Irumed yog ib qho yeeb tshuaj hypotensive siv rau hauv kev kho kab mob siab thiab lwm yam kab mob ntawm lub plawv thiab cov hlab ntsha cuam tshuam nrog nce siab hauv cov hlab ntsha. Yog tias siv tsis raug, nws tuaj yeem ua rau muaj kev phom sij txog lub neej, yog li koj tuaj yeem pib noj cov tshuaj tsuas yog kev tso cai los ntawm tus kws kho mob.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lisinopril - lub npe ntawm cov tshuaj nquag ntawm cov tshuaj.
Irumed yog ib qho yeeb tshuaj hypotensive siv rau hauv kev kho kab mob ntshav siab thiab lwm yam kab mob pathologies ntawm lub plawv thiab cov hlab ntshav.
ATX
С09АА03 - cai rau kev tso tawm tswv yim-tshuaj - tshuaj lom neeg sib txawv.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj cov ntsiav tshuaj daim ntawv tso tawm. Cov qov ntawm cov ntsiav tshuaj suav nrog:
- lisinopril dihydrate (10 lossis 20 mg);
- mannitol;
- qos yaj ywm hmoov txhuv nplej siab;
- calcium phosphate dihydrate;
- hlau oxide daj;
- silicon dioxide anhydrous;
- qos yaj ywm hmoov txhuv nplej siab pregelatinized;
- magnesium stearate.
Cov ntsiav tshuaj muab nkag rau hauv 30-cell polymeric hlwb, uas tau muab tso rau hauv cov thawv ntawv los ua ke nrog cov lus qhia.
Pharmacological kev txiav txim
Lisinopril yog ACE inhibitor uas muaj cov khoom hauv qab no:
- nce tus naj npawb ntawm sab hauv vasodilator prostaglandins;
- Kev ua kom tsis tshua muaj tshuaj lom neeg lub cev thaum cov tshuaj tiv thaiv kab mob angiotensin hloov dua siab tshiab rau hom 2 angiotensin, uas ua rau muaj ntshav nce siab;
- txo cov vasopressin thiab endothelin, uas muaj vasoconstrictor yam ntxwv;
- txo cov capillary tsis kam thiab leeg ntshav siab;
- normalizes contractile kev ua ub no ntawm lub plawv dhia, nce qhov ua siab ntev ntawm lub siab mus rau kev ntxhov siab hauv cov neeg muaj lub plawv tsis ua haujlwm;
- Nws muaj cov lus tshaj tawm hypotensive, uas kav tsawg kawg ib hnub;
- inhibits cov kev ua ntawm renin-angiotensin system ntawm myocardium, txwv tsis pub cov tuab ntawm cov leeg nqaij thiab qhov nthuav tawm ntawm cov leeg seem;
- txo qhov siab nyob rau hauv cov hlab ntsws;
- txo cov naj npawb ntawm kev tuag ntawm cov neeg mob uas tau myocardial infarction, mob siab rau cov ntshav ntws hauv cov hlab ntsha loj lossis mob plawv.
Irumed normalizes contractile kev ua si ntawm cov leeg plawv.
Cov Tshuaj Pharmacokinetics
Thaum siv cov ntsiav tshuaj daim ntawv ntawm Irumed, cov tshuaj nquag ua sai sai rau hauv lub cev. Noj mov tsis hloov pauv qhov tsis haum pharmacokinetic ntawm lisinopril. Qhov ntau tshaj plaws ntawm cov khoom hauv cov ntshav tau txiav txim siab tom qab 6 teev. Lisinopril tsis cuam tshuam nrog cov plasma cov Cheebtsam thiab tsis yog metabolized. Cov tshuaj nrog zis tsis hloov pauv. Ib nrab ntawm cov tshuaj tau tawm hauv lub cev tsis pub dhau 12 teev.
Dab tsi yog xaj tshuaj
Cov lus qhia rau kev teem caij ntawm Irumed yog:
- kub siab (raws li tsuas yog kho tus neeg sawv cev lossis hauv kev sib xyaw nrog lwm cov tshuaj);
- mob plawv tsis ua hauj lwm (ua ke nrog diuretics lossis plauv plawv glycosides);
- kev tiv thaiv thiab kho myocardial infarction (nyob rau thawj hnub, cov tshuaj tau raug tswj los tswj cov kab mob hemodynamic thiab tiv thaiv kev mob plawv);
- kev mob ntshav qab zib rau lub raum (kom txo qis ntawm cov tshuaj albumin tawm hauv cov zis hauv cov neeg muaj ntshav qab zib hom 1 thiab ntshav qab zib hom 2).
Cov Yuav Tsum Muaj
Cov tshuaj tsis tau sau tseg rau:
- kev tsis haum tshuaj rau lisinopril thiab lwm yam ACE inhibitors;
- yav dhau los Quincke's edema ntxias los ntawm kev noj tshuaj antihypertensive;
- caj ces mob hlwb;
- kev tswj hwm ib txhij hauv cov tshuaj raws li aliskiren.
Nrog saib xyuas
Cov tshuaj tiv thaiv sib kis rau kev siv cov tshuaj tiv thaiv kabmob ntshav yog:
- hais tau nqaim ntawm lub raum;
- hloov raum tsis ntev los no;
- txhawb theem nitrogen thiab potassium hauv cov ntshav;
- mob ntshav hlab ntsha;
- obstructive cardiomyopathy;
- arterial hypotension;
- kev ncig mus los hauv lub hlwb;
- tus cwj nrag;
- ischemic kev puas tsuaj rau cov leeg plawv;
- decompensated mob plawv tsis ua hauj lwm;
- cov qhov txhab mob sib txuas hauv lub cev;
- mas ua raws li qhov kom ua ntsev kom txhob haum;
- lub cev qhuav dej;
- cuam tshuam ntawm cov kab mob hematopoietic;
- ua rau hemodialysis;
- npaj lossis ncua sijhawm kev phais mob.
Yuav ua li cas coj Irumed
Cov ntsiav tshuaj tau siv 1 zaug nyob rau ib hnub, saib xyuas cov txheej txheem ntawm kev txais neeg kawm. Cov koob tshuaj nyob ntawm hom kab mob pathology:
- Arterial hypertension - hauv thawj lub lis piam ntawm kev kho mob noj 10 mg ib hnub twg. Txij li 3 lub lis piam, cov tshuaj tau pib nce zuj zus mus rau ib qho kev saib xyuas txij nkawm (20 mg). Nws yuav siv sijhawm tsawg kawg ib hlis los tsim kev mob hypotensive. Yog tias tom qab lub sijhawm no pom qhov tshwm sim tsis zoo, cov tshuaj yuav tsum tau hloov.
- Renovascular tawg - pib kho nrog 2.5-5 mg ib hnub. Txoj kev kho yog suav nrog kev saib xyuas lub raum.
- Lub plawv tsis ua haujlwm - ua ntej noj Irumed, lawv txo cov koob tshuaj uas tau siv yav dhau los. Kev kho mob pib nrog kev qhia txog 2.5 mg ntawm lisinopril ib hnub. Hauv yav tom ntej, cov tshuaj txhua hnub yog nce rau 10 mg.
- Mob myocardial infarction - noj 5 mg rau thawj hnub, tib lub koob tshuaj raug muab 48 teev tom qab thawj daim ntawv thov. Yav tom ntej, cov tshuaj raug coj ntawm 10 mg rau ib hnub twg rau 45 hnub.
Nrog ntshav qab zib
Cov neeg mob ntshav qab zib hom 1 thiab type 2 noj 10 mg ntawm lisinopril ib hnub.
Phiv fab ntawm Irumed
Kev kho mob txoj hnyuv
Digestive teeb meem uas tshwm sim thaum noj Irumed, yog manifested:
- qhov ncauj qhuav
- bouts ntawm xeev siab thiab ntuav;
- tsis qab los noj mov;
- kev puas tsuaj rau lub txiav;
- mob dyspeptic;
- cholestatic jaundice;
- o ntawm daim siab;
- mob plab.
Hematopoietic plab hnyuv siab raum
Cov tshuaj tuaj yeem pab txhawb kev tsis zoo ntawm lub cev muaj txiaj ntsig thiab muaj txiaj ntsig ntawm cov ntshav. Nrog rau kev siv lub sijhawm ntev, kuaj ntshav ntawm ntshav khov thiab ntshav tsis tuaj yeem txo.
Nruab nrab hauv lub paj hlwb
Cov nyhuv ntawm lisinopril ntawm lub paj hlwb tau manifested:
- mus ob peb vas hloov;
- txo qis rhiab ntawm qhov nqua;
- teeb meem tsaug zog;
- spasms ntawm plab hlaub nqaij leeg;
- leeg tsis muaj zog.
Los ntawm lub tshuab ua pa
Tawm tsam ntawm keeb kwm yav dhau los ntawm kev noj cov tshuaj, tawm tsam ntawm bronchial hawb pob thiab ua pa luv.
Los ntawm cov hlab plawv system
Cov cim ntawm kev puas tsuaj rau lub siab thiab cov hlab ntsha uas tshwm sim thaum noj Irumed:
- nias hauv siab mob siab;
- txo hauv kev ncig cov ntshav ntim ntau ntxiv;
- tus ntse txo cov ntshav siab;
- orthostatic cev qhuav dej;
- bradycardia;
- tachycardia;
- ua txhaum ntawm atrioventricular conduction;
- myocardial infarction.
Los ntawm ib sab ntawm cov metabolism
Thaum noj Irumed, ntshav ntau ntawm sodium, potassium, thiab bilirubin yuav nce. Cov kev ua ntawm hepatic transaminases tsis tshua hloov.
Kev ua xua
Kev tsis haum tshuaj rau cov tshuaj tau tshwm sim:
- o ntawm lub ntsej muag thiab lub larynx;
- khaus thiab liab ntawm daim tawv nqaij;
- ua pob ua ke rau hauv daim ntawv ntawm urticaria;
- anaphylactic poob siab.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj yuav ua rau kiv taub hau, uas txo qis kev xav. Yog li ntawd, nyob rau lub sijhawm kho, koj yuav tsum caiv tsis ua haujlwm nrog cov cuab yeej siv tau yooj yim.
Cov lus qhia tshwj xeeb
Siv rau lub sijhawm qub
Hauv kev kho kab mob ntshav siab nyob rau hauv cov neeg tshaj 65 xyoo, ntsiav tshuaj siv nrog ceev faj.
Txiag tej menyuam
Qhov kev tsis sib haum xeeb rau kev siv Irumed yog menyuam lub hnub nyoog (txog 18 xyoo).
Siv thaum cev xeeb tub thiab lactation
Thaum cev xeeb tub tshwm sim, kev kho mob nrog lisinopril yog nres tam sim ntawd. Cov tshuaj ua kom nquag nyob hauv cov mis thiab yuav cuam tshuam rau tus menyuam qhov mob, yog li koj yuav tsum tsis txhob haus tshuaj thaum lub sijhawm pub mis.
Daim ntawv thov rau lub raum khiav tsis zoo
Nrog kev mob raum tsis zoo, noj cov tshuaj yuav tsum tau soj ntsuam tas mus li ntawm cov ciaj ciam tseem ceeb.
Siv rau lub siab ua haujlwm tsis zoo
Hauv cov mob siab heev, cov tshuaj tsis raug xaj.
Noj ntau dhau ntawm Irumed
Thaum siv tshuaj loj ntawm lisinopril, ntshav siab poob qis, orthostatic vau nthuav dav. Muaj ib qho khaws cia ntawm cov zis thiab cov quav, nqhis dej heev. Nws tsis muaj cov tshuaj uas suppresses zoo ntawm lisinopril. Kev kho mob cuam tshuam nrog siv cov sorbents thiab laxatives, tso dej khov tshuaj ntsev.
Cov tshuaj muaj peev xwm tshem tawm los ntawm hemodialysis.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev siv tib txhij ntawm Irumed nrog:
- potassium-sparing diuretics thiab cyclosporine ntau tuaj yeem ua rau lub raum puas tsuaj;
- beta-blockers ua kom cov nyhuv hypotensive ntawm lisinopril;
- kev npaj lithium, qhov kev nthuav tawm ntawm tom kawg qeeb;
- antacids, qhov nqus ntawm cov tshuaj tiv thaiv kab mob tsis haum;
- cov piam thaj txo tshuaj ua rau muaj kev phom sij ntawm hypoglycemia;
- non-hormonal anti-inflammatory drugs hypotensive kev ua tau zoo ntawm lisinopril txo qis.
Cawv tau zoo
Kev haus dej cawv thaum kho mob cuam tshuam rau lub xeev ntawm lub zom zaub mov, genitourinary thiab lub paj hlwb.
Analogs
Cov tshuaj lag luam sib luag ntawm Irumed yog:
- Lisinopril;
- Diroton;
- Lisinotone;
- Lysiprex;
- Lysigamma.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Nws tsis yog yuav muaj peev xwm yuav tshuaj uas tsis muaj tshuaj.
Nqi
Tus nqi nruab nrab ntawm 30 ntsiav tshuaj yog 220 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj ntsiav tau khaws cia rau hauv qhov chaw txias, qhuav, tiv thaiv los ntawm kis lub teeb.
Hnub tas sij hawm
Yuav siv tau tsis pub dhau 36 lub hlis txij li hnub ntawm kev tsim khoom lag luam.
Chaw tsim tshuaj paus
Cov tshuaj yog tsim los ntawm lub tuam txhab tshuaj Belupo hauv Croatia.
Xyuas
Sofia, hnub nyoog 55 xyoo, Moscow: "Kuv tau mob ntshav siab ntev ntev. Lub siab raug ntau zuj zus, uas ua rau mob taub hau thiab tsis muaj zog. Kuv tsis xav noj tshuaj, yog li kuv tau sim ntau yam khoom noj uas tsis muaj txiaj ntsig. Cov kws kho mob tau qhia rau Irumed ntsiav tshuaj. Kuv pom qhov tshwm sim zoo. Hauv ib hlis. Rau ib nrab xyoo lub siab tau ceev tsis pub dhau qhov txwv tsis pub muaj. "
Tamara, hnub nyoog 59 xyoos, Narofominsk: "Niam tau mob ntshav qab zib tau ntev, thiab vim nws laus lawm, tus kab mob pib mob hnyav rau cov hlab ntsha thiab raum. Lub siab mob tas li, vim tias nws niam nquag mus rau tom tsev kho mob. Tus kws kho plawv qhia kuv kom yuav cov tshuaj Iramed. "Ib hnub ib zaug - qhov no txaus los tswj hwm qhov ib txwm muaj. Cov tshuaj pheej yig no tsis ua rau muaj kev phiv."