Yuav Siv Cov Tshuaj NovoMix 30 Penfill li cas?

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NovoMix 30 Penfill yog qhov tshuaj hypoglycemic raws li kev ua ntawm ob hom tshuaj insulin. Kev ua yeeb yaj kiab luv luv ua rau muaj txiaj ntsig rau qhov ua tiav sai sai ntawm kev kho mob, thaum insulin nrog qhov nruab nrab ntev tso cai rau koj los tswj cov nyhuv hypoglycemic thaum nruab hnub. Kev siv tshuaj insulin yog txwv tsis pub siv los ntawm cov neeg mob hnub nyoog qis dua 18 xyoo thiab raug tso cai siv los ntawm cov pojniam cev xeeb tub, lactating.

Lub Npe Tsis Yog Neeg Tsis Muaj Npe

Biphasic aspart ntawm insulin.

NovoMix 30 Penfill yog qhov tshuaj hypoglycemic raws li kev ua ntawm ob hom tshuaj insulin.

ATX

A10AD05.

Tso cov ntawv thiab cov nyob ua ke

Dosage form - ncua kev kawm ntawv rau subcutaneous thawj coj. 1 ml ntawm cov kua muaj 100 IU ntawm cov khoom siv sib xyaw ua ke, muaj 70% ntawm cov tshuaj insulin raws li muaju thiab 30% ntawm soluble aspart insulin. Txhawm rau nce cov nqi tshuaj pharmacokinetic, cov tshuaj pab tau ntxiv rau cov tshuaj nquag:

  • glycerol;
  • carbolic acid;
  • sodium tshuaj dawb thiab zinc;
  • metacresol;
  • dihydrogenated sodium hydrogen phosphate;
  • protamine sulfate;
  • sodium hydroxide;
  • 10% hydrochloric acid;
  • dej tsis huv rau kev txhaj tshuaj.

Cov tshuaj ntim rau hauv 3 ml cartridges muaj 300 IU ntawm cov tshuaj yeeb dej caw. NovoMix Penfill (Flexpen) tseem muaj nyob rau hauv cov qauv ntawm cov xaum xaws.

Pharmacological kev txiav txim

NovoMix sawv cev rau ib qho tshuaj insulin ob-theem, muaj cov qauv ntawm cov tshuaj tua neeg (pancreatic hormone):

  • 30% soluble luv-txaus ua yeeb yam;
  • 70% tshuaj tiv thaiv cov tshuaj insulin muaju nrog cov txiaj ntsig ib nrab hnub.

NovoMix qhia txog cov tshuaj insulin biphasic.

Cov tshuaj Insulin aspart yog tsim los siv DNA thev naus laus zis thev naus laus zis los ntawm kev ua haujlwm ntawm Baker tus poov xab.

Cov nyhuv ntshav hypoglycemic yog vim qhov khi ntawm aspart rau insulin receptors rau sab nraud ntawm myocytes thiab adipose cov nqaij mos. Nyob rau hauv tib si, kev txwv tsis pub cov gluconeogenesis nyob rau hauv daim siab tshwm sim thiab kev tso ntshav qab zib thauj ntau ntxiv. Raws li kev ua tiav ntawm kev ua kom muaj txiaj ntsig zoo, cov ntaub so ntswg ntawm lub cev muaj peev xwm nqus tau cov piam thaj thiab ua rau nws mus rau lub zog.

Cov nyhuv ntawm cov tshuaj yog pom rau 15-20 feeb, ncav lub siab tshaj plaws tom qab 2-4 teev. Cov nyhuv rau lub ntsej muag ntshav yuav nyob ntev li 24 teev.

Cov Tshuaj Pharmacokinetics

Vim tias muaj cov tshuaj aspartic acid, insulin aspart yog 30% ntau dua nqus mus rau hauv cov tawv nqaij subcutaneous txheej ntawm daim tawv nqaij, hauv kev sib piv rau cov tshuaj insulin. Thaum lawv nkag rau hauv cov hlab ntshav, cov tshuaj yeeb dej caw yuav dhia mus txog qhov ntau nyob hauv cov ntshav cov ntshav hauv 60 feeb. Qhov kev tshem tawm ib nrab-lub neej ua rau 30 feeb.

Qhov ntsuas ntawm insulin rov qab mus rau lawv qhov tseem ceeb hauv 15-18 teev tom qab kev tswj hwm ntawm sc. Cov tshuaj suav daws sib xyaw ua ke hauv cov nplooj siab thiab lub raum. Cov khoom lag luam tawm hauv lub cev tawm vim yog cov glomerular pom.

Thaum lawv nkag rau hauv cov hlab ntshav, cov tshuaj yeeb dej caw yuav dhia mus txog qhov ntau nyob hauv cov ntshav cov ntshav hauv 60 feeb.

Kev ntsuas rau siv

Kev kho tshuaj Insulin yog tsim rau cov mob hauv qab no:

  • insulin tiv ntshav qab zib;
  • cov ntshav qab zib tsis yog insulin-mob ntshav qab zib nrog qhov tsis muaj txiaj ntsig zoo ntawm kev noj zaub mov zoo, ua kom lub cev tawm dag zog thiab lwm yam kev ntsuas los txo lub cev qhov hnyav.

Cov Yuav Tsum Muaj

Cov tshuaj tsis tso cai rau tswj hwm rau cov neeg uas muaj kev cuam tshuam ntau ntxiv rau cov tshuaj lom neeg cov tshuaj uas ua rau cov neeg sawv cev hypoglycemic. Qhov insulin no tsis haum rau cov neeg tsis tau muaj 18 xyoo.

Nrog saib xyuas

Cov neeg mob uas lub cev ua tsis taus lub siab thiab lub raum thaum ua haujlwm ntawm cov tshuaj insulin yuav tsum saib xyuas lub xeev ntawm cov plab hnyuv siab raum. Lawv ua haujlwm tsis zoo tuaj yeem ua rau cov metabolism hauv insulin hloov siab.

Cov neeg uas muaj lub plawv khiav tsis zoo hauv lub hlwb thiab mob plawv sai yuav tsum tau ceev faj.

Cov neeg uas mob ntshav ncig ntawm lub hlwb yuav tsum tau ceev faj.

Yuav noj NovoMix 30 Penfill li cas

Cov tshuaj raug muab tsuas yog subcutaneously. Intramuscularly thiab intravenously txwv yog qhov tshwm sim uas yuav tshwm sim ntawm hypoglycemia.

Cov koob tshuaj yog txiav txim los ntawm tus kws kho mob nyob ntawm tus kheej qhov ntsuas ntawm cov piam thaj hauv ntshav thiab tus neeg mob xav tau cov tshuaj insulin. Cov neeg mob uas tsis muaj ntshav qab zib-insulin feem ntau yuav raug sau NovoMix raws li kev kho mob monotherapy nrog insulin thiab nrog cov tshuaj hypoglycemic. Txog ntshav qab zib hom 2, nws raug nquahu kom pib siv NovoMix nrog tshuaj ntau 6 lub sijhawm thaum sawv ntxov ua ntej noj mov thiab yav tsaus ntuj. Kev txhaj tshuaj yog tso cai nrog 12 units ntawm cov tshuaj rau ib qho kev txhaj tshuaj ib hnub ua ntej noj hmo.

Txoj Kev Insulin Blending

Ua ntej siv, nco ntsoov tias qhov ntsuas kub ntawm cov ntsiab lus ntawm daim cartridge phim rau qhov ntsuas kub ntawm ib puag ncig. Tom qab ntawd, sib xyaw cov tshuaj insulin raws li cov kev qhia hauv qab no:

  1. Thaum siv thawj zaug, dov lub thawv rau 10 zaug ntawm xib teg nyob rau hauv kab rov tav 10 npaug.
  2. Nqa lub pob txhav kab rov tav 10 npaug thiab txo nws txoj kev sau ua ntej kom lub pob lub pob txav mus raws tag nrho ntev ntawm daim cartridge. Txhawm rau ua qhov no, nws txaus txaus los khoov lub caj npab hauv lub lauj tshib sib koom tes.
  3. Tom qab ua tiav kev tswj hwm, qhov muab tshem tawm yuav tsum ua huab thiab tau txais tint dawb. Yog tias qhov no tsis tshwm sim, cov txheej txheem sib tov yog rov ua dua. Thaum cov kua tau ua kom sib xyaw lawm, cov kua dej yuav tsum tau txhaj tshuaj tam sim ntawd.

Txhua qhov kev qhia yog ua nrog rab koob tshiab.

Rau cov lus qhia ntawm qhov tsawg kawg ntawm 12 PIECES ntawm cov tshuaj nquag. Yog tias cov tshuaj insulin tsawg dua, tom qab ntawd koj yuav tsum hloov lub cartridge nrog lub tshiab.

Kev siv tus cwj mem uas qhwv siv

Ua ntej siv tus cwj mem, kos cov kev ua raws li hom insulin. Ua ntej txhaj thawj, nws yog tusyees tov.

Txhua qhov kev qhia yog ua nrog rab koob tshiab. Hloov cov caij nyoog yog qhov tsim nyog los txo qhov ntxim nyiam ntawm kev kis mob. Ua ntej siv, nco ntsoov tias rab koob tsis khoov lossis puas ntsoog. Txhawm rau txuas cov koob, koj yuav tsum ua raws li cov txheej txheem hauv qab no:

  1. Tshem tawm ntawm cov khoom tiv thaiv kev tiv thaiv los ntawm qhov khoom pov tseg, tom qab ntawd ntswj kom nrawm lub koob xaum xaum xaum rau.
  2. Lub hau sab nraud yog muab tshem tawm tab sis tsis pov tseg.
  3. Lawv tau hle lub hau puab.

Txawm hais tias txoj haujlwm zoo ntawm NovoMix, huab cua tuaj yeem nkag rau hauv lub laub. Yog li, ua ntej siv cov kua xaum xaum, nws yog qhov tsim nyog los tiv thaiv nws txoj kev nkag mus rau hauv cov ntaub so ntswg los ntawm kev ua yeeb yam hauv qab no:

  1. Hu 2 chav nrog tus xaiv koob tshuaj.
  2. Thaum tuav FlexPen tsa ncaj nrog rab koob sawv, coj mus rhaub maj mam rau ntawm daim cartridge nrog koj tus ntiv tes 4-5 zaug kom cov cua xa mus los rau saum toj ntawm daim cartridge.
  3. Txuas ntxiv tuav tus cwj mem syringe vertically, thawb lub pob valve txhua txoj kev. Txheeb xyuas tias cov koob tshuaj xaiv tau rov qab mus rau txoj hauj lwm 0 thiab qhov poob ntawm cov tshuaj tshwm rau qhov taub ntawm rab koob. Yog tias tsis muaj tshuaj, ces koj yuav tsum rov qab ua tus txheej txheem. Yog tias, tom qab 6 lub sijhawm, cov tshuaj insulin tsis nkag los ntawm rab koob, qhov no qhia tau hais tias yog FlexPen malfunction.

Ua ntej siv, nco ntsoov tias rab koob tsis khoov lossis puas ntsoog.

Qhov ntau npaum cas tau teeb tsa siv qhov koob tshuaj xaiv, uas yuav tsum pib ua haujlwm nyob rau 0. Tus xaiv rau kev txiav txim siab qhov ntau npaum li cas tuaj yeem tig ob qho tib si moos thiab counterclockwise. Tab sis hauv cov txheej txheem koj yuav tsum tau ceev faj - koj tsis tuaj yeem nias lub pob pib, tsis li ntawd yuav muaj kev tawm ntawm insulin. Tus lej 1 sib raug mus rau 1 chav tsev ntawm insulin. Tsis txhob teev tshuaj ntau dua qhov nyiaj ntawm cov insulin tshuav hauv daim laub ntawv.

Txhawm rau txhawm rau txhaj tshuaj, koj yuav tsum nias lub pob nyem txhais txoj kev kom txog thaum txoj hauj lwm 0 tso tawm kom pom ntawm tus xaiv thiab thaum lub koob tseem nyob hauv qab daim tawv. Tom qab teeb lub xoom txoj hauj lwm ntawm tus xaiv, tawm hauv rab koob ntawm daim tawv nqaij tsawg kawg 6 vib nas this, vim tias cov tshuaj insulin yuav ua kom tiav. Thaum lub sij hawm qhia tawm, tus xaiv yuav tsum tsis pub kom tig, vim tias thaum nws tig, insulin yuav tsis raug tso tawm. Tom qab cov txheej txheem, muab cov koob tso rau hauv lub hau sab nraud thiab unscrew.

Phiv los ntawm NovoMix 30 Penfilla

Cov kev xav tsis zoo nyob rau hauv feem ntau muaj kev npau taws los ntawm kev xaiv qhov ntau thiab kev siv tshuaj tsis raug.

Ntawm ib feem ntawm cov khoom hauv nruab nrog kev pom

Ophthalmic ntshawv siab yog nrog txoj kev txhim kho ntawm txoj kev tsis zoo thiab mob ntshav qab zib.

Nruab nrab hauv lub paj hlwb

Kev tsis sib haum xeeb ntawm cov hlab ntsha yog cov yam ntxwv tsis tshua muaj tshwm sim los ntawm kev pom ntawm cov kab mob peripheral polyneuropathy. Tej zaum kev txhim kho kiv taub hau thiab mob taub hau.

NovoMix 30 Penfill tuaj yeem ua rau kiv taub hau.

Ntawm ib sab ntawm daim tawv nqaij

Txhaj tshuaj subcutaneous yuav tsum tau muab tso rau hauv qhov chaw sib txawv hauv tib thaj chaw kom tiv thaiv kev tiv thaiv lipodystrophy. Tej zaum qhov pom tshwm sim ntawm qhov tshwm sim ntawm qhov chaw txhaj tshuaj - o lossis liab. Kev ua xua rau qhov ua pob lossis khaus khaus tawm mus lawv tus kheej thaum muab tshuaj rau txo lossis cov tshuaj kho mob.

Los ntawm lub cev tiv thaiv kab mob

Kev tiv thaiv kab mob tsis haum nrog lub ntsej muag yog:

  • urticaria;
  • khaus tawv nqaij;
  • ua pob
  • lub plab zom mov;
  • ua pa nyuaj
  • nce hws.

Los ntawm ib sab ntawm cov metabolism

Kev tsis haum xeeb hauv lub cev yog ua rau poob los ntawm kev tswj glycemic. Kev txhim kho ntawm hypoglycemia tsis raug cais tawm, tshwj xeeb tshaj yog nrog cov mus tib seem kev siv tshuaj ntawm qhov ncauj hypoglycemic.

Cov neeg mob predisposed rau anaphylactic kev tig rov qab yog qhov pheej hmoo ntawm kev nthuav dav anaphylactic.

Kev ua xua

Hauv cov neeg mob predisposed rau qhov tshwm sim ntawm anaphylactic kev tig rov qab, muaj kev pheej hmoo ntawm anaphylactic poob siab, angioedema ntawm tus nplaig, caj pas, thiab lub suab nrov. Nrog rau ib tug neeg intolerance mus rau yam ntxwv, tawv nqaij tshwm sim.

Cov lus qhia tshwj xeeb

Nrog rau kev siv tshuaj tsis txaus ntawm hypoglycemic tus neeg sawv cev lossis nrog ntse tshem ntawm kev kho mob, hyperglycemia tuaj yeem tsim kho. Muaj cov ntshav qabzib ntau nyob hauv siab tuaj yeem ua rau ketoacidosis muaj ntshav qab zib yog tias tus neeg mob tsis tau txais kev kho mob kom tsim nyog. Txoj kev pheej hmoo ntawm kev txhim kho cov txheej txheem pathological nce ntxiv hauv cov neeg mob uas muaj ntshav qab zib hom 1. Hyperglycemia yog tus cwj pwm los ntawm cov tsos mob ntawm cov tsos mob li no:

  • nqhis dej heev;
  • polyuria nrog kev tso zis nce ntxiv;
  • liab liab, tev, tawv tawv;
  • pw tsaug zog;
  • mob nkees ntev;
  • xeev siab thiab ntuav;
  • qhuav cov qog ua pa ntawm qhov ncauj;
  • hnov ntxhiab tsw ntxhiab ntawm acetone thaum ua pa tawm.
Hyperglycemia yog tus cwj pwm los ntawm cov tsos ntawm kev nqhis dej heev.
Hyperglycemia yog tus cwj pwm ntawm xeev siab thiab ntuav.
Hyperglycemia yog tus cwj pwm los ntawm kev pw tsaug zog tsis zoo.
Hyperglycemia yog tus cwj pwm mob los ntawm mob nkees.

Nrog rau kev ua kom lub cev ntau ntxiv, tsis ua raws li kev noj zaub mov noj los yog hla kev txhaj tshuaj, hypoglycemia yuav loj hlob tuaj.

Siv rau lub sijhawm qub

Cov neeg mob uas laus dua 65 xyoos tsis tas yuav kho qhov koob.

Teem sijhawm NovoMix 30 Penfil rau menyuam yaus

Nws yog txwv tsis pub txhaj tshuaj rau cov menyuam yaus hnub nyoog qis dua 18 xyoo vim muaj cov ntaub ntawv tsis txaus ntawm kev cuam tshuam ntawm cov tshuaj insulin ntawm kev ua haujlwm ntawm cov kabmob hauv cov menyuam yaus thiab cov hluas.

Siv thaum cev xeeb tub thiab lactation

Kev kho tshuaj Insulin pab txo qis qab zib rau cov poj niam thaum cev xeeb tub. Aspart ntawm insulin tsis cuam tshuam rau ntuj txoj kev loj hlob ntawm lub cev thiab tsis ua rau mob plab intrauterine. Cov tshuaj tsis kis mus rau niam mis, yog li nws tuaj yeem siv thaum lactation.

Kev Siv ເກີນ NovoMix 30 Penfill

Nrog kev tsim txom ntawm cov tshuaj hypoglycemic, cov cim qhia ntawm kev haus ntau dhau yuav tshwm sim. Cov duab hauv tsev kho mob tau pom los ntawm maj mam los yog txoj kev loj hlob ntawm hypoglycemia, nyob ntawm seb muab ntau npaum li cas. Nrog rau qhov qab zib tsawg dua, koj tuaj yeem tshem tawm cov kab mob pathological koj tus kheej los ntawm kev noj cov piam thaj, confectionery lossis cov zaub mov uas muaj cov khoom noj uas muaj carbohydrate. Vim tias qhov tshwm sim ntawm cov ntshav qab zib tsawg, nws pom zoo kom cov neeg mob ntshav qab zib nqa cov zaub mov qab zib nrog lawv.

Thaum muaj mob ntshav nce siab ntau dhau, tus neeg mob tsis nco qab lawm.

Thaum muaj mob ntshav nce siab ntau dhau, tus neeg mob tsis nco qab lawm. Thaum muaj xwm txheej ceev, nws yuav tsum tau txhaj tshuaj rau lub cev lossis 0,5 ntawm 1 mg ntawm glucagon nyob rau hauv chaw mob, 40% kev daws teeb meem tuaj yeem muab tshuaj yog tias tus neeg mob nco qab tsis tau rov qab.

Kev cuam tshuam nrog lwm yam tshuaj

Tsis muaj kev sib piv hauv kev kho mob ntawm NovoMix nrog rau lwm cov tshuaj tau tshwm sim thaum lub sijhawm kuaj mob. Kev siv mus tib seem siv lwm yam tshuaj ua rau muaj kev nce ntxiv lossis txo qis hauv cov nyhuv hypoglycemic.

Cov tshuaj uas txhim kho glycemic nyhuv ntawm NovoMixCov tshuaj kho uas ua kom lub cev kho tsis muaj zog
  • monoamine oxidase, angiotensin hloov mus rau enzyme thiab carbonate dehydratase blockers;
  • tsis xaiv neeg beta-adrenoreceptor inhibitors;
  • tetracycline tshuaj tua kab mob;
  • Clofibrate;
  • cov khoom siv lithium;
  • Cyclophosphamide;
  • salicylates;
  • Theophylline;
  • tshuaj steroid.
  • tshuaj tiv thaiv kom txhob muaj tshuaj estrogen;
  • glucocorticosteroids;
  • tshuaj diuretic;
  • sympathomimetics;
  • tshuaj tiv thaiv kab mob;
  • Clonidine;
  • nicotine;
  • cov thyroid hormones;
  • analgesics;
  • Danazole

Cawv tau zoo

Ethanol ua rau muaj kev tiv thaiv ntawm cov glycemic tswj ploj. Cov dej cawv ua kom zoo dua lossis txo qhov cuam tshuam ntawm cov tshuaj, yog li koj yuav tsum tsis txhob haus dej cawv thaum kho.

Kev siv mus tib seem siv lwm yam tshuaj ua rau muaj kev nce ntxiv lossis txo qis hauv cov nyhuv hypoglycemic.

Analogs

Hloov mus rau lwm hom tshuaj insulin yog ua tiav los ntawm kev saib xyuas mob nkeeg nruj me ntsis. Los ntawm analogues paub qhov txawv:

  • Vosulin;
  • Gensulin;
  • Insuvit;
  • Insugen;
  • Insuman;
  • Mikstard;
  • Neej Neeg Dab.

Cov ntsiab lus ntawm lub tsev muag tshuaj tawm

Cov tshuaj yuav tuaj yeem yuav ntawm cov tshuaj noj.

Kuv tuaj yeem yuav yam tsis tas yuav tshuaj

Nrog rau kev siv cov tshuaj tsis raug cai, muaj ntshav qab zib tsawg tuaj yeem tsim kho, yog li, kho mob insulin yam tsis muaj kev qhia ncaj qha rau kev kho mob yog txwv tsis pub.

Nqi

Tus nqi nruab nrab rau tus sawv cev hypoglycemic yog 1821 rubles.

Cia rau cov neeg mob rau cov tshuaj

Cov pob txha taub ntawv yog cia rau hauv qhov chaw tsaus ntawm qhov kub ntawm + 2 ... + 8 ° C yam tsis muaj kuab.

Hnub tas sij hawm

2 xyoos

Chaw tsim tshuaj paus

Novo Nordisk, Denmark.

Tshuaj insulin Novomix
NovoMix 30 Penfill

Xyuas

Tatyana Komissarova, 22 xyoo, Yekaterinburg

Thaum cev xeeb tub, muaj kab mob ntshav qab zib hauv lub cev, vim qhov kuv ua raws kev noj zaub mov nruj nrog khaws cia chaw khaws cia thiab suav lub khob cij. Tab sis qhov no tsis pab: tom qab noj cov piam thaj tau nce mus txog 13 mmol. Tus kws kuaj mob endocrinologist tau muab Kev Tiv Thaiv Kev Kho Mob NovoMix, thiab nws txwv tsis pub haus cov tshuaj hyperglycemia. Raug muag 2 zaug hauv ib hnub 5 feeb ua ntej noj mov thiab Levemir 2 units ua ntej yuav mus pw. Kuv kawm siv rab koob txhaj tshuaj, vim tias nws yooj yim dua li kev txhaj tshuaj. Txoj kev daws teeb meem tsis ua rau kub nyhiab, tab sis qee zaum tshwm sim bruises. Qab zib rov qab sai sai. Kuv tawm hauv qhov kev tshuaj xyuas zoo.

Stanislav Zinoviev, 34 xyoo, Moscow

2 xyoos txhaj tshuaj NovoMix insulin. Kuv muaj ntshav qab zib hom 2, yog li kuv tsuas yog siv phwj tshuaj thiab tsis noj tshuaj. Cov tshuaj txo cov piam thaj rau 6.9-7.0 mmol thiab tuav 24 teev. Yog tias koj hla kev txhaj tshuaj, tom qab ntawv qhov no tsis yog qhov tseem ceeb - cov tshuaj tuaj yeem siv nrog lwm hom tshuaj insulin.Qhov loj tshaj plaws yog tias lub koob tshuaj yuav tsum tau ua raws li cov lus qhia.

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