Gentamicin yog ib hom tshuaj tua kab mob uas zwm rau pawg aminoglycosides. Nws muaj cov kab mob dav dav.
ATX
J01GB03 - Gentamicin
Gentamicin yog ib hom tshuaj tua kab mob uas zwm rau pawg aminoglycosides. Nws muaj cov kab mob dav dav.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj ua haujlwm nquag yog gentamicin sulfate. Muaj nyob rau hauv daim ntawv ntawm hmoov lossis tshuaj rau hauv kev txhaj tshuaj (hno hauv ampoules), tshuaj pleev thiab tee rau lub qhov muag.
Ntsiav tshuaj
Tsis muaj nyob hauv daim ntawv ncoo.
Ncos
Cov kua ntshiab rau kev siv tshuaj pleev - qhov muag daj. 1 ml muaj 5 mg ntawm lub tshuaj nquag. Ntim hauv 5 ml hauv dropper fwj. Ntim cov ntim khoom ntawm cardboard rau 1 pc. nrog rau cov lus qhia rau siv.
Tshuaj
Cov xim tsis muaj kua ntshiab rau kev txhaj tshuaj (tuaj yeem siv ntshav pleev ib leeg thiab intramuscularly). 1 ml muaj 40 mg ntawm cov tshuaj nquag. Ntim hauv 1 lossis 2 ml hauv khob ampoules. 5 ampoules tau ntim rau hauv pob tawb cov tais, 1 lossis 2 pallets hauv ib daim ntawv cardboard ua ke nrog rab riam ampoule.
Hmoov
Dawb los yog hmoov hmoov, ntim rau hauv 1 kg laminated ntawv ci hnab. 1 g ntawm tshuaj muaj 100 mg ntawm cov tshuaj nquag. Tau teem caij kho tsiaj.
Tshuaj pleev
Rau siv sab nraum zoov. 1 g ntawm cov khoom muaj 0.001 g ntawm cov khoom xyaw dhia. Cov khoom ntim tau ntim rau hauv ntim ntawm 15 thiab 25 g, 1 pc. nrog rau cov lus qhia hauv pob ntawv ntawm cardboard.
Pharmacological kev txiav txim
Cov kab mob tua kab mob. Nws muaj ntau cov teebmeem. Rhiab rau nws:
- aerobic gram-cov kab mob tsis zoo;
- aerobic gram-cov leeg zoo thiab cocci.
Kev nkag mus hauv lub cev, rhuav tshem cov khoom thaiv kev tiv thaiv - cytoplasmic membrane thiab ua rau kev tuag ntawm cov kab mob tuag.
Cov Tshuaj Pharmacokinetics
Nws muaj qhov nqus tsawg tsawg tom qab siv qhov ncauj. Tsuas yog muab rau niam thiab txiv ua haujlwm. Thaum txhaj tshuaj, nws yog kiag li nqus. Qhov siab tshaj plaws hauv cov ntshav ntshav tom qab kev tswj hwm intramuscular yog txiav txim siab tom qab 30-90 feeb, tom qab kev tso ntshav tawm, tom qab 15-30 feeb.
Tsis koom nrog hauv cov txheej txheem hauv metabolism. Lub sijhawm ib nrab tshem tawm yog 2-4 teev. Sau nyob rau hauv qhov chaw lymphatic ntawm lub puab pob ntseg sab hauv thiab lub raum tubules. Nws yog tawm tsuas yog los ntawm lub raum. Nrog lub raum tsis ua haujlwm ntxiv, lub sijhawm ua haujlwm tau txo.
Nws siv rau dab tsi?
Siv rau kev kis mob rau cov neeg laus thiab menyuam yaus los ntawm microflora rhiab. Nws raug pom zoo rau kev kho cov kab mob:
- bronchopulmonary system;
- genitourinary system;
- kev sib xyaw thiab cov ntaub so ntswg mos.
Nws yog siv rau hauv kev kho mob poj niam, nrog mob viav vias thiab hlawv kab mob, otitis media, kab mob plab plab, thiab ntxiv rau kev kho mob kis mob ntawm cov pob txha thiab cov leeg-ligamentous apparatus.
Cov Yuav Tsum Muaj
Nws tsis tau sau tseg yog tias keeb kwm muaj cov ntaub ntawv hais txog cov xwm txheej zoo li no:
- kev tsis qaug rau cov tshuaj ntawm cov tshuaj;
- hnov ntawm cov leeg hlwb;
- lub raum tsis ua hauj lwm.
Siv tsis tau rau lub sijhawm cev xeeb tub thiab lactation. Tsis pom zoo rau cov menyuam mos mus txog 1 hlis.
Nrog saib xyuas
Rau cov neeg mob hnub nyoog (tom qab 60 xyoo), nrog myasthenia gravis, botulism, Parkinson tus kab mob thiab lub cev qhuav dej.
Dosage thiab Administration
Cov qauv tswj rau kev kho mob tsis yooj yim rau cov neeg laus cov neeg mob uas tsis muaj mob rov qab los ntawm lub cev - intramuscularly lossis intravenously, 3 mg ib kg ntawm lub cev txhua 8-12 teev. Kev mob siab rau tshuaj yog muab rau lwm tus mloog li 90-120 feeb (cov tshuaj yog diluted hauv 50-300 ml ntawm sodium tov tshuaj los yog 5% dextrose daws).
Hauv cov qauv mob uas kis tau yooj yim, kev noj tshuaj txhua hnub yog 5 mg rau ib kg ntawm lub cev qhov hnyav, txhua 6-8 teev. Tom qab kev txhim kho, qhov tshuaj tau txo rau 3 mg / kg.
Thaum kis thiab kis kab mob ntawm cov mob txeeb zig, nws yog qhov tau sau ib zaug ntawm 120-160 g rau 7-10 hnub. Rau kev kho mob tus kab mob gonorrhea - ib zaug hauv ib koob ntawm 240-280 mg.
Hauv cov kabmob sib kis hauv cov menyuam mos txij li 1 hlis thiab menyuam txog 2 xyoo - 6 mg / kg thov txhua 8 teev. Cov menyuam yaus txij hnub nyoog 2 xyoos - 3-5 mg / kg peb zaug ib hnub.
Hauv cov kab mob loj, kev txhaj tshuaj yog pom zoo hauv cov tshuaj tsawg dua, tab sis nrog rau kev siv ntau dua.
Rau cov neeg uas lub raum tsis zoo ua haujlwm - hauv kev siv 1-1.7 mg / kg, rau cov menyuam mos - 2-2.5 mg / kg.
Nws puas tuaj yeem noj tshuaj rau ntshav qab zib?
Nrog rau kev tsim muaj tus mob ntshav qab zib taw (kev hem thawj ntawm kev txiav plaub hau), nws tau sau tseg nrog clindamycin.
Sab sij huam
Thaum siv cov tshuaj tua kab mob, qhov tsis txaus ntawm lub cev yog qhov ua tau, ua qauv ntawm:
- xeev siab (txog ntuav);
- Kiv taub hau
- mob taub hau;
- tsaug zog
- psycho-txoj kev xav;
- hnov lus tsis zoo;
- lag ntseg ua tsis tau zoo;
- tsis muaj kev sib koom ua ke;
- hyperbilirubinemia;
- anemia
- leukopenia;
- granulocytopenia;
- thrombocytopenia;
- mob es tsis nco qab;
- lub raum tsis ua haujlwm;
- kev ua xua rau ntawm daim tawv nqaij;
- o tuaj.
Nrog rau siv sijhawm ntev, nws ua rau kev txhim kho superinfection, qhov ncauj thiab mob ntawm qhov ncauj.
Cov lus qhia tshwj xeeb
Thaum mob raws plab heev tshwm sim, nws yuav tsum tau tshem tawm cov kab mob pseudomembranous.
Hauv kev kho cov kab mob sib kis thiab mob ntawm lub genitourinary system, nws yog qhov yuav tsum tau siv ntau ntau ntawm cov dej kom ntau ntxiv.
Txhawm rau tiv thaiv kev txhim kho ntawm lub pob ntseg tsis hnov lus, kev tshawb fawb ntawm cov chaw siab yuav tsum tau nqa tawm tsis tu ncua. Nrog rau cov kev qhia tsis txaus siab, kev siv tshuaj ntawm cov tshuaj tua kab mob yog txo lossis tshem tawm.
Thaum sau tshuaj rau cov neeg muaj hnub nyoog 60 xyoo, tswj hwm ntawm kev tsim cov khoom ntiag tug yog qhov tsim nyog.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Yuav muaj qhov cuam tshuam tsis zoo.
Siv thaum cev xeeb tub thiab lactation
Tsis pom zoo.
Gentamicin rau menyuam yaus
Nws yog siv rau hauv kev kho mob kis mob thiab mob hauv cov menyuam yaus los ntawm 1 hlis.
Siv rau lub sijhawm qub
Nrog ceev faj.
Noj ntau dhau
Kev tswj tsis tau kom tsawg ntawm tus neeg sawv cev tiv thaiv kab mob tuaj yeem ua rau kev txo qis ntawm cov leeg nqaij ntawm cov nqaij kom txog thaum ua pa.
Xav tau tsev kho mob sai.
Kev cuam tshuam nrog lwm yam tshuaj
Koj tsis tuaj yeem nkag ib txhij nrog lwm cov tshuaj (tshwj tsis yog rau isotonic kev daws teebmeem rau kev tswj hwm tus quav).
Txhim kho cov leeg ua kom lub zog ua kom zoo li cov tshuaj curare. Txo cov nyhuv ntawm cov tshuaj tiv thaiv myasthenic.
Nrog rau kev siv tib si nrog diuretics lossis Cisplatin ua rau lawv cov nephrotoxicity.
Ua ke nrog cov tshuaj tua kab mob, cov penicillin series nce lawv cov khoom antimicrobial.
Hauv kev sib xyaw nrog indomethacin ua rau kom muaj kev lom zem ntau ntxiv.
Analogs
Txawm hais tias muaj cov npe loj ntawm cov qauv tshuaj tiv thaiv ntawm cov tshuaj tua kab mob no, lawv tau ua pov thawj lawv tus kheej zoo dua lwm cov tshuaj:
- Garamycin;
- Gentamicin Akos.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Muaj cov tshuaj hauv Latin.
Nqe Gentamicin
Tus nqi nyob ntawm daim ntawv tso tawm tshuaj. Tus nqi qis kawg nkaus hauv cov khw muag tshuaj Lavxias yog los ntawm 35 rubles.
Cia rau cov mob ntawm cov tshuaj Gentamicin
Hauv qhov kub ntau txog + 25˚С. Khaws tsis ncav cuag ntawm cov menyuam yaus.
Hnub tas sij hawm
5 xyoos
Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Gentamicin
Minina T.V., kws kho mob, Novosibirsk.
Aminoglycoside series cov tshuaj tua kab mob nrog ntau yam teebmeem. Nws muaj cov npe loj ntawm cov kev mob tshwm sim. Siv rau kev noj qab haus huv raws li kws kho mob qhia.
Kosyanov E.D., orthopedist, Krasnoyarsk.
Tshuaj tua kab mob muaj zog. Siv los kho kab mob sib kis thiab mob. Orthopedics tau raug kho rau kev kho mob thiab kev tiv thaiv ntawm cov teeb meem sib kis tom qab arthroplasty. Nws muaj contraindications thiab kev txwv rau kev siv. Yuav tsum yog kws kho mob sau.
Marina, 36 xyoo, lub nroog Tomsk.
Kuv tus menyuam muaj mob pob txham nyhav. Tus kws kho qhov muag tau pom zoo siv cov cuab yeej no ua cov kua muag. Siv 1 poob peb zaug ib hnub. Kev txhim kho tau pom tias twb tau ua haujlwm hauv hnub thib 2 ntawm kev kho mob. Tom qab 5 hnub ntawm chav kawm, cov tsos mob tsis zoo lub siab kiag li ploj. Cov cuab yeej siv tsis tau zoo thiab ua tau zoo. Kuv txaus siab rau lub txiaj ntsig.
