  • Passive lub neej.
  • Tshaj qhov hnyav.
  • Khoom noj khoom haus tsis muaj zog.
  • Caj ces quav.
  • Mob ntshav qab zib Hom 2.
  • Txuas cov ntaub so ntswg mob.
  • Haus dej cawv.
  • Haus Yeeb.
  • Kev ntxhov siab tas mus li.
  • Noj qee yam tshuaj.
  • Laus lub caij nyoog.

Tus nqi qes tshwm sim rau lwm yam. Nws kuj tseem muaj cov ntsiab lus uas txo nws txoj catabolism: cuam tshuam ntawm lub qog ua haujlwm lub qog thiab muaj cov kab mob siab. Nws yog qhov tshwj xeeb tshaj yog qhia tshwj xeeb tshaj yog kev cais tawm ntawm cov rog hauv cov zaub mov, thaum noj qee yam tshuaj. Tseem muaj tus lej ntawm lwm cov laj thawj, nrog rau kev noj zaub mov nruj; lub caij nyoog ua haujlwm nrawm; muaj qhov mob huam; mob ntsws qhuav; kab mob plawv.

Txhawm rau kom tsis txhob pathologies, nws yog ib qho tsim nyog yuav tsum tau soj ntsuam rau lipoproteins, ntshav biochemistry tseem tabtom tshawb xyuas. Kev tshawb nrhiav biochemical yuav qhia tawm txawm tias qhov kev cuam tshuam tsis zoo hauv cov ntshav, txiav txim siab lub xeev ntawm cov keeb kwm qog: thyroid, cov tshuaj tiv thaiv kev sib deev. Nws raug nquahu los tshawb xyuas lub xeev ntawm lub cev kom zoo. Cov ntsiab lus rau txoj kev tshawb fawb yuav yog:

  1. Feem ntau yog cov rog dhau, lossis muaj qhov hnyav dhau.
  2. Kev tiv thaiv ntawm atherosclerosis, lossis keeb kwm ntawm nws.
  3. Mob Vascular.
  4. Kab mob ntawm daim siab, lub raum.
  5. Mob ntshav qab zib mellitus.

Nws raug nquahu kom tsis txhob noj 12 teev ua ntej txheej txheem. Kev tsom xam yog nqa tawm ntawm lub plab khoob. Txhawm rau kom lipoproteins ua tau zoo, yuav tsum raug cais tawm.

Koj yuav tsum tshem cov zaub mov uas muaj LDL los ntawm kev noj haus, ua kom cov txiv hmab txiv ntoo thiab zaub ntau dua, tswj kev siv cov khoom sib xyaw thiab cov khoom qab zib, hloov butter nrog zaub.

Kev tswj hwm cov roj khov tuaj yeem nqa tawm ntawm nws tus kheej, qhov tseem ceeb tshaj plaws yog tshem tawm cov kev coj ua tsis zoo los ntawm lub neej thiab pib txav mus ntau, ces kev noj qab haus huv yuav ib txwm nyob ib txwm.

Txoj kev sib txuas ua ke thiab thauj cov cholesterol hauv lub cev tau piav qhia hauv video hauv kab lus no li cas.

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