Trypsin yog ib qho proteolytic enzyme (enzyme) uas yog zais cia los ntawm exocrine ib feem ntawm lub txiav. Thaum pib, nws tus thawj ntawm hauv ib lub xeev tsis muaj zog, trypsinogen, yog tsim tawm.
Nws nkag mus rau ntawm duodenum 12, thiab nyob ntawd nws tau qhib vim kev ua ntawm lwm lub enzyme rau nws - enterokinase.
Cov qauv ua kom muaj tshuaj lom neeg ntawm trypsin tau faib ua cov protein. Hauv kev coj ua, nws tau txais los ntawm nyuj.
Cov haujlwm tseem ceeb tshaj plaws ntawm trypsin yog proteolysis, i.e. kev faib cov protein thiab polypeptides rau hauv cov khoom me - cov amino acids. Nws yog catalytic enzyme.
Hauv lwm lo lus, trypsin zom cov protein ntau. Lwm qhov kev txiav txim siab rau pancreatic tseem paub - lipase, uas koom nrog kev zom cov rog, thiab alpha-amylase, uas zom cov carbohydrates. Amylase tsis yog tsuas yog pancreatic enzyme, nws kuj tseem ua ke nyob rau hauv cov qog ua kua qaub, tab sis hauv cov khoom me me.
Trypsin, amylase thiab lipase yog qhov tseem ceeb tshaj nyob hauv cov hnyuv. Thaum tsis muaj tsawg kawg ntawm ib ntawm lawv, kev zom zaub mov yog qhov tsis muaj zog.
Ntxiv nrog rau kev koom nrog kev zom, lub trypsin enzyme ua tau zoo rau kev kho ntau yam kab mob:
- pab txo kev mob hauv lub cev;
- kev kho sai sai ntawm kub nyhiab, mob hnyav;
- muaj peev xwm cais cov ntaub so ntswg tuag kom cov khoom ntawm necrosis tsis nkag rau cov hlab ntshav thiab ua rau intoxication;
- ua rau nyias zais zis, tso zis ua kua ntau dua;
- facilitates liquefaction ntawm cov ntshav txhaws;
- pab txhawm rau kho cov kab mob nrog fibrinous o;
- txhim kho kev tshem tawm ntawm huab hwm coj purulent;
- kho qhov mob txhab loj ntawm lub qhov ncauj tawm;
Hauv lub xeev tsis muaj zog, qhov chaw sib xyaw ua ke no nyab xeeb kiag li.
Txij li thaum trypsin muaj cov lus hais txog kev kho kom zoo, nws yog siv rau kev tsim cov tshuaj.
Zoo li lwm yam tshuaj muaj yees ntawm ib qho yeeb tshuaj twg, kev siv cov trypsin nws muaj nws qhov taw qhia thiab contraindications rau siv.
Thaum siv cov tshuaj uas suav nrog trypsin, kws kho mob cov lus pom zoo thiab cov lus qhia txog kev siv tshuaj yuav tsum ua raws cai.
Kev faib tawm Trypsin:
- Amorphous - nws tuaj yeem siv tsuas yog siv tshuaj pleev (nyob rau thaj tsam ntawm daim tawv nqaij tsawg.
- Crystalline - los hauv daim ntawv ntawm cov hmoov dawb-daj, nrog qhov tsis muaj tus yam ntxwv tsis hnov tsw. Nws yog siv ob qho tib si saum toj kawg nkaus thiab rau kev tswj hwm intramuscular.
Trypsin muaj nyob rau hauv cov npe sib txawv: "Pax-trypsin", "Terridekaza", "Ribonuclease", "Asperase", "Lizoamidase", "Dalcex", "Profezim", "Irukson". Txhua yam kev npaj ua yuav tsum tau muab cia rau qhov chaw qhuav thiab tsaus ntawm qhov kub tsis tshaj kaum theem.
Kev qhia rau kev siv yog:
- mob kab mob ntawm lub ntsws thiab txoj hlab pa (mob ntsws, mob ntsws, exudative pleurisy);
- tus mob bronchiectatic (qhov tshwm sim ntawm cov mob txuas ntxiv hauv bronchi);
- mob kub hnyiab thiab qhov mob nrog purulent tawm;
- mob o ntawm pob ntseg hauv nruab nrab (otitis media);
- purulent o ntawm qhov ua rau hle ntawm sab xub ntiag thiab maxillary cov hlab ntsha;
- mob hlwb pob txha (osteomyelitis);
- ncig cov kab mob;
- thaiv ntawm lub lacrimal kwj dej;
- o ntawm tus iris;
- ua paug siab;
- teeb meem tom qab kev phais qhov muag.
Cov kev tsis sib haum rau kev siv ntawm trypsin yog:
- Kev ua xua rau trypsin.
- Ntxiv kev ua kom zoo nkauj ntawm lub ntsws, lossis emphysema.
- Tsis txaus ntseeg ntawm lub plawv muaj nuj nqi.
- Dystrophic thiab mob pauv hauv lub siab.
- Tub Ntshaw
- Mob raum.
- Pancreatitis yog muaj mob.
- Kev ua txhaum nyob rau hauv coagulation thiab anticoagulation system.
- Cov kev ua rau lub raum (jade).
- Hemorrhagic diathesis.
Dab tsi tuaj yeem yog cov kev mob tshwm sim tom qab siv trypsin?
- ua xua
- plawv dhia;
- liab thiab mob tom qab txhaj tshuaj intramuscular;
- hyperthermia.
Ib qho ntxiv, txhaws qaj yuav tshwm hauv tus neeg mob lub suab.
Thaum ua ntawv thov saum toj rau kev kho cov qhov txhab lossis qhov txhab nrog cov ntaub so ntswg tuag, trypsin impregnated compresses yog siv.
Txhawm rau ua qhov no, koj yuav tsum yaj kom yaj 50 mg ntawm qhov kev npaj enzyme hauv 50 mg ntawm physiological saline (sodium chloride, lossis 0.9% saline).
Feem ntau siv cov txheej txheem tshwj xeeb tsim peb-txheej ntaub so.
Tom qab thov lub zaws, nws yog tsau nrog cov ntaub qhwv thiab sab laug rau nees nkaum plaub teev.
Kev tswj hwm intramuscular 5 mg ntawm trypsin yog diluted hauv 1-2 ml ntawm saline, lidocaine lossis novocaine. Hauv cov laus, kev txhaj tshuaj yog tsim ob zaug ib hnub, rau menyuam yaus - ib zaug nkaus xwb.
Kev siv intrapleural. Tom qab kev qhia ntawm cov tshuaj, koj tsis tuaj yeem nyob hauv tib txoj hauj lwm ntev, vim qhov no ua rau nws nyuaj rau tsis pub lwm tus paub. Feem ntau, tom qab ob hnub, cov lus qhia zais no tawm los ntawm cov kua.
Inhalation daim ntawv thov. Trypsin inhalations tau ua tiav los ntawm kev siv lub tshuab nqus pa lossis duab hluav taws xob. Tom qab cov txheej txheem, nws yog qhov zoo dua los yaug koj lub qhov ntswg lossis qhov ncauj nrog dej sov (nyob ntawm seb qhov txheej txheem no tau ua li cas).
Hauv daim ntawv ntawm lub ntsiab muag. Lawv yuav tsum tau nqus dej txhua txhua 6-8 teev nyob rau 3 hnub.
Cov yam ntxwv ntawm kev siv trypsin:
- Trypsin txwv tsis pub siv rau qhov txhab los ntshav.
- Tsis tuaj yeem siv los kho mob qog nqaij hlav, tshwj xeeb tshaj yog muaj mob viav vias.
- Tsis muab tso ncaj nruab nrab.
- Thaum kho cov me nyuam yaus, ib qho kev sib txuam.
- Cov poj niam cev xeeb tub los yog lactating yuav tsum tau noj cov tshuaj no nkaus xwb yog tias qhov kev pheej hmoo ntawm nws txoj kev tuag lossis poj niam hauv plab tuag yuav tseem ceeb heev.
Pharmacokinetics, i.e. kev faib tawm cov tshuaj hauv lub cev tseem tsis tau kawm. Nws tsuas yog paub tias thaum dev nkag mus rau hauv lub cev, trypsin khi rau alpha macroglobulins thiab alpha-1 antitrypsin (nws cov inhibitor).
Tam sim no, muaj ntau qhov zoo ntawm kev tshuaj xyuas txog cov tshuaj muaj trypsin. Tshwj xeeb tshaj plaws ntau yam ntawm nws daim ntawv thov hauv ophthalmology. Nrog nws, hemorrhages, adhesions, inflammatory thiab dystrophic cov txheej txheem ntawm iris tau kho, vim hais tias cov pathologies nyob rau hauv qhov tsis muaj kev kho kom tsim nyog tuaj yeem ua rau tsis pom kev tsis pom kev. Kev sib xyaw ua ke los kho kev kho mob enzyme nrog tshuaj tiv thaiv antiallergic, tshuaj tua kab mob, tshuaj hormones, tshuaj kho lub ntsej muag txhaws yog qhov zoo heev, uas cuam tshuam ntau npaum li cas ntawm cov nqaij ua kom rov ua dua tshiab.
Trypsin pab txo cov kev mob ntawm kev mob sib koom tes, xws li mob caj dab, mob caj dab, mob pob qij txha, thiab mob rheumatic. Nws daws qhov mob, txhawb kev mob, rov qab ua kom tag nrho ntawm kev txav mus los.
Nrog rau kev raug mob sab heev, txiav kom tob, hlawv, cov enzyme tso cai, tsawg kawg, kom txo qis txoj kev noj qab haus huv ntawm tus neeg raug mob, thiab txuas ntxiv kho kom zoo dua.
Tus nqi nruab nrab ntawm trypsin npaj nyob rau hauv Russia yog li ntawm 500 rubles.
Hauv cov ntshav, lub npe hu ua "immunoreactive" trypsin tau txiav txim siab ua ke nrog cov tshuaj uas txwv nws cov kev ua haujlwm - alpha-1-antitrypsin. Tus nqi trypsin yog 1-4 μmol / ml.min. Nws nce ntxiv tuaj yeem pom nyob rau hauv kev kis mob sai sai ntawm kab mob ntawm cov txiav, oncological cov txheej txheem hauv nws, nrog cystic fibrosis, mob raum tsis ua hauj lwm, thiab tseem tuaj yeem nrog cov chav kawm kis kab mob. Qhov ua kom tsawg ntawm cov enzyme yuav qhia tau tias hom 1 mob ntshav qab zib mellitus, lossis cov kabmob sab saud, tab sis ua rau mob ntev thiab tom qab.
Ntxiv rau kev kuaj ntshav, cov neeg mob feem ntau tau kho rau kws kho coprogram. Ua ntej txoj kev tshawb no, 3 tshuaj tua kab mob tsis pom zoo rau 3 hnub. Thaum txiav txim trypsin hauv cov quav yuav tsis pom. Qhov no feem ntau yog ib qho cim ntawm cystic fibrous cov txheej txheem hauv cov txiav. Qhov kev poob qis hauv nws yog pom nrog cystic fibrosis, tab sis qhov no tsis txhais tau tias qhov kev kuaj mob tau lees paub, thiab kev tshawb fawb ntxiv yog xav tau los ua kom pom tseeb. Tam sim no, nws ntseeg tau tias qhov kev txiav txim siab ntawm trypsin kev ua si hauv cov quav pom qhov tsis muaj dab tsi.
Cov lus qhia luv luv ntawm trypsin thiab lwm yam enzymes yog muab hauv video hauv tsab xov xwm no.
