Apidra yog txoj kev them se ntawm tib neeg cov tshuaj insulin, cov khoom siv tseem ceeb yog glulisin. Qhov peculiarity ntawm cov tshuaj yog tias nws pib ua haujlwm nrawm dua li tib neeg cov tshuaj insulin, tab sis lub sijhawm ua haujlwm ntawm lub sijhawm qis dua.
Daim ntawv muab cov kua dej ntawm cov tshuaj insulin no yog kev daws teeb meem rau kev tswj hwm ntawm cov dej, cov kua ntshiab ntshiab lossis tsis muaj ntshav. Ib ml ntawm cov tshuaj muaj 3.49 mg ntawm cov tshuaj nquag, uas yog sib npaug 100 IU ntawm tib neeg cov tshuaj insulin, nrog rau cov neeg tsis suav, suav nrog dej rau txhaj tshuaj thiab sodium hydroxide.
Tus nqi ntawm insulin Apidra sib txawv raws li tus nqi sib pauv tam sim no. Qhov nruab nrab hauv teb chaws Russia, tus kab mob ntshav qab zib tuaj yeem yuav ib cov tshuaj rau 2000-3000 txhiab rubles.
Kho kev nyhuv ntawm cov tshuaj
Qhov kev txiav txim siab tseem ceeb tshaj plaws ntawm Apidra yog qhov kev tsim nyog ntawm kev ua haujlwm ntawm cov ntshav qabzib hauv cov ntshav, insulin tuaj yeem txo qis cov piam thaj, thiaj li txhawb nws txoj kev nqus los ntawm cov ntaub so ntswg:
- rog;
- pob txha leeg.
Cov tshuaj insulin txwv kev tsim cov piam thaj hauv tus neeg mob lub siab, adipocyte lipolysis, proteolysis, thiab nce protein ntxiv.
Hauv cov kev tshawb fawb qhia txog cov neeg muaj kev noj qab haus huv thiab cov neeg mob ntshav qab zib mellitus, nws tau pom tias subcutaneous tswj hwm ntawm glulisin muab cov nyhuv sai dua, tab sis nrog lub sijhawm luv dua, thaum piv nrog soluble tib neeg cov kua dej.
Nrog kev siv tshuaj subcutaneous ntawm cov tshuaj, cov nyhuv hypoglycemic yuav tshwm sim tsis pub dhau 10-20 feeb, nrog kev txhaj tshuaj rau cov nyhuv no yog sib npaug hauv lub zog rau kev nqis tes ua ntawm tib neeg insulin. Chav Apidra yog tus cwj pwm los ntawm kev ua haujlwm hypoglycemic, uas sib npaug rau chav ntsuas ntawm tib neeg cov kua dej.
Apidra insulin muab rau 2 feeb ua ntej noj mov, uas tso cai rau kev tswj tus mob glycemic tom qab noj mov, zoo ib yam li tib neeg cov insulin, uas tau siv 30 feeb ua ntej noj mov. Nws yuav tsum tau sau tseg tias xws li kev tswj hwm yog qhov zoo tshaj plaws.
Yog hais tias glulisin noj 15 feeb tom qab noj mov, nws muaj peev xwm tswj tau los ntawm cov ntshav qab zib concentration, uas sib npaug rau tib neeg cov insulin muab 2 feeb ua ntej noj mov.
Cov tshuaj insulin yuav nyob hauv cov ntshav li 98 feeb.
Cov lus qhia rau kev siv tshuaj
Kev qhia txog kev siv tshuaj insulin Apidra SoloStar yog insulin-tiv thaiv ntshav qab zib mellitus ntawm hom thawj thiab hom thib ob, cov tshuaj no tuaj yeem kho rau cov laus thiab menyuam yaus hnub nyoog 6 xyoo. Cov tshuaj tiv thaiv yuav yog hypoglycemia thiab ib tug neeg tsis kam txais rau ib feem twg ntawm cov tshuaj.
Thaum cev xeeb tub thiab pub niam mis, Apidra yog siv nrog kev ceev faj heev.
Kev siv tshuaj insulin tam sim ntawd ua ntej noj mov lossis 15 feeb ua ntej. Nws tseem raug tso cai siv cov tshuaj insulin tom qab noj mov. Feem ntau, Apidra SoloStar pom zoo kom siv cov tshuaj insulin rau ib nrab-ntev ntev, nrog rau kev ua haujlwm ntev ntev ntawm insulin. Rau qee cov neeg mob, nws yuav raug suav nrog cov ntsiav tshuaj hypoglycemic.
Rau txhua tus mob ntshav qab zib, ib qho kev noj tshuaj rau ib tus neeg yuav tsum tau xaiv, noj rau hauv tus account tias nrog lub raum tsis ua haujlwm, qhov kev xav tau rau cov tshuaj hormones no yog txo qis.
Cov tshuaj muaj peev xwm tso cai rau noj tshuaj subcutaneously, infusion mus rau thaj chaw ntawm cov rog subcutaneous. Cov chaw yooj yim tshaj plaws rau kev siv tshuaj insulin:
- Plab
- ncej puab
- xwb pwg.
Thaum muaj qhov xav tau txuas ntxiv Txoj kev lis ntshav, qhov kev qhia yog nqa tawm hauv plab xwb. Cov kws kho mob xav pom zoo hloov chaw txhaj tshuaj, nco ntsoov ntsuas kev ntsuas kev nyab xeeb. Qhov no yuav tiv thaiv kev nkag ntawm insulin mus rau hauv cov hlab ntshav. Kev tswj hwm hauv qab ntu ntawm phab ntsa hauv thaj chaw ntawm lub plab yog qhov kev lees paub ntawm kev nqus ntau tshaj plaws ntawm cov tshuaj dua li nws cov lus qhia mus rau lwm qhov chaw ntawm lub cev.
Tom qab txhaj tshuaj, nws yog txwv tsis pub zaws qhov chaw txhaj tshuaj, tus kws kho mob yuav tsum qhia txog qhov no thaum lub sijhawm piav qhia txog cov txheej txheem kom raug rau kev tswj hwm cov tshuaj.
Nws yog ib qho tseem ceeb kom paub tias cov tshuaj no yuav tsum tsis txhob xyaw nrog lwm cov tshuaj insulins, tsuas yog kev zam rau txoj cai no nkaus xwb yog cov tshuaj insulin Isofan. Yog tias koj sib xyaw Apidra nrog Isofan, koj yuav tsum hu nws ua ntej thiab tam sim ntawd prick.
Daim cartridges yuav tsum siv nrog OptiPen Pro1 koob txhaj tshuaj lossis nrog cov khoom siv zoo sib xws, nco ntsoov ua raws li cov kws tsim cov lus pom zoo:
- lub thawv sau;
- koom tes ua rab koob;
- kev qhia ntawm cov tshuaj.
Txhua lub sijhawm ua ntej siv cov cuab yeej, nws yog ib qho tseem ceeb kom ua qhov kev soj ntsuam ntawm nws; kev daws teeb meem txhaj tshuaj yuav tsum tsis muaj pob tshab, tsis muaj xim ntau, tsis muaj cov khoom pom.
Ua ntej kev teeb tsa, lub cartridge yuav tsum ceev cia nyob rau hauv chav tsev qhov tsawg kawg yog 1-2 teev, tam sim ntawd ua ntej kev qhia ntawm insulin, huab cua yog tshem tawm ntawm daim cartridge. Kev siv daim laub rov qab yuav tsum tsis txhob rov ntim tshuaj dua; Thaum siv lub tshuab nqus dej twj tso kua mis los tsim cov tshuaj insulin tas mus li, sib xyaw nws yog qhov txwv!
Xav paub ntau ntxiv, thov nyeem cov lus qhia rau kev siv. Cov neeg mob hauv qab no yog kev kho tshwj xeeb:
- nrog lub raum khiav tsis zoo (yuav tsum tau los saib xyuas qhov koob tshuaj ntawm insulin);
- nrog lub siab ua haujlwm tsis zoo (qhov xav tau rau ib yam tshuaj hormones tuaj yeem txo qis).
Tsis muaj cov ntaub ntawv hais txog kev tshawb fawb pharmacokinetic tshuaj ntawm cov neeg laus hauv cov neeg laus, txawm li cas los xij, nws yuav tsum tau yug los rau hauv lub siab tias pawg neeg ntawm cov neeg mob no yuav txo qis qhov xav tau ntawm insulin vim yog lub raum tsis ua haujlwm.
Apidra insulin vials tuaj yeem siv nrog lub twj tso kua mis ua haujlwm ntawm cov kua dej, ib qho ntsuas dej ntawm insulin nrog cov nplai tsim nyog. Tom qab txhua qhov kev txhaj tshuaj, rab koob raug tshem tawm ntawm koob txhaj tshuaj thiab muab pov tseg. Txoj hau kev no yuav pab tiv thaiv kev kis mob, khoo tshuaj, cua nkag mus, thiab txhaws ntawm rab koob. Koj sim tsis tau nrog koj kev noj qab haus huv thiab rov siv rab koob.
Txhawm rau tiv thaiv kev kis mob, tus cwj mem ntim puv siv tsuas yog siv los ntawm ib qho mob ntshav qab zib, nws tsis tuaj yeem hloov mus rau lwm tus neeg.
Cov kab mob ntawm kev haus dej cawv ntau dhau thiab muaj kev cuam tshuam tsis zoo
Feem ntau, tus neeg mob ntshav qab zib muaj peev xwm tsim muaj qhov tsis zoo yam li ua rau lub cev tsis muaj ntshav qab zib.
Hauv qee kis, cov tshuaj ua rau cov tawv nqaij ua paug thiab o ntawm qhov chaw txhaj tshuaj.
Qee lub sij hawm nws yog cov lus nug ntawm lipodystrophy hauv ntshav qab zib mellitus, yog tias tus neeg mob tsis ua raws li kev pom zoo ntawm kev hloov chaw ntawm kev txhaj tshuaj insulin.
Lwm cov kev tsis haum tshuaj suav nrog:
- ua tsis taus pa, urticaria, ua xua dermatitis (feem ntau);
- hauv siab nruj (tsis tshua muaj).
Nrog cov kev tshwm sim ntawm cov kev tawm tsam tsis haum, muaj kev phom sij rau tus neeg mob lub neej. Vim li no, nws tseem ceeb uas yuav tau ua tib zoo saib xyuas koj kev noj qab haus huv thiab mloog nws cov kev ntxhov siab me ntsis.
Thaum kev siv ntau tshaj ntawd tshwm sim, tus neeg mob nthuav dav hypoglycemia ntawm kev ua txhaum sib txawv. Hauv qhov no, kev kho mob yog qhia:
- mob ntshav qab zib tsawg - siv cov zaub mov uas muaj suab thaj (hauv cov ntshav qab zib lawv yuav tsum nrog lawv nyob);
- Kev mob ntshav qab zib ntau nrog rau qhov tsis nco qab - nres tau ua los ntawm kev tswj hwm 1 ml ntawm glucagon subcutaneously lossis intramuscularly, qabzib tuaj yeem muab tshuaj rau hauv ntshav (yog tias tus neeg mob tsis teb rau glucagon).
Sai li tus neeg mob rov qab nco ntsoov, nws yuav tsum tau noj me me ntawm carbohydrates.
Raws li qhov tshwm sim ntawm hypoglycemia lossis hyperglycemia, muaj kev pheej hmoo ntawm tus neeg mob lub cev tsis muaj peev xwm ua kom pom tseeb, hloov qhov ceev ntawm cov kev puas hlwb psychomotor. Qhov no ua rau muaj kev hem thawj thaum tsav tsheb lossis lwm yam txheej txheem.
Kev saib xyuas tshwj xeeb yuav tsum tau muab rau cov neeg mob ntshav qab zib uas muaj qhov txo qis lossis tsis tuaj yeem muaj peev xwm paub txog cov cim ntawm qhov yuav tsum ua kom muaj ntshav qab zib tsawg. Nws tseem yog qhov tseem ceeb rau kev mob ncua ntev ntawm skyrocketing qab zib.
Cov neeg mob zoo li no yuav tsum txiav txim siab txog qhov ua tau ntawm kev tswj hwm cov tsheb thiab cov txheej txheem ntawm tus kheej.
Lwm yam lus pom zoo
Nrog rau cov tib neeg siv cov tshuaj insulin Apidra SoloStar nrog qee yam tshuaj, ib qho nce lossis qis dua hauv kev txhawb nqa rau kev txhim kho hypoglycemia tuaj yeem pom, nws yog kev coj los cuam tshuam nrog cov tshuaj no:
- qhov ncauj hypoglycemic;
- ACE inhibitors;
- fibrates;
- Disopyramids;
- MAO inhibitors;
- Fluoxetine;
- Pentoxifylline;
- salicylates;
- Propoxyphene;
- sulfonamide antimicrobials.
Qhov ua rau lub ntsej muag ntshav siab tuaj yeem txo qis ntau zaus yog tias cov tshuaj insulin glulisin muab ua ke nrog cov tshuaj: diuretics, phenothiazine derivatives, thyroid hormones, protease inhibitors, antipsychotropic, glucocorticosteroids, Isoniazid, Phenothiazine, Somatropin, sympathomimetics.
Cov tshuaj Pentamidine yuav luag ib txwm muaj hypoglycemia thiab hyperglycemia. Ethanol, kua ntsev lithium, beta-blockers, cov tshuaj Clonidine tuaj yeem muaj peev xwm thiab muaj zog me ntsis cov nyhuv hypoglycemic.
Yog tias nws yuav tsum hloov ntshav qab zib mus rau lwm hom tshuaj insulin lossis lwm hom tshuaj tshiab, kev saib xyuas nruj los ntawm tus kws kho mob koom yog qhov tseem ceeb. Thaum kev siv tshuaj tsis txaus ntawm cov tshuaj insulin siv los yog tus neeg mob txiav txim siab txiav txim siab txog kev kho, qhov no yuav ua rau kev txhim kho:
- hyperglycemia hnyav;
- mob ketoacidosis.
Ob qho xwm txheej no ua rau muaj kev hem thawj rau lub neej ntawm tus neeg mob.
Yog tias muaj kev hloov pauv ntawm cov yam ntxwv lub cev, qhov ntau thiab cov zaub mov noj, kev hloov kho ntawm Apidra insulin kuj yuav tsum tau ua. Cov kev tawm dag zog lub cev uas tshwm sim tam sim ntawd tom qab noj mov tuaj yeem ua rau muaj qhov txo qis ntawm cov ntshav qab zib tsawg.
Tus neeg mob ntshav qab zib hloov pauv qhov xav tau ntawm insulin yog tias nws muaj kev xav ntau dhau lossis mob tsis sib haum. Cov qauv no yog lees paub los ntawm kev txheeb xyuas, ob tus kws kho mob thiab cov neeg mob.
Apidra insulin yog qhov tsim nyog yuav tsum tau muab cia rau hauv qhov chaw tsaus, uas yuav tsum muaj kev tiv thaiv los ntawm menyuam yaus rau 2 xyoos. Qhov zoo tshaj plaws kub rau khaws cov tshuaj yog los ntawm 2 txog 8 degrees, nws yog txwv tsis pub kom khov cov tshuaj insulin!
Tom qab pib siv, cov laub yuav khaws cia ntawm qhov ntsuas kub tsis tshaj 25 degrees, lawv tsim nyog siv rau ib hlis.
Apidra insulin cov lus qhia yog muab tso rau hauv cov yeeb yaj kiab hauv tsab xov xwm no.