Amaryl muaj cov tshuaj glimepiride, uas zwm rau ntawm ib qho tshiab, thib peb, tiam ntawm sulfonylurea derivatives (PSM). Cov tshuaj no tseem kim dua li glibenclamide (Maninil) thiab glyclazide (Diabeton), tab sis tus nqi sib txawv tsuas yog muaj cov neeg ua haujlwm siab, kev txiav txim siab sai, ua rau muaj kev cuam tshuam tsawg dua ntawm tus txiav, thiab txo qis kev pheej hmoo ntawm hypoglycemia.
Nrog Amaril, beta hlwb tau ploj zuj zus qeeb dua nrog cov tiam dhau los ntawm sulfonylureas, yog li qhov kev nce qib ntawm ntshav qab zib tau qeeb thiab kev kho tshuaj insulin yuav xav tau tom qab.
Kev tshuaj xyuas cov tshuaj muaj lub siab zoo: nws txo cov piam thaj kom zoo, yog qhov yooj yim rau siv, lawv haus cov ntsiav tshuaj ib hnub, tsis hais txog ntawm qhov koob tshuaj. Ntxiv rau cov ntshiab glimepiride, nws qhov sib xyaw nrog metformin yog tsim - Amaril M.
Qhia me ntsis
| Nkaus | Txo cov ntshav qab zib, cuam tshuam nws theem ntawm ob sab:
Tsis tas li ntawd, cov tshuaj txo cov kev pheej hmoo ntawm thrombosis, normalizes cov roj cholesterol, thiab txo qis oxidative kev nyuaj siab. Amaryl raug tso tawm hauv cov zis, ib feem los ntawm cov hnyuv, yog li nws tuaj yeem siv rau hauv cov neeg mob raum tsis ua haujlwm, yog tias lub raum ua haujlwm tsis zoo ib feem. |
| Cov Khoom Qhia | Mob ntshav qab zib tsuas yog 2 hom. Ib qho yuav tsum tau ua ua ntej rau kev siv yog qee khaws cia beta hlwb, seem synthesis ntawm lawv tus kheej cov insulin. Yog tias tus txiav tsis dhau los tsim cov tshuaj hormones, Amaril tsis tau hais kom ua. Raws li cov lus qhia, cov tshuaj tuaj yeem noj nrog metformin thiab insulin kho. |
| Tsuas tshuaj | Amaryl yog tsim nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj muaj txog li 4 mg ntawm glimepiride. Rau qhov yooj yim ntawm kev siv, txhua qhov tshuaj tau nws tus kheej xim. Lub koob tshuaj pib yog 1 mg. Nws yog noj rau 10 hnub, tom qab uas lawv pib maj mam nce ntxiv kom txog thaum qab zib zoo li qub. Qhov ntau kawg pub rau noj yog 6 mg. Yog tias nws tsis them nyiaj rau cov ntshav qab zib, cov tshuaj los ntawm lwm pab pawg lossis cov tshuaj insulin ntxiv rau kev kho mob. |
| Noj ntau dhau | Tshaj dhau qhov siab tshaj qhov kawg yuav ua rau muaj ntshav qab zib nyob ntev. Tom qab ib txwm muaj suab thaj, nws tuaj yeem rov qab poob rau lwm 3 hnub. Txhua lub sijhawm no, tus neeg mob yuav tsum nyob hauv qab kev saib xyuas ntawm cov txheeb ze, nrog kev siv ntau dhau - hauv tsev kho mob. |
| Cov Yuav Tsum Muaj |
Amaryl raug tso tseg ib ntus thiab hloov nrog cov tshuaj insulin thaum lub sijhawm cev xeeb tub thiab lactation, mob hnyav ntshav qab zib, los ntawm ketoacidosis mus rau hyperglycemic coma. Nrog rau cov kis kab mob, kev raug mob, kev xav ntau dhau, Amaril yuav tsis txaus rau cov suab thaj li qub, yog li kev kho mob ntxiv nrog insulin, feem ntau ntev. |
| Kev phom sij ntawm hypoglycemia | Cov ntshav qab zib poob qis yog tias cov ntshav qab zib tsis nco qab noj mov los yog tsis ntxiv cov piam thaj hauv lub sijhawm ua si. Txhawm rau kev loj hlob ntawm glycemia, koj yuav tsum noj cov zaub mov sai sai, feem ntau yog ib qho qab zib, ib khob kua txiv los sis tshuaj yej qab zib tau txaus. Yog tias cov koob tshuaj ntawm Amaril tau dhau lawm, kev txo qis ntshav qab zib hauv lub cev yuav rov qab los ntau zaus thaum lub sijhawm tshuaj. Hauv qhov no, tom qab thawj zaug ntawm cov piam thaj li ib txwm, lawv sim tshem glimepiride los ntawm cov hnyuv: lawv ua kom ntuav, haus dej adsorbents lossis laxative. Cov kev noj tshuaj rau lub qog ntshav ntshav siab heev yog yuav tsum tau tso cov piam thaj hauv lub cev. |
| Sab sij huam | Ntxiv rau hypoglycemia, thaum noj Amaril, teeb meem kev zom zaub mov tuaj yeem pom (hauv tsawg dua 1% ntawm cov neeg mob), kev ua xua, los ntawm tawm pob thiab khaus khaus mus rau anaphylactic shock (<1%), kev cuam tshuam los ntawm lub siab, qhov hloov pauv ntawm cov ntshav muaj zog (<0.1%) Cov. |
| Cev xeeb tub thiab GV | Kev qhia nruj me ntsis txwv kev kho mob nrog Amaril thaum cev xeeb tub thiab HBVCov. Cov tshuaj kis tau los ntawm qhov kev tiv thaiv placental thiab nkag rau hauv tus menyuam hauv plab cov ntshav, nkag mus rau lub mis. Yog tias tus neeg mob cev xeeb tub lossis tus mob ntshav mis mob ntshav qab zib tsis tsum tsis noj tshuaj, tus menyuam muaj feem yuav muaj ntshav qab zib tsawg. |
| Yeeb tshuaj sib cuam tshuam | Qhov tshwm sim ntawm Amaril yuav hloov pauv nrog kev siv lwm yam tshuaj: cov tshuaj hormones, antihypertensive, qee yam tshuaj tua kab mob thiab tshuaj tua kab mob. Tag nrho cov npe muaj nyob hauv cov lus qhia rau kev siv. |
| Muaj pes tsawg leeg | Cov tshuaj muaj sia yog glimepiride (Amaril M muaj glimepiride thiab metformin), cov khoom siv pabcuam rau kev tsim cov ntsiav tshuaj thiab nce nws lub neej txee: sodium glycolate, lactose, cellulose, polyvidone, magnesium stearate, zas. |
| Chaw tsim tshuaj paus | Sanofi Corporation, glimepiride yog tsim nyob hauv lub teb chaws Yelemees, ntsiav tshuaj thiab ntim hauv ltalis. |
| Nqi | Amaryl: 335-1220 rub. rau 30 ntsiav tshuaj, tus nqi nyob ntawm qhov muab ntau npaum li cas. Cov pob loj tshaj plaws - 90 ntsiav tshuaj ntawm 4 mg txhua tus nqi txog 2700 rubles. Amaril M: 750 rub. rau 30 ntsiav tshuaj. |
| Cia | 3 xyoos Cov tshuaj yuav tsum muab tso rau qhov chaw ncav cuag ntawm cov menyuam yaus, vim tias kev siv tshuaj tsis raug tswj los ntawm Amaril tuaj yeem tsim kev puas tsuaj rau kev noj qab haus huv. |
Nkag Tawm Cov Cai
Amaryl ntsiav tshuaj raug sau ua ob yam:
- Yog tias ntshav qab zib tsis nyob hauv thawj xyoo, thiab metformin tsis txaus los them rau nws.
- Thaum pib ntawm kev kho mob, nrog rau metformin thiab noj haus, yog tias muaj glycated hemoglobin ntau ((8%). Tom qab them nyiaj rau tus kab mob, qhov xav tau rau cov tshuaj hypoglycemic tsawg, thiab Amaryl tau tso tseg.
Cov tshuaj tau noj nrog zaub mov.Cov. Cov ntsiav tshuaj tsis tuaj yeem tsoo, tab sis tuaj yeem faib ua ib nrab ntawm kev pheej hmoo. Kev kho Amaril yuav tsum tau noj haus kho kom raug:
Mob ntshav qab zib thiab siab surges yuav yog ib yam dhau los
- Li qub ntawm qab zib -95%
- Kev tshem tawm ntawm cov hlab ntsha thrombosis - 70%
- Ntaus tau ntawm lub plawv dhia muaj zog -90%
- Kev tshem tawm ntshav siab - 92%
- Qhov nce hauv lub zog nruab hnub, txhim kho pw tsaug zog thaum hmo ntuj -97%
- cov pluas noj thaum lawv noj tshuaj yuav tsum muaj ntau;
- Nyob rau hauv tsis muaj qhov yuav tsum tau koj hla zaub mov. Yog tias nws tsis tuaj yeem noj tshais, Amaril qhov kev txais tos yog pauv mus noj hmo;
- nws yog ib qho tsim nyog los npaj cov kev sib koom ua ke ntawm cov carbohydrates hauv cov ntshav. Lub hom phiaj no tau ua tiav los ntawm cov pluas noj mov nquag (tom qab 4 teev), kev faib tawm ntawm cov carbohydrates hauv txhua lub tais. Qhov qis dua glycemic Performance index ntawm cov zaub mov, qhov yooj yim dua nws yog ua tiav kev them nyiaj ntshav qab zib.
Amaril yog qaug cawv rau xyoo tsis noj sijhawm so. Yog tias qhov siab tshaj plaws tau tso tseg kom txo cov piam thaj, qhov nrawm nrawm yuav tsum hloov mus rau txoj kev kho tshuaj insulin.
Lub sijhawm ua
Amaryl muaj cov khoom siv bioavailability tag nrho, 100% cov tshuaj tau mus txog qhov chaw txiav txim. Raws li cov lus qhia, qhov siab tshaj plaws ntawm glimepiride hauv cov ntshav tau tsim tom qab 2.5 teev. Tag nrho lub sijhawm dhau ntawm qhov kev txiav txim siab tshaj 24 teev, ntau dua qhov tsuas tshuaj, ntev dua Amaril ntsiav tshuaj yuav ua haujlwm.
Vim nws lub sijhawm ntev, cov tshuaj raug tso cai kom noj ib zaug ib hnub. Muab hais tias 60% ntawm cov neeg mob ntshav qab zib tsis txaus siab ua raws li tus kws kho mob cov lus qhia, ib koob tshuaj muaj peev xwm txo qis kev noj tshuaj tsis tau 30%, thiab yog li txhim kho cov ntshav qab zib cov mob.
Cawv tau zoo
Cov dej cawv ua rau Amaryl tsis paub meej, lawv tuaj yeem ob leeg txhim kho thiab tsis muaj zog nws cov nyhuv. Txoj kev pheej hmoo ntawm lub neej ntshav nce ntshav qab zib tsawg zuj zus, pib nrog kev haus luam yeeb mob pes tsawg. Raws li cov neeg mob ntshav qab zib, haus cawv kom zoo tsis pub ntau tshaj ib khob ntawm vodka lossis ib khob caw.
Amaril qhov piv txwv
Cov tshuaj muaj ntau qhov sib piv nrog pheej yig dua nrog tib cov tshuaj nquag thiab tshuaj ntau npaum li cas, cov tshuaj hu ua generics. Yeej, cov no yog ntsiav tshuaj ntawm kev tsim khoom hauv teb chaws, los ntawm cov khoom lag luam txawv teb koj tuaj yeem yuav tsuas yog hauv Croatian Glimepirid-Teva. Raws li kev txheeb xyuas, cov Lavxias analogues tsis muaj qhov phem dua li cov tshuaj Amaril ntshuam.
| Amaril qhov piv txwv | Lub teb chaws ntau lawm | Chaw tsim tshuaj paus | Nqe rau qhov ntau kawg cov tshuaj ntawd, tshiav. |
| Glimepiride | Lavxias | Atolla Vertex Xaws Pob Kws Cov Ntawv Muag Khoom-Leksredstva, | 110 |
| Glimepiride Canon | Canonfarm Ntau Lawm. | 155 | |
| Diamerid | Akrikhin | 180 | |
| Glimepiride-teva | Croatia | Pliva ntawm Khrvatsk | 135 |
| Glemaz | Argentina | Kimika Montpellier | tsis muaj nyob hauv cov chaw muag tshuaj |
Amaryl lossis Diabeton
Tam sim no, glimepiride thiab daim ntawv ntev ntev ntawm glyclazide (Diabeton MV thiab analogues) tau suav hais tias yog PSM tshiab tshaj plaws thiab nyab xeeb. Ob qho tshuaj yeeb tshuaj muaj tsawg dua li lawv cov neeg ua ntej mus ua rau mob ntshav nce siab ntau.
Thiab tseem, Amaryl ntsiav tshuaj rau ntshav qab zib yog qhov zoo:
- lawv cuam tshuam qhov hnyav ntawm cov neeg mob tsawg dua;
- tsis yog li qhov kev hais tawm tsis zoo ntawm cov kab mob plawv;
- cov mob ntshav qab zib xav tau qhov tshuaj tsawg dua (qhov ntau tshaj plaws ntawm Diabeton yog kwv yees li 3 mg ntawm Amaril);
- qhov txo qis hauv qab zib thaum noj Amaril yog nrog los ntawm kev poob qis hauv qib hauv insulin. Rau Diabeton, qhov no sib piv yog 0.07, rau Amaril - 0.03. Hauv seem PSM, qhov sib piv yog qhov tsis zoo: 0.11 rau glipizide, 0.16 rau glibenclamide.
Amaryl lossis Glucophage
Hais lus nruj heev, cov lus nug Amaril lossis Glucophage (metformin) yuav tsum tsis txhob nug. Glucophage thiab nws cov analogues rau cov ntshav qab zib hom 2 yeej ib txwm sau tseg rau hauv thawj qhov chaw, txij li thaum lawv siv tau zoo dua li lwm cov tshuaj ua rau qhov tseem ceeb ntawm tus kabmob - insulin tsis kam. Yog tias tus kws kho mob tsuas sau cov ntsiav tshuaj Amaryl xwb, nws lub peev xwm yog tsim nyog ua tsis ntseeg siab.
Txawm hais tias muaj kev sib piv ntawm kev nyab xeeb, cov tshuaj no cuam tshuam ncaj qha rau tus txiav, uas txhais tau tias nws ua kom luv ntawm kev tsim hluav taws xob ntawm koj tus kheej insulin. PSM raug xaj tsuas yog tias metformin tsis raug tiv thaiv tsis zoo lossis nws qhov siab tshaj plaws yuav tsis txaus rau cov glycemia ib txwm. Raws li txoj cai, qhov no yog qhov ua rau mob ntshav qab zib ntau yam, lossis muaj mob ntev ntev.
Amaril thiab Yanumet
Yanumet, zoo li Amaryl, cuam tshuam rau ob theem insulin thiab insulin kuj. Cov tshuaj sib txawv ntawm cov txheej txheem ntawm kev ua thiab tshuaj qauv, yog li lawv tuaj yeem sib koom ua ke. Yanumet yog ib qho tshuaj kuj tshiab, yog li ntawd nws raug nqi los ntawm 1800 rubles. rau pob khoom me tshaj plaws. Hauv Lavxias, nws cov analogues tau sau npe: Combogliz thiab Velmetia, uas tsis pheej yig dua li qhov qub.
Feem ntau, cov mob ntshav qab zib tuaj yeem ua tiav los ntawm kev sib xyaw ua ke ntawm pheej yig metformin, kev noj zaub mov zoo, kev tawm dag zog, qee zaum cov neeg mob xav tau PSM. Yanumet muaj nqis yuav tsuas yog them nqi nws tsis tseem ceeb rau kev siv nyiaj.
Awb M
Kev tsis ua raws li kev mob ntshav qab zib nrog kev kho mob kws kho mob yog qhov laj thawj rau kev decompensation ntawm ntshav qab zib. Tshaj tawm ntawm txoj kev kho kev kho rau txhua yam mob tshwm sim ib txwm txhim kho nws cov txiaj ntsig, yog li, rau cov neeg mob xaiv yeem, cov tshuaj sib xyaw ua ke yog qhov zoo dua. Amaryl M muaj cov tshuaj feem ntau txo cov tshuaj qab zib: metformin thiab PSM. Txhua lub ntsiav tshuaj muaj 500 mg ntawm metformin thiab 2 mg ntawm glimepiride.
Nws yog tsis yooj yim sua kom meej meej sib npaug ob yam tshuaj lom hauv ib ntsiav tshuaj rau cov neeg mob sib txawv. Hauv nruab nrab theem ntawm ntshav qab zib, ntau metformin, tsawg dua glimepiride yuav tsum. Tsis pub ntau tshaj 1000 mg ntawm metformin pub rau ib zaug, cov neeg mob uas mob hnyav yuav tsum haus Amaril M peb zaug ib hnub. Txhawm rau xaiv cov tshuaj ntau npaum li cas, nws raug nquahu rau cov neeg mob uas tau txiav txim siab coj Amaril cais thaum noj tshais thiab Glucofage peb zaug ib hnub.
