Desmopressin yog tshuaj pleev ib ce ntawm vasopressin. Cov tshuaj tsis muaj cov tshuaj lom neeg lub cev tsis zoo, tsis yog hloov pauv. Thov tom qab sab laj nrog kws kho mob; kev noj tshuaj rau tus kheej tuaj yeem cuam tshuam kev noj qab haus huv thiab lub neej ntawm tus neeg mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Cov tshuaj tsis raug lub npe ntawm cov tshuaj yog Desmopressin. Hauv Latin - Desmopressin.
Desmopressin yog tshuaj pleev ib ce ntawm vasopressin.
Ath
Tus lej tshuaj yog H01BA02.
Daim ntawv tso tawm
Cov tshuaj yog tsim nyob rau hauv ntau version. Ua ntej koj xaiv daim ntawv, koj yuav tsum sab laj nrog koj tus kws kho mob kom nrhiav tau qhov tsim nyog rau kev kho mob.
Kev daws rau kev txhaj tshuaj yog muab cov tshuaj intramuscularly, intravenously, subcutaneously.
Ntsiav tshuaj
Cov tshuaj muaj nyob rau hauv daim ntawv dawb, puag ncig ntsiav tshuaj. Ntawm ib sab yog cov sau "D1" lossis "D2". On thib ob sib faib sawb. Ntxiv nrog rau cov kev ua kom nquag plias, desmopressin, cov muaj pes tsawg leeg suav nrog magnesium stearate, cov hmoov txhuv nplej siab, povidone-K30, lactose monohydrate.
Cov tshuaj muaj nyob rau hauv daim ntawv dawb, puag ncig ntsiav tshuaj.
Ncos
Nasal tee yog kua tsis muaj kob. Excipients yog chlorobutanol, sodium tshuaj dawb, dej, hydrochloric acid. Muab koob tshuaj 0.1 mg rau 1 ml.
Txau
Nws yog cov kua ntshiab. Ntim hauv lub raj mis tshwj xeeb nrog cov tshuaj dispenser. Excipients yog poov tshuaj sorbate, dej, hydrochloric acid, sodium tshuaj dawb.
Mechanism ntawm kev ua
Cov tshuaj muaj cov antidiuretic zoo rau tib neeg lub cev.
Cov tshuaj ua haujlwm nquag yog hloov kho ntawm ib lub zog ntawm cov tshuaj hormones vasopressin. Thaum cov tshuaj nkag mus rau hauv lub cev, cov txais tshwj xeeb tau qhib, vim tias cov txheej txheem ntawm cov dej tso rov ua kom tau zoo dua. Cov ntshav coagulation zoo tuaj.
Hauv cov neeg mob hemophilia, cov tshuaj nce ntxiv ntawm coagulation 8 los ntawm 3-4 zaug. Ib qho kev nce ntxiv ntawm plasminogen hauv cov ntshav ntshav tau sau tseg.
Kev tswj fwm tso cai rau koj kom ua tiav cov nyhuv.
Cov tshuaj txhim kho cov ntshav coagulation.
Cov Tshuaj Pharmacokinetics
Cov tshuaj yaj yeeb nyob rau hauv lub siab. Nws yog muab tshem tawm nrog zis.
Kev tshem tawm ib nrab-lub neej ua rau 75 feeb. Tib lub sijhawm, tom qab ob peb teev, kev pom tseeb ntau ntawm cov tshuaj hauv tus neeg mob cov ntshav tau sau tseg. Qhov siab tshaj plaws tau pom zoo yog 1.5-2 teev tom qab kev tswj hwm.
Kev ntsuas rau siv
Cov tshuaj yog kws kho rau cov mob polyuria, rau kev kho mob ntshav qab zib insipidus, rau mob hnoos qeev, hemophilia, kab mob von Willebrand. Txau thiab tee siv yog ib feem ntawm txoj kev kho mob rau tus mob nocturnal enuresis, tso zis tsis tso zis. Tsis tas li ntawd, tee tau siv tom qab ua haujlwm ntawm lub qog pituitary.
Cov Yuav Tsum Muaj
Nws yog txwv tsis pub kho nrog desmopressin rau kev mob anuria, muaj ib qho kev tsis haum tshuaj, ib leeg tsis kam rau cov tshuaj ntawm cov tshuaj, thiab rau plasma hypoosmolality. Cov tshuaj tsis yog siv rau polydipsia, dej tuav cia, lub plawv tsis ua haujlwm. Cov tshuaj tsis tau muab tshuaj rau txoj hlab ntaws tsis khov thiab hom 2 von Willebrand kab mob.
Cov tshuaj tsis tau tswj kav dej nrog lub siab tsis khov.
Nrog saib xyuas
Thaum muaj kev ua txhaum ntawm cov dej-electrolyte tshuav, zais zis ntawm cov leeg, kab mob ntawm cov hlab plawv ntshav lossis lub raum, muaj kev pheej hmoo ntawm kev mob siab intracranial, yuav tsum ceev faj thaum siv tshuaj kho. Ib tug txheeb ze sib cog lus pom tau tias muaj hnub nyoog tshaj 65 xyoos.
Yuav ua li cas coj Desmopressin
Cov koob tshuaj thiab ntau npaum li cas yog nyob ntawm tus kabmob, tus yam ntxwv ntawm tus neeg mob. Lawv yuav tsum raug xaiv ua ke nrog tus kws kho mob. Koj yuav tsum paub koj tus kheej nrog cov lus qhia rau siv.
Qhov muab tshuaj rau thawj lub qhov ntswg, cov tshuaj tsuag nws txawv ntawm 10 txog 40 mcg ib hnub. Nws yuav tsum noj ob peb zaug. Cov me nyuam 12 xyoos rov hauv yuav tau hloov kho. Rau lawv, ib koob tshuaj 5 txog 30 micrograms yog xaiv thaum nruab hnub.
Nrog cov lus qhia ntawm kev txhaj tshuaj rau cov neeg laus, qhov tshuaj yog los ntawm 1 txog 4 μg rau ib phaus ntawm lub cev hnyav. Hauv thaum yau, 0.4-2 micrograms yuav tsum tau tswj hwm.
Yog tias txoj kev kho tsis nqa cov nyhuv uas xav tau nyob rau hauv ib lub lis piam, cov koob tshuaj yuav tau hloov kho.
Yog tias txoj kev kho tsis nqa cov nyhuv uas xav tau nyob rau hauv ib lub lis piam, cov koob tshuaj yuav tau hloov kho.
Nrog ntshav qab zib
Cov tshuaj yuav tsum tau siv nrog ceev faj thiab tsuas yog qhia los ntawm tus kws kho mob tuaj koom.
Sab sij huam
Kiv taub hau, mob taub hau, yuav tsis meej pem. Tsis tshua muaj ntau, cov neeg mob poob mus rau hauv coma. Lub cev hnyav tuaj yeem nce ntxiv, rhinitis yuav tshwm sim. Hauv qee tus neeg mob, cov kab mob plab ntawm lub qhov ntswg tau o. Ntuav, xeev siab, thiab mob plab yog tau. Ntshav siab tuaj yeem nce lossis poob qis. Qee zaum oliguria, kub tso xim, kev fab tshuaj tshwm sim. Mob Hyponatremia yuav tshwm sim. Thaum siv kev txhaj tshuaj, qhov mob tuaj yeem pom nyob ntawm thaj chaw txhaj tshuaj. Yog tias cov tshuaj raug siv los kho menyuam yaus hnub nyoog qis dua 12 hli, mob tau qaug dab peg.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Kev siv cov tshuaj tsis cuam tshuam rau kev muaj peev xwm tsav tsheb.
Cov lus qhia tshwj xeeb
Qee cov neeg yuav tsum ua raws cov lus qhia tshwj xeeb.
Siv rau lub sijhawm qub
Tom qab 65 xyoo, kev ceev faj yuav tsum tau siv thaum siv cov tshuaj.
Xaj Desmopressin rau Cov Menyuam
Nws tuaj yeem siv los kho menyuam yaus txij li 3 hlis. Yuav tsum txhaj koob kho kom haum.
Siv thaum cev xeeb tub thiab lactation
Nws yog siv nrog ceev faj. Txoj kev kho yog nqa tawm los ntawm kev saib xyuas tas li ntawm tus kws kho mob.
Thaum cev xeeb tub, cov tshuaj siv nrog ceev faj.
Noj ntau dhau
Cov tsos mob yog hyponatremia, npliag cia. Txhawm rau tshem tawm qhov mob, kev siv tshuaj diuretics raug siv, ib qho kev daws teeb meem tshwj xeeb yog tswj hwm.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv tib lub sijhawm nrog dopamine muaj cov neeg sawv cev, cov nyhuv nias tau kho kom zoo. Lithium carbonate tsis muaj zog cov nyhuv ntawm cov tshuaj. Ceev faj yuav tsum tau ua thaum ua ke nrog cov tshuaj nrog tshuaj uas ua rau muaj kev tawm tsam antidiuretic hormone.
Cawv tau zoo
Kev haus dej haus cawv thaum siv tshuaj kho tsis pom zoo, vim tias nws ua rau cov tshuaj siv tshuaj tsawg dua.
Analogs
Cov tshuaj muaj coob tus ntawm cov lus ua. Cov qauv tshuaj yog cov ntsiav tshuaj Minirin, Nativa, Adiuretin, Tshuaj txau Presayneks, Vasomirin. Desmopressin Acetate kuj tseem siv. Muaj lwm cov tshuaj ntsiav, ntsiav tshuaj thiab cov kev daws teeb meem uas muaj cov khoom antidiuretic. Tej zaum siv cov tshuaj kho mob rau pej xeem.
Minirin yog qhov piv txwv ntawm Desmopressin.
Tsev Khw Tshav Puam Desmopressin Nyiaj so koobtsheej
Koj tuaj yeem yuav cov tshuaj hauv txhua lub tsev muag tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Nws yog tsis yooj yim sua los yuav ib cov tshuaj uas tsis muaj tshuaj.
Desmopressin Nqe
Tus nqi sib txawv nyob rau ntau thaj tsam, chaw muag tshuaj. Qhov ntsuas tseem nyob ntawm seb cov tshuaj uas ib tus neeg noj. Koj tuaj yeem yuav cov tee rau li ntawm 2,400 rubles, koj yuav tsum them nyiaj ntxiv rau kev txhaj tshuaj.
Cia rau cov neeg mob rau cov tshuaj
Khaws cov tshuaj rau hauv qhov chaw uas tsis ncav cuag rau cov menyuam yaus, qhov kub uas tsis pub tshaj 30 degrees.
Khaws cov tshuaj cia kom deb ntawm cov menyuam yaus.
Hnub tas sij hawm
Cov tshuaj yeeb yaj kiab tuaj yeem siv rau 2.5 xyoo. Thaum lub sijhawm no tas sijhawm, cov khoom yuav tsum muab pov tseg. Kev siv cov tshuaj uas tas sij hawm yog txwv tsis pub.
Desmopressin Chaw tsim tshuaj paus
Cov tshuaj yog tsim nyob hauv Iceland.
Kev txheeb xyuas ntawm Desmopressin
Cov tshuaj tau txais ntau ntawm cov tshuaj xyuas zoo.
Cov kws kho mob
Anatoly, 38 xyoo, Pskov: “Kuv feem ntau muab tshuaj rau cov neeg mob, vim tias cov kev mob tshwm sim tsis tshua pom tshwm, cov tshuaj tsis muaj tshuaj lom, muaj peev xwm tiv thaiv cov kab mob. hnub, cov nyhuv tshwm. "
Cov tshuaj yog siv rau thawj tus kabmob nocturnal enuresis.
Cov neeg mob
Denis, hnub nyoog 36 xyoo, Khabarovsk: "Thaum kuv tus tub muaj 5 xyoos, muaj txaj pw. Lawv tau sim tshuaj sib txawv, lwm txoj kev xaiv, tab sis tsis muaj dab tsi pab. Tus kws kho mob tau muab tshuaj rau Desmopressin kho. Cov txiaj ntsig tsis tshwm sim los ntawm thawj lub lis piam, tab sis txoj kev hais daws tau pab. tshwm sim. "
Anna, muaj 28 xyoo, Vologda: "Thaum mus kuaj mob tas li, lub chaw kuaj mob tau kuaj pom tias mob ntshav qab zib insipidus. Kuv tau mus rau lwm tus kws kho mob, cia siab tias muaj qhov ua yuam kev. Tus kws kho mob tau lees paub qhov kev kuaj mob thiab qhia Desmopressin. Nws pib zoo, nws nqhis dej ploj mus thaum hmo ntuj. kim, tab sis tam sim no koj yuav tsum haus nws tas li. "
