Insulin Rapid yog nrov ntawm ob qho tib si neeg mob ntshav qab zib nrog thiab tsis muaj kev cuam tshuam insulin. Cov piam thaj hauv kev hnyav yog qhov tseem ceeb rau tib neeg lub cev, thaum nws cov khoom lag luam nres lossis lub cell receptors tsis pom zoo nws, cov piam thaj nyob hauv cov ntshav thiab ua rau muaj ntau qhov tsis zoo.
Nrog lub sijhawm tswj tsis tau ntawm cov ntsiab lus qab zib, hyperglycemia ntxias txoj kev pib tuag.
Yog li, tib neeg kev txom nyem los ntawm "tus kab mob qab zib" yuav tsum paub txog cov kab mob hypoglycemic yooj yim thiab cov tshuaj insulin txhawm rau txhawm rau ua kom cov ntshav qabzib nyob hauv cov kev txwv.
Tus txheej txheem ntawm kev ua ntawm cov tshuaj
Tau los ntawm kev tshuaj ntsuam genetic engineering, insulin Insuman Rapid GT zoo ib yam li cov tshuaj ua los ntawm tib neeg pancreatic beta hlwb. Cov tshuaj tau tawm hauv cov tshuaj uas tsis muaj xim, uas yog txhaj.
Cov tshuaj nquag siv ntawm cov tshuaj yog tib neeg cov tshuaj insulin. Ntxiv rau nws, qhov kev npaj muaj ib qho me me ntawm lwm qhov: glycerol (85%), sodium hydroxide, m-cresol, hydrochloric acid, sodium dihydrogen phosphate dihydrate thiab dej distilled.
Ib nrab ib teev tom qab cov tshuaj hormones nkag mus rau hauv tib neeg lub cev, nws pib ua. Qhov siab tshaj plaws ua rau kev kho mob tuaj dhau 1-3 teev tom qab txhaj tshuaj thiab kav ntev txog 8 teev. Thaum lub sijhawm nws ua, insulin muaj cov teebmeem hauv qab no ntawm lub cev:
- txo hauv cov piam thaj hauv ntshav;
- ntxiv dag zog rau cov txiaj ntsig anabolic, uas yog, hloov kho dua tshiab thiab tsim lub hlwb tshiab;
- kev txwv ntawm kev ua catabolic - kev zom zaubmov;
- ib qho kev nce hauv kev hloov pauv ntawm cov piam thaj mus rau hauv cov cell, kev tsim cov glycogen hauv lub siab thiab cov leeg;
- kev siv cov piam thaj ntawm cov khoom lag luam kawg - pyruvates;
- kev tsuj ntawm glycogenolysis, glyconeogenesis thiab lipolysis;
- nce lipogenesis hauv nqaij adipose thiab nplooj siab;
- txhim kho cov poov tshuaj kom tsawg dua hauv qib qis.
Hauv kev xyaum kho mob, Insuman Rapid yog sib xyaw nrog lwm tus tib neeg insulins, uas yog tsim los ntawm Hoechst Marion Roussel, tshwj tsis yog cov tshuaj hormones uas siv rau kev nqus dej infusions.
Cov lus qhia rau kev siv tshuaj
Cov sij hawm ntawm cov tshuaj insulin thiab cov tshuaj noj yog tsim los ntawm tus kws kho mob uas koom nrog, uas yuav tsum ua rau qhov ntsuas cov piam thaj thiab qhov hnyav ntawm tus neeg mob lub cev.
Tom qab yuav cov tshuaj, koj yuav tsum nyeem cov lus qhia nyob nrog. Yog tias koj muaj lus nug, koj yuav tsum sab laj nrog koj tus kws kho mob.
Thaum siv yeeb tshuaj, ib qho yuav tsum nruj me ntsis rau cov lus pom zoo tau txais los ntawm tus kws kho mob thiab cov lus pom zoo tau qhia hauv cov lus qhia rau kev siv.
Cov kev qhia muaj ib qho ua tiav cov xwm txheej uas siv cov tshuaj insulin:
- ib yam ntshav qab zib uas xav tau kev kho mob insulin;
- kev loj hlob ntawm tus mob ntshav qab zib tsis xeev (ketoacidotic lossis hypersmolar);
- ketoacidosis - qhov kev ua txhaum ntawm cov metabolism ntawm carbohydrates vim tsis muaj cov tshuaj insulin;
- ua tiav cov nyiaj them rau cov neeg mob ntshav qab zib uas yuav raug phais lossis thaum ua haujlwm.
Hauv cov lus qhia txuas nrog tsis muaj ntaub ntawv qhia txog kev noj tshuaj, nws tsuas yog kws kho mob sau tseg. Qhov siab tshaj plaws qhov koob tshuaj tsis dhau tshaj 0.5-1 IU / kg ib hnub. Tsis tas li ntawd, Txoj kev siv tshuaj sai sai yog siv nrog lub cev ntev ntawm cov tshuaj hormones, qhov tshuaj txhua hnub uas tsawg kawg yog 60% ntawm tag nrho cov tshuaj ntawm ob qho tshuaj. Yog hais tias tus neeg mob hloov ntawm lwm cov tshuaj mus rau Insuman Rapid, nws tus mob yuav tsum tau soj ntsuam los ntawm kws kho mob. Koj tuaj yeem qhia lub ntsiab lus tseem ceeb ntawm kev siv cov tshuaj no:
- cov kev daws tau muab 15-20 feeb ua ntej noj;
- kev txhaj tshuaj yog muab rau subcutaneously thiab intramuscularly;
- qhov chaw rau kev txhaj tshuaj yuav tsum tau hloov tas li;
- nrog hyperglycemic coma, ketoacidosis thiab metabolic them, cov tshuaj yog muab tshuaj kom khov;
- cov tshuaj tsis yog siv hauv cov tshuaj insulin;
- 100 IU / ml koob txhaj tshuaj siv rau kev txhaj tshuaj;
- Cov kua dej sai sai tsis sib xyaw nrog cov tshuaj hormones ntawm tsiaj thiab lwm yam keeb kwm, lwm yam tshuaj;
- Ua ntej txhaj tshuaj, kos cov tshuaj, yog tias muaj qee qhov hauv nws - cov lus qhia yog txwv tsis pub;
- ua ntej kev txhaj tshuaj, huab cua yog coj mus rau hauv cov koob txhaj (qhov ntim yog qhov sib npaug ntawm qhov ntim ntawm insulin), thiab tom qab ntawd tso tawm rau hauv lub vial;
- Qhov ntim ntawm qhov kev daws tau sau los ntawm vial thiab cov npuas muab tshem tawm;
- daim tawv nqaij yog tsau thiab cov tshuaj hormones yog maj mam qhia;
- tom qab tshem rab koob, tampon lossis paj rwb pas nrig tso rau ntawm qhov puncture;
- ntawm lub raj mis sau hnub uas txhaj thawj zaug.
Cov tshuaj no tau khaws cia rau hauv qhov chaw tsaus nti tsis muaj nkag mus rau cov menyuam yaus me. Cia cov khoom kub yog 2-8 degrees, cov tshuaj yuav tsum tsis txhob txhuam.
Lub txee lub neej yog 2 xyoos, tom qab lub sijhawm no nws yog txwv tsis pub siv tshuaj.
Cov txheej txheem ua kom tsis haum, ua kom muaj kev phom sij thiab siv tshaj
Cov tshuaj no tsuas muaj ob zaug contraindications - ib tug neeg rhiab rau lub Cheebtsam thiab cov menyuam yaus hnub nyoog txog ob xyoos.
Qhov kev txwv no vim yog qhov tseeb tias kev tshawb fawb tseem tsis tau ua tiav cov neeg muaj txuj ci sai sai rau cov menyuam yaus.
Cov yam ntxwv ntawm yeeb tshuaj yog qhov ua tau ntawm nws txoj kev siv thaum xeeb tub thiab pub niam mis.
Qee zaum, vim kev noj ntau dhau lossis lwm cov laj thawj, cov kev mob tshwm sim ntawm cov tshuaj tshwm sim:
- Cov ntshav qab zib tsawg, cov tsos mob ntawm kev uas tsaug zog, tachycardia, tsis meej pem, xeev siab, thiab ntuav.
- Lub sijhawm luv ua haujlwm ntawm qhov pom ntawm lub plab hnyuv siab raum, qee zaum kev txhim kho ntawm cov teeb meem - cov ntshav qab zib ua kom rov ua haujlwm. Tus kab mob no tshwm sim los ntawm o ntawm cov kab mob retina, uas ua rau daim duab plooj plooj nyob rau hauv pem hauv ntej ntawm lub qhov muag, ntau yam tsis xws luag.
- Lub ntsej muag rog lossis liab lossis tawv nqaij hauv thaj chaw txhaj tshuaj.
- Kev txhaum siab tsis haum yog qhov tsawg. Qhov no tuaj yeem yog angioedema, bronchospasm, txo qis ntshav siab lossis anaphylactic poob siab.
- Cov txheej txheem ntawm cov tshuaj tiv thaiv rau cov tshuaj tiv thaiv tshaj tawm.
- Khaws cov tshuaj sodium hauv tib neeg lub cev, vim qhov tshwm sim ntawm cov tshwm sim ntawm cov nqaij mos o.
- Txo cov poov tshuaj kom tsawg tsawg hauv lub cev, cov kab mob cerebral edema.
Yog tias tus neeg mob txhaj nws tus kheej nrog rau koob tshuaj insulin ntau dua li qhov xav tau, hauv txhua txoj kev yuav qhov no yuav ua rau muaj ntshav qab zib hauv ntshav qab zib mellitus. Thaum tus neeg mob nco qab, nws maj nrawm xav noj cov khoom muaj piam thaj ntau, thiab tom qab ntawd nws noj cov khoom noj carbohydrates.
Yog tias tus neeg tsis nco qab lawm, nws tau txhaj koob tshuaj glucagon (1 mg) rau cov tshuaj intramuscularly lossis cov kua dej qab zib (20 lossis 30 ml) txhaj tshuaj. Qhov xwm txheej yog qhov muaj peev xwm ua tau kom rov qab tswj xyuas cov piam thaj hauv qab. Qhov ntau npaum li cas ntawm glucagon los yog piam thaj rau ib tus menyuam yog xam raws nws qhov hnyav.
Kev cuam tshuam nrog lwm yam tshuaj
Thaum lub sij hawm hloov mus rau Insuman Rapid GT, tus kws kho mob ntsuas kev ua siab ntev ntawm cov tshuaj siv cov kev kuaj mob uas tsis muaj kev tiv thaiv kom tsis txhob muaj kev tiv thaiv kab mob. Thaum pib ntawm txoj kev kho, glycemic tawm tsam yog ua tau, tshwj xeeb tshaj yog nyob rau hauv cov neeg mob ntshav qab zib nrog cov ntshav qab zib cov ntsiab lus tsawg.
Kev siv tib lub sij hawm ntawm tib neeg cov tshuaj hormones, hypoglycemic thiab lwm yam kev cuam tshuam tuaj yeem cuam tshuam qhov kev nqis tes ntawm insulin Insuman Rapid hauv txoj kev sib txawv.
Cov npe tag nrho ntawm cov tshuaj tsis raug pom zoo tuaj yeem pom nyob hauv cov lus qhia tiav rau kev siv.
Kev siv cov tshuaj tiv thaiv beta-blockers nce ntau txoj kev pheej hmoo ntawm kev tsim lub xeev ntawm cov ntshav qab zib, ntxiv rau, lawv muaj peev xwm los npog nws cov tsos mob. Cov dej cawv haus cawv kuj tseem txo cov ntshav qab zib.
Cov ntshav qabzib tsawg zuj zus ua rau siv cov tshuaj no:
- salicylates, suav nrog acetylsalicylic acid;
- anabolic steroids, amphetamines, txiv neej pw ua ke;
- monoamine oxidase inhibitors (MAO);
- angiotensin hloov mus rau enzyme (ACE) inhibitors;
- qab zib cov tshuaj txo qis qis;
- tetracycline, sulfonamides, trophosphamides;
- cyclophosphamide thiab lwm tus.
Xws li cov tshuaj thiab cov yeeb yaj kiab tuaj yeem tsim kev puas tsuaj rau cov tshuaj insulin thiab nce cov piam thaj hauv cov ntshav:
- corticotropin;
- corticosteroids;
- barbiturates;
- danazole;
- glucagon;
- estrogens, progesterones;
- nicotinic acid thiab lwm tus.
Kev tawm tsam ntshav ntau ntawm cov ntshav qab zib muaj feem cuam tshuam rau kev mloog zoo, uas yog lub luag haujlwm tseem ceeb hauv kev tswj hwm tsheb lossis tsheb. Koj tuaj yeem nce ntxiv qabzib los ntawm kev noj noj qab zib lossis haus kua txiv uas qab zib.
Cov xwm txheej zoo li kev noj haus tsis txaus, hla kev txhaj tshuaj, kis kab mob thiab kis kab mob, thiab lub neej kev ua si kuj ua rau muaj suab thaj ntau ntau.
Nqi, tshuaj xyuas thiab analogues
Txhua tus, muaj kws kho mob sau ntawv yuav lawv, tuaj yeem yuav cov tshuaj hauv cov khw muag tshuaj lossis xaj nws online hauv Is Taws Nem. Tus nqi ntawm cov tshuaj insulin nyob ntawm ntau npaum li cas ntawm lub raj mis daws yog hauv pob. Yeej, tus nqi sib txawv ntawm 1000 txog 1460 Lavxias rubles rau pob ntawm cov tshuaj.
Kev ntsuam xyuas ntawm ntau tus neeg mob ntshav qab zib uas tau txhaj tshuaj insulin yog qhov zoo heev. Lawv tau ceeb toom txo qis hauv qab zib cov qib qis dua. Insulin Rapid GT tiag tiag muaj cov nyhuv sai, nws tus nqi kuj qis. Tib qhov tsis zoo ntawm cov tshuaj yog qhov tshwm sim ntawm nws cov kev mob tshwm sim ntawm qhov chaw txhaj tshuaj. Ntau tus tshaj tawm liab thiab khaus ntawm thaj chaw uas tau txhaj tshuaj. Qhov tshwm sim no tuaj yeem tshem tawm los ntawm kev txhaj tshuaj txhua zaus rau lwm qhov chaw lossis lwm qhov chaw.
Feem ntau, ob tus neeg mob thiab kws kho mob suav tias kev npaj tshuaj insulin no ua haujlwm zoo. Cov neeg mob tau txais txiaj ntsig zoo tshaj plaws los ntawm kev kho mob insulin thaum lawv ua raws li kev noj zaub mov uas tsis suav nrog cov khoom noj zom tau yooj yim thiab muaj suab thaj, kev tawm dag zog lub cev thiab tswj lawv lub cev qhov hnyav.
Thaum ib tug neeg tsis kam txais ua ke rau cov tshuaj, tus kws kho mob muaj lub luag haujlwm khaws ib qho insulin ntxiv rau tus neeg mob. Ntawm ntau cov tshuaj, txhais cov lus uas muaj tib cov tshuaj nquag tuaj yeem paub qhov txawv. Piv txwv li:
- Actrapid NM
- Biosulin P,
- Rinsulin P,
- Rosinsulin P,
- Humulin Tsis tu ncua.
Qee zaum tus kws kho mob xaiv cov kev kho zoo sib xws uas muaj lwm qhov tseem ceeb, tab sis muaj cov kev kho kom zoo li qub. Qhov no tuaj yeem yog Apidra, Novorapid Penfill, Novorapid Flexspen, Humalog thiab lwm yam tshuaj. Lawv tuaj yeem sib txawv hauv cov ntawv ntau npaum li cas, nrog rau nqi. Piv txwv, tus nqi nruab nrab ntawm cov tshuaj Humalog yog 1820 rubles, thiab pob nyiaj Apidra yog 1880 rubles. Yog li, kev xaiv cov tshuaj yog nyob ntawm ob qho tseem ceeb - qhov ua tau zoo ntawm kev kho mob rau tus neeg mob lub cev thiab nws cov peev nyiaj.
Ntawm ntau cov tshuaj insulin-zoo li, qhov ua tau zoo ntawm Insuman Rapid GT yog qhov ceeb toom. Cov tshuaj no txo cov piam thaj kom tsawg rau qib ib txwm.
Txij li cov tshuaj muaj qee qhov kev sib txuam thiab cov kev mob tshwm sim, nws txoj kev siv yog ua raws li kev saib xyuas nruj ntawm tus kws kho mob. Tab sis txhawm rau tshem tawm cov tsos mob ntshav qab zib thiab ua kom lub cev tsis zoo ntawm cov piam thaj, nws tsis yog tsim nyog txhawm rau kev txhaj tshuaj insulin, tab sis kuj tseem soj ntsuam kom muaj zaub mov noj kom zoo thiab ua lub neej muaj sia. Tsuas yog txoj hauv kev no tuaj yeem ua tus neeg kom ntseeg tau lub neej zoo thiab tag nrho. Daim vis dis aus hauv tsab xov xwm no yuav tham txog qee hom tshuaj insulin.
