Cov tshuaj Baeta muaj qhov ua kom hypoglycemic thiab yog siv thaum kho mob hom 2 mob ntshav qab zib mellitus. Cov cuab yeej no yog ib qho exenatide, uas tau suav hais tias yog amino amino amidopeptide.
Cov tshuaj txhim kho lub tso pa ntawm cov suab thaj txo qis cov tshuaj hormones thiab pab tswj cov glycemia. Nyob rau tib lub sijhawm, nws qeeb qeeb lub khoob ntawm lub plab thiab txhawb txoj haujlwm ntawm beta hlwb ntawm cov txiav.
Kab lus no yuav pab koj nkag siab txog qhov xwm txheej twg koj yuav tsum tau siv tshuaj, thiab nyob rau hauv nws tuaj yeem cuam tshuam tus neeg mob ntshav qab zib.
Cov yam ntxwv dav dav ntawm cov tshuaj
Baeta cov tshuaj yog qhov kev daws tsis tau daws rau subcutaneous Txoj kev lis ntshav. Cov tshuaj ua haujlwm nquag ntawm cov tshuaj yog exenatide, nws kuj muaj me me ntawm sodium acetate trihydrate, metacresol, mannitol, acetic acid, dej distilled. Lawv tso tawm cov tshuaj nyob rau hauv daim ntawv ntawm ampoules (250 mg), txhua tus muaj cwj mem tshwj xeeb nrog lub ntim ntawm 1.2 thiab 2.4 ml.
Cov neeg mob uas tau noj cov tshuaj no tau pom tias yuav txo cov ntshav qab zib vim qhov kev ua no:
- Byeta txhim kho txoj kev tso tawm ntawm insulin los ntawm parenchyma nrog kev nce ntxiv ntawm cov piam thaj hauv cov ntshav ntawm tus neeg.
- Kev siv tshuaj insulin nres nyob rau lub sijhawm thaum muaj txo suab thaj tsawg.
- Cov kauj ruam kawg yog txhawm rau tswj koj cov ntshav piam thaj.
Hauv cov tib neeg kev txom nyem los ntawm kev mob ntshav qab zib thib ob, kev siv tshuaj yaj yeeb ua rau muaj kev hloov pauv:
- Kev tiv thaiv ntawm kev tshaj tawm glucagon ntau lawm, uas tswj cov insulin.
- Kev txwv tsis pub ua kom lub plab zom mov.
- Tsis qab los noj mov.
Thaum cov tshuaj raug tshuaj subcutaneously, cov tshuaj nquag pib ua tam sim ntawd thiab mus txog nws cov txiaj ntsig zoo tshaj plaws tom qab ob teev.
Cov nyhuv ntawm cov tshuaj yog kiag li tso tseg tsuas yog tom qab ib hnub.
Cov lus qhia rau kev siv tshuaj
Tsuas yog tus kws kho mob tau tuaj yeem sau tshuaj, tsis muaj qhov xwm txheej twg koj tus kheej noj tshuaj. Tom qab tau txais Baeta cov tshuaj, cov lus qhia rau kev siv yuav tsum tau ua tib zoo kawm.
Kev qhia tias siv cov tshuaj no yog type 2 mob ntshav qab zib nrog kev kho mono- lossis kho nrog. Nws siv thaum nws tsis yooj yim sua kom muaj kev tswj hwm theem ntawm glycemia. Cov tshuaj tuaj yeem siv ua ke nrog nrog txhais tau tias:
- Metformin;
- Thiazolidinedione;
- sulfonylurea derivatives;
- kev sib xyaw ntawm metformin, sulfonylurea;
- kev sib xyaw ua ke ntawm metformin thiab thiazolidinedione.
Cov tshuaj ntawm cov tshuaj yog 5 μg ob zaug ib hnub rau ib teev ua ntej noj zaub mov tseem ceeb. Nws yog txhaj subcutaneously rau hauv caj npab, ncej puab lossis plab. Tom qab ib hlis uas tau txais kev kho mob zoo, kev noj ntxiv tau nce rau 10 mcg ob zaug ib hnub. Yog tias cov tshuaj siv ua ke nrog sulfonylurea derivatives, qhov koob tshuaj ntawm tom kawg yuav tsum raug txo kom tsis txhob muaj cov neeg mob ntshav qab zib hauv lub xeev.
Cov cai hauv qab no rau kev tswj hwm cov tshuaj yuav tsum tau ua raws:
- nws tsis tuaj yeem raug tswj hwm tom qab noj mov;
- nws yog qhov tsis xav kom txhaj tshuaj intramuscularly lossis intravenously;
- yog tias cov tshuaj tov nrog huab thiab hloov xim, nws yog qhov zoo dua los siv nws;
- yog hais tias cov khoom me me pom hauv kev daws, kev tswj hwm tshuaj yuav tsum tau tso tseg;
- thaum lub sij hawm Bayeta txoj kev kho, kev tsim cov tshuaj tiv thaiv yog ua tau.
Cov tshuaj yuav tsum khaws cia hauv ib qho chaw tiv thaiv los ntawm lub teeb thiab cov menyuam yaus me. Kev ntsuas qhov kub thiab txias yuav tsum pom nyob hauv qhov nruab nrab ntawm 2 txog 8 degrees, yog li nws zoo dua khaws cov tshuaj rau hauv lub tub yees, tab sis tsis txhob khov nws.
Lub txee lub neej ntawm cov khoom yog 2 xyoos, thiab kev daws teeb meem hauv cov xaum xaum yog 1 hli ntawm qhov kub tsis tshaj 25 degrees.
Tus nqi ntawm cov tshuaj thiab tshuaj xyuas
Cov tshuaj Baeta tuaj yeem raug yuav ntawm txhua lub tsev muag tshuaj lossis ua ib qho kev txiav txim hauv lub tsev muag tshuaj online. Nws yuav tsum raug sau tseg tias cov tshuaj tsuas yog muag tshuaj nkaus xwb. Txij li thaum lub chaw tsim khoom ntawm cov khoom no yog Sweden, raws li nws tus nqi yog siab heev.
Yog li, tsis yog txhua tus neeg uas muaj mob ntsuas ntshav qab zib muaj peev xwm them taus mus yuav cov tshuaj no. Tus nqi sib txawv raws li daim ntawv tso tawm cov nyiaj:
- 1.2 ml syringe cwj mem - los ntawm 4246 txog 6398 rubles;
- 2.4 ml koob txhaj tshuaj - los ntawm 5301 txog 8430 rubles.
Tsis ntev los no tau tshawb fawb txog kev lag luam, uas tau kawm los ntawm kev xaiv tus neeg mob uas tau siv cov tshuaj no. Xa mus rau Bayeta cov tshuaj, uas nws tau txheeb xyuas pom tias muaj cov kev mob tshwm sim tsis zoo hauv qab no:
- Kev cuam tshuam ntawm cov hlab ntsha: nkees, cuam tshuam lossis tsis hnov qab.
- Hloov hauv metabolism thiab zaub mov noj: poob phaus, lub cev qhuav dej vim ntuav.
- Ib qho tshwm sim tsis tshua muaj tshwm sim ntawm anaphylactic.
- Kev tsis sib haum xeeb thiab kab mob ntawm lub plab zom mov: nce roj tsim, cem quav, mob nraub qaum (qee zaum).
- Cov kev hloov pauv ntawm qhov tso zis: lub zog ua rau lub raum khiav tsis zoo, nce creatinine ntau ntau, lub raum tsis ua haujlwm lossis nws qhov kev ua tsis zoo.
- Cov tawv nqaij ua xua: alopecia (plaub hau poob), khaus, urticaria, angioedema, maculopapular pob.
Yog lawm, qhov tsis zoo yog qhov siab ntawm tus nqi ntawm cov tshuaj, nws yog vim li no tias ntau tus neeg mob ntshav qab zib tawm lawv cov kev txheeb xyuas hauv Is Taws Nem. Tab sis, txawm hais tias qhov no, cov tshuaj yeej txo cov ntshav siab nyob hauv tus neeg mob cov ntshav thiab pab tua nyhav dhau.
Ntxiv mus, vim yog qhov peculiarities ntawm nws cov nyhuv kho, nws tsis ua rau cov mob ntshav qab zib tsawg.
Cov tshuaj tiv thaiv thiab kev tsis haum
Qee qhov xwm txheej, kev noj tshuaj tsis tuaj yeem ua vim muaj qhov tsis sib haum ntawm tus neeg mob. Nws yuav yog:
- mob ntshav qab zib ketoacidosis - ua txhaum nyob rau hauv cov metabolism ntawm carbohydrates;
- insulin-tso ua hom mob ntshav qab zib;
- lub raum tsis ua haujlwm nrog CC tsawg dua 30 ml / min;
- pathology ntawm lub zom plab tsis muaj gastroparesis;
- kev tsis qaug rau cov tshuaj ntawm cov tshuaj;
- cov menyuam yaus thiab tub ntxhais hluas hnub nyoog qis dua 18 xyoo;
- lub sijhawm uas xeeb menyuam thiab kev pub niam mis.
Nrog kev siv tsis raug lossis rau lwm qhov laj thawj, muaj kev tshwm sim tsis zoo tshwm sim, tshwm sim:
- ua xua, uas yog urticaria, tawv nqaij ua pob, thiab khaus;
- lub plab zom mov - xeev siab, ntuav, pom pob, raws plab, cem quav, txo lub cev hnyav thiab tsis qab los;
- kev cuam tshuam ntawm cov hlab ntsha hauv lub hlwb, namely tsaug zog, kiv taub hau, mob taub hau;
- lub raum / daim siab ua haujlwm;
- nce ntxiv nyob rau lub sijhawm coagulation;
- kev txhim kho ntawm hypoglycemia, pancreatitis, hyperhidrosis;
- kev nce zuj zus hauv cov ntshiab si creatinine.
Thaum muaj mob tshwm sim tsis zoo, tus kws kho mob tshwj xeeb tuaj yeem kho kho txoj kev kho mob nrog cov tshuaj no lossis tso tseg nws siv thoob plaws.
Analogues ntawm cov tshuaj
Hauv rooj plaub thaum tus neeg mob tsis tuaj yeem siv cov kev daws teeb meem no lossis nws xav tias qhov tshwm sim tsis zoo, tus kws kho mob tuaj yeem hloov kho qhov muag ntawm kev kho. Qhov no tshwm sim hauv ob txoj hauv kev - los ntawm kev hloov qhov ntau npaum ntawm cov tshuaj lossis los ntawm tso tseg kiag li. Hauv rooj plaub thib ob, nws yog ib qho tsim nyog yuav tsum xaiv cov tshuaj analog uas yuav muaj tib yam kev kho mob thiab tsis ua mob rau lub cev ntshav qab zib.
Xws li, Baeta tsis muaj cov lus zoo sib xws. Tsuas yog AstraZeneca thiab Bristol-Myers Squibb Co (BMS) cov tuam txhab tsim tawm 100% cov yeeb yaj kiab ntawm cov tshuaj no (cov tshuaj generics). Muaj ob hom tshuaj nyob rau hauv kev lag luam tshuaj Lavxias, uas zoo sib xws hauv lawv cov txiaj ntsig kho kom zoo. Cov no suav nrog:
- Victoza yog ib hom tshuaj uas zoo ib yam li Baeta, yog ib qho tshuaj muaj zog. Cov tshuaj yeeb yaj kiab kuj tseem ua nyob rau hauv daim ntawv ntawm koob txhaj tshuaj tiv thaiv rau subcutaneous infusions hauv ntshav qab zib hom 2. Kev siv cov tshuaj tsis tu ncua yuav pab txo qis qib ntawm glycated hemoglobin rau 1.8% thiab poob qhov ntxiv 4-5 kg thaum lub xyoo ntawm kev kho. Nws yuav tsum raug sau tseg tias tsuas yog tus kws kho mob tuaj yeem txiav txim siab qhov tsim nyog ntawm ib hom tshuaj tshwj xeeb. Tus nqi nruab nrab (2 koob txhaj ntawm 3 ml) yog 10,300 rubles.
- Januvia yog ib qho ua rau kom cov ntshav qab zib tsawg nyob hauv kev kho mob ntshav qab zib hom 2. Muaj nyob hauv ntsiav tshuaj daim ntawv. Tus nqi nruab nrab ntawm cov tshuaj (28 units, 100 mg) yog 1672 rubles, uas yog tus nqi pheej yig ntawm cov tshuaj hauv cov lus nug. Tab sis lo lus nug ntawm yam kev kho mob twg zoo dua rau kev noj qab haus huv tseem nyob hauv kev txawj txaus ntawm kws kho mob.
Thiab yog li, Bayeta tshuaj yog qhov ua kom zoo hypoglycemic tus neeg sawv cev. Nws cov txiaj ntsig kho muaj qee cov yam ntxwv uas pab ua tiav kev tswj glycemic. Txawm li cas los xij, cov tshuaj tsis tuaj yeem siv hauv qee kis, thiab nws kuj tuaj yeem ua rau muaj kev tsis zoo.
Yog li ntawd, kev noj tshuaj rau tus kheej tsis tsim nyog. Nws yog ib qho tsim nyog yuav tsum tau coj mus ncig ua si rau kws kho mob uas tawm tsam qhov kev xav ntawm kev siv tshuaj, suav txog tus yam ntxwv ntawm lub cev ntawm txhua tus neeg mob. Nrog rau txoj kev noj tshuaj zoo thiab ua raws txhua txoj cai rau kev qhia txog kev daws teeb meem, koj tuaj yeem txo cov piam thaj rau theem ib txwm thiab tshem tawm cov tsos mob ntawm hyperglycemia. Daim vis dis aus hauv tsab xov xwm no hais txog tshuaj kho mob ntshav qab zib.
