Amoxiclav 500 mg yog ib qho ntawm kev coj ua ntawm cov sib xyaw ua ke tua kab mob. Qhov no vim nws txoj kev ua tau zoo, kev zam zoo los ntawm cov neeg mob feem ntau thiab muaj cov ntawv tso tawm ntau yam.
ATX
Cov tshuaj muaj ATX code J01CR02.
Amoxiclav 500 mg yog ib qho ntawm kev coj ua ntawm cov sib xyaw ua ke tua kab mob.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj muaj nyob hauv daim ntawv ntawm:
- plab hnyuv taum coated ntsiav tshuaj;
- hmoov rau qhov kev npaj ntawm qhov ncauj ncua ntawv;
- hmoov npaj rau kev txhaj tshuaj.
Tseem rau ntawm kev muag khoom yog dispersible ntau yam ntawm cov ntsiav tshuaj (Amoxiclav Quicktab).
Cov tshuaj muaj pes tsawg leeg suav nrog 2 yam ua haujlwm: cov tshuaj tua kab mob amoxicillin thiab the-lactamase inhibitor clavulanic acid. Kev xaiv ncua nyob rau hauv ib daim li ntawm 500 mg yog tsis ua neeg. Amoxicillin trihydrate yog siv rau cov tshuaj ntawm qhov ncauj, thiab nws cov ntsev ntsev yog siv rau kev txhaj tshuaj.
Cov ntsiav tshuaj Enteric-soluble muaj 125 mg ntawm cov kab mob enzyme inhibitor nyob rau hauv daim ntawv ntawm poov tshuaj clavulanate. Amoxicillin tej zaum yuav muaj li 250, 500 mg lossis 875 mg.
Cov tub ntxhais sib ntxiv:
- talc;
- croscarmellose sodium;
- anhydrous silicon dioxide colloid;
- magnesium stearate;
- povidone;
- microcellulose.
Lub plhaub yog ua los ntawm hypromellose, talc thiab titanium oxide nrog ntxiv ntawm polysorbate 80, triethyl citrate thiab ethyl cellulose ether. Qhov txheej txheem no muaj cov khoom tawm tsam thiab ua rau txoj hnyuv hauv plab zom mov. Cov ntsiav tshuaj raug muag hauv blisters lossis iav vials. Cov thawv ntim khoom.
Cov ntsiav tshuaj tsis haum tej zaum yuav muaj ntau qhov sib txawv ntawm clavulanate thiab tshuaj tua kab mob, suav nrog 125 mg + 500 mg. Sib sau muaj xws li:
- microcrystalline cellulose;
- silica;
- chaw muag tshuaj;
- polyethylene glycol;
- ferric oxide (E172);
- sweetener;
- tsw.
Cov khoom ntim tau rau hauv cov hlwv ntawm 10 lossis 14 pcs. Cov thawv ntawv cardboard muaj 2 blister daim hlau thiab cov ntawv uas muaj cov lus qhia rau kev siv.
Daim ntawv hno cov tshuaj yog cov hmoov dawb lossis xim daj uas muaj kev sib xyaw ntawm sodium amoxicillin nrog rau cov tshuaj nyob hauv qhov sib piv ntawm 5: 1. Nws muaj qhov ua kom tiav ntawm 0.5 g + 0.1 g lossis 1 g + 0.2 g. Cov tshuaj muab tso rau hauv vials. Lub thawv muaj 5 lub raj mis zoo li no thiab cov ntawv qhia kev qhia.
Pharmacological kev txiav txim
Amoxiclav yog cov tshuaj tua kab mob tiv thaiv kab mob. Kev kho mob nyhuv ntawm cov tshuaj yog muab los ntawm cov tshuaj tiv thaiv antibacterial tiv thaiv amoxicillin. Clavulanate nthuav dav ntau yam ntawm kev nqis tes ua, tab sis tsis muaj cov khoom ua antimicrobial.
Nyob rau hauv kev cuam tshuam ntawm cov tshuaj, lub zog ntawm phab ntsa cell poob qis, uas ua rau tuag lub cev.
Amoxicillin yog qhov thaiv ntawm cov kab mob transpeptidase enzymes, tsis muaj qhov biosynthesis ntawm lub ntsiab txheej txheem ntawm lub murein membrane hauv cov kab mob tsis yooj yim sua. Nyob rau hauv kev cuam tshuam ntawm cov tshuaj, lub zog ntawm phab ntsa cell poob qis, uas ua rau tuag lub cev. Qee cov kab mob kis tau tiv thaiv kev tiv thaiv ntawm cov tshuaj tua kab mob, vim tias lawv tau kawm los tsim cov β-lactamases, uas rhuav tshem nws cov qauv. Txhawm rau tsis ua haujlwm cov enzymatic sib txuas hauv cov muaj pes tsawg leeg ntawm Amoxiclav thiab clavulanate tau qhia.
Ua tsaug rau kev sib koom tes ua haujlwm ntawm cov tshuaj yeeb dej caw, cov tshuaj muaj peev xwm daws tau ntau yam kabmob sib kis tau tshwm sim los ntawm cov kab mob sib kis xws li:
- staphylococci;
- Salmonella
- hemophilic bacillus;
- mob chlamydia
- streptococci;
- clostridia;
- enterobacteria;
- gono- thiab meningococci;
- Ntxaug Yaj
- Cuam Tshuam
- legionella;
- E. coli;
- mob hnoos qhuav;
- daj ntseg treponema;
- pob tsuas;
- Helicobacter pylori;
- Preotellas thiab lwm yam
Cov Tshuaj Pharmacokinetics
Thaum noj cov tshuaj ntawm qhov ncauj, nws cov nquag ua haujlwm yog nqus los ntawm txoj hnyuv tag nrho hauv 60-90 feeb. Lawv qhov nruab nrab nruab nrab nce mus txog 70%, thiab qhov siab tshaj plaws ntshav plahaum nyob ntawm cov koob tshuaj siv.
Thaum noj cov tshuaj ntawm qhov ncauj, nws cov nquag ua haujlwm yog nqus los ntawm txoj hnyuv tag nrho hauv 60-90 feeb.
Cov tshuaj tau zoo faib rau hauv cov kua nruab nrog cev thiab ntau cov ntaub so ntswg. Nws tuaj yeem kov yeej qhov teeb meem placental, yog pom muaj ntau me me hauv cov muaj pes tsawg leeg niam mis, tab sis tsis muaj peev xwm kov yeej BBB thaum tsis muaj mob hauv zos. Cov kev sib txuas nrog cov qauv protein ntawm cov ntshav muaj ntsis (kwv yees li 20%), yog li cov tshuaj ntau dhau yuav raug tshem tawm los ntawm hemodialysis.
Feem ntau ntawm cov tshuaj (nce txog 65-70%) raug tso tawm los ntawm lub raum hauv lawv thawj daim ntawv hauv 6 teev, thaum clavulanic acid nquag tawg thiab ua rau hauv thawj 2-3 teev tom qab kev tswj hwm. Amoxicillin, hauv kev sib piv rau nws, nws yog me ntsis kev cuam tshuam rau cov metabolism. Cov khoom ua kom lwj yog cov siv tsis tau, ua rau feem ntau yog nyob rau hauv qhov muaj pes tsawg leeg cov zis, ib feem nrog quav.
Qhov nruab nrab ib nrab-lub neej ntawm cov khoom siv nquag yog 1 teev. Hauv cov neeg mob uas mob raum tsis ua haujlwm, tus neeg sawv cev ntawm tus kws kho mob no tau tso zis ntau zaus ntev dua, yog li, kev txo tshuaj thiab / lossis tsawg zaus ntawm kev tswj hwm nws yuav tsum ua.
Kev ntsuas rau siv
Amoxiclav raug samfwm kom tshem tawm cov kabmob ua los ntawm pathogens nkag siab nws.
Amoxiclav 500 siv coj los kho mob txhaws.
Nws yog siv:
- hauv kev kho hniav;
- nrog cov kab mob ua pa thiab kab mob ntawm cov qis ntawm cov kab mob ua pa, nrog rau mob ntsws;
- rau kev kho mob ntawm tonsillitis, otitis media, sinusitis thiab lwm yam mob otolaryngological txhab;
- nrog rau mob peritonitis, muaj kab mob ntawm txoj hnyuv thiab hauv plab;
- nyob rau hauv urology thiab gynecology;
- los tua cov kab mob gonorrhea thiab chancroid;
- nrog cov tawv nqaij thiab cov leeg mob;
- nrog kev kis mob ntawm articular ntsiab thiab pob txha nqaij;
- nrog cov kab mob dav dav thiab sib xyaw.
Cov tshuaj tseem tuaj yeem siv rau kev tiv thaiv, piv txwv, hauv lub sijhawm ua haujlwm tom qab.
Cov Yuav Tsum Muaj
Nruj contraindications rau sau ntawv muab tshuaj muaj xws li:
- kev tsis qaug rau tus kheej, suav nrog ib qho ntawm cov khoom siv ntxiv;
- kev fab tshuaj tsis haum rau penicillin, nws cov tshuaj tiv thaiv kab mob, carbapenems lossis cephalosporin npaj;
- keeb kwm txog kab mob siab thiab mob daj ntseg, tsim tawm los ntawm kev siv tshuaj tua kab mob;
- lymphocytic leukemia;
- mob ntsws lymphoblastosis.
Cov poj niam cev xeeb tub thiab lactating, cov neeg mob uas lub raum tsis zoo thiab / lossis lub siab ua haujlwm, nrog rau pseudomembranous colitis yuav tsum tau ua tib zoo xaiv cov koob tshuaj thiab kev tshuaj xyuas tshwj xeeb.
Cov ntsiav tshuaj Quicktab kuj tseem tuaj yeem tsis raug siv rau phenylketonuria.
Cov poj niam cev xeeb tub xav tau kev xaiv ua tib zoo tshuaj ntawm Amoxiclav 500 thiab kev kuaj mob tshwj xeeb.
Yuav noj Amoxiclav 500 npaum li cas
Cov txheej txheem ntawm kev kho mob, kev noj tshuaj thiab lub sijhawm siv tshuaj yog txiav txim los ntawm tus kws kho mob, xam rau hauv tus neeg mob lub hnub nyoog, qhov mob hnyav, pom qhov muaj zog, qhov cuam tshuam nrog tshuaj. Yog li, nws tsis tuaj yeem siv yeeb tshuaj rau tus kheej tshuaj.
Cov ntsiav tshuaj nrog lub plab zom khoom noj yuav tsum tau nqos tag nrho, ntxuav kom huv nrog dej, thiab cov ntsiav tshuaj uas tawg yuav tsum nqus kom txog thaum yaj tag. Nws raug nquahu kom siv cov tshuaj nrog zaub mov los tiv thaiv lub plab hnyuv tawm ntawm nws cov kev ua kom khaus.
500 mg + 100 mg txhaj tshuaj concentrate yog yaj hauv 10 ml dej rau kev txhaj tshuaj. Kev daws yog txhaj rau hauv cov leeg maj mam. Txuas ntxiv txhawm rau tsim nyog tau txais cov hnoos qeev ua kua. Tom qab tshem tus mob hnyav ntawm tus neeg mob, lawv raug pauv mus rau hauv lub qhov ncauj ntawm Amoxiclav.
Rau menyuam
Mus txog 6 xyoo, nws raug nquahu kom muab tshuaj rau tus neeg mob ua lub cev tawm hauv qhov ncauj. Koob tshuaj yog xam ib tus zuj zus. Lub hnub nyoog txwv rau cov ntsiav tshuaj dispersible yog 12 xyoos. Cov menyuam yaus hnub nyoog dhau 12 xyoos, yog tias lawv lub cev tsis hnyav dua 40 kg, noj cov koob tshuaj zoo ib yam li cov neeg laus.
Rau cov laus
500 mg + 125 mg ntsiav tshuaj tuaj yeem siv rau cov neeg laus thiab menyuam ntxhais hnub nyoog 12 xyoos thiab laus dua. Feem ntau lawv haus thaum muaj 12-teev sib nrug. Hauv kev kis mob hnyav thiab mob ua pa, lawv tau noj txhua 8 teev.
Pes tsawg hnub rau noj
Tom qab tshem tawm cov tsos mob pom, kev kho mob yuav tsum tsis txhob tsum nyob rau 2-3 hnub tom ntej. Qhov nruab nrab ntawm kev kho mob yog los ntawm 5 hnub txog 2 lub lis piam. Tom qab mus ntsib tus kws kho mob thib ob, chav kho mob yuav tsum txuas ntxiv.
Noj cov tshuaj rau ntshav qab zib
Tsis muaj kev tiv thaiv dab tsi rau kev noj tshuaj rau ntshav qab zib. Kev siv tshuaj rau cov qauv yog siv, tab sis ib lub sijhawm ntev ntawm kev siv tshuaj tua kab mob tej zaum yuav tsum tau.
Ntawm cov mob ntshav qab zib mellitus, siv cov tshuaj Amoxiclav ntau kawg, tab sis siv sijhawm ntev los kho tshuaj tua kab mob tej zaum yuav tsum tau ua.
Sab sij huam
Feem ntau, qhov tsis xav tau qhov tsis txaus ntseeg thiab tsis tas yuav tsum tsis ua haujlwm ntxiv.
Kev kho mob txoj hnyuv
Kev tawm tsam ntawm xeev ntuav, tsis qab los noj mov, dyspepsia, mob plab, ntuav, stomatitis, enterocolitis, raws plab, mob plab, lub siab ua haujlwm tsis zoo, nce siab kev ua haujlwm ntawm daim siab enzymes. Cov hniav tuaj yeem tsaus ntuj, txheej tsaus ntawm daim nplaig tuaj yeem tshwm sim.
Hematopoietic plab hnyuv siab raum
Kev tsuj ntawm cov pob txha pob txha muaj nuj nqi, hloov ntshav sib xyaw, nrog rau thrombocytosis thiab hemolytic anemia, thim rov qab hemophilia.
Nruab nrab hauv lub paj hlwb
Cov migraines, tsis muaj zog, kiv taub hau, ntxhov siab, hyperactivity, kev xav dhau hwv, pw tsis taus. Kev pom zoo tuaj yeem tshwm sim, lawv qhov tshwm sim muaj qhov siab tshwj xeeb tshaj yog nrog lub raum tsis ua haujlwm lossis kev qhia ntawm kev noj tshuaj loj.
Los ntawm cov kab mob zis
Yuav ua tau nephropathy, hematuria, crystallization ntawm cov ntsev hauv cov zis.
Kev ua xua
Kev ua haujlwm rau lub cev, hyperemia, khaus, urticaria, o, erythema multiforme lossis malignant, exfoliative dermatitis, Lyell syndrome, exanthema, vasculitis, anaphylactoid tshua, mob ntawm qhov chaw txhaj tshuaj.
Cov lus qhia tshwj xeeb
Cov cuab yeej no tsis yog siv los kho cov neeg mob mononucleosis, vim tias nws tuaj yeem ua rau mob pob khaus liab.
Thaum siv tshuaj loj ntawm Amoxiclav rau kev tiv thaiv crystalluria, yuav tsum pom kev haus dej haus zoo.
Thaum lub sij hawm kho cov tshuaj tua kab mob, yuav tsum saib xyuas lub xeev ntawm lub raum-hepatic cov qauv thiab lub cev sib xyaw ntawm cov ntshav yog tsim nyog.
Cov tshuaj tuaj yeem ua rau pom kev zoo ntawm kev ua haujlwm siab, c. suav nrog kev kho tus mob vaginitis, stomatitis, tawv nqaij mycoses. Yog tias muaj qhov siab ntawm cov tshuaj tua kabmob rau penicillin ntau, hla kev ua xua nrog cephalosporins yog ua tau.
Thaum siv tshuaj loj ntawm Amoxiclav rau kev tiv thaiv crystalluria, yuav tsum pom kev haus dej haus zoo. Txhawm rau kom tsis txhob mob pseudo-tau zoo thaum kuaj cov zis rau cov piam thaj, ib qho kev ntsuas glucosidase yuav tsum siv.
Nrog kev siv tshuaj tua kab mob, yuav tsum tau txiav cov tshuaj tua kab mob. Tshem tawm kev mob raws plab nrog cov tshuaj uas thaiv plab hnyuv, yog contraindicated.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Vim tias kev pheej hmoo ntawm lub hlwb kev xav, yuav tsum tau saib xyuas thaum tsav tsheb lossis sib koom nrog cov kev pheej hmoo.
Daim ntawv thov rau lub raum khiav tsis zoo
Yog tias qib creatinine nyob hauv thaj tsam 10-30 ml / min, ces ntau li 500 mg + 125 mg tau noj tsis ntau tshaj 2 zaug hauv ib hnub. Nrog cov qib creatinine qis dua 10 ml / min, qhov sib txawv ntawm cov tshuaj tau ntxiv rau 24 teev.
Siv rau lub siab ua haujlwm tsis zoo
Nrog daim siab ua haujlwm, koj yuav tsum ua tib zoo xaiv lub koob tshuaj, saib xyuas tus neeg mob lub sijhawm.
Nrog daim siab ua haujlwm, koj yuav tsum ua tib zoo xaiv lub koob tshuaj ntawm Amoxiclav.
Siv thaum cev xeeb tub thiab lactation
Cov poj niam cev xeeb tub thiab cov niam laus tuaj yeem siv cov tshuaj tsuas yog sab laj nrog kws kho mob. Thaum lub sij hawm tswj hwm ntawm Amoxiclav, kev pub mis ntuj yuav tsum tau muab pov tseg.
Noj ntau dhau
Yog tias cov tshuaj noj tau ntau dua, cov hauv qab no yuav tshwm sim:
- mob taub hau
- dyspepsia
- xeev siab
- plab zom mov;
- ntuav
- cramps
- kev suav nyiaj tshaj;
- kev pw tsaug zog;
- kev tsis zoo
Nws raug nquahu kom ntxuav lub plab kab noj hniav thiab noj enterosorbent. Kev kho cov tsos mob yog tau kho. Hauv kev siv tshuaj ntau tshaj plaws, hemodialysis ua.
Hauv kev siv tshuaj ntau dhau nrog Amoxiclav, kev kuaj mob hemodialysis tau ua.
Kev cuam tshuam nrog lwm yam tshuaj
Nyob rau hauv muaj cov ascorbic acid, nqus ntawm cov yam muaj sia ntawm cov tshuaj yog kho kom zoo. Antacids, laxatives, aminoglycoside tus neeg sawv cev thiab glucosamine qeeb cov txheej txheem ntawm lawv qhov kev nqus. Amoxicillin concentration hauv ntshav nce ntxiv nrog kev siv tshuaj ib txhij nrog NSAIDs, diuretics, Probenecid, Phenylbutazone, Allopurinol.
Ua ke nrog Amoxiclav, qhov kev mob tshwm sim ntawm Methotrexate, Disulfiram, Allopurinol tau txhim kho, nws yog qhov ua tau kom nce ntawm cov nyhuv ntawm kev tiv thaiv tsis ncaj thiab ua kom tsis muaj zog ntawm kev sib pauv tshuaj estrogen. Sulfanilamides thiab tshuaj tua kab mob bacteriostatic yog nws qhov kev tawm tsam, thiab kev sib koom tes nrog rifampicin txo cov kev ua tau zoo ntawm ob qho tshuaj.
Cov npe ntawm Amoxiclav 500
Raws li hloov chaw rau cov cuab yeej no, koj tuaj yeem siv cov tshuaj no:
- Flemoklav Solutab;
- Amoxicillin + Clavulanic acid;
- Augmentin;
- Verklav;
- Clamosar;
- Amoxivan;
- Rapiclav;
- Ranklav;
- Arlet thiab lwm cov khoom sib piv.
Amoxiclav 500 Lub Tsev Muag Tshuaj Cov Nyiaj So Haujlwm
Cov tshuaj nyob hauv cov lus nug tsis muaj nyob ywj siab.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Daim ntawv yuav tshuaj yuav tsum tau yuav txhua yam tshuaj.
Nqi
Tus nqi ntawm cov ntsiav tshuaj hauv ib zaj duab xis txheej yog los ntawm 326 rubles. rau 15 pcs. 500 mg + 125 mg. Tus nqi ntawm 500 mg + 100 mg txhaj tshuaj mloog zoo thaj tsam 485 rubles. rau 5 koob tshuaj.
Cia rau cov neeg mob rau cov tshuaj
Kev tiv thaiv ncaj qha rau lub hnub ci hluav taws xob, qhov kub siab thiab qhov kub siab tshaj + 25 ° C yuav tsum tsis tso cai. Cov tshuaj yuav tsum tsis txhob muaj rau cov menyuam.
Hnub tas sij hawm
Cov ntsiav tshuaj uas tsis pom zoo tau khaws cia rau 3 xyoos txij li hnub kev tsim khoom. Lub txee lub neej rau tag nrho lwm cov qauv ntawm Amoxiclav yog 2 xyoos. Siv tsis tau cov tshuaj uas muaj hnub nyoog lawm.
Amoxiclav 500 Xyuas
Cov tshuaj no tau txais ntau cov lus qhia zoo. Cov kev ntsuas tsis zoo tau cuam tshuam nrog tus neeg lub cev cov tshuaj tiv thaiv lossis tsis txaus siab ntawm qee hom kab mob.
Cov kws kho mob
Kornilin A.A., urologist, Volgograd
Ib qhov tshuaj tiv thaiv zoo penicillin nrog rau kev pom ntxiv ntev. Ua tau zoo rau cystitis, nephritis, urethral syndrome. Kuv pom zoo kom coj nws mus tib seem nrog cov neeg ua hauj lwm probiotic.
Piskarchuk E. G., cov kws kho mob dav dav, Smolensk
Ib qho tshuaj zoo los tawm tsam ntau cov kis mob thiab mob. Tsis muaj cov kev mob tshwm sim tom qab siv tshuaj rau kuv qhov kev xyaum, yog li kuv xav tias nws yog cov tshuaj tua kab mob zoo.
Daim ntawv yuav tshuaj yuav tsum tau yuav txhua yam tshuaj.
Cov neeg mob
Tamara, 59 xyoo, Vyazma
Pheej yig tshuaj uas pab koj sai sai ntawm koj txhais taw. Kuv coj lawv nrog exacerbations ntawm mob ntsws ntev. Cov tshuaj muaj peev xwm tiv taus zoo yog tias noj nrog zaub mov. Txwv tsis pub, muaj qhov tsis xis nyob hauv plab.
Alexandra, 27 xyoo, Penza
Kuv noj tshuaj thaum, vim muaj tus mob khaub thuas, o kis mus rau hauv nruab nrab pob ntseg. Tom qab 2 hnub ntawm kev kho mob, qhov kub tsis txias, qhov mob ploj mus thiab hnov kev hnov lus zoo li qub. Muaj me ntsis mob raws plab, tab sis nws tuaj yeem tshwm sim los ntawm tus kab mob, tsis kho.
