Lysiprex yog cov tshuaj uas npaj rau kev kho mob ntawm cov kab mob ntawm lub plawv thiab leeg ntshav. Muab qhov mob hnyav rau hauv chaw kuaj mob, nws yog siv nrog lwm cov tshuaj los yog khoom siv ywj pheej. Txhawm rau kom cov hlab plawv ua haujlwm nquag rau cov kab mob mus ntev, cov tshuaj tau tawm rau kev tswj hwm prophylactic.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lisiprex.
ATX
S.09.A.A. 03 Lisinopril.
Lysiprex yog cov tshuaj uas npaj rau kev kho mob ntawm cov kab mob ntawm lub plawv thiab leeg ntshav.
Tso cov ntawv thiab cov nyob ua ke
Cov ntsiav tshuaj, cov tshuaj nquag hauv lawv yog 5, 10 thiab 20 mg. Cov duab yog round, tiaj tus. Cov xim yog dawb. Lub ntsiab tseem ceeb: lisinopril, sawv cev hauv kev npaj los ntawm lisinopril dihydrate. Cov tshuaj ntxiv: anhydrous calcium hydrogen phosphate, mannitol, magnesium stearate, pob kws hmoov txhuv.
Pharmacological kev txiav txim
Cov tshuaj muaj nyob hauv pawg ntawm ACE inhibitors. Lisinopril ua rau qeeb ntawm cov kev ua ntawm ACE (angiotensin-hloov enzyme). Vim qhov no, tus nqi ntawm degeneration ntawm angiotensin ntawm thawj hom mus rau hom thib ob, uas muaj cov ntsiab lus vasoconstrictive thiab txhawb kev tsim cov aldosterone los ntawm adrenal cortex, txo qis.
Qhov muab tshuaj txo tus mob hauv cov ntshav me me ntawm lub ntsws, nce qhov tsis kam ntawm lub siab. Nws normalizes glomerular endothelium, lub luag haujlwm ntawm uas raug mob nyob rau hauv cov neeg mob hyperglycemia.
Cov tshuaj nquag nthuav tawm hauv cov hlab ntsa ncig tshaj qhov cuam tshuam rau lub txaj venous. Nrog lub sijhawm siv ntev ntawm cov tshuaj, mob plawv myocardial hypertrophy tsawg dua. Cov cuab yeej tuaj yeem ua kom qeeb ntawm qhov tsis ua haujlwm ntawm lub plawv nres rov qab, txhim kho cov neeg mob uas tau mob plawv.
Cov Tshuaj Pharmacokinetics
Kev noj tshuaj tsis cuam tshuam nrog zaub mov. Qhov txheej txheem nqus mus txog li 30% ntawm cov nquag cov khoom. Bioavailability yog 29%. Kev khi rau cov ntshav muaj ntshav yog qhov tsawg heev. Tsis tas hloov, cov khoom tseem ceeb thiab cov koom haum pabcuam nkag mus rau hauv cov ntshav.
Qhov siab tshaj plaws ntshav plasma yog pom hauv 6 teev. Yuav luag tsis koom nrog hauv cov metabolism. Nws yog tshem tawm tsis hloov pauv ntawm lub raum nrog zis. Ib nrab-lub neej siv sijhawm ntev txog 12,5 teev.
Nws yog dab tsi rau?
Kev taw qhia rau kev siv lysiprex:
- yam tseem ceeb thiab kho dua tshiab hom arterial hypotension;
- mob ntshav qab zib nephropathy;
- mob ntsws raum;
- mob myocardial infarction.
Hauv kev mob plawv hauv lub siab, cov tshuaj yuav tsum noj rau thawj hnub tom qab kev tawm tsam kom tiv thaiv tsis ua haujlwm ntawm cov hlab plawv sab laug.
Cov Yuav Tsum Muaj
Cov chaw khomob hais txog kev tswj Lysiprex:
- ua kom lub cev tsis haum rau qee qhov tshuaj ntawm cov tshuaj;
- muaj cov Quincke edema hauv tsev neeg zaj keeb kwm;
- kev tshuaj ntsuam caj nyiam rau cov tshuaj tiv thaiv xws li mob hlwb.
Tus txheeb ze sib kis, nyob ntawm qhov muaj uas siv ntawm Lysiprex tau tso cai, tab sis ua tib zoo thiab nrog kev soj ntsuam tas li ntawm tus neeg mob, tau txiav txim siab:
- mitral stenosis, aortic, lub raum txhaws;
- mob plawv ischemia;
- kev txhim kho ntawm cov hlab ntsha hypotension;
- mob raum tsis zoo;
- lub xub ntiag ntawm kev nce siab ntawm cov poov tshuaj hauv lub cev;
- kab mob sib kis hauv cov nqaij.
Nws raug txwv tsis pub siv txoj kev kho mob rau hauv kev kho mob plawv hauv cov neeg mob uas yog cov neeg sawv cev ntawm cov haiv neeg dub.
Yuav ua li cas noj lisiprex?
Cov ntsiav tshuaj tau noj tag nrho yam tsis muaj ntxo, tsis hais noj mov. Qhov tshuaj nruab nrab uas pom zoo yog 20 mg rau ib hnub, qhov ntau tshaj plaws tau tso cai txhua hnub yog 40 mg. Lub sijhawm tiv thaiv ntawm kev kho yog suav ib tus zuj zus, nyob ntawm qhov mob hnyav thiab tus mob ntawm cov tsos mob. Kev kho mob zoo li cas ntawm kev noj tshuaj tshwm sim tom qab 14-30 hnub.
Tsuas tshuaj rau monotherapy ntawm mob plawv tsis ua hauj lwm: thawj koob tshuaj - 2.5 mg ib hnub twg. Rau 3-5 hnub, nce ntxiv txog 5-10 mg ib hnub yog ua tau. Tso cai ntau tshaj yog 20 mg.
Kev kho mob tom qab lub plawv nres hauv thawj 24 teev tom qab kev tawm tsam: 5 mg, txhua lwm lwm hnub qhov koob tshuaj yog rov ua dua qhov qub. Tom qab 2 hnub, koj yuav tsum tau noj 10 mg, hnub tom qab, koob tshuaj yuav raug dua nyob rau ntau npaum ntawm 10 mg. Txoj kev kho mob zoo tuaj yeem ntev txog 4 rau 6 lub lis piam.
Mob ntshav qab zib nephropathy - txog 10 mg rau ib hnub, nyob rau hauv cov ntaub ntawv ntawm cov tsos mob mob hnyav, qhov ntau npaum li cas tuaj yeem raug nce ntxiv rau qhov kev tso cai txhua hnub ntawm 20 mg.
Nrog ntshav qab zib
Cov piam thaj hauv qab tsis hloov pauv nyob rau hauv cawv ntawm lisiprex. Kev kho mob ntawm cov neeg mob uas muaj cov tsos mob zoo ib yam tsis tas yuav tsum kho ntau npaum li cas.
Phiv fab ntawm lisiprex
Feem ntau muaj cov kev mob tshwm sim xws li mob taub hau, tsaug zog thiab tsis nco qab, kiv taub hau, mob tachycardia thiab txo qis ntshav siab, kev fab tshuaj rau daim tawv. Lwm cov kev mob tshwm sim tsawg: kev txhim kho myalgia, vasculitis, mob pob txha.
Kev kho mob txoj hnyuv
Mob plab zom mov, txhaws ntswg ua rau xeev ntuav nrog ntuav.
Hematopoietic plab hnyuv siab raum
Kev txo qis hemoglobin concentration, kev txhim kho ntawm agronulocytosis. Tsis tshua muaj txiaj ntsig - qhov nce ntawm ESR uas tsis muaj qhov tshwm sim ntawm cov txheej txheem hauv lub cev.
Nruab nrab hauv lub paj hlwb
Tawm tsam mob taub hau thiab kiv taub hau, mob tsis ua haujlwm.
Los ntawm cov kab mob zis
Cov raum tsis meej, anuria, mob plawv nres.
Los ntawm lub tshuab ua pa
Paroxysmal hnoos tsis muaj hnoos qeev.
Ntawm ib sab ntawm daim tawv nqaij
Urticaria, khaus khaus ntawm daim tawv nqaij. Kev tawm hws ntau dhau, cov tsos ntawm alopecia yog tau.
Los ntawm cov hlab plawv system
Mob nqaij hauv plawv, tsawg dua - arterial hypotension. Tsis tshua muaj - tachycardia, bradycardia, cov tsos mob muaj zog ntau daim duab ntawm lub plawv nres.
Endocrine system
Cov mob uas tsis tshua muaj neeg yog kev ua tsis taus adrenal.
Los ntawm ib sab ntawm cov metabolism
Kev nce siab ntawm creatinine ntau dua. Hauv cov neeg muaj lub raum tsis ua hauj lwm thiab ntshav qab zib pathology, urea nitrogen nce ntxiv.
Kev ua xua
Cov tawv nqaij ua pob ua xua, kev txhim kho tshuaj mob pob khaus.
Nws yog qhov tsis tsim nyog los tswj cov khoom siv nyuaj rau cov neeg uas muaj kiv taub hau thiab mob taub hau thaum noj Lisiprex.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Nws yog qhov tsis tsim nyog los tswj cov cuab yeej nyuaj rau cov neeg uas, nyob rau tom qab ntawm kev noj Lysiprex, muaj qhov tsis zoo ntawm lub hauv nruab nrab hauv lub paj hlwb: kiv taub hau, mob taub hau.
Cov lus qhia tshwj xeeb
Kev noj tshuaj tsis raug muab tshuaj rau cov neeg mob kuaj mob ntsws thiab mob ntsws aortic stenosis. Nws yog txwv tsis pub muab cov tshuaj rau hauv myocardial infarction, yog tias muaj kev pheej hmoo siab ntawm qhov tsis zoo ntawm lub cev.
Ua ntej pib txoj kev kho mob, nws yog ib qhov tsim nyog los kuaj xyuas lub raum. Ceev faj, tsuas yog nyob ntawm qhov muaj qhov taw qhia tshwj xeeb, thaum lwm cov tshuaj tsis tuaj yeem muab cov nyhuv xav tau, qhov tshuaj no tau raug kho rau cov neeg mob raum ua tsis tau ntshav thiab tawv ncauj.
Arterial hypotension tshwm sim hauv cov neeg uas muaj kua dej tsis txaus sai sai los ntawm lub cev vim diuretics, noj zaub mov nrog ntsev tsawg, nquag ntuav thiab zawv plab.
Siv rau lub sijhawm qub
Cov neeg mob uas muaj hnub nyoog tshaj 65 xyoos xav tau kev siv Lysiprex kom zoo, nyob rau hauv muaj cov kab mob ntev, kev noj tshuaj yog xam tus kheej.
Txiag tej menyuam
Cov kev tshawb fawb soj ntsuam rau cov neeg mob hnub nyoog qis dua 18 xyoo tsis tau ua; tsis muaj ntaub ntawv qhia txog kev nyab xeeb ntawm cov tshuaj rau pawg neeg mob no.
Siv thaum cev xeeb tub thiab lactation
Muaj kev pheej hmoo ntawm qhov tsis zoo ntawm tus menyuam, tshwj xeeb tshaj yog nyob rau ntawm ncua sijhawm thib 2 thiab thib peb ntawm tus xeeb ceem. Ib tug poj niam noj Lysiprex ntsiav tshuaj tom qab paub txog cev xeeb tub yuav tsum tsis txhob noj cov tshuaj. Tsis muaj ib qho pov thawj ntawm kev muaj peev xwm ntawm cov tshuaj txuam nrog tshuaj mus rau niam mis. Thaum pub niam mis, noj cov tshuaj no yog txwv nruj me ntsis vim tias muaj kev pheej hmoo tshwm sim tsis zoo rau tus menyuam.
Daim ntawv thov rau lub raum khiav tsis zoo
Txais tau, tab sis cov poov tshuaj concentration yuav tsum tau saib xyuas.
Siv rau lub siab ua haujlwm tsis zoo
Ua tau nrog cov cim tshwj xeeb. Ua ntej thiab thaum kho, nws yog qhov tsim nyog los tsim kev tswj hwm tus mob thiab kev ua haujlwm ntawm lub siab.
Noj ntau tshaj ntawm Lysiprex
Kev noj ntau dhau yuav tshwm sim thaum noj 50 mg lossis siab dua ntawd. Cov tsos mob: tus mob ntshav siab ceev ceev, lub cev qhuav ntawm qhov ncauj, zoo li nkees nkees, nyuaj tso zis thiab tso quav. Cov teeb meem CNS ua tau: ntxhov siab, txob taus.
Kev noj ntau dhau yuav tshwm sim thaum noj 50 mg lossis siab dua ntawd.
Pab: ntxuav lub plab, ua kom pom kev kho mob, noj kab mob thiab mob plab ua kom tsaug zog. Nrog rau qhov nce ntxiv ntawm qhov kev siv ntawm kev coj ntawm cov tsos mob overdose, hemodialysis tau ua tiav.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv ua ke nrog sulfonylureas, muaj kev pheej hmoo siab ntawm lub qog ntshav qab zib.
Cov neeg mob ntshav qab zib pathology raug txwv tsis pub noj tshuaj ib txhij nrog Lovastatin vim tias nws muaj kev pheej hmoo siab heev ntawm kev mob ntshav siab.
Nws yog txwv tsis pub coj Lysiprex nrog cov tshuaj uas muaj cov roj ntsha lithium. Qhov kev sib xyaw ua ke no ua rau muaj kev nce ntxiv ntawm lithium nrog cov tsos mob ntawm intoxication.
Nws yog nruj me ntsis txwv tsis pub ua ke nrog Baclofen, Aliskiren, Estramustine.
Cawv tau zoo
Nws yog txwv tsis pub siv cov khoom uas muaj ethyl thaum kho.
Analogs
Lysiprex hloov: Liten, Lysacard, Dapril, Irumed, Diroton.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Daim ntawv yuav tshuaj.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Tsis suav.
Nqi rau lisiprex
Ntau npaum li cas nyob hauv Lavxias thiab Ukraine tsis paub. Tam sim no cov tshuaj tau tab tom ua pov thawj.
Cia rau cov neeg mob rau cov tshuaj
Ntawm qhov kub thiab txias txog li + 25 ° ะก.
Hnub tas sij hawm
2 xyoos
Chaw tsim tshuaj paus
Irbitsky KhFZ, OJSC, Russia.
Kev txheeb xyuas txog Lysiprex
Angela, 38 xyoo, Moscow: "Txoj kev kawm nrog Lysiprex pab ua rau kuv txiv taw tom qab lub plawv nres. Nws yog ib txoj kev kho mob zoo, nws tsis muaj mob tshwm sim. Nws yog qhov mob siab tias nws tsis tuaj yeem yuav hauv khw muag tshuaj."
Kirill, hnub nyoog 42 xyoos, Kerch: "Kuv tau coj Lysiprex ntsiav tshuaj ntau xyoo rau ntau xyoo. Kuv muaj mob plawv tsis ua haujlwm ntev, ntau cov tshuaj tau sim, tab sis tsuas yog cov tshuaj no qhia qhov tshwm sim zoo tshaj plaws."
Sergey, 45 xyoo, Kiev: "Kuv tau siv cov tshuaj no tom qab mob plawv nres. Nws zoo sai sai, tab sis kuv muaj cov kev mob tshwm sim, kuv lub taub hau mob thiab ntshav siab dhia. Cov tshuaj tsis tau thim vim qhov no, vim nws zoo, thiab mob taub hau yuav thev taus. "
