Muaj ntau cov tshuaj metabolism hauv kev cuam tshuam nrog cov rog thiab carbohydrate metabolism. Ib tus ntawm lawv yog Tiogamma.
Cov tshuaj no koom nrog cov txheej txheem metabolic tshwm sim hauv daim siab, pab txo qis cov roj cholesterol, nce glycogen ntau hauv nplooj siab, nquag cuam tshuam qhov tsis kam ntawm cov cell mus rau insulin thiab yog li pab txo qis ntshav qab zib, uas tseem ceeb heev rau ntshav qab zib (tshwj xeeb tshaj yog hom thib ob), thiab kuj tseem muaj cov khoom tiv thaiv antioxidant.
Nws yog qhov nyuaj rau tus txiv neej nteg kom to taub qhov Tiogamma yog los ntawm dab tsi thiab nws cov nyhuv yog dab tsi. Vim tias qhov tshwj xeeb muaj txiaj ntsig hauv lub cev, cov tshuaj tau muab tshuaj ua hepatoprotective, hypoglycemic, hypolipidemic thiab hypocholesterolemic tshuaj, nrog rau cov tshuaj uas txhim kho cov neurotrophic neurons.
Pharmacological kev txiav txim
Thiogamma belongs rau cov pab pawg metabolic ntawm cov tshuaj, cov tshuaj nquag hauv nws yog thioctic acid, uas nquag sib xyaw los ntawm lub cev thaum lub sijhawm oxidative decarboxylation ntawm alpha-ketone acids, yog ib qho kev ua kom muaj zog ua tsis txaus, ua cov coenzyme ntawm mitochondrial multienzyme complexes thiab cuam tshuam ncaj qha rau kev tsim ntawm lub zog ntawm lub cev.
Thioctic acid muaj feem cuam tshuam rau cov piam thaj, ua rau muaj kev tso tawm ntawm glycogen hauv daim siab, ntxiv rau txo qis cov tshuaj insulin nyob ntawm qib cellular. Yog hais tias kev sib txuas ntawm alpha-lipoic acid nyob rau hauv lub cev tsis txaus vim yog intoxication lossis tsub zuj zuj ntawm cov khoom lag luam qis (piv txwv li, lub cev ketone hauv cov kab mob ntshav qab zib ketosis), nrog rau ntau cov txuam nrog cov dawb radicals, ib qho kev ua tsis zoo hauv lub cev aerobic glycolysis tshwm sim.
Thioctic acid tshwm sim hauv lub cev hauv ob lub cev kev ua haujlwm thiab, raws li, ua hauv oxidizing thiab txo lub luag haujlwm, nthuav tawm cov tshuaj tiv thaiv antitoxic thiab antioxidant.
Thiogamma hauv kev daws thiab ntsiav tshuaj
Nws tau koom nrog hauv kev tswj hwm kev rog thiab carbohydrate metabolism. Ua tsaug rau hepatoprotective, antioxidant thiab antitoxic zoo, nws txhim kho thiab rov ua kom daim siab ua haujlwm.
Thioctic acid nyob rau hauv nws cov nyhuv pharmacological rau lub cev zoo ib yam li kev ua ntawm cov vitamins B. Nws txhim kho cov neurotrophic neurons thiab stimulates cov nqaij mos.
Pharmacokinetics ntawm Thiogamma yog raws li hauv qab no:
- thaum noj ntawm qhov ncauj, thioctic acid yuav luag tag thiab ncaj sai nqus los ntawm kev tso cai ntawm txoj hnyuv hauv plab. Nws yog tawm hauv daim ntawv ntawm metabolites los ntawm ob lub raum ntawm 80-90% ntawm cov tshuaj, metabolites yog tsim los ntawm oxidation ntawm sab saw thiab txuas, cov metabolism hauv cov kev sib koom ua ke, thiaj li hu ua "thawj tso cov nyhuv" los ntawm lub siab. Qhov siab tshaj plaws yog nce mus hauv 30-40 feeb. Bioavailability ncav cuag 30%. Ib nrab-lub neej yog 20-50 feeb, plasma tshem tawm yog 10-15 ml / min;
- thaum siv thioctic acid nyob rau hauv siab, qhov siab tshaj plaws tau pom tom qab 10-15 feeb thiab yog 25-38 μg / ml, thaj tsam ntawm qhov nkhaus-sijhawm nkhaus yog li 5 μg h / ml.
Yam khoom muaj sia
Cov tshuaj nquag ntawm cov tshuaj Tiogamma yog thioctic acid, uas yog pawg ntawm cov tshuaj tiv thaiv endogenous.
Hauv cov kev daws teeb meem, cov tshuaj nquag yog alpha lipoic acid nyob rau hauv daim ntawv ntawm meglumine ntsev.
Cov kev zam hauv cov ntsiav tshuaj ua qauv yog microcellulose, lactose, talc, colloidal silicon dioxide, hypromellose, sodium carboxyl methyl cellulose, magnesium stearate, macrogol 600, semethicone, sodium lauryl sulfate.
Hauv kev daws rau kev txhaj tshuaj, meglumine, macrogol 600 thiab dej rau txhaj tshuaj ua cov khoom siv ntxiv.
Daim ntawv tso tawm
Muaj ob peb hom tshuaj ntau npaum li cas raws li thioctic acid: coated ntsiav tshuaj, cov tshuaj muaj zog rau infusion, npaj txhij-ua cov qauv rau kev lis ntshav.
Kev sib xyaw cov tshuaj muaj los ntawm cov tuam ntxhab:
- daim ntawv ntsiav tshuaj raws li cov tshuaj nquag muaj 600 mg ntawm thioctic (lip-lipoic) acid. Cov ntsiav tshuaj yog tshuaj ntsiav-puab, npog nrog lub plhaub daj nrog lub ntsej muag dawb dawb. Ib lub ntsiav tshuaj ntawm txhua sab yog qhov muaj kev pheej hmoo;
- 1 ampoule ntawm 20 milliliters ntawm cov tshuaj zoo rau infusion ua cov tshuaj nquag muaj 1167,7 mg ntawm alpha-lipoic nyob rau hauv daim ntawv meglumine ntsev, uas sib haum rau 600 milligrams ntawm thioctic acid. Nws muaj cov tsos ntawm kev daws teeb meem ntawm lub hue ntsuab-daj;
- npaj txhij-ua txheem kev daws teeb meem rau Txoj kev lis ntshav hauv lub hwj ntawm 50 millilitres thiab muaj 1167.7 mg ntawm thioctic acid nyob rau hauv daim ntawv ntawm meglumine ntsev ua cov tshuaj nquag, uas sib haum rau 600 mg ntawm alpha lipoic. Cov tshuaj ntshiab tau muaj xim ntawm lub teeb daj mus rau ntsuab daj.
Tiogamma: dab tsi yog sau tseg?
Thiogamma belongs rau cov pab pawg ntawm endogenous metabolic npaj, koom nrog cov khoom noj carbohydrate thiab roj metabolism hauv qib cellular, pab txo qis cov ntshav qabzib, txhawb kev tsub zuj zuj ntawm glycogen nyob rau hauv daim siab, txo insulin tsis kam, muaj kev tshaj tawm antioxidant thiab antitoxic, muaj hepatoprotective, hypolipidemic thiab hypocholesteric effect Cov.
Vim tias nws cov yam ntxwv, cuam tshuam rau lub cev thiab cov txheej txheem hauv lub cev hauv lub cev tsis tu ncua, Thiogamma yog kho raws li kev kho mob tshuaj tiv thaiv nrog:
- mob ntshav qab zib polyneuropathy;
- cawv neuropathy;
- kab mob siab ntawm ntau yam etiologies, mob ntsws, daim siab rog;
- Thaum muaj tshuaj lom nrog cov khoom muaj kuab lom, nrog rau cov ntsev ntawm ntau yam hlau;
- nrog ntau yam ntawv ntawm intoxication.
Thiogamma muaj ntau qhov kev tiv thaiv tsis zoo, xws li kev tiv thaiv ib leeg tus kheej rau alpha lipoic acid, tsis muaj lactase, galactose intolerance.
Nws tsis tuaj yeem ua rau hauv lub xeev malabsorption, uas yog, tsis muaj peev xwm ua rau nqus galactase thiab qabzib los ntawm cov hnyuv, hauv kev mob plawv thiab ua pa tsis ua haujlwm, myocardial infarction, mob plawv tsis txaus, tsis ua haujlwm rau lub hlwb, lub raum tsis ua haujlwm, lub cev qhuav dej, mob cawv, thiab lwm yam kab mob thiab cov xwm txheej uas ua rau cov kab mob lactic acidosis.
Thaum siv Thiogamma, xeev siab, kiv taub hau, ntuav, raws plab, mob plab, tawm hws ntau dhau, ua xua nyob rau hauv daim ntawv ua pob ntawm daim tawv nqaij, mob ntshav qab zib yog qhov ua tau, vim tias siv cov ntshav ntawm lub suab nrawm.
Tsis tshua muaj kev nyuaj siab ua pa nyuaj thiab anaphylactic kev poob siab.
Thaum siv Tiogamma, cov neeg muaj ntshav qab zib yuav tsum ua kom muaj kev tswj hwm cov ntshav qab zib kom ntau, txij li thioctic acid nce lub sijhawm ntawm kev siv cov kua nplaum, uas, thaum nws qib poob qis, tuaj yeem ua rau poob siab hypoglycemic.
Nrog rau qab zib sai sai, tshwj xeeb tshaj yog nyob rau theem pib ntawm kev noj Thiogamma, qee zaum yuav tsum tau txo cov tshuaj insulin lossis hypoglycemic kom tsawg dua. Kev siv dej cawv thiab tshuaj muaj cawv yog txwv tsis pub siv thaum lub sijhawm Tiogamma, vim tias qhov kev kho mob txo qis, thiab muaj kev cuam tshuam loj heev ntawm cov dej cawv uas muaj dej cawv tuaj yeem tshwm sim.
Alpha-lipoic acid tsis sib xws nrog kev npaj muaj dextrose, Ringer-Locke daws, cisplatin thaum siv ua ke. Nws kuj txo qhov ua tau zoo ntawm kev npaj muaj hlau thiab lwm yam hlau.
Nqi
Thiogamma yog ua nyob hauv lub teb chaws Yelemees, tus nqi nruab nrab yog:
- rau kev ntim ntawm cov ntsiav tshuaj ntawm 600 mg (60 ntsiav tshuaj ib pob) - 1535 rubles;
- rau kev ntim ntawm cov ntsiav tshuaj ntawm 600 mg (30 daim ib pob) - 750 rubles;
- rau kev daws rau kev lis ntshav ntawm 12 ml / ml hauv 50 ml vials (10 daim) - 1656 rubles;
- ib qho kev daws teeb meem rau Txoj kev lis ntshav 12 ml / ml lub raj mis ntawm 50 ml - 200 rubles.
Related videos
Ntawm kev siv alpha lipoic rau cov ntshav qab zib hauv kev yees duab:
Cov lus piav qhia txog hom tshuaj Thiogamma no yog ib qho kev qhia ua ke thiab tsis tuaj yeem siv ua cov lus qhia. Yog li, ua ntej koj yuav thiab siv nws ntawm koj tus kheej, koj yuav tsum sab laj tus kws kho mob uas yuav txawj xaiv txoj kev kho mob uas tsim nyog thiab ntau npaum li cas ntawm cov tshuaj no.
