Pentilin yog tshuaj antispasmodic nrog rau qhov kev pom ntawm qhov dav dav, uas yog pawg pawg ntawm purines. 2 daim ntawv tso tawm, suav nrog cov ntsiav tshuaj, xav tau tshuaj. Thaum cov tshuaj siv rau prophylactic thiab kho lub hom phiaj, vascular lumen nce, phab ntsa ua ywj. Muaj txiaj ntsig zoo ntawm cov leeg ua pa. Nyob rau hauv cov muaj pes tsawg leeg ntawm txhua daim ntawv muaj cov yooj yim thiab ntu pabcuam cov khoom sib txuam. Kev siv yog nqa tawm raws li cov lus qhia. Cov kev mob tshwm sim tuaj yeem tshwm sim, tshwj xeeb yog muaj contraindications.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
INN ntawm cov tshuaj yog pentoxifylline.
Pentilin yog tshuaj antispasmodic nrog rau qhov kev pom ntawm qhov dav dav, uas yog pawg pawg ntawm purines.
ATX
Cov tshuaj tau muab rau tus kheej ATX code - C04AD03 thiab tus lej sau npe - No. RK-LS-5 No. 004325 hnub tim 16.10.2011.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj raug muag nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab ib qho kev daws teeb meem rau kev ruaj khov lossis tswj kev siv tshuaj. Cov sib xyaw ua ke ntawm ob daim ntawv tshuaj muaj cov tshuaj nquag, thaum lawv nkag mus rau hauv tus neeg mob lub cev, qhov no lossis qhov ua kom zoo rau kev ua tiav. Kev sib xyaw cov ntsiab lus tsis cuam tshuam qhov kev nyab xeeb ntawm cov tshuaj thiab ua kom ruaj khov.
Ntsiav tshuaj
Daim ntawv tshuaj rau cov tshuaj muaj 400 mg ntawm pentoxifylline. Cov ntsiav tshuaj yog coated nrog cov yas-cov zaj duab xis, uas muaj:
- titanium dioxide;
- macrogol;
- hypromellose;
- talcum hmoov.
Daim ntawv tsuas tshuaj ntawm Pentilin muaj 400 mg ntawm pentoxifylline.
Cov ntu pab muaj xws li:
- magnesium stearate;
- anhydrous silica colloidal;
- macrogol.
Dawb, biconvex, oblong ntsiav tshuaj muaj muag hauv 10 ntim.
Tus naj npawb ntawm blisters nyob rau hauv ib lub thawv cardboard - tsis ntau tshaj 2 pcs.
Sab nraum qab ntawm lub thawv muaj cov cim tsim nyog. Cov lus qhia rau kev siv yog ntim rau hauv pob.
Tshuaj
Cov kua dej rau cov tshuaj mob plab thiab mob ntshav muaj 100 mg ntawm cov nquag ua hauj lwm.
Pentilin kua tshuaj hloov mus rau muag ntawm ampoules ntawm 5 ml.
Nws yog cov kua ntshiab, tsis muaj kob lossis daj uas tsis muaj lwm yam khoom. Lwm cov hauv kev sib xyaw ua ke ntawm daim ntawv ntau npaum:
- sodium dihydrogen phosphate dihydrate;
- sodium hydrogen phosphate dihydrate;
- dej rau kev txhaj tshuaj;
- sodium tshuaj dawb;
- edetate disodium.
Cov kua yog lag luam hauv 5 ml ampoules. Hauv pob ntawv los qhia 5 ampoules muab tso rau hauv lub hlwv. Cov lus qhia siv rau hauv daim ntawv ntawm cov ntawv tso tawm thiab cim rau sab nraum qab ntawm lub thawv yog muaj.
Pharmacological kev txiav txim
Lub hauv paus nquag nyob rau hauv muaj pes tsawg leeg ntawm daim ntawv tsuas tshuaj zoo cuam tshuam rau cov hlab plawv system, ua pa system, yug me nyuam thiab tso zis system. Siv tau hauv otolaryngology, gynecology thiab urology. Nrog kev siv tsis tu ncua, cov ntshav ncig ua haujlwm li qub, rheological cov yam ntxwv ntawm cov ntshav txhim kho.
Cov nquag ua haujlwm nyob rau hauv cov tshuaj muaj pes tsawg leeg ntawm Pentilin nyiam cov cuam tshuam ntawm cov hlab plawv cov ntshav.
Lub hauv paus ntsiab lus ntawm kev txiav txim siab ntawm ib daim ntawv tshuaj twg yog ua raws li kev txwv ntawm phosphodiesterase. Nyob rau tib lub sijhawm, muaj qhov nce siab ntawm qib theem ntawm cyclic AMP hauv platelets thiab ATP hauv cov ntshav liab. Vasodilation tsim tawm los ntawm kev khov kho ntawm lub zog muaj peev xwm, peripheral vascular tsis kam poob qis. Nrog cov ntshav nce ntau zuj zus, lub mem tes tseem tsis hloov.
Qhov ua tiav antianginal tau ua tiav vim muaj peev xwm ntawm cov tshuaj los nthuav cov hlab ntshav cov hlab ntsha, uas ua kom cov ntshav ntawm cov ntshav oxygen mus rau myocardium. Cov ntshav oxygenation tau los ntawm kev nce lub lumen ntawm cov hlab ntsha cov hlab ntsha.
Nrog rau kev siv tsis tu ncua, lub suab ntawm lub diaphragm thiab cov leeg ntawm cov cheeb tsam intercostal nce.
Lub microcirculation ntawm cov ntshav txhim kho, lub cev hloov kho ntawm cov qog ua ntshav ntawm cov qe ntshav liab nce. Ntshav ua viscous tsawg. Kev puas tsuaj rau cov hlab ntsha peripheral tuaj yeem cuam tshuam kev txhim kho ntawm qhov sib quas ntus claudication. Hauv qhov no, kev siv ntawm cov tshuaj tshem tawm qhov mob thiab cramps hauv plab nqaij nyuj, tshwj xeeb tshaj yog thaum tsaus ntuj.
Cov Tshuaj Pharmacokinetics
Ib daim ntawv ntawm kev tso tawm sai sai tsis xeb tsis suav cov qauv ntawm daim ntawv thov. Daim foos tshuaj yuav tsis ua rau mob lub plab ntawm lub plab, plab hnyuv. Qhov siab tshaj plaws ntawm pentoxifylline hauv cov ntshav ntshav tuaj yeem txiav txim siab 3-4 teev tom qab txhaj thawj zaug. Kev ua txhua yam rau cov ntshav protein tsis tshwm sim.
Daim ntawv foos ntawm Pentilin tsis ua rau mob plab hnyuv tawm.
Lub sijhawm ua haujlwm ntev ntev ntawm cov ntsiav tshuaj daim ntawv yog raws cov kev maj mam tawm ntawm cov tshuaj nquag thiab nws txoj kev nqus sai. Nws tsis txo qis cov kev ua haujlwm ntawm daim siab enzymes, txawm hais tias qhov tseeb hais tias kev ua metabolism yog nqa los ntawm lub cev no. Metabolites (carboxypropyl thiab hydroxyhexyl dimethylxanthine) yog suav hais tias ua haujlwm.
Thaum tswj hwm qhov quav tshuaj, cov tshuaj muaj qhov ntim ntawm cov khoom faib tawm thiab siab tshem tawm. Ib nrab-lub neej yog 1.5 teev. Metabolites tawm hauv lub cev nrog zis (txog 95%). Ib qho me me (3-4%) yog tawm los ntawm cov hnyuv. Nws muaj peev xwm nkag mus rau hauv niam cov kua mis.
Kev ntsuas rau siv
Cov cim tseem ceeb rau kev siv yog cov kab mob cuam tshuam nrog cov kev mob hauv plawv. Cov no suav nrog:
- kev cuam tshuam ntawm cov qog vias hloov ntawm kev nkag siab;
- mob hnyav, subacute thiab mob ntshav plawv tsis ua haujlwm thiab lwm yam kev pom;
- cov kab mob cerebrovascular mob heev;
- obliterating endarteritis;
- peripheral circulatory mob provoked los ntawm ntshav qab zib mellitus thiab atherosclerosis;
- angiopathy;
- Raynaud's disease;
- paresthesia;
- kev cuam tshuam ntawm cov hlab ntsha thiab txoj hlab ntshav ncig vim frostbite, mob qog, mob ncauj plab;
- atherosclerotic thiab dyscirculatory encephalopathy.
Ib qho tshuaj antispasmodic raug tso cai siv rau hauv kev kho mob poj niam lub cev thaum lub caij cov tsos mob ua ntej.
Cov Yuav Tsum Muaj
Kev siv cov tshuaj tsis tsim nyog yog tias tus neeg mob tau contraindications sau tseg hauv cov lus qhia. Cov no suav nrog:
- mob ntshav roj;
- retinal hemorrhages;
- cov ntshav tsis loj, nrog rau kev tso ntshav tawm;
- hemorrhagic mob stroke (mob thiab mob hnyav);
- mob loj tuaj;
- arterial hypotension;
- myocardial infarction;
- porphyria;
- kev puas tsuaj ntau rau cov leeg thiab cov hlab ntsha;
- lub sij hawm ntawm kev xeeb tub;
- pub niam mis;
- cov menyuam yaus thiab tub ntxhais hluas (txog 18 xyoo);
- kev tiv thaiv tsis haum.
Cov tshuaj muaj ob peb tus txheeb ze contraindications, hauv kev ua tib zoo siv pub.
Kev siv cov tshuaj tsis tuaj yeem lees txais rau hemorrhage hauv retina.
Nrog saib xyuas
Tus txheeb ze contraindications suav nrog peptic rwj ntawm lub plab thiab duodenum. Lub plawv tsis ua haujlwm, mob raum thiab lub siab pathologies kuj yuav tsum siv kev xyuam xim. Yog tias tus neeg mob muaj keeb kwm muaj mob sab hauv thiab sab hauv lub cev, txoj kev tswj hwm yog ua raws li kev saib xyuas ntawm tus kws tshaj lij.
Yuav noj cov tshuaj Pentilin li cas
Daim ntawv muab tshuaj rau lub hauv paus tswj qhov ncauj yuav tau noj raws seem yog tias muab tshuaj rau nws noj. Nws raug nquahu kom haus nws nrog ib khob hau rhaub ntawm qhov kub thiab txias. Kev siv tshuaj rau txhua hnub - tsis pub ntau tshaj 3 ntsiav tshuaj hauv ib hnub, 1 ntsiav tshuaj ib zaug tom qab txhua pluas noj.
Lub sijhawm ntawm daim ntawv thov raug txiav txim siab ib tus zuj zus, feem ntau nws yog 7-8 lub lis piam.
Kev daws tau txhaj rau hauv cov leeg ntshav lossis leeg ntshav siv cov tee ntshav. Lub chav kawm ntawm txoj kev kho yog txiav txim siab nyob ntawm qhov kev nyob zoo ntawm cov neeg mob. Ua ntej muab cov infusion, tus neeg mob yuav tsum pw. Tsis pub ntau tshaj 300 mg (3 ampoules) tau txais ib zaug ib zaug. Lub sijhawm ntawm kev lis ntshav yog 1 teev, nyob rau ib hnub - tsis pub ntau tshaj 2 txheej txheem.
Pentilin daws yog txhaj rau hauv cov leeg ntshav lossis hlab ntshav siv cov tee dej.
Yuav kom ua tiav cov txiaj ntsig siab tshaj plaws, koj tuaj yeem nqa tag nrho ob daim ntawv teev tshuaj hauv lem. Hauv nruab hnub, tus neeg mob tau txais kev daws teeb meem, ua ntej mus pw, koj nqa tau 1 lub tshuaj.
Tus antispasmodic tuaj yeem sib xyaw nrog lwm cov kev daws teeb meem tsuas yog tom qab sim.
Cov koob tshuaj ntawm Txoj kev lis ntshav daws teeb meem (Ringer, 0.9% sodium chloride) kuj raug txiav txim siab ntawm tus kheej.
Nrog ntshav qab zib
Cov neeg mob uas muaj hom 2 thiab hom 3 mob ntshav qab zib mellitus yuav tsum tau noj tshuaj hauv qab kev tswj hwm ntawm tus kws tshaj lij. Yuav tsum tau txhaj kom haum.
Kev phiv tshuaj ntawm Pentilin
Hauv cov neeg mob hypersensitive thiab nrog xaiv tsis ntau txoj kev noj tshuaj, qhov kev pheej hmoo ntawm cov tshuaj tsis tso tawm ntau los ntawm lub cev. Cov tsos mob tshwm sim tau pom nyob ntawm cov khoom nruab nrog sab hauv, nruab nrab cov hlab ntsha thiab tawv nqaij.
Tom qab noj cov tshuaj Pentilin, raws plab tuaj yeem tshwm sim.
Ntawm ib feem ntawm cov khoom hauv nruab nrog kev pom
Kev pom, qhov ua nyuj yog qhov tshwm sim vim kev mob tshwm sim.
Kev kho mob txoj hnyuv
Ntawm ib feem ntawm cov plab hnyuv plab zom mov, raws plab, xerostomia, tsis poob, qab los thiab ntuav yog pom. Tus mob cholecystitis yuav mob heev ntxiv thiab cov neeg tsis nco qab yuav mob taus.
Hematopoietic plab hnyuv siab raum
Cov kev mob tshwm sim los ntawm cov ntshav ncig yog qhia hauv daim ntawv ntawm pancytopenia, thrombocytopenia, leukopenia thiab los ntshav hauv txoj hnyuv.
Nruab nrab hauv lub paj hlwb
Los ntawm ib sab ntawm lub hauv nruab nrab lub paj hlwb muaj kiv taub hau, qaug dab peg, zoo nkaus li muaj kev ntxhov siab, pw tsaug zog thiab mob tob hau.
Los ntawm lub tshuab ua pa
Cov kev mob tshwm sim hauv hom no suav nrog kev ua pa nyuaj.
Noj Pentilin yuav ua rau ua pa siav.
Ntawm ib sab ntawm daim tawv nqaij
Cov kev mob tshwm sim rau ntawm daim tawv nqaij yog manifested nyob rau hauv daim ntawv ntawm hyperemia. Ntsia daim hlau ntawm ob txhais tes ua ntau brittle.
Los ntawm cov hlab plawv system
Los ntawm ib sab ntawm cov hlab plawv, tus neeg mob txhim kho tachycardia, cardialgia thiab arrhythmia. Hypotension yuav tshwm sim.
Kev ua xua
Ua xua tau tshwm sim nyob rau hauv daim ntawv ntawm urticaria, daim tawv nqaij hyperemia, khaus thiab kub. Muaj qee zaus, kev poob siab anaphylactic kuj yuav tshwm sim.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Ib qho tshuaj antispasmodic tsis cuam tshuam rau qhov ceev ntawm lub hlwb kev xav, yog li tsav tsheb thaum lub sijhawm kho nrog tshuaj yog ua tau.
Cov lus qhia tshwj xeeb
Thaum lub sij hawm thov, nws yog ib qhov tsim nyog los soj ntsuam cov ntshav siab. Cov neeg mob siab mob ntshav siab yuav tsum tau txo cov tshuaj ntau npaum li cas.
Thaum siv Pentilin, nws yog ib qho tsim nyog los soj ntsuam cov ntshav siab.
Kev ua raws li kev nyiam huv ntawm tus kheej thaum lub sijhawm kho yog qhov yuav tsum tau ua, tab sis yuav tsum zam tus dej ntawm qhov chaw txhaj tshuaj.
Siv rau lub sijhawm qub
Cov neeg laus yuav tsum tau noj tshuaj kom zoo nrog rau kev kho kom haum tau ntawm kev noj tshuaj.
Txiag tej menyuam
Cov me nyuam lub hnub nyoog raug suav hais tias yog ib qho tsis txaus contraindication.
Siv thaum cev xeeb tub thiab lactation
Thaum lub sijhawm lub sijhawm pub mis niam thiab kev xeeb menyuam, nws raug txwv tsis pub noj cov tshuaj antispasmodic.
Daim ntawv thov rau lub raum khiav tsis zoo
Pathologies ntawm lub raum yog suav tias yog kev txheeb ze tsis sib haum, kev siv hauv qhov no yuav tsum tau ceev faj.
Nrog lub raum pathologies, cov tshuaj yuav tsum tau siv nrog ceev faj.
Siv rau lub siab ua haujlwm tsis zoo
Lub siab ua haujlwm tsis zoo yuav tsum ua tib zoo saib xyuas.
Pentilin Noj Tsaus
Rov ua dua dhau ntawm cov txheej txheem kho ua rau npau taws txhawb kev txhim kho ntawm kev overdose. Nws cov xeeb ceem muaj xws li:
- tsaus muag
- los ntshav hauv cov hnyuv;
- tus ntse txo cov ntshav siab;
- cov tsis muaj zog dav dav;
- kev ntxhov siab txog pw tsaug zog (tsaug zog, pw tsaug zog);
- kev xav ntau dhau.
Kev hais mus rau lub tuam tsev kho mob yog qhov yuav tsum tau ua, kev kho mob cov tsos mob yog kws kho. Thawj qhov kev pabcuam yog hauv kev ntxuav lub plab ntawm tus neeg mob. Tsis tas li, nws yuav tsum raug muab rau ib qho kev nkag mus rau lwm tus.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog rau kev tswj hwm tib lub sij hawm ntawm antispasmodic thiab tshuaj uas txo cov ntshav siab, kev pheej hmoo ntawm cov hlab ntshav nce ntxiv.
Pentilin muaj peev xwm txhim kho cov haujlwm ntawm cov tshuaj tua kab mob.
Cov tshuaj muaj peev xwm txhim kho kev ua haujlwm ntawm tshuaj tua kab mob. Cov tshuaj Insulin thiab lwm cov tshuaj hypoglycemic, ua ke nrog cov tshuaj, ua rau kev txhim kho ntawm cov ntshav qog. Tshuaj ntxiv thiab cov vitamins nyob rau tib lub sijhawm ua antispasmodic txhim kho kev phiv los ntawm cov hnyuv.
Cawv tau zoo
Cov tshuaj muaj qhov tsis zoo sib xws nrog ib qho dej cawv.
Analogs
Cov tshuaj muaj ntau txoj kev ua yeeb yam zoo sib xws nrog kev sib xyaw zoo sib xws thiab hloov pauv nrog cov nyhuv tshuaj zoo sib xws. Antispasmodic uas muaj lub npe zoo ib yam nkaus tseem cia nrog, muaj cov tsiaj ntawv ua ntej "Retard" thiab muaj nyob hauv ntsiav tshuaj daim ntawv.
Nws yog siv rau cov roj ntsha hauv lub plawv, muaj contraindications zoo ib yam li kev kho mob qub.
Agapurin raug xa mus rau cov generics. Angioprotector nrog cov nyhuv vasodilating muaj txiaj ntsig. Muaj nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj thiab infusion daws. Pentoxifylline (400 lossis 600 mg) yog tam sim no. Tus nqi ntawm cov tshuaj analogues hauv cov khw muag tshuaj nws txawv ntawm 280-400 rubles.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Txhua daim ntawv tso tawm tshuaj antispasmodic yuav tsum tau tshuaj los ntawm lub tsev muag tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tshuaj yuav tsis tau muas yam tsis muaj ntawv sau ua lus Latin.
Pentilin Nqe
Tus nqi ntawm cov ntsiav tshuaj thiab cov tshuaj antispasmodic hauv cov chaw muag tshuaj txawv nyob ntawm cov ntsiab lus muag. Cov tshuaj tsis rau npe hauv thaj chaw ntawm Lavxias teb sab.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj yuav tsum tso rau hauv cov tub rau khoom sab saud kom nrug deb ntawm cov tsiaj thiab menyuam. Qhov chaw yuav tsum ua kom qhuav thiab txias.
Hnub tas sij hawm
Kev khaws cia ntawm ib daim ntawv tso tawm los ntawm lub sijhawm qhib lub pob - tsis pub dhau 60 lub hlis.
Pentilin analog - Agapurin tuaj yeem muas tsis tau tshuaj.
Chaw tsim tshuaj paus
Tus thawj cov tshuaj yog tsim nyob rau hauv Slovenia. Qhov ze tshaj plaws analogues yog tsim nyob rau hauv Russia.
Pentilin tshuaj xyuas
Kev tshuaj xyuas ntawm cov kws kho mob thiab cov neeg mob txog antispasmodics yog qhov zoo.
Daniil Sviridov, kws kho mob leeg ntshav, Ekaterinburg
Kuv siv cov tshuaj hauv kev xyaum rau 3 xyoos. Nws tsis yog qhov yooj yim kom pom hauv cov chaw muag tshuaj; cov tshuaj muag tsuas yog muag ntawm cov ntsiab lus loj. Cov tshuaj yog ua hauj lwm zoo, txhim kho tshwm sim tom qab 3-4 lub lis piam ntawm kev noj ib txwm. Ntshav ua cov viscous tsawg dua, cov phab ntsa ntawm cov hlab ntsha loj dua qub. Nws cuam tshuam tsis zoo nrog feem ntau cov tshuaj, thaum kuv tsis xav kom noj tshuaj tua kab mob tib lub sijhawm ...
Valentina, 47 xyoo, Novorossiysk
Tus poj niam nws pib noj cov tshuaj rau lub hlis dhau los. Nws tau txais kev phais mob ntawm lub qhov muag retina, hauv tsev kho mob, cov tshuaj dej ntshiab tau nqig. Tom qab tso tawm, Kuv yuav tsum tau noj tshuaj, tab sis tus nqi ciali siab, yog li kuv yuav pheej yig dua. Yuav ua li cas regretted yuav luag tam sim ntawd.
Cov tshuaj ua ntej zoo dua. Kev txhim kho tuaj sai sai, txawm tias muaj cov kev mob tshwm sim me me uas ploj mus ntawm lawv tus kheej tom qab 4 hnub.
