Mikardis Plus yog hais txog cov tshuaj tiv thaiv qhov ncauj. Cov tshuaj muaj cov tshuaj ua ke ntawm ob lub tebchaw nquag - telmisartan thiab diuretic. Ua tsaug rau qhov kev sib txuam ntawm cov tshuaj no, cov nyhuv ntev ntev yog ua tiav, kav ntev rau 6-12 teev. Kev sib xyaw ntawm hydrochlorothiazide thiab telmisartan tso cai rau koj los ua kom muaj ntshav siab.
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C09DA07.
Mikardis Plus yog hais txog cov tshuaj tiv thaiv qhov ncauj.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, uas muaj 2 lub tebchaw nquag - telmisartan thiab hydrochlorothiazide.
| Kev Sib Txuas Sib Txuas | Siv tau qhov sib xyaw ua ke, mg | ||
| Telmisartan | 80 | 80 | 40 |
| Diuretic | 12,5 | 25 | 12,5 |
| Xim tshuaj ntsuab | Liab sib cuam tshuam nrog paj yeeb | Daj nrog suav cov xim daj | Paj yeeb |
Raws li cov khoom sib ntxiv uas txhim kho qhov nrawm thiab tiav ntawm kev nqus, yog:
- pob kws nplej siab;
- mis nyuj qab zib;
- microcrystalline cellulose;
- sodium hydroxide;
- hlau oxide dyes;
- povidone;
- sorbitol;
- meglumine.
Cov ntsiav tshuaj tau ua cov oval nrog lub ntsej muag biconvex. Tus neeg sawv cev tiv thaiv kab mob tsis tiv thaiv kab mob yog tsis tsim ua hom tshuaj tsuag, tshuaj pleev, lossis kua tshuaj.
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj, uas muaj 2 lub tebchaw nquag - telmisartan thiab hydrochlorothiazide.
Pharmacological kev txiav txim
Telmisartan muaj cov nyhuv antihypertensive vim kev khi rau angiotensin II receptors. Nrog kev tsim ntawm cov txheej txheem zoo li no, cov khoom siv cuam tshuam los cuam tshuam rau kev ua haujlwm ntawm vasoconstrictor enzyme thiab txo qhov kev xav ntawm aldosterone hauv cov ntshav. Angiotensin II tsis tuaj yeem ua kom tawg ntawm bradykinin, vim tias nws yog txhaws los ntawm telmisartan. Yog li no, cov synthesis ntawm bradykinin txuas ntxiv - lub vasodilator nce lumen hauv cov hlab ntshav.
Cov nyhuv vasodilating ua kom zoo dua hydrochlorothiazide vim yog cov nyhuv diuretic. A thiazide diuretic pab txo cov ntshav siab nrog ntshav siab. Nrog rau kev siv ntev, hydrochlorothiazide txo txoj kev pheej hmoo ntawm kev txhim kho cov hlab plawv pathologies thiab kev tuag ntawm cov kab mob no.
Kev kho mob siab tshaj plaws tau tiav nyob rau hauv 3.5-4 teev.
Qhov ntsuas ntshav siab yuav nyob ruaj khov rau 6-12 teev.
Cov Tshuaj Pharmacokinetics
Tom qab siv tas, cov ntsiav tshuaj tau tawg tawm los ntawm txoj hnyuv enzymes.
Thaum tso tawm, cov tshuaj lom neeg hauv cov tshuaj Mikardis Plus tau nrawm rau hauv phab ntsa ntawm cov hnyuv me.
Thaum tso tawm, cov khoom xyaw nquag tau nrawm rau hauv phab ntsa ntawm cov hnyuv thiab nkag rau cov hlab ntshav. Hauv cov txheej txheem hauv cov kab ke, telmisartan thiab hydrochlorothiazide ncav cuag qhov siab tshaj plaws hauv 30-90 feeb. Lub chaw nruab nrog cev ntawm hom mob thib ob ntawm angiotensin receptor antagonist ncav cuag 50%, hydrochlorothiazide li 60%. Cov tshuaj yeeb dej cawv hloov pauv hauv hepatocytes.
Ib nrab-lub neej nyob yog li 6 teev. Telmisartan tawm hauv lub cev rau hauv daim ntawv ntawm cov khoom siv ua tsis zoo los ntawm cov kab mob tso zis rau ntawm 60-70%. Hydrochlorothiazide yog pom tsis hloov pauv hauv cov zis ntawm 95%.
Kev ntsuas rau siv
Cov tshuaj yog tsim nyog los txo cov ntshav siab nrog qhov tsis muaj txiaj ntsig ntawm kev kho mob telmirsartan li monotherapy.
Cov Yuav Tsum Muaj
Cov tshuaj tsis yog npaj rau kev kho mob ntawm tus neeg mob nrog tus neeg tsis kam mus rau kev ua haujlwm thiab ntxiv ntawm Mikardis Plus. Cov txheej txheem hauv qab no tseem ua haujlwm sib kis rau kev siv:
- bile leeg tav kev tav nrog cov cholestasis concomitant;
- lub siab ua haujlwm tsis zoo;
- ntaus cim txo hauv raum muaj nuj nqi;
- mob ntshav qab zib hnyav mellitus;
- kom muaj cov calcium ntau ntxiv thiab cov poov tshuaj tsawg nyob hauv lub cev;
- cov kab mob tsis sib haum ntawm intolerance rau galactose, fructose, lactose.
Cov tshuaj yog txwv rau kev siv rau cov neeg mob lub raum tsis ua haujlwm thiab ntshav qab zib nrog kev siv Aliskiren thaum uas tig mus.
Yuav noj li cas
Nrog qhov mob me mus txog qhov kawm ntawm pathology, Mikardis noj 1 zaug nyob rau ib hnub, yam tsis tas yuav zom. Kev nkag noj cov zaub mov kom tsawg tsis cuam tshuam rau pharmacokinetics ntawm Mikardis.
Nrog qhov mob me mus txog qhov kawm ntawm pathology, Mikardis noj 1 zaug nyob rau ib hnub, yam tsis tas yuav zom.
Rau cov laus
Kev noj tshuaj txhua hnub muab rau ib koob tshuaj ib ntsiav tshuaj muaj 80 mg ntawm telmisartan thiab 12.5 mg ntawm hydrochlorothiazide. Yog tias cov nyhuv hypotensive tsis txaus, tab sis nrog kev thev taus zoo, koj yuav tsum haus cov ntsiav tshuaj uas muaj 80 mg ntawm telmisartan thiab 25 mg ntawm hydrochlorothiazide.
Qhov siab tshaj plaws hypotensive nyhuv yog pom 1-2 lub hlis tom qab pib ntawm kev txuag kho.
Cov neeg mob uas mob ntshav siab yuav tsum noj 2 ntsiav tshuaj ib hnub. Hauv qhov no, ntau npaum li cas ntawm hydrochlorothiazide yog kho los ntawm tus kws kho mob mus kawm nyob ntawm seb cov ntaub ntawv soj ntsuam ntawm tus neeg mob.
Sijhawm Mikardis Plus rau menyuam yaus
Cov tshuaj yog contraindicated rau kev siv kom txog thaum muaj hnub nyoog 18 vim tsis muaj cov ntaub ntawv ntawm cov nyhuv ntawm cov tshuaj yeeb dej caw rau tib neeg kev txhim kho hauv preschool thiab thaum tiav hluas.
Cov tshuaj Mikardis Plus yog contraindicated rau kev siv txog 18 xyoo.
Noj cov tshuaj rau ntshav qab zib
Cov neeg mob ntshav qab zib yuav tsum kuaj xyuas lawv cov ntshav cov ntshav qabzib tas li. Thaum kho nrog Mikardis, muaj kev pheej hmoo ntawm hypoglycemia vim yog cov nyhuv diuretic ntawm hydrochlorothiazide.
Sab sij huam
Cov kev xav tsis zoo muaj qhov cuam tshuam vim kev xaiv tsis raug thiab ntau tus yam ntxwv muaj feem cuam tshuam txog qhov tsis txaus siab.
Kev kho mob txoj hnyuv
Muaj kev pheej hmoo ntawm kev tsim muaj ulcerative erosive qhov txhab ntawm lub plab thiab lub plab zom mov. Qee tus neeg mob hnov mob mob epigastric, cem quav, raws plab, thiab xeev siab.
Hematopoietic plab hnyuv siab raum
Qib uas tsim muaj hauv cov ntshav ntshav txo qis.
Nruab nrab hauv lub paj hlwb
Nrog kev nyuaj siab ntawm lub hauv nruab nrab lub paj hlwb thiab kev loj hlob ntawm lub hlwb kev xav ntawm ib tug neeg, tus cwj pwm tus qauv hloov - lub xeev muaj kev ntxhov siab, lub siab ntxhov siab tshwm sim.
Kiv taub hau, mob taub hau, plhws, qhov tsis muaj zog ntau, pw tsaug zog yuav tshwm sim.
Los ntawm cov kab mob zis
Hauv cov neeg mob uas tsis muaj teeb meem cov zis tawm (nrog benign prostatic hyperplasia, prostatitis), tso zis cia, zais zis tsis tuaj yeem ua tau. Tsis tshua muaj, muaj kev nce siab hauv cov ntshav plasma concentration ntawm uric acid.
Los ntawm lub tshuab ua pa
Tawm tsam keeb kwm ntawm angioedema, cov tsos ntawm cov hlab pas thaiv, cov tsos mob ntawm tus mob bronchospasm yog tau.
Los ntawm cov leeg musculoskeletal
Cov kev xav tsis zoo nyob rau hauv cov leeg leeg txheej txheem yog qhov txawv txav ntawm cov leeg hauv plab plab hlaub, mob hauv cov pob qij txha thiab cov leeg, tshwj xeeb yog sab nraub qaum.
Kev ua xua
Hauv kev xyaum ua haujlwm tom qab muag tag, kis ntawm cov tsos mob ntawm cov kab mob lupus erythematosus, angioedema, thiab tawv nqaij raug kaw.
Cov lus qhia tshwj xeeb
Cov tshuaj muaj cov nyhuv vasodilating pheej. Nrog rau qhov qis ntawm cov ntshav ncig (BCC), lub siab nyob rau hauv cov hlab ntshav yuav txo qis, vim tias cov kua dej thiab ntshav ntim yuav tsis txaus rau kev ncig mus los. Vim tias tseem muaj cov tsos mob hypotension tsim txom, cov neeg mob noj zaub mov kom tsis muaj ntsev ntau, nrog raws plab thiab ntuav, thaum noj cov tshuaj diuretics ua ntej noj Mikardis Plus, nws yog qhov yuav tsum tau rov qab los ntawm BCC.
Hauv qee kis, cov tshuaj ua rau cov tawv nqaij ua xua.
Noj tus neeg sawv cev hypotensive tuaj yeem ua rau txhim kho cerebrovascular kev raug mob lossis lub plawv nres hauv cov neeg mob mob plawv ischemia.
Hydrochlorothiazide muaj peev xwm ua rau muaj kev hnoos qeev ntawm myopathy lossis qhov tshwm sim ntawm lub kaum ntse ntse lub ntsej muag. Thawj cov tsos mob ntawm tus txheej txheem pathological yog qhov mob siab rau lub qhov muag, uas tsis ploj mus ntev. Yog tias koj hnov mob thiab nrog qhov txo qis hauv qhov muag pom, koj yuav tsum nres tam sim ntawd noj Mikardis Plus.
Cawv tau zoo
Hauv lub sijhawm tiv thaiv kabmob ntshav, nws tsis pom zoo kom haus dej cawv.
Kev haus dej cawv ethyl tuaj yeem txo cov nyhuv antihypertensive, txhim kho cov diuretic nyhuv ntawm hydrochlorothiazide thiab ua rau spasm ntawm cov leeg endothelium nyob rau hauv cov hlab ntsha peripheral.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tsis cuam tshuam rau kev ua haujlwm ntawm lub leeg tsis muaj zog thiab cov txuj ci zoo ntawm lub cev. Hauv qhov no, koj yuav tsum soj ntsuam kev tiv thaiv kev nyab xeeb thaum ua haujlwm nrog cov txheej txheem tsis yooj yim thiab thaum tsav tsheb, vim tias nws muaj peev xwm ua rau tsis nco qab, qhov tshwm sim ntawm kev mob tshwm sim (tsaug zog, kiv taub hau). Cov kev xav tsis zoo tuaj yeem ua rau txo qis ntawm kev saib xyuas thiab qhov ceev ntawm lub hlwb kev xav uas tsim nyog rau kev tsav tsheb.
Siv thaum cev xeeb tub thiab lactation
Cov poj niam thaum cev xeeb tub raug txwv tsis pub noj Mikardis vim qhov muaj peev xwm ua rau muaj kev xeeb menyuam.
Hauv cov txheej txheem ntawm embryonic txoj kev loj hlob, kev tso ntawm cov hlab plawv thiab cov leeg yuav tuaj yeem ua puas lawm.
Thaum mus kho kev siv tshuaj, nws yog ib qho tsim nyog yuav tsum tsis txhob pub mis niam.
Thaum mus kho kev siv tshuaj, Mikardis Plus yuav tsum tsum tsis txhob pub mis niam.
Noj ntau dhau
Nrog rau ib qho koob tshuaj ntau ntawm qhov siab kawg siab tshaj qhov pom zoo pom zoo, qhov kev pheej hmoo ntawm cov cim qhia kev noj ntau dua nce. Cov tsos mob muaj xws li:
- txo qis ntshav siab;
- nce lossis txo lub plawv dhia;
- xeev siab
- tsis meej pem txog txoj kev nco qab;
- tsaug zog
Hauv qee kis, cov nyhuv tshuaj diuretic muaj zog. Vim tias qhov poob ntawm qhov ntau ntawm cov kua dej, lub cev yauv ua kom lub cev qhuav dej, thiab cov theem hauv electrolytes tsawg dua. Qhov tshwm sim ntawm cov ntshav qog ua rau mob nqaij ntswj lossis ua rau lub cev tsis tuaj yeem.
Nyob rau hauv cov ntaub ntawv ntawm overdose, tus neeg mob yuav tsum tau pw hauv tsev kho mob. Nyob rau hauv chaw puag, kev kho yog tsom mus rau tshem tawm cov tsos mob tsis zoo thiab ua kom muaj dej-electrolyte sib npaug.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv ua ke nrog Mikardis nrog cov roj ntsha uas muaj cov roj ntsha lithium, qhov kev hloov pauv ntawm cov dej ntshiab lithium yog qhov ua tau.
Hauv qhov no, lub raum tshem tawm ntawm cov roj ntsha lithium tsawg zuj zus thiab qaug cawv kev loj hlob, uas yog vim li cas nws tsis pom zoo kom sau cov tshuaj kho mob sib piv nrog cov roj ntsha lithium thiab ib qho tshuaj tiv thaiv kab mob siab. Ib qhov xwm txheej zoo sib xws yog pom nrog poov tshuaj npaj.
Cov tshuaj noj uas txo cov poov tshuaj ntsiab lus hauv cov ntshav ntshav pab txhawb kev txhim kho hypokalemia. Nrog rau lawv txoj kev tswj hwm ib txhij nrog Mikardis, nws yog qhov tsim nyog los tswj theem ntawm cov poov tshuaj hauv lub cev.
Cov tshuaj nonsteroidal anti-inflammatory (NSAIDs) tuaj yeem ua rau lub cev qhuav dej, uas yog vim li cas cov neeg laus dua 50 xyoo muaj feem ua kom lub raum tsis ua haujlwm. NSAIDs txo cov kev kho mob ntawm diuretics thiab cov tshuaj tiv thaiv kabmob ntshav.
Anticholinergic cov tshuaj ua ke nrog Mikardis Plus txo qhov kom zoo ntawm cov leeg ntawm cov hnyuv plab.
Derivatives ntawm barbituric acid thiab antipsychotics provoke kev txhim kho orthostatic hypotension nrog tom qab tsis nco qab.
Metformin tsub kom muaj kev pheej hmoo ntawm cov kab mob lactic acidosis thaum sib tham nrog hydrochlorothiazide.
Lwm cov tshuaj tiv thaiv kev tiv thaiv ua ke nrog Mikardis yog synergistic - qhov kev tiv thaiv hypotensive yog ua kom zoo dua ob peb zaug nyob ntawm seb tus neeg yam ntxwv ntawm tus neeg mob.
Cov roj khov ua cov roj qeeb ua kom qhov nqus nqus ntawm hydrochlorothiazide. Cov tshuaj Anticholinergic nce cov bioavailability ntawm thiazide diuretics, vim tias muaj qhov txo qis ntawm peristalsis ntawm cov leeg nqaij ntawm cov hnyuv plab.
Chaw tsim tshuaj paus
Beringer Ingelheim Ellas A.E., Koropi, Tim Nkij teb chaws.
Mikardis Ntxiv Lus Tshaj Qhia
Thaum tsis muaj cov nyhuv hypotensive, Mikardis tuaj yeem hloov nrog ib qho ntawm cov analogues:
- Cov Noo;
- Tshuab luam ntawv;
- Lozap Ntxiv;
- Telmisartan;
- Telmisartan Richter;
- Telmista.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj tuaj yeem tau yuav ncaj qha los ntawm kev siv tshuaj.
Nqi
Tus nqi nruab nrab ntawm cov ntsiav tshuaj sib txawv ntawm 1074 txog 1100 rubles.
Mikardis Plus cia rau cov neeg mob
Nws raug nquahu tias tus neeg sawv cev antihypertensive muab khaws cia rau hauv qhov chaw sib cais los ntawm ultraviolet hluav taws xob ntawm qhov kub ntawm + 8 ... + 25 ° C.
Hnub tas sij hawm
3 xyoos
Kev txheeb xyuas txog Mikardis Plus
Raws li cov kws kho plawv thiab cov neeg mob, Mikardis yog qhov muaj txiaj ntsig zoo hauv kev tiv thaiv tiv thaiv kub siab.
Kev kho plawv
Elena Bolshakova, kws kho plawv, Moscow
Kuv tau ua ib qho kev tshawb fawb ua ib feem ntawm kev tawm tswv yim rau cov teebmeem ntawm cov tshuaj, yog li kuv tuaj yeem ntseeg siab tham txog cov hauj lwm zoo ntawm Mikardis. Cov tshuaj pab ua kom lub hauv nruab nrab ntawm lub siab qhov tseem ceeb thiab txo qis kev tshaj tawm ntawm lub plawv, uas ua rau muaj kev loj hlob ntawm cov kab mob plawv. Cov tshuaj muaj txiaj ntsig zoo rau ob leeg rau cov hluas thiab rau cov laus. Cov kev mob tshwm sim uas yuav xav tau cov kev kho mob hloov, hauv kev coj ua tsis tau ua tiav. Cov tshuaj tsis cuam tshuam rau lub siab.
Sergey Mukhin, kws kho plawv, Tomsk
Kuv xav tias cov tshuaj yog txiaj ntsig zoo txo qis ntshav siab. Thaum noj ib hnub ib zaug, cov nyhuv tshuaj ua mob ntev li ib hnub. Tus nqi yog siab. Ib daim ntawv loj loj ntawm contraindications. Tab sis cov tshuaj muaj txiaj ntsig zoo rau yam 2 mob ntshav qab zib, mob plawv ruaj khov. Nws raug txwv tsis pub siv rau hauv cov neeg mob nrog mob plawv tsis zoo. Kev tsis haum qhov tsis tshua pom tshwm sim hauv kuv txoj kev kho mob.
Mikardis Plus tuaj yeem hloov nrog Pritor, uas tau muab tso rau hauv ib qho chaw sib cais los ntawm kev siv duab ci ntsa iab ntawm qhov kub ntawm + 8 ... + 25 ° C.
Cov neeg mob
Dmitry Gavriilov, 27 xyoo, Vladivostok
Arterial hypertension pib, vim tias nyob rau yav tsaus ntuj muaj kev noj qab haus huv tsis zoo, qhov tsis tu ncua ntawm huab cua, thiab arrhythmia tsim. Cov kws kho mob sau ntawv yuav Mikardis ntsiav tshuaj. Cov tshuaj pib ua rau thawj hnub. 3 teev tom qab noj cov ntsiav tshuaj, lub siab ruaj khov rau 20 teev ntxiv. Nws yog ib qho tseem ceeb rau noj lwm yam tshuaj uas yuav pab tswj tau qhov tshwm sim no. Kuv pom zoo kom sab laj nrog koj tus kws kho mob txog kev kho cov khoom noj ua ke nrog cov vitamin ua ntau ntxiv.
Alexandra Matveeva, 45 xyoo, St. Petersburg
Ntsib nrog kub siab tom qab phais mob ntawm cov thyroid caj pas. Tus kws kho plawv tawm tshuaj MikardisPlus cov ntsiav tshuaj ntawm lub sijhawm ntev. Kuv nyiam cov tshuaj, nws maj mam ua kom ntshav siab. Qhov tshwm sim ntawm cov tshuaj tsis cuam tshuam rau lub cev thiab tsis ua rau muaj kev tsis zoo, phiv tshuaj tiv thaiv. Lub siab tau mus txog 130/80 thiab tseem nyob qib no. Kuv qhia koj kom mus so ntawm 2 lub lis piam thaum noj tshuaj.
