Cov kua nplaum - cov lus qhia rau kev siv, muaj pes tsawg leeg, tso tawm daim ntawv

Glucophage yog cov tshuaj niaj hnub los ntawm cov pab pawg biguanide. Cov tshuaj yog siv rau hauv endocrinology rau kev kho mob ntshav qab zib hom 2.

Cov ntsiav tshuaj tau txais nrog mob ntshav qab zib rau kev tiv thaiv lub hom phiaj. Nws yog ib qho tseem ceeb uas yuav tsum xaiv cov qib ntsuas txhua hnub kom zoo kom tsis txhob muaj kev phiv tshuaj rau cov piam thaj.

Cov lus qhia rau kev siv yuav tsum kawm ua ntej pib txoj kev kho.

Muaj pes tsawg leeg

Metformin hydrochloride yog cov tshuaj nquag ntawm cov tshuaj. Lub ntsiab tivthaiv ua rau cov ntshav qab zib, tswj lub cev nyhav ntawm cov ntshav qab zib.

• metformin hydrochloride - 500, 800 mg thiab 1000 mg;
• magnesium stearate - 1 Ntsiav tshuaj ntsiav muaj 5, 8.5 thiab 10 mg ntawm ib qho khoom ntxiv, ntsig txog;
• povidone - tus nqi hauv 1 ntsiav tshuaj ntawm 20, 34 thiab 40 mg, nyob rau theem ntawm metformin;
• cov zaj duab xis membrane muaj hypermellose hauv kev sib xyaw nrog 500 lossis 850 mg ntawm metformin lossis opadray ntshiab hauv ntsiav tshuaj 1000 mg glucofage.

Daim ntawv tso tawm thiab ntim khoom

Cov tshuaj ntawm cov pab pawg biguanide raws li metformin yog puag ncig dawb ntsiav tshuaj hauv cov zaj duab xis txheej, cov duab yog biconvex. Cov khw muag tshuaj saw tau txais tus neeg sawv cev antihyperglycemic hauv ib pob 30 lossis 60 ntsiav tshuaj. Tus neeg sawv cev tshuaj tiv thaiv kab mob ua tau zoo hauv Spain - lub tuam txhab kev lag luam tshuaj Merck, SL thiab Fabkis - lub tuam txhab Merck Sante.

Pharmacological kev txiav txim

Noj cov tshuaj Glucophage stabilizes cov mob ntawm cov neeg mob uas kuaj pom tus mob ntshav qab zib hom 2. Cov kev xav tsis zoo rau cov tshuaj metformin los ntawm cov plab hnyuv siab raum thiab cov kab ke raug pom muaj nyob rau hauv, cov kev qhia tsis pom ploj tom qab ob peb hnub.

Cov tshuaj glucophage lub sijhawm ntev ua

Pharmacokinetics thiab cov chaw muag tshuaj

Cov khoom tseem ceeb ntawm metformin:

• zoo ntxim rau lipid metabolism;
• tiv thaiv kev hloov ntawm kev mob ntshav qab zib mus rau hauv ntau hom mob hnyav ntawm pathology - ntshav qab zib mellitus;
• txo cov concentration ntawm cov piam thaj hauv lub cev ua ntej thiab tom qab noj mov;
• stabilizes lossis me ntsis txo lub cev hnyav;
• txo qhov feem pua ​​ntawm cov piam thaj nyob hauv cov ntshav hlwb;
• txo qhov concentration ntawm cov roj "tsis zoo";
• activates peripheral qabzib cov paug;
• tsis cuam tshuam rau tsim khoom ntawm lub zog insulin;
• txo cov piam thaj nqus kev nrawm;
• normalizes ntaub so ntswg rhiab rau insulin.

Glucofage 1000 mg

Metformin nquag nqus, tom qab noj tshuaj, qhov siab tshaj plaws nyob rau hauv cov ntshav tau sau tseg tom qab 2.5 teev. Cov kev tivthaiv sai sai nkag mus rau ntau qhov chaw ntawm lub cev, kev noj qab haus huv - nyob rau theem ntawm 60%.

Qhov seem ntawm cov khoom muaj sia nyob nrog cov quav hauv daim ntawv tsis hloov. Qhov kev tshem tawm ib nrab-lub neej yog 6-6.5 teev.

Kev ntsuas rau siv

Cov tshuaj Glucophage yog tswj rau cov ntshav qab zib:

• cov menyuam yaus txij thaum 10 xyoo rov hauv thiab cov tub ntxhais hluas ua qhov tseem ceeb los ntxiv rau txoj kev sib xyaw nrog cov tshuaj insulin;
• txhawm rau tswj lub cev qhov hnyav tawm tsam tom qab ntawm qhov kev ua kom tsis muaj zog los ntawm kev ua haujlwm lub cev thiab kev noj haus;
• kom txo qhov kev pheej hmoo ntawm kev phiv phom sij rau cov neeg mob ntshav qab zib;
• raws li cov tshuaj kab thawj zaug los yog ua tshuaj txuas rau cov ntshav qab zib tsis muaj tshuaj tua kab mob ntshav qab zib rau cov laus.

Cov lus qhia rau kev siv Glucofage

Cov neeg laus tau txais 1 ntsiav tshuaj ntawm cov tshuaj (tsis pub dhau 850 mg rau ib hnub).

Qeb theem pib txog li ob asthiv. Tom ntej no, koj yuav tsum pub ntshav cov ntshav qab zib, kom tus endocrinologist kho cov koob tshuaj.

Kev tso cai ntau tshaj plaws txhua hnub yog 3000 mg ntawm metformin, yuav tsum muaj peb koob tshuaj.

Nrog rau kev sib xyaw ua ke (Glucofage + insulin), tus neeg mob tau txais 1 ntsiav tshuaj ntawm cov tshuaj tiv thaiv kev puas tsuaj (noj ntau npaum li 850 lossis 500 mg ntawm metformin).

Cov Yuav Tsum Muaj

Glucophage ntsiav tshuaj tsis yog kws kho rau cov kab mob thiab kev mob hauv qab no:

• mob raum thiab mob raum;
• kuaj mob ntshav qab zib;
• qhov tshuaj tiv thaiv tsis zoo ntawm lub cev mus rau metformin lossis ntu sib xyaw;
• pathologies, tawm tsam cov keeb kwm yav dhau los uas oxygen tshaib plab ntawm cov ntaub so ntswg txhim kho;
• poob siab hauv lub xeev, lub cev qhuav dej, muaj cov kab mob sib kis loj uas ua txhaum kev khiav haujlwm;
• kev haus dej cawv, kab mob siab ntsws, haus dej cawv.

Thaum cev xeeb tub thiab lactation

Qhov kev xaiv zoo tshaj plaws yog los hloov cov metformin nrog cov tshuaj insulin rau. Nrog rau cov kev xaiv kho no, qhov kev pheej hmoo ntawm kev tsim kab mob ntshav qab zib hauv lub ntsej muag tau raug txo qis dua, thiab kev pheej hmoo ntawm kev tsis sib xws hauv kev txhim kho me nyuam hauv plab yog txo qis. Muaj qee qhov xwm txheej ntawm kev siv cov tshuaj Glucofage thaum cev xeeb tub, tab sis endocrinologist tsis pom zoo kom tau txais cov tshuaj metformin: cov txiaj ntsig ntawm cov tshuaj nquag rau ntawm tus menyuam thiab cov txheej txheem yug menyuam tsis tau kawm ntau.

Rau menyuam

Hauv kev xyaum rau cov menyuam yaus, glucophage tau siv txij li 10 xyoo.

Qhov pib ua txhua hnub yog 500, nrog kev thev taus zoo - 850 mg ntawm metformin ua ntej noj mov lossis tom qab noj mov.

Kev tswj xyuas cov piam thaj hauv qib 10-16 hnub yog xav tau.

Tom qab qhov kawg ntawm lub sij hawm, tus endocrinologist kho cov tshuaj noj (maj mam nce tus nqi ntawm metformin), nce txog qhov ntau tshaj 2000 mg ib hnub.

Qhov nce ntxiv ntawm cov tshuaj yuav tsum tau nyob hauv ob mus rau peb koob.

Hnub nyoog laus

Thaum muaj hnub nyoog 60 xyoo thiab laus dua, ob lub raum feem ntau tsis ua haujlwm zoo, pathologies ntawm lub plawv thiab daim siab. Thaum sau tshuaj rau qhov muaj pes tsawg leeg ua kom yuag, ua kom lub cev tsis muaj ntshav qab zib nyob hauv cov neeg mob ntshav qab zib, koj yuav tsum maj mam nce cov tshuaj rau niaj hnub noj, raws li koj tus kws kho mob hais, qhia txog kev tsim kom muaj qhov tsis zoo, cov ntshav ua kom lub siab, thiab ua ib qho ECG.

Sab sij huam

Thaum pib theem ntawm kev kho, kev tsis zoo rau cov tshuaj metformin yog ua tau.

Feem ntau, cov neeg mob yws yws vim tsis qab los noj mov, xeev siab, mob hauv plab, ntuav, thiab tso quav.

Ntau lub ntsej muag saj tsis haum.

Tom qab ob peb hnub, qhov kev pom tsis zoo yuav tsis muaj zog, tom qab ntawd ploj mus.

Txhawm rau kom txo lub zog ntawm qhov tsis xav tawm, cov kws kho mob pom zoo kom faib cov kua nplaum txhua hnub los ntawm ob mus rau peb zaug. Cov koob tshuaj thawj zaug yuav tsum tau qis dua li tus qauv: yog li cov neeg mob tuaj yeem tiv taus siab dua qhov kev txiav txim ntawm metformin.

Lwm yam kev phiv tsis tshua tshwm sim:

• kev ua xua nrog cov tsos mob ntawm daim tawv nqaij;
• kev hloov pauv hauv theem ntawm daim siab enzymes;
• kab mob siab.

Tsis tas li, kev ua pa yog qhov txawv txav, tsis xis nyob tshwm sim hauv lub plab. Nws yog ib qho tseem ceeb kom sab laj nrog endocrinologist kom ncav sijhawm thaum cov tsos mob ntawm tus kab mob hnyav tshwm sim tuaj: qhov tshwm sim ntawm kev tuag yog ua tau. Feem ntau, mob lactic acidosis mob raum ua rau mob raum.

Kev cuam tshuam nrog lwm yam tshuaj

• Nws yog qhov tsis tsim nyog los ua ke glucophage nrog cov sib txuas uas txo cov ntshav qab zib: hypoglycemia yuav tshwm sim;
• lactic acid lactic acidosis feem ntau txhim kho nrog kev sib xyaw ntawm cov tshuaj tiv thaiv kab mob nrog cov voj diuretics;
• iodine-muaj cov tshuaj tsis raug cai rau kev kuaj mob nrog kev sib piv: kev pheej hmoo ntawm lub raum puas tsuaj thiab lactic acidosis nce ntxiv.

Cawv kev sib tham

Nws yog txwv tsis pub coj cov ntsiav tshuaj Glucofage nrog cov dej cawv, siv thaum muaj tshuaj lom nrog ethyl cawv.

Kev ua txhaum ntawm cov lus pom zoo ua rau lactic acidosis, tshwj xeeb tshaj yog tiv thaiv keeb kwm ntawm daim siab mob siab thiab lub siab ntev.

Txhawm rau tshem tawm txoj kev loj hlob ntawm kev phiv tsis zoo, nws yog txwv tsis pub txais tsis tsuas cawv, tab sis kuj muaj cov tshuaj muaj cawv.

Cov lus qhia tshwj xeeb

Nws yog ib qho tseem ceeb uas them sai sai rau cov ntsiab lus hauv qab no:

• hauv kev raum tsis ua haujlwm, kev tshem tawm creatinine yuav tsum ntsuas ua ntej kho thiab thaum kho;
• Glucophage ntsiav tshuaj raug muab txiav tawm 2 hnub ua ntej kev phais mob. Kev pib rov qab los ntawm kev kho mob raws li metformin yog ua tau nrog kev kho kom zoo dua qub, tom qab 48 teev tom qab phais;
• cov nquag tivthaiv tsis ua txhaum lub nrawm nrawm ntawm psychomotor cov tshuaj tiv thaiv, qhov tsom ntawm kev saib xyuas tseem nyob rau theem ib txwm;
• hauv cov kab mob hauv lub plawv mob hnyav, txoj kev tswj hwm ntawm Glucofage raug tso cai rau kev soj ntsuam tas li ntawm txoj haujlwm ntawm lub plawv thiab lub raum.

Cov nqe lus ntawm kev muag khoom

Cov tshuaj ntawm cov pab pawg biguanide yog daim ntawv yuav tshuaj. Kev tswj tsis tau cov ntsiav tshuaj Glucophage tuaj yeem ua rau muaj qhov txaus ntshai: lactic acidosis. Yuav tsum tau sab laj ntawm tus kws endocrinologist kom xaiv qhov zoo tshaj plaws thaum pib thiab nruab nrab txhua hnub metformin tus nqi.

Cia rau cov neeg mob

Tsis muaj qee cov cai tshwj xeeb los tswj cov khoom kho kom zoo ntawm Glucophage. Nws yog txaus kom ua raws li cov lus pom zoo: chav ntsuas kub, tsis muaj dampness hauv chav. Cov ntsiav tshuaj ntawm cov tshuaj txo qis ntshav qab zib yuav tsum tsis txhob ncav cuag cov menyuam yaus.

Hnub tas sij hawm

Raws li cov lus qhia, Glucofage ntsiav tshuaj ntawm 500 thiab 850 mg yog qhov tsim nyog siv rau tsib xyoos. Nrog rau kev sib txuam ntau dua ntawm metformin (1000 mg), lub txee lub neej txo mus rau peb xyoos.

Nqe thiab yuav khoom rau qhov twg

Tus nqi nruab nrab yog nyob ntawm cov ntsiab lus ntawm metformin thiab cov ntsiav tshuaj. Kwv yees tus nqi ntawm cov tshuaj Glucofage: ntim No. 30 - los ntawm 120 txog 190 rubles; No. 60 - los ntawm 195 txog 270 rubles.

Analogs

Txhawm rau kom cov ntshav qab zib nyob rau hauv cov ntshav qab zib, endocrinologist tuaj yeem muab tus neeg mob lwm hom antihyperglycemic tus neeg sawv cev. Ib qho tshuaj tiv thaiv kab mob tau muab rau tsis haum rau cov ntsiav tshuaj Glucophage.

1. Diaformin.
2. Glycomet.
3. Bagomet.
4. Neeg tsis mloog lus.
5. Meglucon.
6. Tefor.
7. Nyab Xeeb.

Xyuas

Cov neeg mob lub tswv yim hais txog kev ua ntawm metformin yog qhov sib txawv: kev txheeb xyuas nyob ntawm qee tus neeg cov tshuaj tiv thaiv ntawm lub cev thiab qee yam nuances. Feem ntau, Glucophage kam rau ua tau zoo, kev noj tshuaj siab ntau dhau ntawm cov tshuaj glucose qhov tseem ceeb. Muaj kev yws txog kev txhim kho kev phiv thaum hla lwm ntsiav tshuaj. Cov kev tawm tsam hnyav rau cov tshuaj nquag tsis tshua pom muaj: lactic acidosis tshwm sim.

Glucofage yog ib tus neeg sawv cev antihyperglycemic zoo. Thaum xaiv cov tshuaj zoo tshaj plaws, ua raws cov lus qhia, ntshav qab zib thiab lub cev qhov hnyav yog nyob hauv hom ntshav qab zib hom 2.