Galvus Met yog qhov ua ke tshuaj hypoglycemic uas txo cov piam thaj hauv cov ntshav.
Nws yog siv hauv kev kho mob ntshav qab zib hom 2 txhawm rau tswj kev mob thiab feem ntau zoo txais los ntawm lub cev.
Cov ntaub ntawv dav dav txog cov tshuaj
Vim tias kis tau rau vildagliptin (cov tshuaj yeeb dej caw), qhov cuam tshuam ntawm peptidase enzyme yuav txo qis, thiab kev sib txuas ntawm glucagon-zoo li peptide-1 thiab HIP tsuas nce.
Thaum tus nqi ntawm cov tshuaj no hauv lub cev ua rau siab dua li ib txwm, Vildagliptin txhim kho kev ua haujlwm ntawm cov qe ntshav hauv kev sib raug zoo rau cov piam thaj, uas ua rau kev sib ntxiv ntawm cov tshuaj hormones uas txo qis qab zib.
Nws yuav tsum raug sau tseg tias qhov nce ntawm beta-tes haujlwm yog kiag li nyob ntawm tus nqi ntawm lawv qhov kev rhuav tshem. Vim li no, hauv cov neeg uas muaj cov piam thaj li ib txwm, vildagliptin tsis muaj qhov cuam tshuam rau kev tsim cov tshuaj insulin.
Cov tshuaj ua haujlwm nquag ntawm cov tshuaj nce qib glucagon-zoo li peptide-1 thiab nce rhiab heev ntawm alpha hlwb rau cov piam thaj. Raws li qhov tshwm sim, glucagon synthesis nce. Kev poob qis hauv nws cov nyiaj thaum lub sijhawm ua kev noj mov ua rau muaj kev cuam tshuam ntau ntxiv ntawm cov xaim hluav taws xob txuas nrog rau cov tshuaj hormones uas ua kom qab zib.
Kev Sau ua ke, daim foos tso tawm
Cov tshuaj yog nyob rau hauv daim ntawv ntawm ntsiav tshuaj, uas yog txheej. Ib qho muaj ob qho tseem ceeb: Vildagliptin (50 mg) thiab Metformin, muaj nyob hauv peb koob tshuaj - 500 mg, 850 mg thiab 1000 mg.
Ntxiv rau lawv, cov tshuaj muaj pes tsawg leeg raws li:
- magnesium stearic acid;
- hydroxypropyl cellulose;
- hydroxypropyl methyl cellulose;
- talc;
- titanium dioxide;
- hlau oxide daj lossis xim liab.
Cov ntsiav tshuaj tau ntim rau hauv blisters ntawm kaum daim. Cov pob muaj peb lub hlwv.
Cov chaw muag tshuaj thiab tshuaj pharmacokinetics
Cov suab thaj txo qis ntawm cov tshuaj pom tau hais ua tsaug rau qhov kev ua ntawm ob qho tseem ceeb:
- Vildagliptin - nce kev ua haujlwm ntawm cov hlwb pancreatic tiv thaiv cov ntshav qab zib, uas ua rau kev nce ntxiv hauv cov tshuaj insulin;
- Metformin - txo cov piam thaj hauv lub cev los ntawm kev txo qhov nqus ntawm carbohydrates, txo cov suab thaj ua ke los ntawm daim siab ua haujlwm thiab txhim kho kev siv los ntawm cov ntaub so ntswg.
Cov tshuaj yog siv los ua rau txo qis cov ntshav qab zib hauv lub cev. Ntxiv mus, hauv qee qhov tsis tshua muaj tshwm sim, kev teeb tsa cov ntshav hauv lub cev ntshav yog sau tseg.
Nws tau pom tias kev noj mov tsis cuam tshuam rau qhov nrawm thiab theem ntawm kev nqus ntawm cov tshuaj, tab sis kev saib xyuas ntawm cov khoom siv cuam tshuam tsawg dua me ntsis, txawm hais tias nws txhua tus nyob ntawm qhov ntau ntawm cov tshuaj.
Kev nqus tshuaj yog nrawm heev. Yog tias koj noj cov tshuaj ua ntej noj mov, nws muaj nyob hauv cov ntshav tuaj yeem kuaj pom hauv ib teev thiab ib nrab. Hauv lub cev, cov tshuaj yuav hloov mus rau hauv cov khoom noj ua paug tawm hauv cov zis thiab quav.
Kev taw qhia thiab contraindications
Qhov qhia tau tseem ceeb rau kev siv yog hom ntshav qab zib 2.
Muaj qee qhov xwm txheej thaum koj xav siv cov cuab yeej no:
- nyob rau hauv daim ntawv ntawm monotherapy;
- thaum kho nrog Vildagliptin thiab Metformin, uas yog siv los ua cov tshuaj uas muaj tag nrho;
- kev siv cov tshuaj ua ke nrog cov neeg sawv cev uas txo cov ntshav qab zib thiab muaj cov sulfanyl urea;
- kev siv cov tshuaj ua ke nrog cov tshuaj insulin;
- kev siv cov tshuaj no yog cov tshuaj tseem ceeb hauv kev kho mob ntshav qab zib hom 2, thaum kev noj zaub mov tsis muaj txiaj ntsig ntxiv lawm.
Cov txiaj ntsig ntawm kev noj tshuaj yog ntsuas los ntawm qhov txo qis hauv cov piam thaj hauv cov ntshav.
Thaum yuav siv cov tshuaj yuav tsum tsis txhob:
- intolerance rau cov neeg mob lossis siab rhiab rau cov khoom siv ntawm cov khoom siv kho mob;
- ntshav qab zib hom 1;
- ua ntej kev ua haujlwm thiab kev tso tawm xoo hluav taws xob, kev siv tshuaj hluav taws xob rau kev kuaj mob;
- nrog cov metabolism hauv kev ua tsis tau zoo, thaum ketones raug kuaj pom hauv cov ntshav;
- lub siab ua haujlwm tsis zoo thiab tsis ua haujlwm tau pib tsim;
- mob ntev lossis mob hauv lub plawv lossis lub ntsws tsis ua haujlwm;
- haus cawv ntau dhau;
- cov khoom noj khoom haus tsis muaj tsawg ntawm lub cev;
- cev xeeb tub thiab lactation.
Ua ntej koj pib noj tshuaj, koj yuav tsum paub tseeb tias tsis muaj cov tshuaj contraindications.
Cov lus qhia rau kev siv
Cov tshuaj kho mob yuav tsum tau noj ntawm qhov ncauj tag nrho thiab tsis yog zom.
Txhawm rau kom ua tiav cov kev mob tshwm sim, nws yog qhov zoo dua rau kev noj tshuaj thaum noj mov.
Tus kws kho mob teeb tsa qhov xav tau koob tshuaj sib cais rau txhua tus neeg mob, pib ntawm nws qhov kev txiav txim siab ntau npaum li cas cov piam thaj tau nce ntxiv, uas tus neeg mob tau kho thiab seb nws puas ua haujlwm.
Cov qauv muab tshuaj yog 1 ntsiav tshuaj ib hnub ob zaug, sawv ntxov thiab yav tsaus ntuj. Yog tias cov koob tshuaj ib zaug ib hnub, tom qab ntawd koj yuav tsum tau noj cov tshuaj thaum sawv ntxov.
Cov lus qhia tshwj xeeb
Koj yuav tsum tsis txhob noj cov tshuaj nyob rau hauv qhov muaj mob ua rau lub siab ua haujlwm tsis zoo, vim hais tias nce kev ua haujlwm ntawm cov enzymes ntawm cov khoom nruab nrog cev no.
Nws tsis raug nquahu kom siv cov tshuaj no thaum cev xeeb tub thiab lub sijhawm lactation, vim tias tsis muaj qhov tshwm sim tseeb ntawm cov txiaj ntsig ntawm cov nquag ua haujlwm ntawm lub cev.
Txawm li cas los xij, yog tias cov piam thaj hauv cov dej hauv lub cev xeeb tub tau cuam tshuam thaum noj cov tshuaj, tom qab ntawd muaj kev pheej hmoo ntawm kev tsis ua haujlwm hauv lub cev hauv plab.
Cov neeg mob hnub nyoog tshaj 65 xyoos yuav tsis tas kho qhov ntau npaum li cas.
Yog tias peb tham txog cov menyuam yaus, vim tias qhov tshwm sim thiab qhov kev nyab xeeb uas xav tau tsis tau tshwm sim thaum sim tshuaj, nws tsis pom zoo kom siv cov tshuaj rau cov neeg mob hnub nyoog qis dua.
Muaj ntau cov lus qhia tshwj xeeb, yog tias koj ua raws li lawv, tom qab ntawd koj tuaj yeem zam qhov tsis zoo ntawm kev siv tshuaj:
- cov tshuaj tsis hloov pauv cov tshuaj insulin, uas yuav tsum nco ntsoov rau cov neeg mob ntshav qab zib hom 1;
- nyob rau hauv tus txheej txheem ntawm kev siv yeeb tshuaj, koj yuav tsum tau soj ntsuam cov qib qab zib kom tsis tu ncua hauv lub cev;
- tsawg kawg ib hlis ib zaug, nws yuav tsum kuaj mob ntawm lub raum, mob siab thiab tus nqi ntawm cov kab mob lactic acid;
- thaum lub sijhawm siv cov tshuaj nws yog txwv tsis pub nkag siab txog dej cawv, vim qhov no tuaj yeem ua rau kev tsim ntawm cov kab mob lactic acidosis;
- cov tshuaj tuaj yeem txo qhov nqus ntawm cov vitamin B12, uas qhov teeb meem txhawb kev tsis muaj zog.
Hauv cov tsev muag tshuaj, cov tshuaj muaj peev xwm tsuas yuav nrog cov tshuaj noj.
Phiv thiab haus tshaj
Kev siv cov ntsiav tshuaj tuaj yeem ua rau kev txhim kho kev phiv ntawm cov tshuaj, thiab qhov no yuav cuam tshuam cov kev mob ntawm cov kab mob hauv qab no thiab cov tshuab:
- Lub plab zom mov - pib hnov mob, muaj mob nyob rau hauv plab, muaj kua plab zom mov mus rau qhov qis ntawm txoj hlab pas, tuaj yeem mob ntawm tus txiav, kab mob lub ntsej muag yuav tshwm sim hauv lub qhov ncauj, vitamin B pib muaj kev cuam tshuam tsis zoo.
- Tej leeg hauv siab - mob, kiv taub hau, tshee hnyo.
- Mob siab thiab mob gallstone - kab mob siab.
- Musculoskeletal system - mob hauv pob qij txha, qee zaum hauv cov leeg.
- Cov txheej txheem kev zom zaub mov - nce qib ntawm uric acid thiab ntshav acidity.
- Ua xua - tawm pob rau ntawm daim tawv nqaij thiab khaus, urticaria. Nws tseem muaj peev xwm tsim tau cov kev mob hnyav dua tshwm sim ntawm kev tsis haum ntawm lub cev, uas tau hais tawm hauv angioedema Quincke lossis anaphylactic kev poob siab.
- Muaj qee zaus, cov tsos mob ntawm tus mob ntshav qab zib tsawg tshwm sim, uas yog, tshee ntawm sab sauv, "hws txias". Hauv qhov no, kev ua kom tsawg ntawm carbohydrates (tshuaj yej qab zib, confectionery) tau pom zoo.
Yog tias muaj kev phiv los ntawm cov tshuaj pib tsim, ces nws yuav tsum tau txiav nws txoj kev siv thiab nrhiav tswv yim kho mob.
Kev sib cuam tshuam txog Yeeb Tshuaj thiab Analogs
Yog tias koj siv Galvus Met nrog qee lwm yam tshuaj, nws muaj peev xwm tsim cov kab mob pathological lossis nce / txo qis kev ua haujlwm ntawm cov tshuaj siv.
Nrog rau kev siv ua ke nrog Furosemide, qhov kev txiav txim siab hauv cov ntshav ntawm cov tshuaj thib ob yuav nce ntxiv, tab sis cov nyiaj hauv thawj yuav poob qis.
Noj Cov Khoom Noj Nifedipine thaum kho yuav ua rau muaj kev nrawm nrawm, tshem tawm los ntawm ob lub raum, nrog rau kev nce ntxiv ntawm Metformin hauv cov ntshav.
Yog tias siv nrog glibenclamide, tom qab ntawd cov ntsiab lus ntawm tom kawg yuav pib poob qis.
Nws tsis pom zoo kom noj ua ke nrog Donazol, vim nws muaj cov nyhuv hyperglycemic. Yog tias kev sib xyaw ua ke ntawm cov tshuaj tsuas yog kev tsim nyog rau kev kho mob, ces koj yuav tau kho cov tshuaj ntawm Metformin thiab tshuaj xyuas cov piam thaj hauv cov ntshav ntau ntau.
Diuretic, tshuaj tiv thaiv, tshuaj glucocosteroid, calcium channel blockers, Phenothiazine - thaum siv ua ke nrog Galvus Met, lawv tuaj yeem ua rau mob ntshav qab zib. Siv tsawg kawg 100 mg ntawm Chlorpromazine ua ke nrog Galvus Met rau ib hnub, koj tuaj yeem nce glycemia, ntxiv rau txo qis tsim kom muaj cov tshuaj insulin.
Thaum siv radiopaque tus neeg sawv cev nrog iodine thaum kho, lactic acidosis pib rau, uas yog kev yooj yim los ntawm kev ua haujlwm hauv lub raum. Yog tias koj siv cov tshuaj uas muaj cawv ethyl tib lub sijhawm, kev pheej hmoo ntawm cov kab mob lactic acidosis tseem yuav nce ntxiv.
Galvus Met muaj cov yeeb yaj kiab hauv qab no ntawm kev tsim tawm hauv tsev: Avandamet, Glimecomb thiab Combogliz Prolong.
Avanta muaj 2 yam tshuaj lom neeg - Rosiglitazone thiab Metformin. Cov tshuaj yog siv los kho cov tshuaj insulin-ywj pheej ntawm tus kab mob. Rosiglitazone pab ua rau muaj kev cuam tshuam ntawm cov hlwb ua rau cov tshuaj insulin, thiab Metformin txo cov synthesis ntawm qabzib los ntawm lub siab.
Glimecomb yog li ntawm Metformin thiab Glyclazide, uas tso cai rau koj kom sai rau qib qab zib. Nws yog contraindicated rau kev siv nrog cov tshuaj insulin-hom mob ntshav qab zib, tsis nco qab, lactation, thiab lwm yam.
Comboglyz Prolong muaj Metformin thiab Saxagliptin. Nws yog siv los tawm tsam mob ntshav qab zib hom 2, thaum nws tsis tuaj yeem txo qis qab zib los ntawm kev noj zaub mov thiab ua kom lub cev qoj ib ce. Nws tsis pom zoo kom siv nrog intolerance rau cov tshuaj muaj nyob hauv nws, ntshav qab zib insulin-tiv thaiv cov menyuam yaus, thaum lub cev xeeb tub, lub sijhawm lactation.
Kev xav ntawm cov kws tshaj lij thiab cov neeg mob
Los ntawm kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog Galvus Met, peb tuaj yeem xaus tias cov tshuaj muaj txiaj ntsig hauv kev txo qis ntshav qab zib. Cov kev mob tshwm sim muaj tsawg heev thiab raug tso tseg los ntawm kev txo qis hauv thaj chaw ntawm cov tshuaj.
Cov tshuaj yog zwm rau pab pawg ntawm cov tshuaj IDDP-4, yog sau npe nyob rau hauv Russia ua cov tshuaj rau hom 2 mob ntshav qab zib mellitus. Nws ua hauj lwm zoo thiab nyab xeeb heev, zoo zam txim los ntawm cov ntshav qab zib, tsis ua rau nce phaus ntxiv. Galvus Met raug tso cai siv nrog kev txo qis hauv lub raum, uas yuav tsis ua rau muaj kev kho mob rau cov neeg laus.
Olga, endocrinologist
Zoo tsim tshuaj. Nws qhia tau zoo heev hauv kev tswj cov qib qab zib.
Lyudmila, tus kws tshuaj
Yam 2 ntshav qab zib mellitus tau tshawb pom kaum xyoo dhau los. Kuv tau sim siv tshuaj ntau, tab sis lawv tsis txhim kho kuv tus mob ntau. Tom qab ntawd tus kws kho mob qhia Galvus. Kuv tau noj nws ob zaug ib hnub thiab sai li ntawd cov piam thaj tau ua zoo li qub, tab sis cov kev mob tshwm sim ntawm cov tshuaj tshwm sim, uas yog, mob taub hau thiab tawm pob. Tus kws kho mob pom zoo hloov mus rau ib qho tshuaj ntawm 50 mg, qhov no tau pab. Thaum lub sijhawm, tus mob zoo heev, yuav luag tsis nco qab txog tus kabmob.
Maria, 35 xyoo, Noginsk
Ntau tshaj kaum tsib xyoos tau mob ntshav qab zib. Tau ntev, kev kho mob tsis nqa cov txiaj ntsig tseem ceeb kom txog thaum tus kws kho mob pom zoo kom yuav Galvus Met. Ib qho cuab yeej zoo, ib koob rau ib hnub yog txaus rau qhov qub suab thaj. Thiab txawm hais tias tus nqi ntau dhau, Kuv tsis kam tsis kam siv tshuaj, nws zoo heev.
Nikolay, 61 xyoo, Vorkuta
Cov khoom siv los ntawm Dr. Malysheva txog cov khoom lag luam tuaj yeem pab kho mob ntshav qab zib:
Cov tshuaj yuav tau ntawm txhua lub tsev muag tshuaj. Tus nqi yog li ntawm 1180-1400 rubles., Nyob ntawm thaj av ntawd.