Gluconorm yog qhov pheej yig, muaj txiaj ntsig zoo, kawm tau zoo, tab sis tsis siv tshuaj ib txwm muaj. Nws yog tshuaj rau cov neeg mob ntshav qab zib hom 2 kom txo qis ntshav qab zib. Ob yam tshuaj ntawd muab cov suab thaj txo qis - glibenclamide thiab metformin. Raws li kev tshawb nrhiav, kev siv ua ke ntawm cov tshuaj no tuaj yeem txo qis glycated hemoglobin los ntawm 1% piv nrog kev noj ib ntawm lawv. Rau cov neeg mob ntshav qab zib feem ntau, qhov no yog qhov txiaj ntsig zoo, uas ua rau nws tuaj yeem them nyiaj rau cov ntshav qab zib mellitus, thiab yog li ntawd, kom zam dhau nws cov kev mob lig.
Qhov tseem ceeb ntawm Gluconorm yog qhov phom sij ntawm cov ntshav qog ntshav qab zib, yog li lawv sim tsis txhob muab cov tshuaj rau cov neeg mob cuam tshuam sai sai rau hauv qab zib.
Kev ntsuas rau kev teem caij ntawm gluconorm
Hauv ntau tus neeg mob ntshav qab zib mellitus, ib qho tshuaj tsis tuaj yeem ruaj khov kho cov piam thaj li qub, yog li cov kws kho mob feem ntau nyiam siv tshuaj kho kom haum. Qhov ntsuas rau nws kev teem caij yog glycated hemoglobin saum toj no 6.5-7%. Qhov tseem ceeb tshaj plaws xav txog kev sib txuas ua ke ntawm metformin nrog sulfonylurea derivatives (PSM), gliptins thiab incretin mimetics. Tag nrho cov kev sib txuas ua ke cuam tshuam ob qho tag nrho cov tshuaj insulin thiab qhov ntim ntawm cov tshuaj insulin, thiab yog li ntawd muab cov nyhuv zoo.
Kev sib xyaw ua ke ntawm metformin + sulfonylurea yog qhov muaj ntau tshaj plaws. Cov khoom sib txuam tsis muaj peev xwm sib cuam tshuam nrog ib leeg, tsis txo qis kev ua tau zoo. Glibenclamide yog qhov muaj zog tshaj plaws thiab kawm ntawm txhua PSM. Nws muaj tus nqi qis thiab raug muag hauv txhua lub tsev muag tshuaj, yog li ntawd, ua ke nrog metformin, glibenclamide tau sau tseg yuav tsum ntau dua li lwm yam tshuaj. Txhawm rau siv yooj yim, ob lub tshuaj tiv thaiv tau tsim nrog ob cov khoom xyaw nquag no - Gluconorm thiab nws cov analogues.
Raws li cov lus qhia, Gluconorm tsuas yog siv tshwj xeeb rau kev mob ntshav qab zib hom 2, yog tias kev noj zaub mov zoo, kev ua kis las, thiab metformin tsis tso ntshav qabzib mus rau qhov tseem ceeb. Cov koob tshuaj ntawm cov tshuaj metformin yuav tsum tsis pub tsawg dua (2000 mg) lossis ib txwm zam rau cov kab mob ntshav qab zib. Tsis tas li, gluconorm tuaj yeem noj los ntawm cov neeg mob uas yav dhau los haus dej haus glibenclamide thiab metformin cais.
Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los
- Li qub ntawm qab zib -95%
- Kev tshem tawm ntawm cov hlab ntsha thrombosis - 70%
- Ntaus tau ntawm lub plawv dhia muaj zog -90%
- Kev tshem tawm ntshav siab - 92%
- Qhov nce hauv lub zog nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj -97%
Tshawb nrhiav pom: cov ntsiav tshuaj tsawg dua uas tus neeg mob siv sijhawm ib hnub, nws ntau dua nws xav ua raws li txhua tus kws kho mob cov ntawv sau, uas txhais tau tias qhov ua tau zoo dua ntawm kev kho mob. Ntawd yog, kev noj tshuaj Gluconorm hloov ntawm ob lub ntsiav tshuaj yog ib kauj ruam me me rau kev them nyiaj zoo rau ntshav qab zib.
Tsis tas li ntawd, qhov kev nce qib ob zaug ntxiv ntawm cov tshuaj ntawm cov piam thaj-txo cov ntsiav tshuaj tsis muab rau kev txo qis hauv qab zib. Ntawd yog, ob lub tshuaj hauv ib qho tshuaj me me yuav ua haujlwm ntau dua thiab muab cov kev mob tshwm sim tsawg dua li ib qho tshuaj hauv qhov ntau kawg.
Cov tshuaj sib xyaw thiab cuam tshuam ntawm cov tshuaj
Gluconorm yog tsim los ntawm lub tuam txhab Lavxias teb sab Pharmstandard hauv kev koom tes nrog Indian Biopharm. Cov tshuaj muaj nyob rau hauv 2 version:
- Gluconorm ntsiav tshuaj yog tsim hauv Is Nrias teb, ntim hauv tebchaws Russia. Cov tshuaj muaj cov tshuaj qub ntawm 2,5-400, uas yog, txhua ntsiav tshuaj ntawm metformin muaj 400 mg, glibenclamide 2.5 mg.
- Gluconorm Plus ntsiav tshuaj yog tsim nyob rau hauv Russia los ntawm cov tshuaj lag luam yuav khoom hauv Is Nrias teb thiab Tuam Tshoj. Lawv muaj 2 koob tshuaj: 2.5-500 rau cov neeg mob ntshav qab zib muaj cov tshuaj tiv thaiv insulin siab thiab 5-500 rau cov neeg mob tsis muaj qhov hnyav dhau, tab sis nrog lub cev tsis muaj zog txaus insulin.
Ua tsaug rau ntau txoj kev xaiv ntau npaum, koj tuaj yeem xaiv txoj kev sib piv rau txhua tus neeg mob ntshav qab zib hom 2.
Cia peb xav txog nyob rau hauv ntau dua yuav ua li cas lub Cheebtsam ntawm cov tshuaj Gluconorm ua hauj lwm. Metformin txo ob qho kev ua tiav tom qab thiab yoo mov glycemia feem ntau vim yog qhov txo qis hauv insulin tsis kam. Cov piam thaj tawm cov hlab ntsha sai dua li cov ntaub so ntswg rhiab rau cov kua dej. Metformin kuj tseem txo cov kev tsim cov piam thaj hauv lub cev los ntawm cov khoom uas tsis yog carbohydrate, maj mam nkag mus rau hauv cov ntshav los ntawm cov hnyuv.
Rau cov mob ntshav qab zib, cov khoom ntxiv ntawm metformin uas tsis cuam tshuam nrog kev txo qis hauv glycemia kuj tseem ceeb heev. Cov tshuaj tiv thaiv kev loj hlob ntawm angiopathy los ntawm normalizing ntshav lipids, txhim kho cov zaub mov noj nqaij. Raws li qee cov lus tshaj tawm, metformin tuaj yeem tiv thaiv qhov pom ntawm neoplasms. Raws li cov neeg mob, nws txo qis kev qab los noj mov, pab tswj lub cev kom zoo, txhawb lub cev yuag, thiab nce kev ua kom yuag.
Glibenclamide yog PSM 2 tiam. Nws ua haujlwm ncaj qha rau pancreatic beta hlwb: nws txo qis ntawm qhov pib ntawm lawv qhov rhiab heev rau cov piam thaj hauv ntshav, thiaj li ua cov insulin ntau ntxiv. Glibenclamide tseem tuaj yeem txhim kho glycogenogenesis, txheej txheem ntawm kev khaws cov piam thaj hauv cov leeg thiab nplooj siab. Tsis zoo li metformin, cov tshuaj no tuaj yeem ua rau mob ntshav qab zib, hnyav dua lwm yam neeg sawv cev ntawm pawg PSM - glimepiride thiab glyclazide. Glibenclamide suav hais tias yog qhov muaj zog tshaj plaws, tab sis kuj tseem muaj kev phom sij ntawm PSM. Nws tsis pom zoo rau cov neeg mob ntshav qab zib nrog qhov muaj kev pheej hmoo ntawm lub qog ntshav qab zib.
Yuav noj tshuaj Gluconorm li cas
Cov kev mob tshwm sim feem ntau ntawm metformin yog kev zom, glibenclamide - mob ntshav qab zib. Koj tuaj yeem txo qhov kev pheej hmoo tsis zoo ntawm kev kho nrog gluconorm, noj tshuaj rau tib lub sijhawm ua zaub mov thiab maj mam nce koob tshuaj, pib nrog qhov tsawg kawg nkaus.
Dosage ntawm yeeb tshuaj Gluconorm raws li cov lus qhia:
| Cov yam ntxwv ntawm kev txais tos | Gluconorm | Gluconorm Plus | |
| 2,5-500 | 5-500 | ||
| Pib tshuaj, tab. | 1-2 | 1 | 1 |
| Lub koob tshuaj ntawd tsawg, tab. | 5 | 6 | 4 |
| Kev xaj ntau zuj zus | Peb nce nce koob tshuaj los ntawm 1 ntsiav tshuaj txhua 3 hnub yog tias tus neeg mob yav tas los noj tshuaj metformin tiav. Yog tias cov tshuaj metformin tsis tau raug coj los kho rau tus mob ntshav qab zib, lossis nws tsis ua siab ntev rau nws, ntxiv cov ntsiav tshuaj thib ob tsis pub dhau 2 lub lis piam tom qab. | ||
| Txwv tsis pub cov ntshav qab zib mob raum thiab mob siab | Txhawm rau tshem tawm cov mob gluconorm ntawm lub cev, daim siab ua haujlwm zoo thiab lub raum ua haujlwm yog qhov tsim nyog. Yog tias tsis muaj txhij txhua ntawm cov kabmob ntawm cov neeg kawm tsis hnyav, kev qhia pom zoo kom ua kom tsawg li ntau tau. Pib txij li qib tsis ua haujlwm ntawm qhov tsis ua hauj lwm, cov tshuaj txwv tsis pub noj. | ||
| Daim ntawv thov hom | Haus 1 lub tshuaj thaum noj tshais, 2 lossis 4 thaum noj tshais thiab noj hmo. 3, 5, 6 tab. muab faib ua 3 koob. | ||
Nrog muaj zog insulin tsis kam, uas yog cov yam ntxwv ntawm cov neeg rog nrog ntshav qab zib, metformin ntxiv yuav raug tshuaj. Feem ntau hauv qhov no lawv haus nws ua ntej mus pw. Qhov zoo tshaj plaws txhua hnub koob tshuaj metformin raug txiav txim siab yog 2000 mg, qhov siab tshaj - 3000 mg. Ib txoj kev nce ntxiv hauv cov tshuaj yog qhov txaus ntshai nrog cov kab mob lactic acidosis.
Muaj qhov tsis muaj cov carbohydrates hauv cov zaub mov, Gluconorm ua rau lub cev tsis muaj ntshav qab zib. Txhawm rau tiv thaiv nws, cov ntsiav tshuaj yog qaug cawv nrog cov zaub mov tseem ceeb. Cov khoom lag luam yuav tsum muaj cov carbohydrates, feem ntau qeeb. Koj tuaj yeem tsis cia ncua sijhawm ntev nruab nrab ntawm pluas noj, yog li cov neeg mob tau pom zoo kom noj khoom txom ncauj ntxiv. Kev soj ntsuam cov ntshav qab zib qhia tau hais tias nrog kev ua lub cev sib zog, qab zib tuaj yeem poob rau ob peb feeb xwb. Lub sijhawm no, koj yuav tsum tau ua tib zoo saib xyuas koj txoj kev noj qab haus huv.
Phiv thiab haus tshaj
Cov kev mob tshwm sim tuaj yeem ua rau tus neeg mob ntshav qab zib ntsib thaum siv Gluconorm lossis nws cov analogues:
- cov qog ntshav ntshav yog qhov tshwm sim los ntawm PSM;
- kev tawm tsam los ntawm cov hnyuv hauv plab, lawv qhov ua rau yog metformin. Raws li kev txheeb xyuas, feem ntau cov neeg mob ntshav qab zib yuav pib mob plab thiab mob thaum sawv ntxov. Cov lus qhia rau kev siv ceeb toom tias kev mob plab thiab ntuav tseem ua tau. Yog tias muaj teeb meem zoo li no tshwm sim, tsis txhob tso tseg Gluconorm tam sim ntawd, feem ntau hauv ib lub lis piam lub cev hloov kho thiab tsis teb rau cov tshuaj zoo li ntawd;
- ua txhaum ntawm cov txheej txheem ntawm cov ntshav tsim. Tus nqi ntawm cov khoom sib xyaw hauv cov ntshav yuav poob. Thaum kho nrog Gluconorm txuas mus ntxiv, cov ntshav sib xyaw ua ke tau rov ua haujlwm;
- lactic acidosis yog ib qho mob uas tsis tshua pom muaj ntshav qab zib ntau, ua rau muaj hom 2. Yog tsis muaj kev pab kho mob, nws ua rau lub suab tsis xeev;
- intolerance rau cawv nyob rau hauv mob daim ntawv;
- lub hauv nruab nrab cov hlab ntsha tuaj yeem teb rau kev siv gluconorm nrog mob taub hau thiab tsis muaj zog;
- kev ua xua muaj peev xwm ua tau, mus txog anaphylactic.
Cov kev mob tshwm sim xws li hypoglycemia thiab lactic acidosis yog qhov tshwm sim ntawm kev noj ntau dhau ntawm Gluconorm. Nws tuaj yeem yog:
- Ncaj qha: cov ntshav qab zib tau haus ntau tshaj qhov tau teev tseg.
- Indirect. Kev mob hypoglycemia tuaj yeem tshwm sim thaum tsis muaj zaub mov carbohydrates hauv cov zaub mov lossis kua nplaum hauv lub cev sai sai thaum kev tawm dag zog lub cev thiab cov kev ntxhov siab sai, ob qho tib si kev xav thiab lub cev. Kev tsim ntawm lactate nce nyob rau hauv cov kev mob ntawm cawv intoxication, hloov khoom nruab nrog cev ua rau hypoxia, nrog kev raug mob hnyav thiab kis kab mob.
Kev ua rau kev noj haus ntau tshaj tawm raws li cov lus qhia: mob ntshav qab zib tsawg kawg yog nres los ntawm cov piam thaj lossis cov khoom lag luam nrog nws cov ntsiab lus siab. Cov kab mob lactic acidosis thiab mob ntshav siab, nrog rau qhov tsis nco qab, yuav tsum tau mus pw hauv tsev kho mob sai.
Cov Yuav Tsum Muaj
Thaum Gluconorm rau ntshav qab zib siv tsis tau:
- nrog rau kev nkag siab ntxiv rau cov khoom siv hauv cov ntsiav tshuaj. Cov contraindication no suav nrog kev ua xua, thiab tshaj tawm yam tsis xav ua uas yuav tsum tau txiav tawm cov tshuaj;
- yog tias kuaj pom 1 yam mob ntshav qab zib;
- thaum kho kev mob ntshav qab zib, mob hnyav thiab raug mob. Kev txiav txim siab txog kev hloov mus ib ntus rau kev kho tshuaj insulin yog ua los ntawm tus kws kho mob uas koom nrog;
- nrog mob raum tsis zoo lossis muaj kev pheej hmoo siab ua tsis taus;
- thaum cev xeeb tub thiab HB. Qhov kev txwv ntawm kev siv Gluconorm yog qhov nruj, txij li PSM hauv kev sib xyaw ntawm cov ntsiav tshuaj tuaj yeem cuam tshuam kev loj hlob ntawm tus me nyuam hauv plab, ua rau muaj ntshav qab zib hauv menyuam;
- thaum noj cov tshuaj tua kab mob. Kev sib xyaw ntawm Gluconorm nrog miconazole lossis fluconazole yog fraught nrog mob ntshav qab zib tsawg. Daim ntawv teev cov tshuaj uas cuam tshuam rau kev ua ntawm Gluconorm tau qhia nyob rau hauv cov lus qhia rau kev siv;
- yog tias tus mob ntshav qab zib tau ntsib mob lactic acidosis lossis muaj kev pheej hmoo siab txog kev txhim kho nws.
Kev sib piv thiab hloov chaw
| Hloov chaw | Chaw tsim tshuaj paus | Lub Khw |
| Tiav gluconorm analogues | Canonpharma | Metglib |
| Berlin-Chemie, Guidotti Laboratory | Glibomet | |
| Gluconorm Plus Analogs | Pharmasynthesis | Glibenfage |
| Tojntxas | Metglib Yuam | |
| Merck Sante | Glucovans | |
| Valeant | Bagomet Ntxiv | |
| Metformin kev npaj | Vertex, Gideon Richter, Medisorb, IzvarinoFarma, thiab lwm yam. | Metformin |
| Pharmasynthesis | Merifatin | |
| Merk | Ntsia hauv qab | |
| Glibenclamide npaj | Pharmasynthesis | Statiglin |
| Cov Kws Tshuaj, Atoll, Moskhimpharmpreparaty, thiab lwm yam. | Glibenclamide | |
| Berlin Chemie | Maninil | |
| Ob-tshuaj tivthaiv: metformin + PSM | Sanofi | Amaryl, yog ib feem ntawm PSM glimepiride |
| Akrikhin | Glimecomb, muaj PSM Gliclazide |
Ua kom tiav cov tshuaj analogues, ntxiv rau metformin thiab glibenclamide cais, tuaj yeem ua kom tsis muaj teeb meem hauv kev noj haus tib yam li Gluconorm. Yog tias koj npaj siab yuav hloov mus rau kev kho mob nrog lwm tus sulfonylurea derivative, koob tshuaj yuav tau rov xaiv duaCov. Cov kws kho mob pom zoo kom hloov los ntawm Gluconorm mus rau Amaryl lossis Glimecomb rau cov neeg mob ntshav qab zib uas muaj hom 2 carbohydrate cuam tshuam, uas feem ntau ntsib kev mob hypoglycemia.
Raws li kev txheeb xyuas, cov txiaj ntsig ntawm Gluconorm thiab nws cov analogues yog ze, tab sis cov neeg mob ntshav qab zib tseem nyiam lub German Glybomet, suav tias nws yog cov tshuaj zoo tshaj.
Kev cai cia thiab nqe
Gluconorm siv tau rau 3 xyoos txij li hnub ntau lawm. Gluconorm Plus pub rau muab tsis pub tshaj 2 xyoos. Cov lus qhia tsis muaj cov kev cai tshwj xeeb rau kev cia khoom, nws yog qhov txaus los soj ntsuam lub ntsuas cua sov tsis pub tshaj 25 degrees.
Cov neeg mob ntshav qab zib hauv Lavxias tuaj yeem tau txais ob qho tshuaj raws li cov kws kho mob dawb tau sau tseg los ntawm kws kho mob dav dav lossis tus mob endocrinologist. Kev yuav ntawm tus kheej yuav raug nqi pheej yig: tus nqi ntawm ib pob ntawm 40 ntsiav tshuaj ntawm Gluconorm yog txog 230 rubles, Gluconorm Plus cov nqi los ntawm 155 txog 215 rubles. rau 30 ntsiav tshuaj. Rau kev sib piv, tus nqi ntawm thawj Glibomet yog li 320 rubles.
