Nrog rau cov ntshav qab zib tsis yog insulin, ntshav qab zib cov tshuaj txo qis feem ntau siv. Glucophage yog suav hais tias yog ib qho ntawm cov tshuaj nrov tshaj plaws, vim nws ua tau zoo.
Mob ntshav qab zib mellitus, yog ib qho muaj tus kab mob uas haum, thaum xub thawj siab kuj tsis tuaj yeem pom. Thaum lub sijhawm dhau los, qhov qib siab ntawm glycemia ua rau qhov kev yeej ntawm yuav luag txhua qhov nruab nrog. Cov teeb meem txaus ntshai tshaj plaws ntawm ntshav qab zib yog retinopathy, mob ko taw, nephropathy thiab neuropathy.
Txhawm rau tiv thaiv qhov tsis xav ua lub txim, nws yog ib qho tsim nyog yuav tsum ua raws li txhua txoj cai ntawm kev kho mob, suav nrog kev siv cov ntsiav tshuaj Glucofage tsis tu ncua.
Cov ntaub ntawv dav dav txog cov tshuaj
Cov tshuaj no yog qhov ncauj thiab yog nyob rau hauv chav kawm ntawm biguanides, vim tias nws muaj cov khoom tseem ceeb - metformin hydrochloride. Nws yog tsim nyob rau hauv qhov sib txawv, uas yog 500, 850 lossis 1000 mg.
Cov neeg tsim khoom lag luam kuj tsim cov Glucophage Ntev - kev npaj zoo sib xws hauv kev sau, uas muaj cov nyhuv ntev dua. Txawm li cas los xij, hauv tsab xov xwm no peb yuav hais tshwj xeeb txog Kev Ua Nraum Zoo.
Ntxiv nrog rau cov tshuaj nquag, muaj pes tsawg leeg ntawm cov tshuaj tiv thaiv kev tiv thaiv kab mob suav nrog cov khoom xyaw xws li magnesium stearate, povidone thiab opadra huv si.
Nrog rau kev tswj hwm sab hauv ntawm Glucofage, metformin nkag rau txoj hnyuv, ua kom tiav nyob rau hauv nws. Cov ntsiab lus siab tshaj plaws ntawm cov nquag muaj tshwm sim tom qab ob xuaj moos ntawm kev tswj hwm tshuaj. Ua tsaug rau qhov kev txiav txim ntawm cov tshuaj, ib tus tuaj yeem ua tiav cov txiaj ntsig hauv qab no:
- Txo cov piam thaj hauv ntshav mus rau qhov tseem ceeb. Hauv qhov no, lub xeev hypoglycemic tsis pom, txij li thaum cov tshuaj tsis ua rau cov tshuaj insulin ntau lawm.
- Ua kom cov nqaij mos ua rau cov tshuaj hormones tsim tawm.
- Txo cov ntshav qabzib ntau lawm los ntawm kev tiv thaiv glycogenolysis thiab gluconeogenesis.
- Rho lub plab hnyuv nqus ntawm kev nqus ntawm cov piam thaj.
- Txhim kho glycogen synthesis thiab thauj muaj peev xwm ntawm cov kua dej thauj.
- Ua kom ruaj khov thiab txawm tias txo koj lub cev hnyav. Hauv qhov no, muaj kev xyaum coj cov tshuaj no rau cov neeg mob noj qab haus huv uas xav kom poob ceeb thawj. Lawv tsis muaj txo suab thaj hauv qab cov theem ib txwm nyob.
- Txhim kho cov lipid metabolism thiab cov roj cholesterol tsawg.
Cov tshuaj tseem ceeb raug faib ib qho zuj zus hauv txhua cov ntaub so ntswg thiab tsis khi rau cov protein nyob hauv ntshav ntshav. Cov tshuaj tsis tau txhij txhua metabolized, tab sis tawm nrog rau zis.
Tau kawm paub li cas Glucophage ua haujlwm, koj tuaj yeem hais txog cov cim tseem ceeb rau kev siv. Cov no suav nrog cov ntshav qab zib tsis-insulin nrog qhov tsis muaj txiaj ntsig ntawm kev noj haus tshwj xeeb thiab nrog rog rog:
- nyob rau cov menyuam yaus thiab tub ntxhais hluas uas muaj hnub nyoog tshaj 10 xyoo nyob ib leeg lossis siv tshuaj insulin;
- rau cov neeg laus noj nrog ib koob tshuaj lossis nrog lwm cov tshuaj tiv thaiv kab mob ntshav qab zib.
Hauv kev mob ntshav qab zib, thaum muaj lwm cov laj thawj ntxiv rau kev pheej hmoo ntawm kev mob ntshav qab zib hom 2, Glucofage kuj tseem raug kho.
Cov lus qhia rau kev siv tshuaj
Cov kua nplaum nrog tus mob ntshav qab zib hom 2 tau siv soj ntsuam nws qhov ntau npaum li cas thiab txhua cov lus pom zoo ntawm tus kws kho mob mus koom. Thaum muas cov tshuaj, koj yuav tsum paub tseeb tias nws haum thiab paub koj tus kheej nrog cov ntxig. Yog tias koj muaj lus nug ntsig txog kev siv tshuaj, koj tuaj yeem nug cov kws kho mob tshwj xeeb.
Cov paub daws teeb muaj cov ncauj lus nram qab no txog kev noj tshuaj. Thaum pib ntawm kev kho mob, lawv haus ob zaug lossis thib peb 500-850 mg ib hnub thaum lossis tom qab noj mov. Nws yog ib qho tseem ceeb kom faib cov dej haus txhua hnub los ntawm ntau zaus, vim tias qhov kev ua no yuav ua rau lub zog tsis zoo ntawm cov tshuaj. Qhov kev tawm tsam no cuam tshuam nrog kev quav ntawm lub cev rau qhov tshwm sim ntawm metformin. Vim tias qhov no, feem ntau cov neeg mob ntshav qab zib thaum noj Glucofage yws ntawm kem plab, uas yog xeev ntuav, raws plab, ntuav, ib qho xim hlau hauv qhov ncauj ntawm qhov ncauj, mob rau hauv plab lossis flatulence. Dhau li ntawm ob lub limtiam, cov cim zoo li ploj, uas qhia tau tias yuav ua rau kom ntau ntxiv.
Kev saib xyuas txij nkawm yog 1500-2000 mg rau ib hnub. Qhov siab tshaj plaws txhua hnub pub rau haus dej qab zib ntau npaum 3000 mg.
Yog tias tus neeg mob xav tau hloov ntawm lwm cov tshuaj tiv thaiv kab mob rau kev noj tshuaj Glucofage, ua ntej koj yuav tsum tau tsum tsis txhob siv lwm yam tshuaj.
Qee zaum endocrinologist pom zoo kom siv cov tshuaj insulin thiab Glucophage txhaj nrog hom ntshav qab zib hom 2. Ntawm koob tshuaj 500-850 mg ob zaug lossis ib hnub ib zaug, kev noj tshuaj ntawm cov tshuaj insulin yog txiav txim siab coj mus rau hauv tus account cov piam thaj hauv qab.
Muaj pes tsawg lub Ntsiav Tshuaj Glucofage cov menyuam yaus yuav tsum haus? Hauv cov neeg mob hluas, pib txij li 10 xyoo, cov tshuaj tau tso cai siv, ob leeg sib cais thiab sib xyaw nrog insulin. Thawj zaug tshuaj ntau npaum li cas yog 500-850 mg, nyob rau ncua sijhawm nws yuav nce ntxiv rau ob rau peb koob.
Yuav ua li cas haus Glucophage nrog ntshav qab zib? Feem ntau nws tau noj li ntawm 1000-1800 mg rau ib hnub, muab faib ua ob zaug.
Thaum lub raum lub raum lossis cov neeg laus nce ntxiv, Glucophage tshuaj tau noj nyob rau hauv kev saib xyuas tshwj xeeb ntawm tus kws kho mob koom. Txhawm rau ua qhov no, koj yuav tsum kuaj xyuas lub raum ua haujlwm tsawg kawg 2-4 zaug hauv ib xyoos.
Ntim tau khaws cia rau hauv qhov chaw tsaus tsis pub cov menyuam yaus siv. Cov txheej txheem kub yuav tsum tsis pub tshaj 25 degrees Celsius. Raws li txoj cai, txee lub neej ntawm Glucofage 500 lossis 850 mg yog tsib xyoos, thiab Glucofage 1000 mg yog peb xyoos.
Cov tshuaj tiv thaiv thiab ua kom raug mob
Thaum muas Glucophage, cov lus qhia rau kev siv yuav tsum tau kawm.
Daim ntawv foos txuas nrog muaj ib daim ntawv teev npe ntawm cov lus sib dhos rau kev siv cov khoom noj ntawm lub plab.
Ua ntej sau ntawv tawm cov tshuaj tua kab mob tiv thaiv kab mob, tus kws kho mob yuav tsum paub txog txhua tus kab mob ntawm cov ntshav qab zib kom tsis txhob mob hnyav. Yog li, kev siv cov ntsiav tshuaj txwv nrog:
- Xeeb menyuam lossis lub sijhawm pub mis niam.
- Hypersensitivity rau lub ntsiab tivthaiv thiab cov tshuaj ntxiv.
- Mob ntshav qab zib precoma, coma, ketoacidosis, thiab raws li lactic acidosis.
- Lub raum tsis ua haujlwm, lub raum tsis ua haujlwm (creatinine hauv qab 45 ml ib feeb).
- Lub cev qhuav dej ntawm lub cev, cov kab mob sib kis, kev poob siab, uas ua rau muaj kev cuam tshuam ntawm lub raum ua haujlwm.
- Cov kab mob uas ua rau muaj kev pheej hmoo ntawm cov nqaij hypoxia. Cov no suav nrog mob plawv / mob ntsws sai, mob plawv nres, lossis ua pa tsis ua haujlwm.
- Kev tso cai ntawm lub siab lossis daim siab ua haujlwm.
- Kev raug phais mob lossis qhov mob hnyav uas yuav tsum tau siv tshuaj insulin.
- Kev noj zaub mov kom tsawg tsawg thaum noj li ntawm 1000 kcal ib hnub.
- Cawv intoxication los yog kev haus cawv ntev.
- Kev siv ntawm iodine-muaj cov tshuaj tiv thaiv tsis zoo ua ntej thiab tom qab 48 teev ntawm kev kuaj hluav taws xob.
Glucophage yog siv nrog ceeb toom rau cov neeg mob ntshav qab zib, ntau dua 60 xyoo, uas nws txoj haujlwm yog cuam tshuam nrog kev tawm dag zog lub cev, vim lawv nce txoj hauv kev los tsim cov kab mob lactic acidosis. Cov neeg mob raum lub raum tsis ua haujlwm kuj poob rau hauv cov npe no.
Raws li qhov tshwm sim ntawm kev siv tsis raug ntawm cov ntsiav tshuaj lossis rau lwm qhov laj thawj, kev txhim kho kev phiv tshuaj yog tau. Cov lus qhia piav qhia txog cov teebmeem nram qab no:
- mob hauv lub plab zom mov - xeev siab lossis ntuav, saj ntawm hlau, zawv plab, flatulence, mob plab.
- kev cuam tshuam ntawm daim tawv nqaij - ua pob, khaus, khaus.
- cov tsos ntawm megaloblastic anemia.
- cov tsos ntawm lactic acidosis.
- ua txhaum daim siab lossis daim siab mob.
Tsis tas li ntawd, ib qho kev cuam tshuam tshwm sim hauv qhov tshwm sim ntawm kev tsis muaj peev xwm hauv lub cev ntawm cov vitamin B12.
Kev Siv Ceeb Toom Ntau Dhau
Nws yog ib qho tseem ceeb kom paub txog kev haus dej qab zib kom zoo, vim tias nws haus ib ce ntau dhau tuaj yeem coj tsis zoo rau cov ntshav qab zib, qee zaum kuj ua rau neeg tuag taus.
Ntau cov kev tshawb fawb pom tau tias kev siv cov tshuaj metformin ntawm kev noj tshuaj ntau npaum li 85 grams, ntau tshaj qhov tau siv ntau tshaj plaws los ntawm 42,5 zaug, tsis ua rau txo qis glycemia. Tab sis lactic acidosis tej zaum yuav tshwm sim, tab sis dab tsi ua rau tus mob no?
Cov kab mob lactic acidosis, lossis acidosis, yog qhov tshwm sim hnyav ntawm kev ua kom tiav ntawm metformin. Thaum tsis muaj ib qho kev kho tau zoo thiab sai sai, muaj txiaj ntsig tuag tau yog ua tau. Thaum noj Glucofage, ib qho kev siv ntau dhau yog manifested raws li hauv qab no:
- Qaug dab peg nrog kev mob plab tsis haum.
- Asthenia thiab mob plab.
- Acidotic dyspnea.
- Txhawb lub cev kub.
- Qhov kev loj hlob ntawm coma.
Yog tias tus neeg mob tau pom tsawg kawg ib qho ntawm cov kev mob ntawm cov kab mob lactic acidosis, nws yuav tsum raug xa mus rau tsev kho mob tam sim. Tom ntej no, kws kho mob txiav txim siab txog cov ntsiab lus ntawm lactate thiab qhia meej kev kuaj mob. Txhawm rau tshem tawm metformin thiab lactate tawm ntawm lub cev, hemodialysis feem ntau siv. Kuj tseem muaj txoj kev kho kom txo tau cov tsos mob.
Glucophage thiab lwm yam kab mob hypoglycemic
Muaj cov npe teev tseg ntawm cov tshuaj, cov siv nyuaj uas ua rau muaj qhov tsis txaus siab. Qee ntawm lawv tuaj yeem nce qhov hypoglycemic ntawm Glucophage, thaum lwm tus - ntawm qhov tsis tooj, txo nws.
Nws yog nruj me ntsis contraindicated siv cov tshuaj Glucophage thiab xoo hluav taws xob tshuaj. Hauv cov xwm txheej zoo li no, txoj kev pheej hmoo tshwm sim ntawm cov kab mob lactic acidosis nce ntxiv. Yog tias koj yuav tsum siv cov nyiaj zoo li no, koj yuav tsum tsis txhob noj Glucofage ua ntej thiab tom qab 48 teev ntawm kev tshawb fawb siv x-ray.
Qhov ntxim nyiam ntawm acidosis nyob rau hauv cov ntshav qab zib mellitus yog ua tau:
- hauv kev qaug cawv mob hnyav;
- nrog cov khoom noj khoom haus tsis txaus;
- nrog rau cov khoom noj uas tsis muaj calorie tsawg (tsawg dua 1000 kcal hauv ib hnub);
- nrog kev ua txhaum ntawm daim siab.
Cov tshuaj xws li danazol, tshuaj tiv thaiv kab mob siab, tshuaj salicylates, acarbose, insulin txhaj, sulfonylureas, nifedipine nce cov suab thaj-txo cov nyhuv ntawm tus kab mob hypoglycemic.
Txo cov ntshav qabzib-txo cov ntshav ntawm glucophage xws li cov tshuaj xws li hauv zos thiab Gic, chlorpromazine, beta-ob-adrenergic agonists.
Ua ke nrog "voj" diuretics thiab glucophage, nws yog ib qho tsim nyog yuav tsum nco ntsoov qhov kev pheej hmoo ntawm cov kab mob lactic acid tshwm sim los ntawm lub raum tsis ua haujlwm.
Qee cov tshuaj yuav cuam tshuam cov metformin, uas yog nws qhov kev txiav txim siab. Cov no suav nrog cov tshuaj cationic - quinidine, digoxin, amiloride, quinine thiab lwm tus.
Glucophage analogues
Ntau cov tshuaj ntshav qog ntshav pab cov ntshav qab zib thiab nws cov tsos mob tseem ceeb. Yog li, yog tias tam sim ntawd, rau qee qhov laj thawj, kev noj tshuaj Glucophage tsis tau, tus kws kho mob yuav xaiv lwm cov tshuaj uas zoo sib xws hauv lawv cov kev kho kom haum.
Ntawm lawv, cov tshuaj uas muaj tib cov tshuaj nquag muaj qhov sib txawv - txawv txawv. Metformin muaj cov khoom lag luam zoo li Bagomet, Siofor, Gliminfor, Metospanin, Gliformin, Metformin Forte thiab lwm yam.
Siofor, cov piam thaj txo tshuaj uas suav nrog povidone, magnesium stearate, hypromellose, titanium dioxide, thiab polyethylene glycol, tau nrov tshwj xeeb hauv cov khoom lag luam saum toj no. Ua tsaug rau kev siv cov tshuaj Siofor, nws muaj peev xwm ua tiav qhov txo qis hauv cov piam thaj, ib qho kev nce ntxiv ntawm qhov raug mob ntawm cov nqaij ntshiv mus rau cov tshuaj insulin, nrog rau kev poob qis hauv qabzib nqus. Ntawm qhov kev tsis sib haum thiab cov kev coj tsis zoo, Siofor yuav luag zoo tib yam li cov tshuaj hauv nqe lus nug. Lub chaw tsim khoom ntawm Siofor yog lub teb chaws Yelemees, hauv kev sib txuas nrog qhov no nws yog qhov zoo nkauj hloov chaw rau Glucofage.
Cov tshuaj Glucophage thiab analogues muaj nyob - cov neeg sawv cev uas tsis suav nrog metformin hauv lawv cov muaj pes tsawg leeg. Cov no suav nrog:
- Glurenorm yog ib qho tshuaj tiv thaiv kab mob uas muaj glycidone. Ua lub sulfonylurea derivative, Glurenorm qis qis rau cov cell-glucose irritability qhov pib, txhawb kev tsim tawm ntawm cov tshuaj insulin, nce rhiab ntawm cov nqaij mos rau nws, inhibits lipolysis hauv cov roj ntsha rog, thiab kuj txo qhov kev txuam nrog ntawm glucagon.
- Diabetalong yog ib hom tshuaj nrov uas suav nrog gliclazide. Ua tsaug rau qhov kev txiav txim ntawm cov tshuaj, muaj ib txoj cai ntawm kev noj haus metabolism, ua kom lub zog ntawm cov khoom qab zib-txo cov tshuaj hormones, thiab cov nyhuv hemovascular kuj ua tiav.
- Amaril M yog ib hom tshuaj German uas siv rau cov ntshav qab zib tsis yog insulin. Xa mus rau derivatives ntawm peb tiam sulfonylurea. Vim tias cov ntsiab lus ntawm glimepiride nyob rau hauv cov lus muaj pes tsawg leeg, thaum siv Amaril, nws muaj peev xwm ua tiav qhov txo qis ntshav plasma thiab txhawb kev tsim cov tshuaj insulin.
Muaj suav tias yog dab tsi analogues Glucophage muaj, koj tuaj yeem nrhiav kev txheeb xyuas txog Glucophage, nrog rau cov nqi rau cov tshuaj no.
Tus nqi thiab lub tswv yim hais txog cov tshuaj
Hauv cov tsev muag tshuaj, cov tshuaj yuav tau tsuas yog tias muaj ntawv sau los ntawm kws kho mob.
Coob tus neeg mob xaj tshuaj hauv online, vim tias qhov no pab lawv khaws lawv cov nyiaj. Kuj tseem muab sijhawm rau pom cov duab ntawm lub pob thiab nws cov lus piav qhia.
Tsis muaj cov chaw tsim khoom hauv Lavxias ntawm cov khoom no, nws yog tsim los ntawm lub tuam txhab Fabkis kev ua lag luam Merck Sante. Yog li Glucophage raug nqi ntau npaum li cas? Tus nqi ntawm ib tus neeg sawv cev tshuaj tiv thaiv yog nyob ntawm tus naj npawb ntawm cov ntsiav tshuaj thiab qhov ntau npaum li cas:
- 1000 mg (No. 60) - los ntawm 270 txog 346 rubles;
- 850 mg (No. 60) - los ntawm 150 txog 180 rubles;
- 500 mg (No. 60) - los ntawm 183 txog 230 rubles.
Raws li koj tuaj yeem pom, cov tshuaj Glucofage tus nqi yuav siv tau. Hauv Is Taws Nem, koj tuaj yeem pom ntau cov lus zoo hais txog kev siv Glucophage. Piv txwv li, Maria kev tshuaj xyuas (56 xyoo): "Kuv pom Glucofage tau ob xyoos. Lub sijhawm no, cov piam thaj kom rov qab zoo li qub, Kuv paub tseeb tias kuv tau yoo zoo rau kev noj haus thaum noj tshuaj. Kuv tswj tau ob peb phaus ntxiv."
Txog yeeb tshuaj Glucofage tshuaj xyuas yuav tsis zoo. Qhov no yog vim muaj kev mob tshwm sim thaum lub cev yoog raws lub cev mus rau metformin. Hauv qee tus neeg mob, cov nyhuv yog li hais tias lawv tsis haus yam tshuaj no.
Koj tseem tuaj yeem nrhiav kev tshuaj xyuas ntawm cov kws kho mob ntsig txog kev siv tshuaj rau qhov poob phaus. Kev xav ntawm cov kws paub feem ntau hauv qhov no tsis zoo. Lawv pom zoo kom tsis txhob siv cov tshuaj rau lub hom phiaj no.
Glucophage yog cov tshuaj zoo uas ntau tus kws tsim tshuaj txog kabmob endocrinologist qhia kom thiav cov ntshav qab zib hom 2. Yog tias koj tseem tsis tau noj cov tshuaj no, sim Glucofage, thiab yog tias koj twb tau noj nws, haus ntxiv mus. Qhov txiaj ntsig ntawm tus neeg sawv cev tiv thaiv kab mob tsis zoo yog ntau zaus ntau dua li nws qhov tshwm sim tsis zoo.
Cov ntaub ntawv hais txog ntshav qab zib-txo cov tshuaj Glucofage muaj nyob hauv video hauv tsab xov xwm no.
