Kev siv tshuaj insulin - kev qhia ntawm cov tshuaj insulin-rau kev kho mob lub hom phiaj. Muaj ntau ntau cov tshuaj raws li cov tshuaj no, uas tau muab faib ua ntau pawg nyob ntawm lub sijhawm ntawm qhov pib ntawm cov nyhuv thiab lub sijhawm ua. Ib qho ntawm cov neeg sawv cev ntawm cov tshuaj nruab nrab-ntev yog Insulin -isophane. Nyeem ntxiv txog nws cov ntawv thov hauv kab lus.
Pharmacological kev txiav txim
Insulin-isophan (tib neeg caj hlav hauv tshuab hlwb hlau) yog tsim los ntawm kev hloov kho cov tshuaj hormone DNA los ntawm kev ua kom muaj kab mob ntawm cov kab mob tsis muaj txheej txheem uas yog los ntawm chav kawm ntawm saccharomycetes. Thaum nkag mus rau hauv lub cev, cov tshuaj yeeb tshuaj ua rau qee qhov nyuaj nyob rau thaj chaw ntawm cov hlwb uas ua rau ntau cov kev hloov hauv cov hlwb lawv tus kheej, suav nrog cov tshuaj ntawm cov tshuaj tseem ceeb.
Cov nyhuv hypoglycemic ntawm Insulin-Isophan yog txuam nrog kev ua kom sai ntawm cov txheej txheem ntawm kev noj cov piam thaj los ntawm cov ntshav mus rau hauv lub hlwb ntawm tib neeg lub cev, nrog rau kev ua kom qeeb hauv kev tsim ua ke ntawm qabzib los ntawm hepatocytes ntawm lub siab. Tsis tas li, cov tshuaj txhawb kev tsim ntawm cov tshuaj protein, koom nrog hauv cov metabolism hauv cov rog.
Lub sijhawm ntawm cov nyhuv tom qab tswj hwm ntawm cov tshuaj yog nyob ntawm nws qhov nqus tus nqi, uas, nyeg, yog txiav txim siab los ntawm ntau yam:
- koob tshuaj;
- txoj kev ntawm cov thawj coj;
- qhov chaw ntawm kev taw qhia;
- lub xeev ntawm tus neeg mob lub cev;
- muaj cov kab mob concomitant (feem ntau kis);
- kev siv lub cev;
- lub cev nyhav ntawm tus neeg mob.
Tus kws endocrinologist yog tus kws paub tshwj xeeb uas yuav pab koj xaiv cov tshuaj insulin kho mob
Raws li kev txheeb cais, qhov kev ua haujlwm ntawm Insulin-isophan tshwm tom qab 1.5 teev txij li lub sijhawm txhaj, lub sijhawm ua haujlwm tau ntev txog 24 teev. Cov qib siab tshaj plaws hauv cov ntshav hauv cov ntshav tau pom ntawm 2 mus rau 18 teev tom qab kev coj ntawm cov tshuaj hauv qab daim tawv nqaij.
Cov tshuaj tsis dhau rau hauv cov mis thaum pub niam mis. Txog li 75% ntawm cov tshuaj tawm hauv cov zis. Raws li kev tshawb fawb, cov tshuaj tsis muaj tshuaj lom rau cov kab mob deev thiab tib neeg DNA, tsis muaj cov teebmeem carcinogenic.
Thaum twg cov tshuaj tau sau tseg?
Cov lus qhia rau kev siv qhia tias qhov ntsuas ntawm kev siv tshuaj Insulin-isophan yog:
Kev Siv Tshuaj Insulin- insulin-tso ua hom mob ntshav qab zib;
- cov ntshav qab zib uas tsis yog insulin-tiv thaiv kev mob ntshav qab zib;
- ib nrab tsis kam rau kev nqis tes ntawm cov tshuaj ua suab thaj-txo cov tshuaj;
- lub xub ntiag ntawm cov kabmob sib kis (cov uas koom nrog los ntawm lub caij nyoog, tab sis ua rau kom muaj kab mob pob txha hnyav ntxiv);
- mob ntshav qab zib hauv kev xeeb tub ntawm cov poj niam cev xeeb tub.
Txoj kev ntawm daim ntawv thov
Daim ntawv tso tawm ntawm cov tshuaj yog kev ncua rau kev txhaj tshuaj ntawm 40 IU hauv 1 ml. Lub raj mis muaj 10 ml.
Isulin insulin siv tshwj xeeb txhaj ib leeg xwb. Cov koob tshuaj yog xaiv los ntawm tus koom nrog cov kws tshaj lij, suav txog tus tub los ntxhais, hnub nyoog ntawm tus neeg mob, nws lub cev qhov hnyav, cov ntshav qab zib thiab cov kev tawm dag zog. Raws li txoj cai, 0.5-1 IU ib hnub yog tau sau tseg rau ib kilogram ntawm lub cev qhov hnyav.
Cov tshuaj tuaj yeem muab tshuaj:
- hauv tus ncej puab;
- pob tw;
- anterior plab phab ntsa;
- deltoid leeg ntawm lub xub pwg.
Cov tshuaj yeeb tshuaj yog muab tshwj xeeb subcutaneously, tas li hloov qhov chaw txhaj tshuaj
Qhov chaw yuav tsum tau hloov tas li. Qhov no yog qhov tsim nyog los tiv thaiv kev txhim kho ntawm lipodystrophy (ib qho xwm txheej uas cov subcutaneous rog txheej atrophies).
Nqa tawm cov tshuaj insulin siv Insulin-Isophan, zoo ib yam li lwm yam tshuaj raws li pancreatic hormone analogue, yuav tsum tau ua ke nrog kev kuaj xyuas theem ntawm glycemia hauv kev hloov pauv.
Qhov ntau ntawm cov tshuaj yuav tsum tau kho hauv cov xwm txheej hauv qab no:
- ntev tsis txaus ntawm adrenal cortex;
- hypothyroidism;
- mob nyhav ntawm lub raum lossis nplooj siab;
- cov kis kab mob uas nrog tus mob lub cev kub;
- laus laus ntawm tus neeg mob.
Cov kev thaiv tsis zoo thiab cov tshwm sim
Kev siv tshuaj isulin tsis yog rau kev kho mob insulin nyob ib puag ncig ntawm ib tug neeg rhiab heev rau cov yam khoom ua si, nyob rau hauv qhov tshwm sim ntawm lub cev-txiav txim siab rau lub qog nqaij hlav thiab nrog txo qis glycemia.
Cov lus qhia ntawm kev noj tshuaj ntau dua li tsim nyog yuav ua rau lub xeev hypoglycemic. Nws cov kev qhia tseem ceeb yog mob taub hau thiab kiv taub hau, ib txoj kev paub ntawm kab mob kev tshaib plab, tawm hws ntau dhau. Cov neeg mob yws yws ntawm txhais tes tshee hnyo, ntiv tes, qhov tshwm sim ntawm xeev siab thiab ntuav, ntshai thiab zoo li mob siab.
Tseem Ceeb! Ntawm kev txheeb xyuas, lub cim xeeb tsis txaus, kev ua kom tsis muaj kev cuam tshuam, kev tsis zoo hauv qhov chaw, thiab kev hais lus tsis zoo tuaj yeem txiav txim siab.
Mob Hypoglycemia - ntshav qab zib tsawg uas tuaj yeem tshwm sim los ntawm kev noj ntau dhau ntawm pancreatic hormone
Ntxiv rau kev noj ntau dhau, qhov xwm txheej etiological ntawm qis glycemia tuaj yeem dhia noj mov tom ntej, hloov ib qho tshuaj insulin rau lwm tus, kev qoj ib ce dhau hwv, hloov thaj chaw ntawm kev tswj hwm, ib txhij kho nrog ntau pawg tshuaj.
Lwm qhov kev mob tshwm sim uas tuaj yeem tshwm sim vim kev tsis ua raws li kev tswj hwm tshuaj noj sijhawm lossis cov tshuaj noj tsis raug xaiv tuaj yeem yog qhov mob tshwm sim hyperglycemic. Nws cov tsos mob tshwm li hauv qab no:
- tus neeg mob feem ntau haus thiab tso zis;
- bouts ntawm xeev siab thiab ntuav;
- Kiv taub hau
- daim tawv nqaij qhuav thiab cov leeg nqaij;
- kev hnov mob ntawm cov tshuaj tsw qab hauv cov pa hauv cov pa tawm.
Cov tshuaj kuj tseem tuaj yeem ua rau muaj kev tsis haum tshuaj, uas tau tshwm sim los ntawm cov syndromes hauv qab no:
- urticaria;
- Quincke's edema;
- anaphylactic poob siab.
Ntawm qhov chaw txhaj tshuaj, edema, ib cov tshuaj tiv thaiv mob liab, liab, khaus, hemorrhage, thiab lipodystrophy tuaj yeem tshwm sim.
Nws kuj tseem muaj cov xwm txheej uas qhov kev siv ntawm Insulin-isophan txhaum lub peev xwm tsav tsheb thiab lwm yam txheej txheem. Qhov no tuaj yeem vim qhov pib siv cov tshuaj, hloov ntawm ib cov tshuaj mus rau lwm qhov, cov txiaj ntsig ntawm kev ntxhov siab, thiab nrog lub cev ua haujlwm tseem ceeb.
Muaj qee kis, kiv taub hau tuaj yeem txhim kho, uas yog ib qho kev cuam tshuam rau kev tsav tsheb.
Cev xeeb tub thiab lactation
Cov tshuaj ua kom muaj zog ntawm cov tshuaj tsis nkag rau hauv niam mis thiab los ntawm qhov chaw tiv thaiv placental, yog li ntawd, insulin-isofan tuaj yeem kho rau cov poj niam thaum lub sijhawm xeeb tub thiab lactation. Nws yog ib qho tseem ceeb rau xam qhov tseeb ntawm lub koob tshuaj uas tau tso cai, vim tias qhov nce ntxiv lossis txo qis rau cov piam thaj hauv leej niam cov ntshav thaum siv cov tshuaj tsis raug yog qhov tsis zoo rau tus menyuam hauv plab.
Yeeb tshuaj sib cuam tshuam
Muaj cov tshuaj uas tuaj yeem txhim kho hypoglycemic nyhuv ntawm Insulin-isophan, tab sis muaj cov uas, ntawm qhov tsis sib xws, ua rau nws tsis muaj zog, uas ua rau nce ntshav qab zib cov neeg mob.
Thawj pawg tshuaj muaj xws li:
- cov tshuaj hypoglycemic;
- ACE inhibitors;
- sulfonamides;
- ib co tshuaj tua kab mob;
- anabolic tshuaj steroids;
- antifungal tus neeg sawv cev;
- Theophylline;
- lithium-based npaj;
- Clofibrate.
Cov neeg sawv cev ntawm pawg pab pawg tetracycline muaj peev xwm txhim kho cov nyhuv hypoglycemic ntawm insulin
Pawg ob suav nrog:
- cov tshuaj hormones ntawm adrenal cortex;
- COCs;
- cov thyroid hormones;
- heparin;
- tshuaj kho mob
- tshuaj tiv thaiv kab mob;
- sympathomimetics.
Cov npe lag luam
Isulin insulin yog qhov tshuaj nyob ntawm ntau yam ntawm tib neeg cov tshuaj insulin, yog li nws lub npe lag luam muaj ntau hom (txhais ua):
- Biosulin-N;
- Protafan NM;
- Protafan NM Penfill;
- Rosinsulin C;
- Humodar B 100 Hav dej;
- Humulin NPH.
Insulin yog suav tias yog tshuaj noj. Kev noj tshuaj rau tus kheej nrog cov cuab yeej yog qhov tsis tsim nyog.
