Maninil 5 yog ib qho tshuaj hypoglycemic siv los kho ntshav qab zib.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Glibenclamide.
Maninil 5 yog ib qho tshuaj hypoglycemic siv los kho ntshav qab zib.
ATX
A10VB01 - Glibenclamide.
Tso cov ntawv thiab cov nyob ua ke
Tiaj, muaj cov kab ua muaj kabmob hauv lub khauj khaum. Cov xim ntawm lub plhaub yog paj yeeb. Lub hauv paus ua haujlwm tseem ceeb yog glibenclamide, uas tau qhia hauv kev npaj hauv cov ntawv micronized. Qhov muaj pes tsawg leeg tau ntxiv nrog talc, gelatin, lactose monohydrate, qos hmoov txhuv nplej siab, magnesium stearate, zas xim daj.
Pharmacological kev txiav txim
Glibenclamide txo qis qib kev ua kom puas siab ntsws ntawm beta hlwb los ntawm cov piam thaj, uas nkag mus rau hauv lub cev nrog zaub mov, yog li ua rau lub plab zom mov tsim cov tshuaj insulin kom txaus.
Cov tshuaj tsub ntxiv insulin rhiab heev, ua kom nrawm nrawm ntawm qhov kev tiv thaiv ntawm cov tshuaj hormones rau lub hlwb. Ua rau ua kom nrawm tso tawm ntawm cov tshuaj insulin. Nws inhibits qhov txheej txheem ntawm lipolysis nyob rau hauv cov ntaub so ntswg adipose.
Cov Tshuaj Pharmacokinetics
Kev kho kom zoo li ib hnub, cov tshuaj pib ua 1.5-2 teev tom qab thov. Lub Cheebtsam ua haujlwm nrawm thiab nrawm hauv lub cev. Qhov siab tshaj plaws hauv cov ntshav tau pom tom qab 2-2.5 teev. Qhov feem pua ntawm khi rau cov ntshav protein yog 98%.
Qhov tseem ceeb ntawm cov tshuaj undergoes txheej txheem metabolic hauv daim siab mob siab, vim qhov tshwm sim ntawm ob qhov kev tiv thaiv tsis zoo. Ib ntawm lawv yog excreted nrog zis, lwm qhov nrog bile.
Txoj kev tshem tawm ib nrab-lub neej yuav siv 7 teev, thiab rau cov neeg muaj tus kab mob ntshav nws yuav siv sijhawm ntev dua.
Kev ntsuas rau siv
Nws yog tshuaj nyob rau hauv kev kho mob ntawm hom 2 insulin-dependant ntshav qab zib mellitus. Kev noj tshuaj yog qhov tsim nyog thaum nws tsis tuaj yeem ua kom lub cev zoo ntxiv nrog kev noj zaub mov zoo thiab ua haujlwm lub cev. Hauv kev kho mob ntshav qab zib, cov tshuaj yog kws kho nyob rau hauv kev sib txuas ua ke nrog lwm tus neeg mob hypoglycemic, ntxiv rau glinides thiab sulfonylureas.
Cov tshuaj tau sau tseg rau hauv kev kho mob ntawm hom 2 insulin-dependant diabetes mellitus.
Cov Yuav Tsum Muaj
Txais tos ntawm tus neeg sawv cev hypoglycemic yog tsis tuaj yeem ua haujlwm nyob rau hauv xws li:
- Yam 1 ntshav qab zib mellitus;
- precoma, coma;
- decompensated metabolic ntshawv siab;
- lub sijhawm rov qab tom qab tshem tawm cov thyroid caj pas;
- decompensated carbohydrate metabolism los ntawm kis kab mob;
- pais plab paresis;
- leukopenia;
- ua txhaum ntawm cov txheej txheem ntawm kev nqus ntawm cov khoom noj;
- ntshav qog.
Nws yog txwv tsis pub noj nyob rau hauv lub xub ntiag ntawm ib tug neeg intolerance mus rau tus neeg lub Cheebtsam ntawm cov tshuaj.
Nrog saib xyuas
Tus txheeb ze contraindications yog:
- ua npaws;
- kev cuam tshuam ntawm cov thyroid caj pas;
- pituitary hypofunction;
- haus cawv ntau dhau thiab tsis tu ncua, txhua theem ntawm kev haus cawv ntau dhau.
Hauv cov xwm txheej no, cov tshuaj tau tawm los tsuas yog rau cov cim tshwj xeeb, thaum lwm tus neeg mob hypoglycemic tsis tuaj yeem muab cov tshuaj kho kom zoo. Nrog kev ceev faj, cov tshuaj no tau hais tawm rau cov neeg muaj hnub nyoog 65 xyoos. Hauv cov neeg mob laus, yog qhov muaj feem ntau ntawm cov qog ntshav qab zib.
Yuav ua li cas noj Maninil 5?
Lub chav kawm ntawm kev kho mob pib nrog qhov tsawg kawg los yog nruab nrab qhov ntau, uas yuav tsum tau nce ntau zuj zus. Thawj koob tshuaj yog 2.5 mg lossis 5 mg (ib nrab lossis ib ntsiav tshuaj tag nrho), noj 1 zaug nyob rau ib hnub. Tsuas noj nce ntxiv rau 1 lub lis piam kom txog thaum nws raug coj los kho cov lus pom zoo.
Yog tias tus kws kho mob tau sau 2 daim ntawv rau noj, lawv yuav tsum siv 1 zaug nyob rau ib hnub. Yog tias tsim nyog, noj los ntawm 3 lossis ntau dua ib ntsiav tshuaj hauv ib hnub, qhov tshuaj yuav tsum tau muab faib ua ob peb zaug raws li cov txheej txheem - feem ntau ntawm cov tshuaj thaum sawv ntxov, tsawg dua yav tsaus ntuj.
Nrog ntshav qab zib
Hauv chav kawm tsis txawv ntawm hom ntshav qab zib hom 2, koob tshuaj txhua hnub yog 2.5 mg. Txoj kev mob hnyav ntawm tus mob yog 15 mg / hnub. Ntsiav tshuaj yog qaug 1 zaug. Yog tias qhov ntau npaum ntawm 15 mg yog qhov tau hais tseg, nws tau faib ua 2-3 koob tshuaj ib hnub. Cov ntsiav tshuaj yuav qaug cawv tag nrho yam tsis ntxo.
Cov tshuaj yog noj 30 feeb ua ntej noj mov loj.
Cov tshuaj yog noj 30 feeb ua ntej noj mov loj. Yog tias qhov muaj zog zoo dua qub los ntawm kev siv cov tshuaj tiv thaiv hypoglycemic tsis tuaj rau 1-1.5 lub hlis, cov tshuaj yuav tsum tau hloov.
Kev phiv los ntawm Maninil 5
Feem ntau muaj cov tsos mob ntawm disulfiram zoo li cov tshuaj tiv thaiv - xeev siab, mob plab, raws plab, mob taub hau, kub cev. Tsis tshua muaj: tsis pom kev pom tseeb, lub siab ua haujlwm tsis zoo.
Kev kho mob txoj hnyuv
Xeev siab, ntuav feem ntau ntuav, zoo nkaus lub plab thiab qhov hnyav ntog hauv nws. Mob mob hauv plab, ntau zaus, zawv plab, saj ntawm cov hlau ntawm qhov ncauj kab noj hniav. Lub xub ntiag ntawm cov tsos mob no tsis tas yuav tsum tsis txuas lub tshuaj ntxiv.
Hematopoietic plab hnyuv siab raum
Cov tsos mob uas tsis tshua muaj tshwm sim: thrombocytopenia, pancytopenia. Cov mob uas tsis tshua muaj neeg mob: leukopenia, agranulocytosis, erythropenia, anmolytic anemia.
Nruab nrab hauv lub paj hlwb
Mob taub hau thiab kiv taub hau, pw tsaug zog, mob ntshav siab. Kev txhim kho ntawm lub tshuab pib thaum xub thawj yog kev sib zog tsis tuaj yeem, ua qhov tsis tuaj yeem tuav qoj ib ce, ua cawv, nqaij leeg, thiab txo qis ntawm kev tswj tus kheej.
Los ntawm ib sab ntawm cov metabolism
Qhov tsis tu ncua ntawm kev tshaib plab, tsaug zog thiab nkees, tawm hws ntau dhau, ua kom tsis muaj kev sib koom tes ntawm kev txav, hais lus tsis meej, paresis, tuag tes tuag taw, qhov hnyav nce sai.
Los ntawm lub cev tiv thaiv kab mob
Tsis tshua muaj: khaus ntawm daim tawv nqaij, tsos ntawm urticaria. Tsis tshua muaj neeg mob: kub taub hau, daj ntseg, kev txhim kho anaphylactic kev poob siab, qhov tsos ntawm vasculitis, mob pob txha.
Kev ua xua
Ua npaws, tawv nqaij sawv pob, ua xua ua xua ntawm qhov ua xua.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Ua rau muaj cov kev mob tshwm sim ib ntus los ntawm NS, tuaj yeem ua rau txo qis hauv kev xav thiab ua rau cov tshuaj tiv thaiv qeeb. Muab cov kev pheej hmoo txaus ntshai, nws raug nquahu kom tsis kam tsav tsheb thiab ua haujlwm nrog cov txheej txheem nyuaj rau lub sijhawm kho.
Cov lus qhia tshwj xeeb
Kev tsis noj sijhawm ntev los ntawm kev noj zaub mov, tsis muaj cov carbohydrates hauv zaub mov, kev qoj ib ce ntau dhau lawm tuaj yeem ua rau cov ntshav qab zib tsawg. Kev npog ntsej muag ntawm cov tsos mob ntawm cov ntshav qab zib tau pom tshwm sim thaum noj cov tshuaj no nrog cov tshuaj uas cuam tshuam rau hauv nruab nrab lub paj hlwb.
Kev tsis kam los ntawm kev tswj hwm qhov ncauj ntawm Maninil 5 nrog rau kev hloov pauv rau tshuaj insulin yog qhov yuav tsum tau ua tom qab kev phais mob, nyob rau hauv qhov muaj cov tawv nqaij ntau, qhov txhab, kub hnyiab, kis kab mob, nrog rau lub xeev febrile mob siab.
Siv rau lub sijhawm qub
Kev saib xyuas tshwj xeeb yuav tsum tau coj thiab ib qho kev xaiv cov tshuaj xaiv vim qhov muaj kev pheej hmoo siab ntshav qab zib.
Lub sij hawm nyob Maninila 5 cov me nyuam
Cov kev tshawb fawb soj ntsuam hauv chav kho mob yaus tsis tau ua. Muab cov kev pheej hmoo txaus ntshai, cov tshuaj tsis raug cai kom txog hnub nyoog 18 xyoo.
Siv thaum cev xeeb tub thiab lactation
Contraindicated vim muaj qhov txaus ntshai ntawm kev tsim cov tsis haum thiab cov teeb meem.
Daim ntawv thov rau lub raum khiav tsis zoo
Qhov tsawg kawg nkaus kev tswj hwm cov tshuaj yog tshuaj.
Siv rau lub siab ua haujlwm tsis zoo
Qhov tsawg kawg nkaus kev kho mob tau txais.
Noj ntau dhau ntawm Maninil 5
Kev siv ib zaug ntawm cov tshuaj ntawm lub siab ua rau cov tshuaj ua rau cov tsos ntawm cov tsos mob ntawm lub qog ntshav qab zib, cov hlab ntsha hlwb tsis sib haum, cuam tshuam kev xav. Kev qaug cawv hnyav ua rau poob ntawm kev tswj tus kheej, kev ua kom lub cev tsis ua pa tsis khov.
Overdose txoj kev kho - ib qho kev nkag sai sai ntawm cov zaub mov qab zib lossis dej, ib qho ua kom qab zib. Yog hais tias tus neeg mob poob nco qab - kev tswj hwm ntawm cov kua dej qab zib. Yog tias qaug cawv hnyav, yuav tsum tau saib xyuas ntau.
Kev cuam tshuam nrog lwm yam tshuaj
Siv cov tshuaj tsis haum nrog ACE inhibitors, anabolics, kev noj tshuaj ntawm coumarin derivatives, tetracyclines tsub kom cov kev kho mob uas muaj txiaj ntsig ntawm hypoglycemic tus neeg sawv cev.
Cov tshuaj tiv thaiv, tshuaj hormonal, barbiturates txo cov nyhuv hypoglycemic.
Tau tshaj Acarbose, insulin, Metformin.
Cawv tau zoo
Haus cawv tsis pub dhau. Ethanol ob leeg txo qis qis thiab nce cov nyhuv ntawm cov tshuaj.
Analogs
Cov tshuaj uas muaj qhov zoo sib xws hypoglycemic: Gliclada, Glian, Glimax, Glimed, Reklid, Perinel.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Daim ntawv yuav tshuaj yuav muag.
Nqe rau Maninil 5
Tus nqi pib ntawm 120 rubles. rau ib lub hwj los yog pob nrog cov hlwv nrog 120 ntsiav tshuaj.
Cia rau cov neeg mob rau cov tshuaj
Thaum sov li chav nyob.
Hnub tas sij hawm
3 xyoos
Chaw tsim tshuaj paus
Berlin-Chemie AG, Lub Tebchaws Yelemees.
Kev txheeb xyuas ntawm Maninil 5
Cov kws kho mob
Svetlana, 50 xyoo, Moscow, tus kws kho qhov muag endocrinologist: "Cov tshuaj txawv teb chaws no ntawm tus nqi pheej yig yog qhov cuab yeej zoo tshaj plaws rau kev txhawb nqa ntawm hom 2 mob ntshav qab zib mellitus.
Sergey, 41 xyoo, endocrinologist, Odessa: "Cov tshuaj hypoglycemic yog ib qho tshuaj zoo tshaj plaws hauv pawg tshuaj no. Nws tsis muaj yees, nws muaj kev tiv thaiv zoo los ntawm cov neeg mob thiab tuaj yeem siv ua prophylaxis hauv kev zam txim."
Lawj xeeb
Ksenia, 52, Barnaul: "Maninil 5 ntsiav tshuaj tau pab sai sai. Thaum cov piam thaj pib nce sai, cov tshuaj txo cov piam thaj 2 zaug hauv lub sijhawm luv luv. Kuv tsis muaj kev phiv dab tsi."
Gennady, hnub nyoog 42 xyoo, Minsk: "Tau ntev heev kuv tau nrhiav tshuaj uas tuaj yeem pab txo cov ntshav qab zib kom tsawg. Kuv tswj tau pom cov tshuaj no. "
Marianna, 32 xyoo, Irkutsk: "Qhov ntsuas pom qab zib poob ob zaug hauv ob peb hnub tom qab thov Maninil 5. Txhua yam kev noj qab haus huv kuj tau zoo dua. Kuv noj cov tshuaj nrog qhov kev kawm, tom qab so haujlwm. Kuv muaj peev xwm ua kom tau txais kev zam txim hauv ntau qhov kev kawm no."
