Rosucard hais txog cov statins uas txo qis cov kev sib txuam ntawm cov cholesterol nyob rau hauv cov hlab ntshav. Lub npe thoob ntiaj teb nonproprietary tshuaj yog Rosuvastatin (Rosuvastatin).
Cov tshuaj yog nquag noj rau hauv kev kho mob ntawm hypercholesterolemia, kev tiv thaiv ntawm kev tsim ntawm atherosclerotic plaques thiab hlab plawv pathologies. Tus kws kho mob txiav txim qhov ntau npaum li cas ntawm cov tshuaj raws li qhov mob hnyav thiab tus yam ntxwv ntawm tus neeg mob.
Tshooj lus muaj cov ncauj lus yooj yim hais txog Rosucard (10.20.40 mg), nws tus nqi, kev kuaj xyuas neeg mob thiab analogues.
Daim ntawv thiab cov qauv ntawm cov tshuaj
Rosucard yog suav hais tias yog ib yam tshuaj uas muaj lipid-txo cov nyhuv. Cov nquag tiv thaiv cov khoom lag luam HMG-CoA reductase cov khoom lag luam. Ua tsaug rau cov enzyme no, HMG-CoA hloov pauv mus rau mevalonic acid, uas yog qhov ua ntej ntawm cov roj (cholesterol).
Lub tuam txhab Czech koom haum Zentiva tua cov tshuaj. Rosucard yog tsim nyob rau hauv cov zaj duab xis-ntsiav tshuaj daim ntawv rau kev siv qhov ncauj. Cov ntsiav tshuaj muaj lub teeb xim liab xim, convex nto ntawm ob sab thiab ib hom duab ntev.
Cov tshuaj tiv thaiv nquag ntawm cov tshuaj yog rosuvastatin. 1 lub ntsiav tshuaj ntawm Rosucard yuav muaj 10, 20 lossis 40 mg ntawm cov tshuaj nquag. Ntxiv rau qhov no, cov tshuaj suav nrog cov ntu khoom siv, uas yog:
- crosscarmellose sodium;
- microcrystalline cellulose;
- lactose monohydrate;
- magnesium stearate.
Cov zaj duab xis muaj cov tshuaj xws li talc, macrogol 6000, liab oxide, hypromellose thiab titanium dioxide.
Ib qhov hlwv muaj 10 ntsiav tshuaj. Ntim yog tsim ib qho, peb lossis cuaj lub hlwv. Rosucard ntim ib txwm nrog daim ntawv ntxig rau kev siv lub ntsiav tshuaj.
Tus txheej txheem ntawm kev txiav txim ntawm cov khoom tseem ceeb
Qhov kev ua ntawm rosuvastatin yog tsom kom nce qib ntawm LDL receptors hauv lub hlwb ntawm daim siab parenchyma (hepatocytes). Ib qho kev nce ntawm lawv tus lej ua rau muaj qhov nce ntxiv thiab kev tshaj tawm ntawm LDL, qhov txo qis ntawm VLDL thiab tag nrho cov ntsiab lus ntawm cov "roj" phem.
Cov lipid-txo cov nyhuv ntawm Rosucard nyob ncaj qha rau qhov ntau npaum li cas. Tom qab 1 lub lim tiam ntawm kev noj cov tshuaj, qhov kev txo qis hauv cov roj (cholesterol) siab tau pom, tom qab 2 lub lis piam 90% kev kho mob loj tshaj plaws tau tiav. Txog rau 4 lub lim tiam, kev saib xyuas cov roj cholesterol nyob ntawm ib qib raug pom zoo.
Cov tshuaj pab ua kom nce qib HDL, uas tsis yog atherogenic thiab tsis tso rau hauv daim ntawv ntawm cov quav hniav thiab kev loj hlob ntawm cov phab ntsa ntawm cov hlab ntsha.
Txhua hnub kev tau txais ntawm rosuvastatin tsis hloov pauv qhov pharmacokinetic. Cov tshuaj cuam tshuam nrog cov ntshav protein (tsawg kawg khi rau albumin), kev nqus tshwm sim los ntawm daim siab. Txoj kev tivthaiv tuaj yeem hla lub cev.
Kwv yees li 90% ntawm rosuvastatin raug tshem tawm ntawm lub cev los ntawm txoj hnyuv, qhov ntxiv los ntawm lub raum. Lub chaw muag tshuaj ntawm cov tshuaj tiv thaiv nquag tsis nyob ntawm tub los ntxhais thiab hnub nyoog.
Kev taw qhia thiab contraindications rau siv
Tus kws kho mob sau ntawv rau Rosucard yog tias qhov kev kuaj mob ntawm tus neeg mob cuam tshuam nrog cov roj (cholesterol) ntau ntxiv.
Kev siv tus kheej yog txwv tsis pub siv.
Muaj ntau lub pathologies nyob rau hauv uas ua tsis tau ntawm lipid metabolism tshwm sim.
Kev siv cov ntsiav tshuaj muaj feem xyuam rau:
- Thawj los yog sib xyaw hypercholesterolemia.
- Cov kev kho mob nyuaj ua rau hypertriglyceridemia.
- Familial (keeb kwm) homozygous hypercholesterolemia.
- Ua rau qeeb ntawm kev txhim kho atherosclerosis (ntxiv rau kev noj haus).
- Kev tiv thaiv ntawm cov hlab plawv pathologies tiv thaiv keeb kwm ntawm atherosclerosis (mob plawv, kub siab, mob hlab ntsha tawg thiab mob plawv).
Kev siv cov tshuaj nrog cov koob tshuaj 10 thiab 20 mg yog contraindicated nyob rau hauv:
- lub xub ntiag ntawm ib tug neeg rhiab rau Cheebtsam;
- nqa menyuam lossis pub niam mis;
- tsis ncav lub hnub nyoog 18 xyoo;
- kev txhim kho ntawm myopathy (kab mob neuromuscular);
- ntau txoj kev kho mob nrog cyclosporine;
- nce kev ua si ntawm CPK enzyme los ntawm ntau dua tsib zaug;
- tus poj niam tsis kam lees kev tswj kom txaus;
- daim siab ua haujlwm thiab mob ua haujlwm hauv lub cev ua haujlwm tsis meej;
- cov tswj hwm ntawm cov kab mob HIV protease blockers.
Nws kuj tseem muaj cov npe ntawm cov yam ntxwv ntawm contraindications rau kev noj tshuaj ntawm 40 mg:
- Cov kab mob muaj keeb muaj myopathy.
- Cov cawv thiab cawv ntev mus.
- Mob raum tsis ua hauj lwm.
- Myelotoxicity thaum noj HMG-CoA reductase blockers thiab fibrates.
- Lub qog ua haujlwm tsis zoo.
- Kev siv ua ke ntawm fibrates.
- Cov kab mob sib txawv ua rau muaj kev nce siab ntxiv hauv cov concentration ntawm rosuvastatin hauv cov hlab ntshav.
Nws kuj tseem tsis pom zoo kom siv tshuaj ntau npaum li 40 mg los ntawm cov neeg sawv cev ntawm haiv neeg Mongoloid vim muaj cov yam ntxwv ntawm tus kheej.
Cov lus qhia rau kev siv tshuaj
Cov ntsiav tshuaj tsis tas yuav tsum tau tom lossis ntxo, lawv tau nqos nrog dej. Kev noj tshuaj tsis yog nyob ntawm lub sijhawm ntawm hnub lossis kev noj zaub mov.
Ua ntej sau ntawv tawm Rosucard, tus kws kho mob tau pom zoo kom tus neeg mob ua raws li kev noj haus uas yog txhawm rau txo cov roj cholesterol kom tsawg.
Kev muab tshuaj thawj zaug rau txhua hnub yog 0.5-1 ntsiav tshuaj (5-10 mg). Tom qab plaub lub lis piam, cov koob tshuaj yuav nce tau los ntawm kws kho mob. Ib qho kev nce ntxiv ntawm kev noj tshuaj txhua hnub rau 40 mg yog ua tau tsuas yog thaum muaj ntshav ntau dhau thiab muaj qhov tshwm sim ntau ntawm cov teeb meem ntawm cov hlab plawv, thaum ib koob tshuaj 20 mg txhua hnub ua tsis tau zoo.
Cov lus hauv qab no qhia cov yam ntxwv ntawm kev siv ntawm Rosucard nyob rau hauv cov neeg ntawm haiv neeg Mongoloid, nrog pathologies ntawm biliary system thiab neuromuscular cuam tshuam.
| Kab mob / mob | Nta ntawm kev noj tshuaj |
| Daim siab ua haujlwm | Yog tias nws tshaj li 7 lub ntsiab lus, nws yog qhov tsim nyog los kho lub koob tshuaj ntawm cov tshuaj. |
| Tsis hlauv | Qhov tsuas pub noj yog 5-10 mg ib hnub twg. Nrog rau cov hnub nyoog nruab nrab, 40 mg ib hnub yuav tsum tsis txhob noj, nrog qhov tsis txaus ntseeg, rosuvastatin yog txwv tsis pub. |
| Yuav muaj myopathy | Cov neeg mob tau tso cai kom noj 10-20 mg ntawm cov tshuaj. Ib koob tshuaj ntawm 40 mg yog contraindicated nyob rau hauv no predisposition. |
| Moob Leeg | Kev coj ua txhua hnub ntawm cov tshuaj yog 5-10 mg. Txhawb tshuaj ntau ntxiv yog txwv tsis pub ua. |
Txee lub neej yog 24 lub hlis, tom qab lub sijhawm no, kev noj tshuaj yog qhov txwv me me. Ntim tau khaws cia kom deb ntawm cov menyuam yaus ntawm qhov kub txog 25 ° C.
Kev phiv tshuaj thiab kev haus ntau dhau
Ib qho kev tshwm sim tshwm sim tuaj yeem tshwm sim thaum noj cov tshuaj.
Yog tias muaj qhov tshwm sim tsis zoo, tus neeg mob yuav tsum tsis txhob siv Rosucard thiab sab laj ib tus kws kho mob.
Kev phiv los sis ncaj qha nyob ntawm qhov ntau npaum li cas ntawm cov tshuaj, yog li ntawd, nws yog feem ntau pom vim kev tswj hwm ntawm cov ntsiav tshuaj nrog ntau npaum li 40 mg.
Cov kev qhia muaj cov ncauj lus nram qab no txog cov xwm txheej tsis zoo:
- Dyspeptic cuam tshuam - tawm tsam xeev ntuav thiab ntuav, mob nyob rau hauv thaj chaw epigastric, qee zaum kev txhim kho ntawm pancreatitis thiab mob siab.
- Cov tshuaj tiv thaiv genitourinary - proteinuria (muaj protein nyob hauv zis), hematuria (muaj ntshav nyob hauv cov zis).
- Ua xua tshwm sim - khaus, tawm pob rau ntawm daim tawv nqaij, urticaria.
- Kev mob hlwb ntawm cov leeg nqaij - mob nqaij pob txha, mob nqaij pob txha, ua rau cov leeg mob.
- CNS kawg - ntu mob caj dab, tsaus muag, pw tsis tsaug zog thiab npau suav phem, kev nyuaj siab.
- Kev ua txhaum ntawm kev ua me tub me nyuam - qhov kev loj hlob ntawm cov qog mammary hauv cov txiv neej.
- Cov tawv nqaij thiab nqaij mos ua kom lub cev tawv nqaij yog Stevens-Johnson syndrome (los yog daim tawv nqaij mob ua paug).
- Kev cuam tshuam nyob rau hauv endocrine system - kev txhim kho ntawm cov tsis-insulin-mob ntshav qab zib mellitus hom II.
- Ua tsis taus pa - hnoos qhuav thiab ua tsis taus pa.
Txij li thaum pharmacokinetics ntawm cov tshuaj ua kom nquag plias tsis yog koob tshuaj-siv, ib qho kev siv ntau dhau tsis tsim. Qee zaum nws tuaj yeem nce cov cim ntawm qhov tshwm sim tsis zoo.
Kev Kho mob suav nrog kev ntsuas xws li mob plab, siv ntawm sorbents thiab tshem tawm cov tsos mob.
Sib xyaw nrog lwm yam tshuaj
Qhov sib xyaw ntawm Rosucard nrog qee cov tshuaj tuaj yeem ua rau txo qis lossis hloov dua tshiab ntxiv qhov ua tau zoo ntawm cov tshuaj nquag, nrog rau qhov tshwm sim ntawm cov kev mob tshwm sim.
Txhawm rau tiv thaiv nws tus kheej los ntawm kev tsis zoo, tus neeg mob yuav tsum qhia tus kws kho mob txog txhua yam kab mob thiab ua raws li kev noj tshuaj.
Hauv qab no yog cov kab ntawv muaj cov npe tshuaj uas ua tiav ib lub sijhawm tswj hwm nce lossis txo qis kho nyhuv ntawm Rosucard.
| Txhim khu cov nyhuv | Txo cov nyhuv |
| Cyclosporin (ib qho tshuaj tiv thaiv muaj zog). Nicotinic acid HIV tiv thaiv kabmob. Cov Txheej Txheem. Gemfibrozil thiab lwm yam fibrates. | Erythromycin (tshuaj tua kab mob los ntawm chav kawm macrolide). Tshuaj tua kab mob, nrog rau txhuas thiab magnesium hydroxide. |
Muaj cov ntaub ntawv hais tias nrog kev noj haus nyuaj ntawm Rosucard nrog Warfarin thiab lwm cov vitamin K kev thaiv kev phem, kev txo qis hauv INR yog qhov ua tau.
Hauv chav kawm txog kev sim tshuaj, tsis muaj tshuaj lom neeg cov tshuaj tiv thaiv tau pom ntawm cov khoom sib xyaw ntawm Rosucard thiab Ketoconazole, Fluconazole, Itraconazole, Digoxin, Ezetimibe.
Nws yog txwv tsis pub noj cov tshuaj thiab dej cawv tib lub sijhawm. Zam kev haus cawv thiab haus luam yeeb pab txo qis cov roj cholesterol kom txaus.
Tus nqi thiab tus neeg mob lub tswv yim
Txij li thaum Rosucard yog ib qho tshuaj siv txawv teb, nws tus nqi yog siab heev. Txawm hais tias qhov ua tau zoo ntawm cov tshuaj, nws tus nqi tseem yog qhov tseem ceeb drawback.
Qhov nruab nrab, Rosucard 10 mg (30 ntsiav tshuaj) tuaj yeem muas ntawm tus nqi ntawm 595 rubles, 20 mg rau 875 rubles, 40 mg rau 1155 rubles. Txuag koj cov nyiaj, koj tuaj yeem tso online hauv lub vev xaib ntawm cov neeg sawv cev cai.
Cov neeg mob feem ntau pom tias muaj txiaj ntsig zoo los ntawm kev noj tshuaj. Lub ntsiab zoo yog daim ntawv tshuaj yooj yim thiab qhov xav tau tsuas yog siv 1 zaug nyob rau ib hnub.
Txawm li cas los xij, kev tshuaj xyuas tsis zoo ntawm cov neeg mob kuj tseem tuaj yeem pom hauv Is Taws Nem.
Cov kws kho mob thiab kws kho plawv sib txuas cov kev mob tsis zoo nrog kev txhaj tshuaj loj. Uas yog tus kws kho mob N.S. hais Yakimets:
"Kuv tau txheeb xyuas qhov ua tau zoo ntawm qhov tsis tseem ceeb no - nws txig rau cov lipid metabolism hauv cov txheej txheem uas tsis ua kom yuag thiab tsis ua haujlwm me, ntxiv rau nws yog qhov raug nqi, hauv kev piv nrog Krestor. Muaj cov kev mob tshwm sim, tab sis lawv tsis tshua muaj teeb meem, vim kuv muab tshuaj rau 5-10 mg rau kev kuaj mob me."
Cov lus ua piv txwv thiab analogues tshuaj
Hauv qhov xwm txheej uas tus neeg mob raug txwv tsis pub noj Rosucard vim yog contraindications lossis phiv, tus kws kho mob xaiv qhov hloov zoo.
Ntawm kev lag luam pharmacological koj tuaj yeem nrhiav ntau cov lus ntawm cov tshuaj, uas muaj tib lub nquag ua haujlwm. Ntawm lawv yog:
- Rosuvastatin;
- Neeg Coob
- Rosistark;
- Tevastor
- Akorta;
- Roxer;
- Hlua
- Mertenyl;
- Hlob.
Nws kuj tseem muaj cov lus piv txwv uas sib txawv hauv cov ntsiab lus ntawm cov tshuaj nquag, tab sis suav nrog hauv pawg ntawm statins:
- Zokor.
- Atoris.
- Vasilip
Zokor. Nrog rau cov khoom xyaw nquag simvastatin, uas suppresses HMG-CoA reductase. Ua los ntawm cov tuam txhab lag luam pharmacological hauv Asmeskas thiab Netherlands. Tus nqi nruab nrab ntawm kev ntim khoom (No. 28 10mg) yog 385 rubles.
Atoris. Qhov no yog qhov pheej yig dua ntawm Rosucard, vim hais tias tus nqi ntawm kev ntim khoom (No. 30 10mg) yog 330 rubles. Cov tshuaj yeeb tshuaj yog atorvastatin, uas ua rau kom qhov kev ua haujlwm ntawm LDL ntau ntxiv nyob rau hauv daim siab thiab cov ntaub so ntswg ntxiv.
Vasilip. Cov tshuaj muaj simvastatin hauv kev txiav txim siab ntawm 10.20 thiab 40 milligrams. Nws muaj tib yam qhia thiab contraindications li Rosucard. Cov tshuaj yuav tuaj yeem yuav rau tsuas yog 250 rubles (Zauv 28 10mg).
Hais txog cov tshuaj raws li rosuvastatin tau piav qhia hauv daim video hauv kab lus no.
