Insuman Bazal: cov lus qhia rau kev siv, analogues, tus nqi

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Kev kho cov piam thaj hauv cov ntshav ntawm tus neeg mob ntshav qab zib yuav tsum ua ntu zus. Qhov no yuav tsum muaj cov kev tswj hwm tas mus li, thiab ntau zaus ntxiv rau kev txhaj tshuaj, ntawm cov tshuaj hypoglycemic. Kom yooj yim dua, cov neeg mob tau hais kom siv tshuaj nyob hauv cov phwj tshwj xeeb.

Cov cuab yeej no tso cai rau koj noj cov tshuaj uas xav tau, nrog rau kev yooj yim hauv kev thauj mus los thiab siv. Cov kev txhaj tshuaj no yuav luag tsis muaj mob.

Txhawm rau kom nkag siab zoo, nws yog ib qho tsim nyog yuav tsum paub tias yam tshuaj twg tuaj yeem siv hauv txoj hauv kev no. Ib qho ntawm cov tshuaj feem ntau cov piam thaj txo qis yog Insuman Bazal GT. Cov tshuaj no yog qhia los ntawm cov khoom cua ntawm cov tshuaj hormones - tib neeg insulin.

Insuman Bazal muaj lub sijhawm nruab nrab ntawm kev ua uas tshwm sim ib teev tom qab kev siv tshuaj. Cov khoom xyaw tseem ceeb zoo ib yam rau tib neeg cov insulin yog nruab nrab Hagedorn protamine (isofan insulin protamine).

Cov tshuaj no tau tsim rov qab rau hauv lub forties los ntawm cov kws tshawb fawb Canadian. Lub sijhawm ua haujlwm ntawm cov tshuaj insulin yog ua tiav los ntawm kev ntxiv rau nws ib qho protein tshwj xeeb - tshuaj lom neeg. Ua tsaug rau nws, nrog kev qhia ntawm cov tshuaj daws teeb meem, txhaws ntawm lub lymphatic hlab ntsha thiab ntshav ntshav microvessels loj hlob, uas txo qis kev nqus ntawm cov tshuaj mus rau hauv cov hlab ntshav.

Tsis tas li ntawd, qhov sib ntxiv ntawm zinc ions mus rau qhov sib tov sib xyaw ua kom lub zog ruaj khov rau cov tshuaj thiab tso cai rau koj kom txo qis kev ua ntawm cov tshuaj insulin rau hauv lub sijhawm 72 teev.

Kev Sau ua ke thiab daim ntawv ntawm kev tso tawm

Qhov tshuaj insulin muaj nyob hauv peb hom:

  1. Ntim rau hauv tsib lub vials, txhua tsib milliliters;
  2. Ib lub raj mis rau kaum millilitis;
  3. Cartridges rau peb milliliters, rau koob txhaj tshuaj sau. Txhua lub cartridge muaj tshuaj ntsiav nrog 1 ml ntawm cov tshuaj nquag.

Cartridges yog qhov nrov tshaj plaws, vim tias lawv hloov pauv tsis nyuaj, thiab kev siv rab koob xaum xim yog qhov yooj yim thiab yuav luag tsis mob.

Hauv txhua lub raj mis los yog daim cartridge, hauv 1 milliliter ntawm cov tshuaj yog li 100 IU ntawm cov tshuaj insulin.

Cov tshuaj muaj suab thaj no muaj:

  • Tib neeg cov tshuaj insulin - yog cov khoom siv tseem ceeb, nws yog ib qho tsim nyog yuav tsum tau ua tib zoo saib xyuas cov tshuaj noj, txhawm rau kom tsis txhob noj tshuaj ntau dhau lossis tsis txaus siv cov tshuaj insulin, uas yuav ua rau muaj kev cuam tshuam;
  • M-cresol - nyob rau hauv qhov kev npaj no muaj nyob hauv tus nqi tsis txaus, ua lub luag haujlwm ntawm cov kuab tshuaj rau cov khoom ntxiv, thiab tseem ua cov tshuaj tua kab mob zoo;
  • Phenol - cov kua qaub no ua cov tshuaj tua kab mob, tus nqi me me nyob rau hauv cov tshuaj no. Ua ke nrog m-cresol, nws tso cai rau koj kom tswj hwm lub xeev tsis huv ntawm cov tshuaj, uas yuav tiv thaiv tus neeg mob los ntawm kev kis kab mob;
  • Protamine sulfate - ua haujlwm txuas rau cov tshuaj insulin, uas tso cai rau koj ua kom nws lub cev ntev mus ntev. Tsis tas li, cov tshuaj yeeb no tuaj yeem thaiv lub lumen ntawm cov hlab ntsha, uas cuam tshuam rau qhov nqus ntawm qhov tshuaj txhaj tshuaj;
  • Sodium dihydrogen phosphate - ua raws li qhov tsis haum, ntxiv cov dej-tuav cov khoom rau cov khoom qhia. Nws yog ib qho tsim nyog yuav tsum ncua sijhawm ntawm kev nqus ntawm cov tshuaj insulin rau hauv cov ntshav;
  • Hydrochloric acid - tswj cov kua qaub ntawm cov tshuaj no.

Pharmacodynamics thiab pharmacokinetics

Cov tshuaj no yog ib qho kev sib txuas ntawm tib neeg cov tshuaj insulin, tsuas yog nrog kev sib ntxiv ntawm cov tshuaj uas cuam tshuam rau kev nqus thiab lub sijhawm ua.

Cov khoom muaj suab thaj txo qis ntawm Insuman Bazal tau tiav ua tsaug rau:

  1. Txhawm rau nrawm rau qhov tsis muaj qab zib ntawm cov piam thaj hauv lub cev - thaum lub zog ua rau lub cev tsis muaj zog tiv thaiv kev nqus ntawm carbohydrates nyob rau hauv lub plab zom mov, nrog rau kev ua kom muaj zog ntxiv ntawm cov ntshav qab zib los ntawm lub raum;
  2. Qhov nqus ntawm cov piam thaj los ntawm cov ntaub so ntswg ntawm lub cev nce - vim tias, feem ntau ntawm cov piam thaj nkag mus rau cov ntaub so ntswg thiab cov hlwb ntawm lub cev, vim tias nws cov ntsiab lus hauv cov ntshav txo qis;
  3. Kev nrawm nrawm ntawm liponeogenesis - cov cuab yeej no ua rau lub cev muaj roj hauv lub cev, vim tias cov roj carbohydrates hauv cov hlab ntsha tau hloov pauv hauv cov khoom nruab nrog sab hauv. Thiab cov txiaj ntsig metabolite tau tso rau hauv cov nqaij mos, qhov nqaij ntawm lub cev, cov leeg nqaij thiab lwm cov nqaij yog cov rog;
  4. Kev loj hlob ntawm glyconeogenesis - qhov no, ib qho tshwj xeeb rau cov piam thaj yog tsim, uas yog cov tshuaj polysaccharide nyuaj. Nrog rau qhov tsis muaj cov piam thaj hauv cov ntshav, cov polysaccharide no yuav tawg ua rau nws qib hauv cov ntshav;
  5. Txo cov ntshav qabzib synthesis los ntawm lub siab - hauv lub siab muaj cov metabolism ntawm ntau cov carbohydrates, cov rog thiab txawm tias cov protein, uas nyob hauv qab ntawm cov enzymes tshwj xeeb tuaj yeem tsim cov piam thaj;
  6. Kev tsim cov tshuaj insulin - qhov nyuaj no yog nyob ntawm daim nyias nyias ntawm lub cev ntawm lub cev, thiab nce ntawm kev tso cov piam thaj hauv sab hauv, uas txo nws cov concentration hauv cov ntshav thiab ua rau muaj kev cuam tshuam ntau dua ntawm cov cell. Cov nyhuv no tau ua tiav tau zoo los ntawm cov neeg ncaws pob uas xav ua kom tau txais txiaj ntsig zoo dua yog siv insulin.

Ua raws li cov lus qhia rau kev siv, Insuman Bazal, nws yuav tsum raug tswj hwm subcutaneouslyCov. Qhov no yog qhov tsim nyog kom tsis txhob muaj qhov nce ntxiv hauv kev tsim nyog ntawm cov tshuaj insulin hauv cov ntshav. Yog li, koj yuav tsum tswj hwm lub sijhawm ntawm kev tswj hwm thiab xam lub sijhawm ntawm kev txhaj tshuaj ntxiv, vim hais tias cov nyhuv ntawm cov tshuaj tau tiav 1-2 teev tom qab kev tswj hwm, thiab cov txiaj ntsig tshaj plaws pom txog 20-24 teev.

Cov Khoom Qhia

Cov tshuaj no yog siv hauv kev txhim kho cov tshuaj insulin-tiv thaiv ntshav qab zib mellitus ntawm thawj hom. Tseeb, nrog rau qhov sib txawv ntawm tus kab mob no, qhov txo qis hauv kev tsim ntawm cov tshuaj insulin los ntawm Langerhans hlwb hauv cov txiav yog pom, uas yuav tsum siv kev hloov kho.

Cov tshuaj no yog siv los ua kev kho mob ntev ntev, nws tuaj yeem txuas nrog cov tshuaj insulin sai sai Insuman Rapid.

Tseem Ceeb! Tsis tas yuav muab cov tshuaj no sib xyaw nrog lwm tus kab mob hypoglycemic, rau kev tswj hwm tib lub sijhawm, kev txhim kho ntawm qhov tsis xav tsis haum yog ua tau. Ntxiv mus, yog tias siv ntau hom tshuaj qab zib rau cov ntshav qab zib, nws yuav tsum siv cov kua ntswg ib leeg lossis cov xaum xaum rau txhua qhov tshuaj cais.

Tsuas tshuaj

Siv Insuman Bazal GT hauv cov koob txhaj tshuaj lossis nrog insulin koob txhaj tshuaj, nws yog qhov tsim nyog los ua haujlwm nrog koj tus kws kho mob. Hauv qhov no, thawj qhov kev lees txais yuav tsum tau nyob hauv tsev kho mob los ntawm kev saib xyuas ntawm tus kws tshaj lij. Nws yuav pab tswj cov tshuaj uas yuav tsum tau ntawm insulin, tswj kev qhia ntawm kev siv tshuaj txhua hnub, zoo li soj ntsuam lub cev lub cev rau cov kev kho no.

Tsis muaj ntau qhov koob tshuaj rau kev siv cov tshuaj no, txij li ib qho tshuaj twg raug xaiv rau txhua tus neeg mob. Qhov koob tshuaj txhua hnub yog xam raws qhov hnyav ntawm lub cev thiab yog 0.4-1.0 U / kg.

Thaum xam xyuas qhov ntau npaum li cas, nws yog qhov yuav tsum tau txiav txim siab seb tus neeg mob ua raws li cov kev cai noj haus, uas ua rau lub neej muaj sia, nws cov haujlwm ib hnub. Cov tshuaj no yuav tsum raug tswj hwm nruj me ntsis subcutaneously. Qhov yuav tsum tau ua ntej yog hloov chaw txhaj tshuaj. Qhov no yog qhov tsim nyog vim tias muaj kev tshwj xeeb hauv cheeb tsam ntawm cov tshuaj, thiab kev tiv thaiv ntawm kev txhim kho cov ntaub so ntswg kev puas tsuaj thiab necrosis nrog rau kev tswj hwm ntawm cov tshuaj.

Qhov kev ua no yuav tsum muaj kev sib koom tes nrog tus kws kho mob uas koom nrog. Txij li thaum qhov sib txawv ntawm lub cev muaj qib sib txawv ntawm txoj kev loj hlob ntawm lub network ntawm cov ntshav thiab cov hlab ntsha, vim qhov no, feem ntawm cov tshuaj insulin nkag mus rau hauv cov hlab ntshav tuaj yeem hloov pauv.

Tus kws kho mob yuav tsum xav txog seb cov piam thaj puas hloov pauv thaum Insuman siv los ntawm ntau qhov chaw txhaj tshuaj.

Thaum siv Insuman Bazal, cov yam ntxwv hauv qab no yuav tsum raug xam tias:

  • Thaj chaw ntawm kev taw qhia;
  • Hloov lub cev qhov hnyav - nrog ib qho kev nce ntxiv, qhov ntau ntxiv nce ntxiv, qhov no cov ntaub so ntswg tiv thaiv cov tshuaj insulin kuj yuav tshwm sim, nce siab ntxiv nyob rau hauv cov piam thaj thiab kev tsim cov davhlau ya nyob twg;
  • Kev hloov pauv ntawm kev noj haus thiab kev ua neej - kev noj haus rau ntshav qab zib yog tswj xyuas cov ntshav qab zib kom tsis tu ncua, nyob rau hauv kev pauv hloov ntawm cov khoom noj khoom haus lossis hloov cov zaub mov li ib txwm, cov tshuaj tsim nyog yuav tsum tau rov ua dua. Cov kev coj ua no yuav tsum tau nqa tawm tom qab hloov lawv txoj kev ua neej, qee kis, cov neeg mob xav tau cov tshuaj insulin tsawg dua (cov duab ua haujlwm), thiab qee qhov, kev noj tshuaj ntau (mob, txo qis kev ua haujlwm);
  • Hloov mus rau tib neeg cov kua dej los ntawm ib tus tsiaj - xws li qhov kev tshwm sim tsuas yog nyob hauv kev saib xyuas ntawm tus kws kho mob uas tuaj koom, tsuas yog nws yuav tsum kho cov koob tshuaj. Hauv cov neeg mob ntshav qab zib, muaj qhov nce siab ntxiv rau tib neeg cov insulin, yog li feem ntau cov tshuaj ntawm cov tshuaj txo qis.

Nrog rau kev txhim kho cov kabmob nrog rau lub siab ua haujlwm lossis ua rau nws, kev tswj cov kua nplaum yuav tsum tau nqa tawm, thiab kev noj cov suab thaj ntawm cov tshuaj txo cov tshuaj noj yuav tsum tau ua kom tsawg. Txij thaum cov tshuaj insulin txo qis, ntxiv rau cov kua nplaum ua ke nyob rau hauv lub siab.

Nws tseem yog yuav tsum tau kho cov koob tshuaj nrog kev txhim kho ntawm lub raum tsis ua haujlwm, uas nrog cov lus qhia ntawm cov koob tshuaj ib txwm muaj peev xwm ua rau lub qog ntshav qab zib.

Kev tiv thaiv kev nyab xeeb

Ua ntej hu ncaj qha rau cov tshuaj, koj yuav tsum xyuas kom meej nws zoo. Txhawm rau ua qhov no, koj yuav tsum tau nqa lub raj mis, thiab nco ntsoov tias muaj lub hau yas uas hais tias nws tsis tau qhib. Tom qab ntawd ntsuas xyuas qhov xwm txheej ntawm cov tshuaj tiv thaiv nws tus kheej.

Nws yuav tsum yog xim dawb, opaque, xwm yeem. Yog tias nag lossis daus, muaj cov flakes, qhov pom tseeb ntawm kev ncua nws tus kheej tau pom, qhov no qhia qhov tsis zoo ntawm cov tshuaj.

Ua ntej hu, kev ncua yuav tsum tau muab sib xyaw kom zoo. Hauv cov koob txhaj tshuaj, kos cua kom raws li qhov xav tau thiab nkag rau hauv lub vial yam tsis kov lub ncua kev kawm nws tus kheej. Tom qab ntawv, tsis tas yuav tawm ntawm rab koob, tig lub raj mis thiab sau cov koob xav tau ntawm Insuman.

Kev siv syringe cwjmem thiab cov cartridges, nws tseem yog qhov yuav tsum tau ntsuas lub xeev ntawm kev ncua nws tus kheej thiab kev ua yeeb yam ntawm cov koob txhaj tshuaj.Cov. Ua ntej kev tswj hwm, koj yuav tsum maj mam tig los yog co lub cuab yeej ob peb zaug kom thiaj li tau txais kev ncua ntawm homogeneous.

Yog daim duab syringe tawg, thiab tsis muaj lub sijhawm xaj los yuav ib qho tshiab tam sim no, koj tuaj yeem siv cov koob txhaj tshuaj. Insuman Bazal muaj 100 IU / ml, yog cov khoom siv tseem ceeb, yog li koj yuav tsum siv cov koob txhaj tshuaj tshwj xeeb tsim rau qhov ntau npaum li cas ntawm cov tshuaj.

Sab sij huam

Tawm tsam keeb kwm yav dhau los ntawm kev siv tas li ntawm Insuman, kev txhim kho ntawm:

  1. Hypoglycemia - nyob rau hauv cov ntaub ntawv ntawm lub koob tshuaj insulin ntau dua li ib txwm, lossis yog tias lub cev tsis xav tau ib qho;
  2. Hyperglycemia - muaj kev txhim kho ntau zaus, qhia qhov tsis txaus ntawm cov tshuaj insulin lossis txo qis hauv lub cev rhiab rau cov tshuaj.

Cov xwm txheej zoo li no nrog tus neeg mob kiv taub hau, ua rau tsis nco qab, tshee poob siab, hnov ​​qab txog kev tshaib plab. Tseem muaj kev mob taub hau heev, ntxhov siab, chim siab thiab cuam tshuam ntawm kev tsiv mus los.

Nrog kev poob qis hauv cov piam thaj hauv siab, cov neeg mob tsim muaj tachycardia, txo qis ntshav siab, thiab tawv nqaij daj.

Yog hais tias tsis muaj kev ntsuas tau coj mus, ib tus txwv zeej txwv koob teev nyob rau hauv, muaj qhov txawv ntawm lub siab, qhov kev hloov pauv ntawm lub siab, qhov txo qis hauv cov ntshav siab, qhov mob chua leeg mus txog qhov mob qaug dab peg yog qhov ua tau. Tom qab qhov kev tshwm sim zoo no, qhov kawg rov tshwm sim, uas ua rau muaj kev ploj tuag.

Kev txo qis thiab nce ntxiv nyob rau hauv cov piam thaj kuj tseem tuaj yeem ua qhov tsis xav ua rau tib neeg kev noj qab haus huv. Nyob rau hauv cov xwm txheej zoo li no, angiopathy ntawm cov nkoj me me ntawm ntau cov chaw loj hlob. Feem ntau, muaj qhov pom kev tsis zoo, tsaus nti hauv lub qhov muag. Tus mob no ntawm cov ntshav ncig ua rau txoj kev txhim kho kev dig muag.

Nrog cov kev qhia tas li ntawm cov kua dej hauv ib qhov chaw, atrophy ntawm cov nqaij mos subcutaneous tsim muaj, caws pliav tshwm sim. Tsis tas li, cov kev coj ua no tuaj yeem ua rau qhov tshwm sim ntawm voos lossis daim ntaub necrosis.

Cov tshuaj tiv thaiv tsis haum lub siab yuav tshwm sim ntawm cov khoom ntawm Insuman, uas yog nrog los ntawm khaus heev, tawm pob ntawm daim tawv nqaij, nrog rau mob tawv nqaij lossis ua rau xim dub, qhia tias cov nqaij mos necrosis (Arthus phenomenon). Tej zaum qhov tshwm sim ntawm kev ua pa nyuaj, qhia txog kev txhim kho ntawm bronchospasm, angioedema, liab ntawm txhua daim tawv nqaij.

Yog li, txhawm rau kom zam dhau qhov kev tshwm sim ntawm cov tshuaj tiv thaiv, thawj lub sijhawm ntawm kev noj Insuman tshwm sim hauv tsev kho mob, nyob rau hauv kev saib xyuas ntawm cov neeg tsim nyog.

Noj ntau dhau

Nrog cov lus qhia ntawm kev txhaj tshuaj ntau ntawm cov tshuaj insulin, ib qho kev tiv thaiv qog ntshav hauv lub cev ntau dua. Thaum thawj cov tsos mob tshwm sim, nws yog ib qho tsim nyog yuav tsum tau ua kev ntsuas kom nres qhov mob no. Ua ntej tshaj, koj yuav tsum tau ua qhov kev ntsuas maj tawm rau cov ntshav qab zib kom qis. Yog tias qhov ntsuas qis qis, koj yuav tsum nqa me me ntawm qab zib sab hauv.

Thaum poob ntawm kev nco qab, qhov kev sib kis ntawm cov piam thaj tau muab rau tus neeg raug tsim txom, mob qhov quav, thiab tom qab ntawd ib qho ncos txuas nrog cov kua nyeem ntawm qabzib. Tom qab uas tus neeg mob tau tso rau hauv kev soj ntsuam thiab cov ntshav qab zib cov ntshav tau ntsuas tas li.

Tseem Ceeb! Txawm tias tom qab siv ceev xwmphem tus mob no, kev tiv thaiv ntshav qab zib tsawg tuaj yeem tshwm sim uas yuav tsum tau saib xyuas mob. Tus neeg mob yuav tsum nyob twj ywm kev saib xyuas ntawm kws kho mob.

Kev cuam tshuam nrog lwm yam tshuaj

Kev siv tib lub sij hawm ntau yam ntawm cov tshuaj muaj suab thaj txo qis yuav ua rau kev txhim kho hypoglycemic coma, nws yog qhov tsim nyog los tswj kev ua kom tsawg ntawm cov tshuaj nrog koj tus kws kho mob.

Nws tseem raug txwv tsis pub noj Insuman nrog cov tshuaj uas tuaj yeem txo cov txiaj ntsig ntawm cov tshuaj tiv thaiv kab mob, lawv suav nrog: emtrogens, sympathomimetics, cov thyroid hormones, diuretics, somatotropin thiab nws cov tshuaj analogues, tshuaj tiv thaiv kev puas hlwb.

Yog tias tus neeg mob xav tau cov tshuaj no, lub sijhawm zoo li no yuav tsum pom zoo nrog tus kws kho mob mus kawm.

Analogs thiab kwv yees tus nqi

Tus nqi ntawm Insuman lub hauv paus ntawm thaj chaw ntawm Lavxias yog los ntawm 765.00 rubles rau 1,585 rubles.

Yog tias tsim nyog, peb tuaj yeem koom tes nrog kev siv yav tom ntej ntawm lwm yam Insuman Bazal analogues. Lawv yuav luag zoo ib yam hauv kev sib xyaw thiab sijhawm ua. Lawv kuj muaj ib qho kev sib txuas ntawm tib neeg cov tshuaj insulin, nrog rau qhov sib ntxiv ntawm lwm yam kev zam.

Cov keeb kwm ntawm Insuman Bazal yog:

  1. Protafan TM, ntau lawm - Denmark. Qhov hypoglycemic no tuaj yeem muas ntawm tus nqi ntawm 850 rubles rau 985 rubles.
  2. Rinsulin NPH, ntau lawm - Russia. Cov cuab yeej no muaj nyob rau hauv lub raj mis thiab daim cartridges, koj tuaj yeem yuav tus nqi ntawm 400 rubles rau 990 rubles.
  3. Humulin NPH, Ntau Lawm - USA. Hauv cov khw muag tshuaj tuaj yeem pom ntawm tus nqi ntawm 150-400 rubles.

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