Ultrashort insulin Glulizin - cov yam ntxwv thiab cov yam ntxwv ntawm kev thov

Ntawm hom ntshav qab zib hom 1, tus neeg mob tuaj yeem siv cov kev siv tshuaj sai (sai), luv luv, nruab nrab, ua kom ntev thiab ua ntej tiv thaiv insulin.

Qhov twg yog qhov tau sau tshuaj rau kev noj tshuaj kom zoo txaus nyob ntawm tus neeg yam ntxwv ntawm lub cev. Yog tias xav tau insulin ultra-luv, Glulisin siv.

Luv luv txog insulin Glulizin

Cov tshuaj insulin

Cov tshuaj insulin yog qhov sib txig ntawm tib neeg cov tshuaj insulin, uas zoo sib xws hauv txoj ntsiab cai rau cov tshuaj no. Tab sis los ntawm xwm, nws ua tau nrawm dua thiab muaj cov qauv luv luv.

Glulisin tau nthuav tawm raws li kev daws teeb meem rau kev tswj hwm subcutaneous. Nws zoo li kua dej pob tshab tsis muaj impurities.

Cov npe lag luam rau cov tshuaj uas nws muaj: Apidra, Epidera, Apidra Solostar. Lub hom phiaj tseem ceeb ntawm cov tshuaj yog mus tswj cov metabolism hauv qabzib.

Raws li kev paub dhau los, qhov zoo thiab tsis zoo hauv qab no tuaj yeem sib txawv:

• ua nrawm dua li tib neeg hormone (+);
• zoo txaus siab qhov xav tau khoom noj hauv cov kua dej (+);
• peev xwm tsis muaj kev cuam tshuam ntawm cov nyhuv ntawm cov tshuaj ntawm cov piam thaj (-);
• siab zog - chav tsev txo cov suab thaj ntau dua li lwm cov insulins (+).

Cov chaw muag tshuaj thiab tshuaj pharmacokinetics

Tom qab kev tswj hwm subcutaneous, muaj ib qho txo ​​qis hauv qabzib vim qhov kev txhawb nqa ntawm nws cov cuab yeej siv hauv cov nqaij thiab kev tawm ntawm cov txheej txheem no hauv lub siab. Qhov kev txiav txim pib 10 feeb tom qab txhaj tshuaj.

Nrog kev qhia txog Glulisin thiab cov insulin tsis tu ncua ob peb feeb ua ntej noj mov, yav tas los ua kom zoo dua glycemic tswj tom qab noj mov. Lub bioavailability ntawm qhov paub zoo yog li 70%.

Kev sib txuas lus nrog cov protein ntshav yog qhov tsis zoo. Nws yog tawm me ntsis sai dua li niaj zaus kev txhaj tshuaj tib neeg. Ib nrab-lub neej ntawm 13,5 feeb.

Cov lus qhia rau kev siv

Cov tshuaj tau muab rau noj tam sim ntawd ua ntej noj mov (rau 10-15 feeb) lossis tam sim ntawd tom qab noj mov, noj rau hauv cov txheej txheem kev kho mob dav dav nrog lwm cov insulins (los ntawm lub sijhawm ntawm kev nqis tes lossis los ntawm keeb kwm). Txoj kev tswj hwm: subcutaneously hauv tus ncej puab, lub xub pwg. Txhawm rau kom tsis txhob raug mob, qhov chaw txhaj tshuaj yog zaws. Cov tshuaj raug muab tshuaj rau ntau qhov chaw, tab sis nyob hauv tib thaj chaw.

Glulisin koom ua ke nrog cov insulins thiab kab mob hauv qab no:

• nrog ib qho analog ntawm basal hormone;
• nrog nruab nrab;
• nrog ntev;
• nrog rau cov tshuaj hypoglycemic.

Lub zog ntawm glycemia nrog ntxiv ntawm insulin Glulizin rau kev kho nrog basal insulin

Yog tias txoj kev daws teeb meem yog xav siv cov koob txhaj koob txhaj tshuaj, kev txhaj tshuaj yog ua raws li cov lus qhia rau lub tshuab no. Cov ntau npaum ntawm cov tshuaj yog xaiv ib tus zuj zus, suav txog tus neeg mob tus mob thiab theem ntawm kev them nyiaj.

Ua ntej siv Glulizin, refilled hauv daim cartridge, kev tshuaj ntsuam xyuas yog nqa tawm - qhov av nkos nrog kev suav nrog tsis tsim nyog siv.

Video qhia siv kev xaum xim:

Kev ntsuas, phiv ntau tshaj, haus dej ntau dhau

Ib yam tshuaj raug xaj nyob rau qee yam hauv qab no:

• Ntshav Qab Zib Hom 1;
• Ntshav Qab Zib Hom 2;
• Mob ntshav qab zib hauv cov menyuam yaus txij li 6 xyoo.

Cov tshuaj tiv thaiv kom tsis txhob xaiv lub sijhawm tshuaj yog li nram qab no:

• ntshav tshuaj qis;
• kev tiv thaiv tsis txaus rau glulisin;
• hypersensitivity rau ntu ntu ntawm cov tshuaj.

Hauv chav kawm ntawm kev kho nrog tshuaj, phiv tshuaj tuaj yeem tshwm sim.

Qhov nquag ntawm cov xwm txheej tsis zoo hauv cov lej, qhov twg 4 yog qhov muaj ntau, 3 feem ntau, 2 yog tsawg, 1 tsawg tsawg:

Thaum lub caij noj tshuaj ntau dhau heev lawm, kuaj qhov pom ntshav qog ntshav qab zib. Nws tuaj yeem tshwm sim yuav luag tam sim ntawd lossis txhim kho maj mam.

Ua raws li kev siv cov tshuaj insulin ntau npaum li cas, lub sijhawm thiab qhov mob hnyav tshaj plaws, tus mob hypoglycemia yuav plooj ntau dua. Tus neeg mob yuav tsum txiav txim siab cov ntaub ntawv no txhawm rau txhawm rau tiv thaiv tus mob kom raws sijhawm. Txhawm rau ua qhov no, koj yuav tsum muaj qab zib (khaub noom, chocolate, ncuav qab zib ntshiab) nrog koj.

Nrog cov ntshav qog ua kom qis thiab qis me ntsis, cov khoom noj muaj suab thaj yog noj. Hauv cov mob hnyav, uas nrog nrog tsis nco qab, yuav tau txhaj tshuaj.

Kev tso tseg ntawm hypoglycemia tshwm sim nrog kev pab ntawm glucagon (s / c lossis i / m), kua nplaum (i / v). Hauv 3 hnub, tus neeg mob raug saib xyuas. Txhawm rau tiv thaiv kev txhim kho ntawm kev rov ua qog ntshav, nws yog ib qho tsim nyog yuav tsum tau noj cov carbohydrates tom qab ib ntus.

Yeeb tshuaj sib cuam tshuam

Thaum pib ntawm kev kho mob nrog ultrashort insulin, nws txoj kev cuam tshuam nrog lwm cov tshuaj noj tau coj los ua.

Ntau cov tshuaj tuaj yeem cuam tshuam cov metabolism hauv cov piam thaj, ua kom zoo dua lossis txo qis ntawm cov teebmeem ntawm kev tsim cov tshuaj insulin. Ua ntej kev kho mob, tus neeg mob yuav tsum tau qhia rau hauv kev tiv thaiv kom tsis txhob muaj qhov ua rau tsis pom zoo.

Cov tshuaj kho mob hauv qab no txhim kho cov nyhuv ntawm Glulisin: Fluoxetine, hypoglycemic agents hauv cov ntsiav tshuaj, tshwj xeeb, sulfonylureas, sulfonamides, salicylates, fibrates, ACE inhibitors, Disopyramide, MAO inhibitors, Pentoxifylline, Propoxifen.

Cov tshuaj hauv qab no txo ​​cov nyhuv ntawm kev kho mob insulin: atypical antipsychotics, sympathomimetics, tshuaj tiv thaiv qhov ncauj, cov thyroid hormones, glucagon, poj niam txiv neej cov tshuaj hormones, thiodiphenylamine, somatropin, diuretics, glucocorticosteroid tshuaj (GCS), proteinase inhibitors,

Pentamidine, beta-blockers, clonidine raug xa mus rau cov tshuaj uas tsis muaj kev cia siab tuaj yeem cuam tshuam lub zog ntawm Glulisin cov nyhuv thiab piam thaj (txo thiab nce ntxiv). Cawv muaj tib lub zog.

Kev xyuam xim tshwj xeeb yog pom thaum sau ntawv Pioglitazone rau cov neeg mob plawv. Thaum ua ke, cov xwm txheej ntawm kev loj hlob ntawm lub plawv nres tau qhia hauv cov neeg mob uas muaj lub siab xav ua tus mob no.

Yog tias kev kho mob nrog Pioglitazone tsis tuaj yeem raug tshem tawm, nws yog ib qhov tsim nyog los soj ntsuam tus mob. Yog tias ib qho kev mob plawv (qhov hnyav nce, o) tshwm sim, qhov kev siv ntawm cov tshuaj tau raug muab tso tseg.

Cov lus qhia tshwj xeeb

Tus neeg mob yuav tsum xav txog cov hauv qab no:

1. Nrog lub raum ua haujlwm lossis ua txhaum hauv lawv txoj haujlwm, xav tau cov tshuaj insulin yuav tsawg dua.
2. Nrog lub siab ua haujlwm ntawm lub siab, qhov xav tau kuj poob qis.
3. Vim tias tsis muaj cov ntaub ntawv, cov tshuaj tsis raug txwv rau cov menyuam yaus hnub nyoog qis dua 6 xyoo.
4. Siv nrog ceev faj nyob rau hauv cov poj niam cev xeeb tub nrog nquag saib xyuas ntawm ntsuas.
5. Thaum lub sijhawm lactation, koob tshuaj thiab kev noj haus kev kho mob yuav tsum muaj.
6. Thaum hloov mus rau Glulisin los ntawm lwm qhov tshuaj tiv thaiv vim muaj qhov tsis haum lub cev, kev ntsuas tshuaj tiv thaiv ua xua yuav tsum tau ua kom tsis txhob sib xyaw khaub thuas.

Tsuas tshuaj kho kom haum

Kev hloov kho koob tshuaj yog tau ua tiav thaum lub sij hawm hloov pauv los ntawm lwm hom kev txhaj tshuaj hormone. Thaum hloov tsheb los ntawm tsiaj insulin rau Glulisin, koob tshuaj feem ntau raug kho nyob rau hauv cov kev coj ua kom txo qis tom kawg. Qhov xav tau ntawm cov tshuaj tuaj yeem hloov nrog kev xav ntau dhau / kev tiv thaiv kev xav, thaum lub sijhawm sib kis tus kab mob.

Cov txheej txheem yog tswj hwm nrog kev pab ntawm ntsiav tshuaj hypoglycemic tshuaj. Yog tias koj hloov ib qho twg hauv cov phiaj xwm, koj yuav tau kho qhov tshuaj ntawm Glulisin.

Feem ntau ntawm hyperglycemia / hypoglycemia, cov tshuaj tiv thaiv kab mob hauv qab no yog qhov tau teev ua ntej hloov pauv kev noj tshuaj:

• cov txheej txheem thiab qhov chaw siv tshuaj yeeb tshuaj;
• nruj raws li cov txheej txheem kho;
• kev siv lwm cov tshuaj ntau lawm;
• psycho-txoj kev xav lub xeev.

Cov Ntaub Ntawv Ntxiv

Zoo - 2 xyoos

Txee lub neej tom qab qhib - lub hli

Cia - ntawm t ntawm +2 txog + 8ºC. Tsis khov!

Lub sijhawm so haujlwm yog mus tshuaj.

Glulisin yog qhov piv rau tib neeg cov tshuaj insulin:

• Insuman Sai Sai;
• Humulin;
• Neej Neeg Dab Tsi;
• Gensulin P;
• Vosulin P;
• Actrapid.

Glulisin yog yam tshuaj ultrashort rau kev tswj cov metabolism hauv qabzib. Nws yog tawm hauv kev sib xyaw nrog lwm cov insulins, coj mus rau hauv tus account lub phiaj xwm uas raug xaiv. Ua ntej siv, nws yog ib qho tseem ceeb kom kawm cov lus qhia tshwj xeeb thiab sib cuam tshuam nrog lwm yam tshuaj.