Vasilip yog yeeb tshuaj uas yog los ntawm pab pawg lipid-txo qis. Lub ntsiab lus tseem ceeb ntawm nws cov kev ua haujlwm yog tias nws yog txhawm rau txhawm rau txo qis hauv lipids (rog) hauv cov ntshav. Vasilip muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj dawb hauv zaj duab xis plhaub, puag ncig, me ntsis convex ntawm ob sab.
Cov khoom siv tseem ceeb ntawm cov tshuaj no tau simvastatin. Nws kuj tseem muaj cov tshuaj ntxiv xws li lactose monohydrate, pregelatinized starch, anhydrous citric acid, vitamin C, hmoov txhuv pob kws, magnesium stearate thiab microcrystalline cellulose. Lub plhaub tshuaj pliav nws tus kheej muaj talc, propylene glycol, hypromellose thiab titanium dioxide.
Qhov ntau npaum ntawm cov tshuaj yog ntawm ob hom - 20 thiab 40 mg txhua.
Tus txheej txheem ntawm kev txiav txim ntawm vasilip
Txij li Vasilip belongs rau lipid-txo tshuaj, nws cov tshuab ntawm kev coj ua yog qhov tsim nyog. Ua ntej tshaj plaws, vasilip txo qhov kev xav ntawm tag nrho cov roj hauv cov ntshav. Muaj ob hom roj (cholesterol) - "tsis zoo" thiab "zoo." Qhov "tsis zoo" ib qho yog lipoproteins uas ntom tsawg, thiab qhov zoo "lipoproteins yog qhov ntau".
Vasilip muaj cov txiaj ntsig rau thawj theem ntawm kev tsim cov roj (cholesterol). Nws suav nrog kev hloov pauv ntawm HMG-CoA (hydroxymethylglutaryl-coenzyme A) rau mevalonic acid. Qhov kev hloov pauv no tshwm sim nyob rau hauv kev tiv thaiv ntawm enzyme HMG-CoAreductase. Vasilip muaj qhov cuam tshuam ntawm qhov enzyme no, vim tias cov roj (cholesterol) tsuas tsis ua. Cov tshuaj kuj cuam tshuam cov roj cholesterol, uas yog twb nyob hauv lub cev. Nws txo cov roj hauv lub cev ua kom cov lipoproteins tsawg ntom, thiab kuj tseem txo qis ntawm triglycerides.
Nws yog cov tshuaj ntawm lipid xwm uas yog lub luag haujlwm rau kev tsim cov atherosclerotic plaques hauv qhov lumen ntawm cov hlab ntsha. Tab sis cov tshuaj tsub kom qhov ntau ntawm cov roj "zoo" cov roj - cuam tshuam nrog lub siab lipoproteins. Qib ntawm apolipoprotein B kuj tseem txo qis - tshwj xeeb cov cab kuj muaj protein ua haujlwm thauj cov roj hauv lub cev.
Ntxiv rau kev txo qis qee qib ntawm lipids, cov khoom xyaw tseem ceeb ntawm Vasilip muaj cov nyhuv ntawm phab ntsa ntawm cov hlab ntsha thiab ntawm cov ntshav nws tus kheej. Ntshav cov ntsiab lus xws li macrophages, uas ua lub luag haujlwm tseem ceeb hauv kev tsim cov roj cholesterol, raug tshem tawm los ntawm kev ua ntawm cov tshuaj, thiab cov plaques lawv tus kheej tau raug rhuav tshem. Tsis tas li, kev sib txuas ntawm cov tshuaj hu ua isoprenoids, uas yog lub luag haujlwm rau kev loj hlob ntawm cov hlwb hauv cov leeg nqaij ntawm cov hlab ntshav, yog qhov tsis tshua pom tshwm sim, vim tias lub nkoj ntsa tsis hnyav, thiab lawv cov lumen tsis nqaim. Thiab ntxiv rau, Vasilip dilates cov hlab ntshav kom zoo thiab txhim kho cov ntshav kev khiav haujlwm.
Qhov loj tshaj tshwm sim yog pom tom qab ib thiab ib nrab lub hlis.
Nta ntawm cov khw muag tshuaj ntawm vasilip
Vasilip yog noj. Nws yog qhov zoo heev nqus tau los ntawm phab ntsa ntawm txoj hnyuv. Qhov siab tshaj plaws ntawm cov tshuaj yog pom ib mus rau ob teev tom qab noj nws, tab sis tom qab 12 teev nws txo mus txog 10%. Cov tshuaj tuaj yeem noj nrog zaub mov, qhov no yuav tsis cuam tshuam nws cov nyhuv. Tsis tas li, nws tsis tuaj yeem ntau hauv lub cev nrog kev siv ntev. Cov tshuaj yog nruj heev khi rau cov ntshav protein, yuav luag 100%.
Vasilip tau hloov pauv mus ua ib qho kev sib xyaw ua ke hauv lub siab. Cov compound no yog hu ua beta hydroxy acid. Nws txoj kev tshem tawm (tshem tawm) yog nqa tawm los ntawm txoj hnyuv loj. Cov tshuaj tawm hauv daim ntawv ntawm metabolites (hloov dua siab tshiab cov khoom).
Ib feem me me ntawm nws tau tawm los ntawm lub raum, tab sis ib qho kev ua tsis muaj zog ntawm cov kab ke tawm los ntawm lub raum.
Kev tshem tawm ib nrab-lub neej - lub sijhawm thaum lub siab ntawm cov tshuaj nyob rau hauv cov ntshav txo qis raws nraim 2 zaug - sib npaug nrog ib teev thiab tsib caug-plaub feeb.
Kev taw qhia thiab contraindications rau siv
Cov kws kho mob feem ntau sau ntawv rau vasilip rau ib qho mob xws li atherosclerosis. Nws lub hom phiaj hauv thawj hypercholesterolemia los yog sib xyaw dyspidemia (qhov ua txhaum ntawm qhov sib txawv ntawm cov ntshav lipids) kuj muaj ntau, ua ke nrog kev ua si lub cev tsis tu ncua, poob phaus, ua raws li kev noj zaub mov tsim, lossis tsis muaj qhov cuam tshuam ntawm lwm yam tshuaj.
Lwm qhov taw qhia yog homozygous cov kab mob hypercholesterolemia. Lawm, nyob rau hauv mus tib seem, kev noj haus thiab kev nqus ntawm lwm cov tshuaj antiatherosclerotic yuav tsum tau ua raws. Vasilip kuj tseem raug kho rau kev tiv thaiv kab mob ntawm cov hlab plawv nrog cov mob atherosclerosis lossis ntshav qab zib, vim tias nws muaj kev pheej hmoo siab los ntawm kev mob plawv, mob ntshav nce hlwb thiab ntau yam vascular pathologies. Thiab tom kawg ib qho tsuas yog ua rau kom cov roj (cholesterol) ntau tuaj thaum tsis muaj kev kuaj mob.
Vasilip yog contraindicated rau tej yam mob xws li:
- mob siab tus mob nyob rau theem mob lossis hom nquag;
- ntev zuj zus hauv daim siab enzymes tsis muaj ib qho tsim teeb meem;
- cev xeeb tub thiab lactation;
- hnub nyoog me;
- kev tsis haum tshuaj rau simvastatin lossis lwm yam tshuaj ntawm cov tshuaj.
Kev saib xyuas tshwj xeeb yuav tsum them rau cov neeg mob uas muaj cov kabmob li hauv qab no lossis qee qhov kev mob tshwj xeeb:
- Nrog rau kev haus cawv ntau dhau.
- Nyob rau hauv muaj cov kab mob cuam tshuam rau daim siab.
- Lub xub ntiag ntawm electrolyte tsis txaus ntseeg nyob rau hauv lub cev.
- Kev ua txhaum loj ntawm cov endocrine system thiab cov metabolism.
- Tsis tu ncua txo lub siab (hypotension).
- Cov hlwv tso quav ntawm lub cev.
- Kab mob ntawm cov leeg mob.
- Kho tsis tau mob qaug dab peg.
- Kev phais mob lossis raug mob hnyav.
- Tsis muaj lactase, ib qho enzyme uas zom lactose (mis qab zib).
- Kev ua txhaum ntawm cov txheej txheem ntawm kev nqus ntawm lactose.
Kev siv tshuaj ib txhij xws li cyclosporine, fenofibrate, amiodarone, verapamil, diltiazem, nicotinic acid, gemfibrozin, nrog rau cov kua txiv kab ntxwv qaub, tseem yuav tsum ceev faj thaum siv vasilip.
Cov lus qhia rau kev siv tshuaj
Ua ntej yuav siv cov tshuaj twg, koj yuav tsum sab laj nrog koj tus kws kho mob txog kev haus dej haus cawv rau koj kom zoo thiab kom paub txog cov lus siv. Kev tswj hwm tus txheej txheem yog yuav tsum noj ib lossis ntau dua ib ntsiav tshuaj ib hnub ib zaug thaum yuav mus pw.
Nws raug nquahu kom noj cov tshuaj thaum hmo ntuj, vim tias thaum tsaus ntuj cov tshuaj tua cov roj (cholesterol) ntau tshaj plaws, tau ua tiav, thiab cov nyhuv ntawm cov tshuaj ua kom tshwm sim ntau dua. Feem ntau pib nrog koob tshuaj 10 mg. Qhov siab tshaj plaws pub siv tau yog 80 mg rau ib hnub. Nws yog tshuaj rau cov neeg mob uas muaj cov kab mob qib siab, nrog rau kev pheej hmoo siab ntawm cov kev mob tshwm sim los ntawm lub siab thiab cov hlab ntsha. Qhov yuav tsum tau txhaj nyob hauv feem ntau yuav tau xaiv hauv ib hlis. Lub sijhawm tiv thaiv ntawm kev kho yog xaiv cais rau txhua tus neeg mob los ntawm nws tus kws kho mob koom.
Nws yuav tsum nco ntsoov tias thaum noj Wazilip, tus neeg mob ib qho zuj zus los ua zaub mov noj, uas nws yuav tsum tau ua raws. Qee qhov, lwm cov tshuaj lipid-txo qis kuj raug kho. Rau cov neeg mob uas muaj kab mob xws li hypercholesterolemia, kev kho mob pib nrog ib koob tshuaj 10 mg, tab sis nws tuaj yeem nce ntxiv txog 40 mg kom tau txais cov txiaj ntsig tshaj tawm. Rau cov kab mob muaj keeb ntawm tus kab mob no, kev tswj hwm ntawm Vazilip tau muab faib ua peb zaug yog tias muaj kev txhaj tshuaj ntau tshaj plaws (80 mg), lossis 40 mg ntawm cov tshuaj yog kws kho ib hnub ua ntej yuav mus pw.
Vasilip muaj cov txiaj ntsig xav tau ob qho tib si hauv kev siv ib qho thiab hauv kev sib xyaw nrog lwm cov tshuaj tiv thaiv kab mob, tshwj xeeb, nrog cov kua tsib acid sequestrants. Cov no yog cov tshuaj xws li colestyramine, colestipol.
Nrog kev siv cov tshuaj cyclosporine, gemfibrozil, nicotinic acid los yog tshuaj los ntawm cov pab pawg ntawm cov fibrates, lawv pib nrog koob tshuaj 5 mg, thiab qhov siab tshaj plaws tau tso cai yog 10 mg. Hauv qhov no, koj yuav tsum tsis pub tshaj qhov koob tshuaj no. Yog tias tus neeg mob noj tshuaj tiv thaiv arrhythmia thiab ntshav siab, xws li Amiodarone thiab Verapamil, ces cov koob tshuaj Vasilip yuav tsum tsis pub ntau tshaj 20 mg rau ib hnub, vim tias lawv tsis sib raug zoo tsis tiav.
Yog tias tus neeg mob hnyav dhau los ntawm kev mob raum tsis ua haujlwm, nyob rau hauv uas txhaws qhov quav tsis tshaj 30 ml / min., Tom qab ntawd Vasilip raug kho nyob rau hauv ib koob tshuaj tsis ntau tshaj 10 mg ib hnub twg. Cov koob tshuaj yuav tsum tau nce siab kom zoo, thiab hauv qhov no tus neeg mob yuav tsum tau soj ntsuam tas li.
Yog tias lub raum tsis ua haujlwm yog tsim, qhov tshuaj tsis hloov. Tib yam mus rau cov neeg laus.
Phiv los sis vasilip thiab noj ntau dhau
Zoo li feem ntau cov tshuaj, Vasilip tuaj yeem ua rau pom qhov tshwm sim ntawm qee qhov kev mob tshwm sim hauv tus neeg mob lub cev.
Kev phiv tshuaj los ntawm kev siv vasilip tsis tshua muaj tshwm sim.
Muaj cov kev mob tshwm sim los ntawm ntau qhov hauv nruab nrog cev.
Lub plab zom mov: kev nyuaj ntawm kev tso quav, mob plab, kev tsim muaj roj ntau dhau, kem plab, xeev siab, qee zaum ntuav, raws plab, hloov pauv ntawm daim siab thiab tus txiav, nce hauv cov kev ntsuas ntawm daim siab enzymes, alkaline phosphatase thiab creatine phosphokinase.
Lub cev tsis muaj zog thiab cov plab hnyuv siab raum: hnov mob taub hau, kiv taub hau, hnov qhov tsis hnov qab, mob neuropathy, teeb meem tsis tsaug zog, pom qhov tsis pom kev, tsis pom kev thiab tsis hnov qab.
Cov leeg mob: myopathies (kab mob ntawm cov leeg ua haujlwm), sib xyaw cov leeg, mob leeg thiab ua kom tawv nqaij.
Kev ua xua tshwm sim: ib daim duab tag nrho ntawm kev paub ntau dhau mus rau yeeb tshuaj, nyob rau hauv uas muaj o, tshwm sim ntawm lupus, cov leeg mob ntev, dermatomyositis, txo qis hauv platelet suav, ib qho kev nce ntawm eosinophils, vasculitis, kev ua kom sai ntawm erythrocyte sedimentation tus nqi, mob thiab cov txheej txheem mob hauv cov pob qij txha, urticaria, nce ntxiv kev hnov mob rau lub teeb, ua npaws, liab ntawm lub ntsej muag, qhov tsis muaj zog dav dav, ua pa nyuaj.
Daim tawv nqaij ua qauv tawv nqaij: tawm pob, khaus khaus, ua pob ntseg sib luag taub hau (alopecia).
Tsis tas li ntawd, tej zaum yuav muaj tsawg dua cov ntshav liab thiab hemoglobin (ntshav liab), lub raum khiav tsis zoo, qis libido, thiab palpitations.
Kev saib xyuas ntau dhau ntawm Vasilip yog pom thaum koob ntawm 3.6 g dhau qhov no. Hauv qhov no, nws yog qhov yuav tsum tau yaug lub plab, siv lub tshuab hluav ncaig lossis laxative kom cov tshuaj seem tsis muaj sijhawm los nqus, thiab cov khoom tuaj sai sai tshem tawm ntawm lub cev. Tus neeg mob yuav tsum tau soj ntsuam tas li.
Muaj cov piv txwv zoo li ntawm Vasilip li Atorvastatin, Krestor, Lovastatin, Rosuvastatin, Akorta. Tag nrho cov ntawm lawv yog nyob rau hauv pawg statins. Cov tshuaj yuav tau ntawm txhua lub tsev muag tshuaj los ntawm cov tshuaj noj. Vasilip yog pheej yig heev - tsis pub dhau 250 rubles. Ua ntej siv nws, nco ntsoov nyeem cov ntawv siv phau ntawv thov.
Tus kws tshaj lij hauv kev yees duab hauv tsab xov xwm no yuav tham txog simvastatin thiab cov tshuaj raws nws.
