Klava hais txog cov neeg ua hauj lwm antimicrobial muaj zog ntawm pawg loj ntawm penicillins. Nws muaj qhov kev ua kom ncaj ncees qhov dav. Nws yog ob qho tib si rau kev kho mob ntawm cov txheej txheem mob hauv nruab nrog, thiab rau kev kho mob osteoarticular.
ATX
ATX Code: J01CR02.
Klava hais txog cov tshuaj tua kab mob muaj zog. Nws yog npaj rau kev kho mob hauv cov txheej txheem hauv lub cev.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj no muaj nyob hauv 2 daim ntawv qhia loj: cov ntsiav tshuaj thiab hmoov rau kev ncua. Cov tshuaj phiv yog amoxicillin thiab clavulanic acid.
Ntsiav tshuaj
Cov ntsiav tshuaj yog convex, dawb. Muaj qhov npog tshwj xeeb tiv thaiv. Txhua lub ntsiav tshuaj muaj 250 il 500 mg ntawm amoxicillin thiab 125 mg ntawm acid. Cov tshuaj ntxiv: hmoov txhuv nplej siab, silicon dioxide, magnesium stearate, cellulose thiab talc.
Hmoov
Lub hmoov no homogeneous, crystalline, dawb. 5 ml ntawm qhov kev ua tiav tiav muaj 125 mg ntawm amoxicillin thiab 31 mg ntawm clavulanate. Ntu cov khoom siv: citric acid, sodium benzoate, pos hniav thiab mint tsw.
Cov tshuaj phiv tshuaj ntawm cov tshuaj yog amoxicillin thiab clavulanic acid.
Mechanism ntawm kev ua
Nws yog cov tshuaj tua kab mob ntau yam. Nws yog siv los kho ntau yam kab mob, tshwj xeeb tshaj yog nyob rau hauv chaw puag.
Amoxicillin yog ib qho txiaj ntsig ntawm penicillins. Clavulanic acid yog ib qho muaj zog beta-lactamase inhibitor.
Cov tshuaj muaj cov nyhuv ntawm gram-zoo thiab gram-tsis zoo, aerobic thiab qee qhov anaerobic pathogenic microorganisms uas nkag siab rau penicillins.
Cov nyhuv pharmacological yog ua raws li qhov tseeb tias cov kua qaub ua ke sib xyaw sai nrog beta-lactamases thiab tsim cov qauv tshwj xeeb ruaj khov. Yog li ntawd, cov tshuaj tua kab mob tiv thaiv rau qhov tsis zoo ntawm cov enzymes zais cia los ntawm cov kab mob pathogenic nce. Qhov no ua rau muaj qhov tseeb tias qhov mob rhiab ntawm cov kab mob rau kev cuam tshuam ntawm amoxicillin ntawm lawv nce.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yog nqus zoo los ntawm lub plab zom mov. Kev tshem tawm kom zoo dua yog tias noj tshuaj ua ntej noj mov.
Qhov siab tshaj plaws ntawm amoxicillin hauv ntshav yog pom nyob hauv ib teev tom qab kev coj noj coj ua. Tag nrho cov khoom siv tau faib zoo nyob rau ntau lub plab hnyuv siab raum thiab lub kaw lus. Lawv tuaj yeem pom nyob hauv lub ntsws, yug menyuam thiab lub plab hauv plab. Ib nrab-lub neej yog li 2 teev. Cov tshuaj yog tawm hauv lub cev los ntawm kev ua kom muaj cov metabolites loj los ntawm kev rov ua paug.
Kev ntsuas rau siv
Cov cim tseem ceeb rau kev siv yog:
- mob ntsws sai sai ntawm cov kab mob keeb kwm;
- otitis media;
- exacerbated mob ntsws ntev;
- mob ntsws
- cov kab mob cystitis;
- pyelonephritis thiab lwm yam kev mob tshwm sim hauv lub raum;
- kis kab mob ntawm daim tawv nqaij thiab cov nqaij mos;
- tsiaj tom;
- kis cov kab mob sib kis;
- osteomyelitis thiab lwm qhov mob ntawm cov leeg ua leeg.
Cov Yuav Tsum Muaj
Kev siv tshuaj hauv cov xwm txheej zoo li no tsis tso cai:
- kev tsis qaug rau cov tshuaj ntawm cov tshuaj;
- kev siv tshuaj tiv thaiv kev tsis haum rau cov tshuaj beta-lactamase;
- cov menyuam tsis tau muaj 12 xyoos;
- cev xeeb tub thiab lactation.
Nrog kev saib xyuas zoo, ntsiav tshuaj yuav tsum tau noj rau cov neeg tsis hnov mob lub raum thiab mob siab (ob qho tib si mob thiab mob hauv nruab nrog).
Nrog kev saib xyuas zoo, ntsiav tshuaj yuav tsum tau noj rau cov neeg muaj lub siab tsis ua hauj lwm zoo.
Yuav noj li cas?
Qhov ntau npaum li cas thiab kev kho mob ntev li cas tau txiav txim rau txhua tus neeg mob nyob ntawm lub hnub nyoog thiab poj niam txiv neej, mob hnyav ntawm cov kab mob hauv qab thiab muaj cov kab mob raum. Tab sis cov chav kawm ntawm kev kho mob yuav tsum tsis pub tshaj 14 hnub.
Cov neeg loj thiab menyuam yaus hnub nyoog 12 xyoos tshaj sau ntawv yuav tsum tau 1 ntsiav tshuaj ntawm 325 mg txhua 8 teev lossis 1 ntsiav tshuaj ntawm 625 mg txhua 12 teev. Hauv kev ua txhaum loj dua, 625 mg ntawm qhov tshuaj tau hais kom ua txhua 8 teev.
Qhov siab tshaj uas tau tso cai noj ib hnub ntawm amoxicillin yuav tsum tsis pub tshaj 600 mg.
Cov menyuam yaus lub cev hnyav dua 40 kg tau sau tseg 375 mg ntawm cov tshuaj txhua 8 teev. Yog tias muaj kev mob tshwm sim heev, koj tuaj yeem nce lub sijhawm ntxiv ntawm kev noj tshuaj pab txog 12 teev.
Thaum mus khomob, haus dej kom ntau yog qhov zoo. Rau kev nqus zoo dua, nws raug nquahu kom haus cov ntsiav tshuaj ua ntej noj mov loj.
Sab sij huam
Thaum noj tshuaj tiv thaiv kab mob, ntau yam kev phiv tshuaj tshwm sim feem ntau tshwm sim. Txhua tus ntawm lawv yuav tsum dhau los ntawm nws tus kheej, tsis tas yuav muaj kev cuam tshuam kev kho mob tam sim ntawd tom qab tshem yeeb tshuaj.
Los ntawm cov hnyuv
Cov neeg mob muaj mob xeev siab thiab ntuav, raws plab. Muaj qee zaus, pseudomembranous colitis tshwm sim. Hauv cov menyuam yaus, qee zaum koj tuaj yeem pom qhov hloov pauv ntawm cov xim ntawm txha hniav laus.
Kev ua xua tsis haum
Qee zaum cov neeg mob yws ntawm cov tsos mob tshwj xeeb ua pob rau ntawm daim tawv nqaij, khaus thiab kub hauv thaj chaw cuam tshuam. Feem ntau, ua xua, dermatitis, pustulosis, candidiasis ntawm daim tawv nqaij thiab mucous daim nyias nyias nthuav dav. Thaum muaj mob hnyav, Stevens-Johnson syndrome, Lyell tshwm sim, Quincke's edema lossis txawm tias anaphylactic shock tuaj yeem pom nws tus kheej. Txoj kev pheej hmoo ntawm kev tsim exanthema yog nce.
Los ntawm lub hauv nruab nrab poob siab
Kev tsaus muag heev thiab mob taub hau, tsis yog lub txiaj ntsig. Cov tsos mob ntawm tus mob huam tsis tuaj yeem yog qhov ua tau, tab sis nws tau pom tsuas yog thaum muaj kev noj haus ntau dhau los yog nyob ntawm qhov muaj keeb kwm ntawm cov mob nephropathy hauv tus neeg mob.
Los ntawm ob lub raum thiab mob txeeb zig
Feem ntau muaj crystalluria. Hauv ntau tus neeg mob, cov txheej txheem ua mob hauv ob lub raum tau ntxiv rau qhov pom, tab sis tsuas yog ntawm qhov tsis yog-kis tau.
Los ntawm cov kab mob hematopoietic
Hauv kev kuaj ntshav, muaj qhov txo qis ntawm neutrophils thiab leukocytes, thrombocytopenia, hemolytic anemia. Feem ntau, kev noj tshuaj cuam tshuam rau tus nqi ntawm cov ntshav coagulation.
Los ntawm lub siab
Qhov pom ntawm cholestatic jaundice tau sau tseg. Qee zaum cov txheej txheem o tshwm sim hauv lub siab. Kab mob siab feem ntau pib tiv thaiv keeb kwm ntawm ib tus kab mob ntev ntev ntawm cov kab mob siab.
Yog tias daim siab ua haujlwm tsis zoo vim los ntawm kev kho mob, thiab cov tsos mob daj ntseg sai sai, nws zoo dua los hloov cov kab mob antibacterial.
Cov lus qhia tshwj xeeb
Nrog kev ceev faj, cov tshuaj tau raug muab rau cov neeg mob nquag ua xua. Ceev faj yuav tsum tau siv thaum muaj qhov ua siab luv rau cephalosporins.
Rau cov neeg mob uas muaj lub siab thiab lub raum tsis ua haujlwm, yuav tsum saib xyuas tas li ntawm cov kab mob no, thiab yuav tsum kho kom tsawg yog tias muaj qhov tsis zoo rau tag nrho kev noj qab haus huv thiab kuaj tau.
Thaum lub sij hawm ntawm kev kho, nws yog qhov zoo dua kom tso tseg kev tsav tus kheej.
Kev noj cov tshuaj no hauv qee kis tuaj yeem ua rau tsis meej pem, cuam tshuam rau qhov ceev ntawm psychomotor kev xav thiab kev saib xyuas, uas yog tsim nyog thaum muaj xwm txheej ceev. Yog li ntawd, thaum lub sijhawm kho, nws zoo dua rau kev tso tseg kev tsav tus kheej.
Siv thaum cev xeeb tub thiab lactation
Tsis txhob noj tshuaj thaum cev tes. Cov tshuaj lom neeg mob tau nkag mus zoo los ntawm kev tiv thaiv lub cev ntawm tus txiv neej thiab tej zaum yuav muaj qhov tsis xav ua rau lub cev xeeb tub. Yog tias tsim nyog, Klavama kev tswj hwm tau raug sau tseg tsuas yog nyob rau theem tom ntej, thaum kev tsim ntawm tus me nyuam ua tiav. Tab sis hauv qhov no, kev noj tshuaj yuav cuam tshuam tsis zoo rau kev noj qab haus huv ntawm tus menyuam.
Cov tshuaj yeeb dej caw kuj tseem muaj nyob hauv niam mis. Yog li, rau lub sijhawm kho, nws zoo dua rau kev pub mis niam.
Klavama lub sijhawm teem rau cov menyuam yaus
Cov tshuaj hauv daim foos tshuaj tsis raug txwv rau cov menyuam yaus hnub nyoog qis dua 12 xyoos.
Noj ntau dhau
Yog tias koj huam yuaj ntau dua qhov tshuaj, cov tsos mob ntawm intoxication tshwm sim. Feem ntau cov no yog mob dyspeptic. Ib qho kev sib xyaw ntawm cov kev phiv tshuaj tiv thaiv loj yuav pom.
Nyob rau hauv cov ntaub ntawv ntawm loj heev noj, pais plab lavage ua thiab detoxification txoj kev kho yog nqa tawm. Tom qab ntawd kho sorbents. Qhov kev kho mob tseem ceeb yog tsos mob. Txhawm rau tshem tawm tag nrho cov co toxins los ntawm lub cev, hemodialysis tau ua.
Kev cuam tshuam nrog lwm yam tshuaj
Probenecid muaj feem cuam tshuam tus nqi ntawm kev tso tawm ntawm amoxicillin los ntawm lub cev, thaum nws tsis cuam tshuam rau clavulanic acid. Kev siv sib koom ua ke ua rau muaj kev nce siab ntxiv hauv cov concentration ntawm cov tshuaj txuam hauv cov ntshav.
Amoxicillin inhibits qhov tsis pom kev ntawm methotrexate, uas ua rau nws muaj tshuaj lom rau hauv lub cev. Allopurinol provokes kev txhim kho kev ua xua.
Qhov kev ua tau zoo ntawm kev tiv thaiv qhov ncauj thaum sib xyaw nrog Clavam yog txo qis.
Yog tias siv ib txhij nrog aminoglycosides, ces kev ua txhaum ntawm kev nqus ntawm cov tshuaj thiab qeeb hauv nws qhov kev tshem tawm yog ua tau. Paracetamol yuav ua rau hnyav zog cov kev mob tshwm sim.
Tsis txhob siv cov khoom no nrog cawv, li kev kho mob nyhuv yuav txo kom tsawg, thiab cov tsos mob ntawm intoxication yuav nce.
Analogs
Muaj ntau ntau cov analogues uas yuav sib txawv me ntsis hauv qhov muaj pes tsawg leeg, tab sis cov kev kho kom zoo yuav luag zoo li qub. Cov feem ntau cov analogues:
- Amoxiclav;
- Amoxil-K;
- Augmentin;
- Ntse;
- Medoclave;
- Flemoklav Solutab;
- Amoxicomb.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj muaj peev xwm yuav tau ntawm lub tsev muag tshuaj raws li cov ntawv sau tshuaj tshwj xeeb muab los ntawm tus kws kho mob koom nrog.
Nqe rau Klava
Tus nqi yog nyob ntawm daim ntawv tso tawm, cov naj npawb ntawm cov ntsiav tshuaj hauv pob thiab cov khw muag tshuaj muaj npoo. Tus nqi nruab nrab ntawm cov tshuaj yog li ntawm 120 txog 600 rubles.
Cia rau cov neeg mob Klavam
Cov tshuaj yuav tsum muab tso kom deb ntawm cov menyuam yaus thiab nyiam dua hauv qhov chaw tsaus. Kev cia khoom kub yuav tsum tsis pub tshaj chav sov.
Hnub tas sij hawm
2 xyoos txij li hnub ntawm kev tsim khoom lag luam, uas yuav tsum tau hais qhia ntawm thawj lub ntim.
Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Klava
Kev tshuaj xyuas txog cov tshuaj yog sab laug los ntawm ob tus kws kho mob thiab cov neeg mob.
Cov kws kho mob
Olkhovik O.M.
Feem ntau kuv sau Clavam ntsiav tshuaj rau kuv cov neeg mob kom kho cov kab mob. Cov tshuaj ua haujlwm zoo heev, tab sis muaj ntau yam tshwm sim, yog li tsis yog txhua tus tuaj yeem noj nws. Tab sis feem ntau, cov neeg mob txaus siab rau kev kho mob, vim hais tias kev pab nyem sai sai.
Bozhok S.L.
Nws yog kev kho mob zoo rau kev kis tus kab mob. Haum rau ntau tus neeg mob thiab ua sai sai. Tab sis qee tus tsis txaus siab muaj qhov tshwm sim tsis dhau lub sijhawm.
Cov neeg mob
Olga, 27 xyoo
Nyuam qhuav raug mob los ntawm cov mob otitis. Tus kws kho mob tau sau rau Klavama ntsiav tshuaj. Lawv pab tau tam sim ntawd, tom qab ob peb hnub ntawm kev noj nws kuv xav zoo. Kuv tsis xav tias muaj kev phiv tshwj xeeb, tsuas yog nyob rau thawj hnub ntawm kev kho mob muaj me ntsis kiv taub hau thiab xeev siab. Kuv txaus siab nrog kev kho mob.
Andrey, 40 xyoo
Kuv tsis tuaj yeem noj tshuaj. Raws li nws tau muab tawm tom qab, Kuv ua xua rau cephalosporins thiab penicillins. Tom qab thawj cov ntsiav tshuaj, tawm pob tshwm rau ntawm daim tawv nqaij, thiab Quincke's edema tau tsim. Tsis tas li ntawd, muaj mob zawv plab thiab ntuav heev. Kuv yuav tsum tau hloov kho.
Elizabeth, 34 xyoo
Kuv tau txaus siab rau kev kho mob nrog cov tshuaj no. Lub ncoo noj tau yooj yim rau kev noj. Lawv tau pleev xim thiab yog li ntawd nqos zoo. Cov nyhuv manifested nws tus kheej nyob rau hnub thib ob ntawm kev kho mob. General mob tau zoo dua. Tsuas yog thaum pib kho mob xwb nws tau mob hnyav thiab mob plab tau ob peb zaug. Tom qab ntawd tsuas yog mob taub hau me ntsis, tab sis tom qab kev kaw tsis raug kho, txhua yam ploj mus.
