Kev siv tshuaj hypoglycemic Glemaz tau sau tseg rau cov neeg mob ntshav qab zib hom 2 ntshav qab zib mellitus thiab zwm rau cov pab pawg ntawm sulfonylurea derivatives ntawm peb tiam. Nws yog siv los tswj cov ntsiab lus ntawm cov piam thaj hauv cov ntshav.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Glimepiride (glimepiride).
Kev siv tshuaj hypoglycemic Glemaz tau sau tseg rau cov neeg mob ntshav qab zib hom 2.
ATX
A10BB12.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj raug muag nyob rau hauv daim ntawv ntawm cov duab sib dhos ua ke ntawm cov duab plaub muaj ib lub duab thiab lub teeb ntsuab hauv cov xim, 4 mg ntawm glimepiride (nquag muaj tshuaj) hauv txhua. Cov khoom siv tsawg: magnesium stearate, daj quinoline zas, xiav pob zeb diamond zas, microcrystalline cellulose, croscarmellose sodium, cellulose.
Hauv cov hlwv ntawm aluminium / PVC 5 lossis 10 ntsiav tshuaj. Hauv pob ntawv tuab ntawm cardboard rau 3 lossis 6 contour blisters.
Pharmacological kev txiav txim
Cov tshuaj yog zwm rau pab pawg ntawm qhov ncauj hypoglycemic. Nws lub cev ua haujlwm txhawb kev ua haujlwm hauv lub hlwb pancreatic, txhim kho cov insulin ntau lawm thiab inhibiting gluconeogenesis. Cov tshuaj muab tshuaj txo cov hyperglycemia yam tsis muaj kev cuam tshuam cov tshuaj lom ntawm cov tshuaj insulin.
Cov txiaj ntsig ua ke ntawm cov tshuaj yog ua raws li kev nce rhiab ntawm peripheral cov nqaij mos ua rau cov kua dej. Hypoglycemic muaj cov tshuaj tiv thaiv antiatherogenic, antiplatelet thiab antioxidant.
Cov Tshuaj Pharmacokinetics
Tom qab noj 4 mg ntawm cov tshuaj, qhov siab tshaj plaws ntawm nws cov tshuaj nquag hauv cov ntshav tau pom tom qab 2.5 teev. Glimepiride muaj 100% bioavailability thaum noj. Khoom noj khoom haus tsis muaj kev cuam tshuam loj heev rau cov tshuaj pharmacokinetic ntawm hypoglycemic.
Li ntawm 60% ntawm cov tshuaj tau tawm los ntawm lub raum.
Li ntawm 60% ntawm cov tshuaj tau tawm los ntawm lub raum, 40% los ntawm txoj hnyuv. Hauv kev tso zis, cov khoom yuav tsis pom nyob hauv daim ntawv tsis hloov pauv. Nws ib nrab-lub neej yog los ntawm 5 txog 8 teev. Thaum noj tshuaj hauv qhov siab kawg hauv cov neeg mob uas muaj lub raum tsis ua haujlwm (nrog creatinine tshem tawm tsawg dua 30 ml / min), muaj qhov nce ntawm kev tshem tawm thiab qhov txo qis hauv plasma concentration thiab cov nyhuv ntawm glimepiride, uas yog los ntawm kev nthuav tawm sai ntawm cov tshuaj vim qhov ua kom tsis muaj zog ntawm nws cov lus cog rau ntshav ntshav.
Kev ntsuas rau siv
Tus neeg sawv cev hypoglycemic yog tshuaj rau cov neeg mob ntshav qab zib hom 2 mob ntshav qab zib mellitus thiab tuaj yeem siv ob qho tib si hauv kev kho mob monotherapy thiab kev sib xyaw nrog metformin thiab insulin kho.
Cov Yuav Tsum Muaj
Hypoglycemic yog contraindicated nyob rau hauv tej yam mob thiab txawv txav:
- ntshav qab zib hom 1;
- leukopenia;
- kev mob raum tsis zoo hauv cov neeg mob uas tau mob hemodialysis;
- mob siab hnyav pathologies;
- thaum muaj hnub nyoog yau;
- pub niam mis thiab noj tus menyuam;
- ketoacidosis uas mob ntshav qab zib thiab mob ntshav qab zib tsis xeev thiab precoma;
- kev ua xua rau cov tshuaj tiv thaiv hypoglycemic.
Cov tshuaj yog ua tib zoo sau tseg rau hauv cov xwm txheej uas yuav tsum hloov chaw ntawm tus neeg mob mus rau kev kho mob insulin (tsis hnov qab cov tshuaj thiab zaub mov hauv lub plab zom mov, kev ua haujlwm hnyav, hlawv thiab mob).
Yuav ua li cas noj Glemaz?
Cov tshuaj siv yog noj ntawm qhov ncauj. Cov koob tshuaj txhua hnub yuav tsum noj thaum lub sijhawm lossis uantej noj mov. Cov ntsiav tshuaj noj tag nrho thiab ntxuav nrog ib nrab khob dej.
Nrog ntshav qab zib
Hauv lub sijhawm thaum ntxov, cov tshuaj yog sau tseg rau hauv koob tshuaj 1/4 ntsiav tshuaj (1 mg ntawm cov tshuaj) 1 zaug / hnub. Thaum tsis muaj qhov zoo ntawm qhov muaj zog, qhov ntau ntxiv yuav nce mus rau 4 mg. Hauv qee qhov tshwj xeeb, nws raug pom zoo tshaj li 4 mg, tab sis ntau dua 8 mg ntawm cov tshuaj txwv ib hnub.
Qhov tuab thiab pes tsawg ntawm cov koob tshuaj hauv ib hnub yog txiav txim siab ntawm tus kheej, suav txog tus neeg mob txoj kev ua neej. Txoj kev kho ntev, nws cuam tshuam nrog kev soj ntsuam ntshav qabzib ntau ntau.
Sab Sij Huam Glemaza
Ntawm ib feem ntawm cov khoom hauv nruab nrog kev pom
Muaj qhov ntxim nyiam ntawm qhov tsis pom kev raug ncua ntev dua nyob rau hauv daim ntawv ntawm ob lub zeem muag thiab qhov tsis meej ntawm kev nkag siab.
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Muaj kev pheej hmoo ntawm cov leeg mob.
Kev kho mob txoj hnyuv
Cov kev phiv tshuaj yog pom los ntawm qhov tsis xis nyob thiab hnyav dua nyob hauv thaj chaw epigastric, ntuav, xeev siab, nce ntxiv hauv cov kev ua ntawm daim siab ua haujlwm siab thiab mob siab.
Hematopoietic plab hnyuv siab raum
Qee qhov xwm txheej, kev txhim kho hemolytic thiab aplastic anemia, agranulocytosis, pancytopenia, erythrocytopenia thiab thrombocytopenia yog sau tseg.
Nruab nrab hauv lub paj hlwb
Muaj qee zaus, muaj kev tsis zoo hauv lub hlwb kev xav, mob taub hau, thiab ua kom lub cev tsis meej pem.
Los ntawm ib sab ntawm cov metabolism
Kev txo qis hypoglycemic tshwm sim sai sai tom qab siv cov tshuaj. Tej zaum lawv yuav loj.
Kev ua xua
Tawm tsam keeb kwm ntawm kev kho mob nrog cov tshuaj, cov neeg mob yuav muaj mob ua urticaria, khaus khaus, khaub thuas sib chwv nrog sulfonamides thiab lwm yam khoom sib xws, nrog rau kev ua xua ntawm vasculitis.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Tau hais tias cov tshuaj tuaj yeem ua rau psychomotor cuam tshuam, nws tau pom zoo kom tsis txhob ua haujlwm ntawm cov txheej txheem nyuaj thaum nws tswj hwm.
Cov lus qhia tshwj xeeb
Qhov tshwm sim ntawm hypoglycemia thaum lub sijhawm siv cov tshuaj hauv cov tshuaj ntawm 1 mg qhia tias glycemia tuaj yeem tswj tau tsuas yog los ntawm kev noj zaub mov noj.
Thaum muaj kev ntxhov siab, yuav tau hloov tus neeg mob mus ib ntus rau kev kho tshuaj insulin.
Nrog cov khoom noj tsis txaus thaum noj tshuaj, qhov kev pheej hmoo ntawm kev muaj ntshav qab zib ntau zuj zus.
Thaum muaj kev ntxhov siab, yuav tau hloov tus neeg mob mus ib ntus rau kev kho tshuaj insulin.
Siv rau lub sijhawm qub
Kev tswj tshuaj hypoglycemic tsis suav nrog kev hloov kho koob tshuaj.
Txiag tej menyuam
Hauv kev ntsuas xyuas ntshav, tus sawv cev hypoglycemic tsis siv.
Siv thaum cev xeeb tub thiab lactation
Thaum cev xeeb tub, nws yog txwv tsis pub siv cov tshuaj hypoglycemic.
Daim ntawv thov rau lub raum khiav tsis zoo
Hauv kev mob hnyav ntawm qhov hloov khoom nruab nrog, cov tshuaj yog contraindicated.
Siv rau lub siab ua haujlwm tsis zoo
Nws yog contraindicated yuav siv cov ntsiav tshuaj rau mob siab daim siab pathologies.
Muaj cov cim qhia tau ntawm hypoglycemia nrog kev noj tshuaj ntau dhau.
Noj tshuaj Glemaza
Tej zaum yuav muaj cov cim qhia ntawm kev kub siab (tawm hws, tachycardia, ntxhov siab, mob plawv, mob taub hau, nce ntau, qab los noj mov, kev nyuaj siab).
Txoj kev kho yog koom nrog kev ntxias ua kom ntuav, ntuav haus ntau ntawm adsorbents thiab haus cawv ntau. Hauv cov xwm txheej loj, ntxiv rau qhov kev daws teeb meem dextrose ntxiv rau yog ua tib zoo saib xyuas cov piam thaj. Ntxiv cov xwm txheej yog tsos mob.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv cov tshuaj ib txhij nrog cov tshuaj hypoglycemic qhov ncauj, anabolics, Metformin, Insulin, Ifosfamide, Fluoxetine thiab ib tug xov tooj ntawm lwm yam tshuaj, ib qho kev nce hauv hypoglycemic kev ua si tuaj yeem pom.
Hauv qab ntawm Reserpine, Guanethidine, Clonidine thiab beta-blockers, qhov qhaj lossis tsis muaj zog ntawm cov tsos mob ntawm tus mob qog ntshav qab zib tau sau tseg.
Cawv tau zoo
Nws yog qhov tsis tsim nyog rau kev sib xyaw nrog cawv vim kev tsis txaus ntseeg ntawm lub cev.
Analogs
Cov tshuaj hypoglycemic tuaj yeem hloov nrog cov tshuaj tiv thaiv zoo thiab pheej yig no:
- Diamerid;
- Glimepiride Canon;
- Glimepiride;
- Amaril.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Koj tuaj yeem yuav hypoglycemic nkaus xwb los ntawm cov tshuaj noj.
Nqi
Txog 30 ntsiav tshuaj koj yuav tsum them tus nqi ntawm 611-750 rubles.
Cia rau cov neeg mob rau cov tshuaj
Ua kom hypoglycemic kom deb ntawm tshav ntuj, av noo thiab chav sov. Blister kev ncaj ncees (tawg) yuav tsum tsis txhob ua txhaum.
Hnub tas sij hawm
24 Hlis.
Chaw tsim tshuaj paus
Tuam txhab "Kimika Montpellier S.A." (Argentina).
Xyuas
Cov kws kho mob
Victor Smolin (kws kho mob), hnub nyoog 41 xyoo, Astrakhan.
Qhov tshuaj hypoglycemic no tsis yog yam tshiab hauv khw lag luam niaj hnub no. Ntawm kev muag koj tuaj yeem nrhiav tsis muaj tsawg dua cov analogues. Txawm li cas los xij, ntau tus kws kho mob nyiam qhov tshuaj no, vim nws cov nyhuv tshuaj tau sim los ntawm lub sijhawm nws tus kheej.
Cov neeg mob
Alisa Tolstyakova, 47 xyoo, Smolensk.
Kuv tau noj cov tshuaj no kom cov ntshav qabzib ntev (ntev li 3 xyoos). Lub sijhawm no tsis muaj kev phiv dab tsi. Kuv tus mob yog qhov xwm txheej zoo, Kuv tsis npaj yuav hloov cov tshuaj ntxiv, thiab tsis muaj qhov xav tau, vim nws cov nqi kiag rau kuv.
Poob phaus
Antonina Voloskova, 39 xyoo, Moscow.
Nrog rau cov tshuaj no, Kuv tau poob phaus me ntsis. Txawm hais tias kuv tsis muaj ntshav qab zib, nws txoj haujlwm tau tso cai rau kuv kom ib txwm muaj cov ntshav qabzib hauv cov ntshav, vim tias kuv tau pib hlawv cov rog rog ntau dua. Tshuaj zoo mob. Kuv yuav ob peb pob nyob rau hauv tseg ib zaug.
