Vipidia yog ib qho tshuaj uas tsim los kho ntshav qab zib ntawm yam tsis muaj tshuaj insulin.
Cov tshuaj siv ob qho tib si hauv kev siv tshuaj monotherapy, thiab hauv txoj kev kho mob hnyav ua tus kab mob ua ib feem ntawm kev kho tshuaj.
Alogliptin yog ib hom tshuaj tshiab uas siv hauv kev kho mob ntshav qab zib, uas tsis yog kev cuam tshuam rau cov tshuaj insulin. Cov tshuaj ntawm hom no zwm rau ib pawg tshuaj uas hu ua incretinomimetics.
Cov pab pawg no suav nrog glucagon-zoo li thiab piam thaj-insulinotropic polypeptides glucose-nyob. Cov tebchaw no teb rau tib neeg kev noj haus los ntawm kev ua kom lub zog ntawm cov tshuaj insulin.
Nyob hauv pawg muaj 2 pawg me ntawm incretin mimetics:
- Lub tebchaw muaj qhov kev ua uas zoo ib yam li qhov kev ua ntawm incretins. Xws li cov tshuaj lom neeg muaj xws li liraglutide, exenatide thiab lixisenatide.
- Lub tebchaw uas muaj peev xwm ua kom ntev ntawm qhov kev txiav txim ntawm incretins synthesized hauv lub cev. Kev ncua ntawm kev ua kom nce ntxiv tshwm sim vim kev txo qis ntawm kev tsim tawm ntawm cov enzyme tshwj xeeb, dipeptidyl peptidase-4, uas coj cov kev puas tsuaj ntawm incretins. Cov kev sib txuas no suav nrog sitagliptin, vildagliptin, saxagliptin, linagliptin thiab alogliptin.
Alogliptin muaj qhov ua rau xaiv qhov ua tau zoo ntawm cov xim tshwj xeeb dipeptidyl peptidase-4. Xaiv cov nyhuv inhibitory rau cov enzyme DPP-4 hauv alogliptin yog ntau dua piv rau cov txiaj ntsig zoo ib yam li ntawm cov enzymes ntsig txog.
Vipidia tuaj yeem khaws cia rau peb xyoos. Tom qab lub sijhawm no, kev siv tshuaj yog txwv tsis pub. Cov chaw khaws cia ntawm cov tshuaj yuav tsum tiv thaiv kom tsis txhob raug tshav ntuj. Thiab qhov kub nyob hauv qhov chaw khaws cia yuav tsum tsis pub tshaj 25 degrees.
Kev taw qhia thiab contraindications rau siv
Vipidia yog qhov tshuaj kho qhov ncauj hypoglycemic. Cov cuab yeej no siv rau hauv kev kho mob ntawm ntshav qab zib hom 2. Cov tshuaj diabetic no pab txhim kho kev tswj glycemia hauv ntshav ntshav ntawm tus neeg mob. Ib qho tshuaj yog siv thaum siv los kho kev noj haus thiab ua kom lub cev qoj ib ce tsis ua rau xav kom ua.
Cov tshuaj tuaj yeem siv ua ib qho kev tivthaiv thaum lub sijhawm kho monotherapy. Ib qho ntxiv, Vipidia tuaj yeem siv ua ke nrog lwm cov tshuaj hypoglycemic hauv kev kho mob hom 2 ntshav qab zib mellitus los ntawm tus qauv ntawm cov kev kho mob kho.
Cov tshuaj tuaj yeem siv hauv kev kho mob ntshav qab zib nyob rau hauv kev sib xyaw nrog insulin.
Zoo li txhua yam tshuaj, Vipidia muaj ib tug xov tooj ntawm contraindications uas txwv tsis pub siv cov tshuaj no. Lub ntsiab contraindications muaj raws li nram no:
- muaj cov ntshav qab zib hom 2 hauv tus neeg mob, txo lub cev rau alogliptin thiab ntu sib xyaw ntawm cov tshuaj;
- tus neeg mob muaj ntshav qab zib ua ib hom tshuaj insulin;
- cov cim qhia ntawm ketoacidosis txhim kho hauv tus neeg mob lub cev tiv thaiv keeb kwm ntawm ntshav qab zib;
- kev txheeb xyuas ntawm lub plawv tsis ua haujlwm hnyav;
- kev puas tsuaj nyob hauv daim siab, uas nrog nrog qhov tshwm sim ntawm kev ua tsis taus haujlwm;
- kev txhim kho ntawm cov kab mob hnyav ntawm lub raum, uas nrog los ntawm qhov tshwm sim ntawm kev ua haujlwm tsis txaus ntseeg;
- lub sij hawm ntawm kev xeeb tub;
- lactation lub sijhawm;
- tus neeg mob lub hnub nyoog txog 18 xyoo.
Ceev faj yuav tsum tau ua thaum tus neeg mob muaj mob pancreatitis thiab mob hnyav rau lub raum thiab lub siab ua haujlwm tsis zoo.
Tsis tas li ntawd, ceev faj yuav tsum tau siv thaum siv cov tshuaj los ua ib qho kev kho mob hauv kev kho mob ntshav qab zib hom II.
Cov lus qhia rau kev siv tshuaj
Cov tshuaj tau noj ntawm qhov ncauj. Feem ntau, cov tshuaj kho tau pom zoo rau kev siv yog 25 mg.
Kev siv tshuaj ntau dua qhov tseeb ntawm kev siv tshuaj yog tshuaj los ntawm tus kws kho mob koom nrog saib xyuas cov txiaj ntsig tau thaum lub sijhawm kuaj ntawm tus neeg mob lub cev thiab nws tus yam ntxwv.
Cov tshuaj no yuav noj ib hnub ib zaug, cov tshuaj noj yog hais txog lub caij noj mov. Kev noj cov tshuaj yog nrog haus dej kom ntau.
Kev siv tshuaj yog ua tau nyob rau hauv cov teeb meem hauv qab no:
- Raws li cov tshuaj rau monotherapy ntawm hom 2 mob ntshav qab zib mellitus.
- Hauv kev siv cov kev kho mob cuam tshuam ntawm tus kab mob, raws li kev tivthaiv ntawm kev kho mob. Concomitantly nrog vipidia, metformin, sulfonylurea derivatives los yog insulin tuaj yeem noj.
Hauv Vipidia hauv kev sib xyaw nrog Metformin, kev kho me ntsis rau kev txhaj tshuaj tsis tas yuav tsum muaj. Kev txhaj tshuaj yog xav tau thaum siv cov tshuaj txuam nrog cov tshuaj uas yog sulfonylurea derivatives lossis insulin.
Cov koob tshuaj tau hloov kho kom tiv thaiv qhov pib ntawm hypoglycemic lub xeev nyob rau hauv tus neeg mob ntshav qab zib mellitus.
Kev ceev faj yuav tsum muaj zog thaum siv Vipidia txuam nrog Metformin Teva thiab thiazolidinedione kev kho mob ntshav qab zib.
Thaum thawj cov tsos mob tshwm sim ntawm kev mob ntshav qab zib tshwm sim, qhov ntau npaum ntawm Metformin thiab thiazolidinedione yuav tsum raug txo kom tsawg.
Thaum noj Vipidia, cov kev mob tshwm sim tom qab no tuaj yeem tshwm sim:
- los ntawm cov leeg hlwb, tshwm sim ntawm cov mob taub hau heev;
- los ntawm lub plab zom mov, qhov tshwm sim ntawm kev mob hauv plab, ntuav cov ntsiab lus ntawm lub plab mus rau txoj hlab pas, kev txhim kho cov cim ntawm kev mob nraub qaum;
- los ntawm cov kab mob hepatobiliary, qhov tshwm sim ntawm kev tsis sib haum xeeb hauv kev ua haujlwm ntawm daim siab ua haujlwm tau;
- kev ua xua tuaj yeem tshwm sim nyob rau hauv daim ntawv ntawm khaus, tawm pob, Quincke's edema;
- o ntawm cov ntswg mucosa thiab pharynx yog ua tau;
Tsis tas li ntawd, lub cev tiv thaiv kab mob tuaj yeem ua rau mob tshwm sim, tshwm sim hauv daim ntawv ntawm anaphylaxis.
Tus nqi ntawm Vipidia thiab nws cov analogues
Kev siv cov Vipidia ntsiav tshuaj rau cov ntshav qab zib feem ntau yog qhov zoo.
Yog tias peb txiav txim siab kev noj tshuaj los ntawm kev tshuaj xyuas uas cov neeg uas siv Vipidia tawm txog nws, peb tuaj yeem xaus tias cov tshuaj yog cov tshuaj zoo heev uas tuaj yeem tswj tau theem ntawm glycemia hauv lub cev ntawm tus neeg mob ntshav qab zib hom 2.
Cov tshuaj noj rau cov tshuaj uas nquag, uas yog alogliptin rau hnub tim, ntxiv rau Vipidia tsis tau sau npe.
Cov tshuaj tsim, cov nquag ua haujlwm ntawm cov uas sib txuas nrog rau pawg pab pawg nce.
Cov tshuaj ib txwm siv uas yog cov tshuaj analogues ntawm Vipidia yog cov hauv qab no:
- Januvia yog cov tshuaj hypoglycemic tsim los ntawm sitagliptin. Qhov tso tawm ntawm cov tshuaj yog nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj uas muaj 25, 50 thiab 100 mg ntawm qhov cuam tshuam. Cov lus qhia rau kev siv Januvia yog zoo ib yam li cov uas Vipidia muaj. Cov tshuaj no tuaj yeem siv nrog monotherapy lossis nrog txoj kev kho mob nyuaj.
- Yanumet yog kev npaj ua, uas muaj cov sitagliptin thiab metformin ua cov khoom siv nquag. Cov koob tshuaj ntawm thawj cov tshuaj tiv thaiv yog 50 mg, thiab metformin hauv cov tshuaj muaj pes tsawg leeg yuav muaj nyob hauv ntau qhov nyiaj. Cov tshuaj muaj nyob rau hauv peb ntau yam - 50, 850 thiab 1000 mg.
- Galvus ua cov haujlwm tseem ceeb muaj cov vildagliptin, uas yog ib qho tshuaj sib piv ntawm alogliptin. Qhov ntau npaum li cas ntawm cov khoom sib txuam hauv qhov kev npaj yog 50 mg. Kev noj cov tshuaj metformin hauv tshuaj muaj pes tsawg leej yog 500, 850, thiab 1000 mg.
- Onglisa nyob rau hauv nws cov muaj pes tsawg leeg ua ib qho kev nquag ua ke muaj saxagliptin. Cov compound no cuam tshuam rau cov tebchaw uas yog cov inhibitors ntawm cov enzyme depleting incretin. Cov tshuaj muaj nyob hauv ib qhov ntau npaum ntawm 2.5 thiab 5 mg.
- Combogliz Prolong yog kev sib xyaw ntawm saxagliptin nrog metformin. Cov tshuaj no muaj nyob hauv daim foos. Tshaj tawm ntawm cov nquag muaj tshwm sim hauv daim ntawv qeeb.
- Trazhenta yog qhov tshuaj hypoglycemic ua rau lub hauv paus ntawm linagliptin. Cov tshuaj sib xyaw cov tshuaj muaj 5 mg ntawm cov tshuaj tiv thaiv nquag.
Tus nqi ntawm ib cov tshuaj nyob ntawm thaj av uas cov tshuaj muag hauv Lavxias. Tus nqi nruab nrab ntawm cov tshuaj no yog 843 rubles.
Dab tsi lwm yam kev kho mob tuaj yeem siv hauv kev kho mob ntshav qab zib tau piav qhia hauv video hauv tsab xov xwm no.
