Niaj hnub no, kab mob plawv yog thawj zaug ntawm cov kab mob uas ua rau tib neeg tuag. Feem ntau cov feem ntau, qhov kev ua txhaum provokes atherosclerosis, uas yog tsim vim muaj cov txuam nrog cov roj (cholesterol) phem thiab cov plahaum tsis zoo hauv lub cev.
Txhawm rau kom zam dhau qhov mob ntshav qab zib hnyav, nws yog ib qho tseem ceeb kom pib kho kom ncav sijhawm. Tom qab tshuaj ntsuam thiab txheeb xyuas, tus kws kho mob uas tuaj koom yuav qhia koj txog yam twg rau cov roj (cholesterol) uas ua hauj lwm zoo tshaj plaws thiab nyab xeeb.
Cov tshuaj txwv lub siab ua kom lub siab, tawm dag ntxiv kom tsis txhob muaj cov lipids teeb meem hauv cov ntshav, ntxuav cov hlab ntshav thiab txhim kho lub neej ntawm tus neeg mob.
Hom tshuaj
Statins tuaj yeem yog ntuj thiab hluavtaws, tsim ntawm lub zog. Tsis tas li, cov roj (cholesterol) tau muab faib ua plaub tiam.
Thawj cov tshuaj suav nrog rau ntuj tsim, uas cais tawm ntawm cov hu ua fungi. Cov tshuaj ntawm cov cim ntxiv tseem tsim los ntawm kev nthuav tawm hluavtaws.
Simvastatin thiab Lovastatin yog thawj-tiam siv. Lawv muaj kev tawm suab tsawg tshaj tawm thiab ua rau muaj kev cuam tshuam ntau yam. Kev siv ntev dua yuav tsum tau siv cov tshuaj thib ob, uas suav nrog fluvastatin. Lawv tuaj yeem muab khaws cia rau hauv tib neeg cov ntshav kom ntev.
Cov tshuaj thib peb ua rau txo qis tseem ceeb nyob rau hauv kev txiav txim ntawm triglycerides thiab qis lipoproteins, uas Atorvastatin pom tias yog qhov nrov tshaj plaws. Kev npaj rau tsa cov roj (cholesterol) hauv qib plaub tshiab tau pab txhawb kom muaj txiaj ntsig thiab nyab xeeb ntxiv, piv nrog cov piv txwv ua ntej.
Ntxiv nrog rau cov haujlwm yooj yim ntawm kev txo qis lipid, cov tshuaj muaj cov cim tshwj xeeb thiab cov txiaj ntsig ntxiv.
Statin khoom
Cov tshuaj ntawm statin pawg cuam tshuam rau kev tsim cov cholesterol los ntawm daim siab los ntawm nws cov kev txwv. Qhov no tshwm sim vim qhov tseeb tias cov enzymes koom nrog hauv cov synthesis ntawm cov roj cholesterol yog txhaws. Cov enzymes leeb tsim cov mevalonic acid, uas ua lub zog ua ntej ntawm cov roj (cholesterol).
Statins tseem cuam tshuam rau endothelium ntawm cov hlab ntshav, txo kev mob ntshav thiab txo qhov kev pheej hmoo ntawm cov ntshav txhaws, txhawb kev sib txuas ntawm nitric oxide, uas ceev thiab txo cov hlab ntsha, tswj kev ruaj ntseg ntawm cov tshuaj lom neeg muaj pes tsawg leeg ntawm cov ntshav.
Tsis tas li ntawd, cov tshuaj tiv thaiv myocardial infarction. Yog li, piv txwv li, Rosuvastatin tau ua pov thawj los ua ib qho txiaj ntsig zoo hauv kev txo qis kev pheej hmoo ntawm kev txhim kho cov hlab plawv pathologies. Hauv lub sijhawm rov kho dua tom qab lub plawv nres, nws yog statins uas tau coj mus, txij li lawv pab cuam kho kom sai.
Xws li cov ntsiav tshuaj tuaj yeem nce qib ntawm cov lipids zoo.
Cov txiaj ntsig ntawm statins
Cov tshuaj no yog siv rau kev tiv thaiv thiab kho atherosclerosis, thaum lwm txoj kev kho tsis tau qhia cov nyhuv xav tau. Statins txo txoj kev pheej hmoo ntawm lub plawv nres, ntu ischemic nres, mob stroke, atherosclerosis.
Tsis tas li, cov ntsiav tshuaj normalize kev ua haujlwm ntawm lub plawv ntawm cov hlab ntshav hauv lub plawv thiab angina pectoris, nres cov tsos mob ntshav qab zib, txo qhov hnyav hauv kev rog, thiab txo qhov mob ntawm cov phab ntsa ntawm cov hlab ntsha. Cov tshuaj tuaj yeem ua rau cov ntshav khov thiab tiv thaiv kev txhim kho ntawm thrombosis, ua kom lub cev tsis ua haujlwm zoo ntxiv, nthuav tawm cov hlab ntsha, thiab tshem tawm cov plaques atherosclerotic.
Cov tshuaj tso cai rau koj kom leeb kev kho dua tshiab nrog stenting, ischemic stroke, mob hlab ntsha o bypass grafting, angioplasty, myocardial infarction, pulmonary embolism.
Leej twg contraindicated nrog kev kho mob statin
Ua ntej pib txoj kev kho mob, koj yuav tsum sab laj nrog kws kho mob. Nws yuav pab koj xaiv cov tshuaj thiab ntau npaum li cas, noj mus rau hauv tus account tus yam ntxwv ntawm lub cev thiab qhov muaj cov kabmob me. Txij li thaum satins muaj ntau txoj kev sib tiv, kev siv tshuaj tus kheej yuav tsum tsis txhob ua.
Kev siv cov tshuaj yuav tsum tau tso pov tseg tag nrho thaum muaj kev fab tshuaj thiab tsis haum rau cov tshuaj yeeb tshuaj, mob raum, cuam tshuam cov thyroid caj pas thiab endocrine system.
Tsis tas li, cov ntsiav tshuaj tsis tuaj yeem siv rau thaum muaj kev ua txhaum ntawm cov leeg ua haujlwm, mob siab thiab mob siab daim siab. Hauv cov ntshav qab zib mellitus, tshwj xeeb yuav tsum tau saib xyuas thaum xaiv txoj hauv kev txo cov roj (cholesterol). Thaum cev xeeb tub, cov tshuaj yuav cuam tshuam rau lub plab hauv plab, yog li nws yog qhov zoo dua los hloov cov tshuaj nrog txoj hauv kev nyab xeeb lossis kev txiav tawm tag nrho kev kho mob.
Koj yuav tsum nkag siab tias kev noj tshuaj pab tuaj yeem ua rau muaj kev mob tshwm sim.
- Hauv qee qhov tsis tshua muaj tshwm sim, myopathy tshwm sim. Qhov kev ua txhaum cai no nyob ntawm lub hnub nyoog ntawm tus neeg mob, koob tshuaj, muaj cov tsos mob hnyav ntawm ntshav qab zib.
- Qee lub sijhawm ua haujlwm ntawm lub hauv nruab nrab cov hlab ntsha tsis kam. Qhov no nws nthuav qhia nws tus kheej hauv daim ntawv ntawm mob taub hau, kiv taub hau, pw tsaug zog, dav dav tsis muaj zog.
- Thaum kis tus kab mob ua pa rau qee kis, rhinitis, mob ntsws txhaws taus.
- Tsis tas li, tus neeg mob tuaj yeem hnov xeev siab, ntuav, cem quav.
Feem ntau, nrog kev ua kom zoo, ceev faj thiab tsim nyog ntawm cov ntsiav tshuaj, koj tuaj yeem pom qhov ua tau zoo. Tab sis yog tias muaj kev siv tshuaj ntau dhau thiab siv lub caij nyoog ntev, tus neeg mob yuav muaj qhov tsis zoo tshwm sim los ntawm:
- Mob hauv lub plab thiab plab hnyuv me, cem quav, ntuav;
- Amnesia, insomnia, paresthesia, kiv taub hau;
- Thrombocytopenia lossis txo qis hauv cov platelet xav tau
- O o, rog dhau, impotence rau tus txiv neej;
- Mob leeg, mob nraub qaum, mob caj dab, mob myopathy.
Tsis tas li ntawd, ib qho zoo tshaj plaws tsis tuaj yeem pom muaj yog tias hypolipidemic thiab lwm yam tshuaj siv tsis txuam nrog ntxiv siv.
Qhov zoo thiab qhov tsis zoo ntawm statins
Yog tias koj niaj hnub kho thiab ua raws li txhua cov lus qhia kho mob, pawg tshuaj no txo kev phom sij los ntawm kev mob plawv thiab mob stroke 40 feem pua. Cov tshuaj muaj peev xwm txo cov kev tsis txaus ntawm cov roj (cholesterol) hauv cov ntshav los ntawm 50 feem pua. Txhawm rau ntsuas tus mob, nws raug nquahu ib hlis ib zaug los pub ntshav mus txog qib uas muaj teeb meem lipids.
Qhov no yog tshuaj nyab xeeb, uas, muab tshuaj rau, tsis muaj tshuaj lom rau hauv lub cev. Cov tshuaj tsim tshiab muaj qhov tsawg tsawg ntawm cov kev mob tshwm sim thiab, tsis muaj lub txim, tso cai kho mob ntshav qab zib. Niaj hnub no, muaj ntau yam duab yeeb yam rau kev muag ntawm tus nqi pheej yig, yog li txhua tus tuaj yeem xaiv tshuaj, tsom mus rau lawv cov peev nyiaj.
Qhov kev tsis zoo suav nrog tus nqi siab, cov kev npaj qub Rosucard, Krestor, Leskol Forte tshwj xeeb tshaj yog kim.
Tab sis nyob rau hauv txee muaj yeej ib txwm ntsiav tshuaj pheej yig dua, uas tej zaum yuav muaj tib lub active active tshuaj.
Txoj cai zoo tshaj plaws thiab nyab xeeb
Txhawm rau teb cov lus nug ntawm dab tsi statins tuaj yeem txhim kho tus neeg mob yam tsis muaj kev phom sij rau kev noj qab haus huv, kev tshawb fawb tshawb fawb tau tshawb fawb tau lawm. Raws li qhov tshwm sim, nws tau muab tawm tias qhov muaj txiaj ntsig zoo tshaj plaws thiab tsis tshua muaj tshuaj Atorvastatin. Nyob rau hauv thib ob qhov chaw yog tsis muaj tsawg dua txhim khu kev qha thiab siv tau Rosuvastatin, thiab hauv peb - Simvastatin.
Tus kws kho mob tuaj yeem sau tshuaj atorvastatin rau cov kab mob ntawm cov kab mob hlab plawv thiab ntshav muaj roj. Cov tshuaj no tau ua pov thawj nws tus kheej hauv ntau cov kev tshawb fawb hauv kev kho mob thiab hauv kev coj ua tau muaj pov thawj tias nws tuaj yeem txo tus mob stroke 50 feem pua. Raws li tus kws kho mob cov lus pov thawj, qhov kev siv tshuaj yog 40-80 mg thaum sawv ntxov lossis yav tsaus ntuj, nyob ntawm seb qhov mob hnyav npaum li cas.
Rosuvastatin yog ib qho tshuaj tsim artificially. Nws muaj cov ntsiab lus ntawm hydrophilic, uas ua rau txo qis kev phiv thiab nres ntawm cov roj (cholesterol) phem. Tsis zoo li lwm cov tshuaj, cov tshuaj tsis ua rau mob myopathy thiab mob ib ce.
- Ib koob tshuaj ntawm 40 mg txo cov theem ntawm tsawg lipoproteins tsawg los ntawm 40 feem pua thiab nce qhov concentration ntawm cov roj (cholesterol) zoo los ntawm 10 feem pua.
- Qhov tshwm sim los ntawm kev siv tshuaj tuaj yeem pom tau twb dhau xya hnub, tom qab ib hlis cov nyhuv nce mus txog nws qhov siab tshaj plaws, thiab cov mob no tuaj yeem tswj hwm ntev.
Simvastatin tuaj yeem txo qhov kev pheej hmoo ntawm kev tsim mob vascular thiab kab mob plawv los ntawm 10 feem pua tom qab lub plawv nres, mob ntshav nce hlwb, thiab ntshav qab zib. Yog tias koj noj cov tshuaj mus ntev, koj tuaj yeem kho qhov feem ntawm qhov tsis zoo thiab roj (cholesterol) zoo, txo cov kev pheej hmoo ntawm cov hlab ntshav ntawm cov hlab ntshav thrombosis.
Raws li kws kho mob sau tseg hauv lawv txoj kev ntsuam xyuas, statins yog tshuaj muaj kev nyab xeeb. Tab sis nws yog ib qho tseem ceeb yuav tsum tau nyeem cov lus qhia ua ntej siv, coj mus rau hauv tus kheej tus yam ntxwv ntawm lub cev, nruj me ntsis ua raws kev noj tshuaj, kev ceeb toom ceev faj thaum muaj cov kab mob me thiab tsis txhob siv tshuaj rau tus kheej.
Txhawm rau txhim kho cov teeb meem dav dav, nws pom zoo kom brew decoctions ntawm tshuaj ntsuab tshuaj, suav nrog cov khoom noj cog hauv cov zaub mov, thiab siv cov zaub mov kom huv thaum lub sijhawm ua noj.
Cov tshuaj zoo sib xws
Txhua ntawm cov tshuaj saum toj no muaj lub npe lag luam sib txawv. Yog li ntawd, tus kws kho mob tuaj koom tuaj yeem sau ib qho khoom zoo ib yam los yog, hloov pauv, cov tshuaj hluavtaws ntawm tus nqi zoo dua.
Cov tshuaj nquag ntawm Simvastatin yog lub ntsiab lus zoo uas muaj cov roj lipid-txo cov nyhuv. Cov npe ntawm cov analogues suav nrog Zovatin, Arieskor, Simvakor, Simgal, Vasilip, Zosta, Zokar, Simvastol, Vastatin.
Cov tshuaj ntawm thawj tiam Pravastatin tuaj yeem hloov los ntawm Pravospres, Lipostat. Lovastatin-based statins suav nrog Mevacor, Lovagexal, Lovacor, Apextatin, Rovacor, Holetar, Cardiostatin, Medostatin, Lovasterol, Liprox.
Cov tshuaj Atorvastatin suav nrog Tulip, Canon, Atoris, Atorvox, Atomax, Lipitor, Liprimar, Torvakard, Anvistat, Liptonorm. Tsis muaj ib qho tsawg dua thiab siv tshuaj tiv thaiv zoo ntawm Rosuvastatin rau kev txo cov ntshav roj yog Rosart, Rosulip, Roxera, Krestor, Tevastor, Mertenil, Novostatin, Akorta.
Statins tau piav qhia hauv daim video hauv kab lus no.
