Qhov xav tau rau cov tshuaj insulin tshwm sim nyob rau hauv cov ntshav qab zib ntawm thawj lossis thib ob, thaum ua haujlwm lub cev thiab kev noj zaub mov zoo tsis tuaj yeem ua rau cov ntshav qabzib ntau dua.
Ua ntej siv cov tshuaj insulin Detemir yuav tsum nkag siab yuav ua li cas kom tswj hwm cov tshuaj hormone, nyob rau hauv rooj plaub no nws tsis tuaj yeem siv thiab qhov kev mob tshwm sim twg tuaj yeem ua rau.
Pharmacological kev txiav txim ntawm cov quav yeeb tshuaj
Detemir insulin yog tsim tawm siv cov roj av deoxyribonucleic acid (DNA) biotechnology siv tshuaj tua kab mob hu ua Saccharomyces cerevisiae.
Cov tshuaj insulin yog cov tshuaj tseem ceeb ntawm cov tshuaj Levemir flekspen, uas tau tawm hauv qhov tsim ntawm kev daws hauv kev yooj yim 3 ml syringe cwjmem (300 PIECES).
Qhov tib neeg cov tshuaj hormones analogue khi rau cov xov tooj ntawm tes txais txiaj ntsig thiab ua rau cov txheej txheem lom.
Tib neeg cov tshuaj insulin pab txhawb kev ua kom muaj kev ua haujlwm hauv qab no hauv lub cev:
- stimulation ntawm qabzib uptake los ntawm peripheral hlwb thiab cov ntaub so ntswg;
- piam thaj metabolism tswj tau;
- kev txwv ntawm gluconeogenesis;
- nce protein synthesis;
- kev tiv thaiv ntawm lipolysis thiab tiv thaiv proteolysis hauv cov rog rog.
Ua tsaug rau tag nrho cov txheej txheem no, muaj kev txo cov ntshav qab zib kom tsawg. Tom qab txhaj cov tshuaj insulin, Detemir ncav cuag nws cov txiaj ntsig zoo tshaj tom qab 6-8 teev.
Yog tias koj nkag rau qhov kev daws teeb meem ob zaug hauv ib hnub, tom qab ntawv qhov sib luag ntawm cov tshuaj insulin tiav tom qab ob lossis peb qhov kev txhaj tshuaj. Kev txiav txim siab ntawm ib tug neeg sab hauv ntawm Detemir insulin yog tus neeg qis dua lwm cov tshuaj insulin hauv paus.
Qhov tshuaj no muaj cov nyhuv tib yam rau txiv neej thiab poj niam. Nws qhov kev faib khoom nruab nrab yog kwv yees li 0.1 l / kg.
Lub sijhawm kawg ntawm ib nrab-lub neej ntawm insulin txhaj nyob rau hauv daim tawv nqaij yog nyob ntawm kev ntau npaum li cas ntawm cov tshuaj thiab yog kwv yees li 5-7 teev.
Cov lus qhia rau kev siv tshuaj
Tus kws kho mob suav qhov ntau npaum li cas ntawm cov tshuaj, noj mus rau hauv tus account lub concentration ntawm cov piam thaj hauv ntshav qab zib.
Cov koob tshuaj yuav tsum raug kho nyob rau hauv cov ntaub ntawv ntawm kev ua txhaum ntawm tus neeg mob lub cev noj mov, nce kev ua si lossis muaj lwm yam txuj ci. Insulin Detemir tuaj yeem raug siv los ua cov tshuaj tseem ceeb, ua ke nrog bolus insulin lossis nrog rau cov tshuaj txo cov ntshav qab zib.
Qhov kev txhaj tshuaj tuaj yeem ua tsis pub dhau 24 teev nyob rau txhua lub sijhawm, qhov tseem ceeb yog yuav soj ntsuam tib lub sijhawm txhua hnub. Cov kev cai yooj yim rau kev tswj hwm cov tshuaj hormones:
- Qhov kev txhaj tshuaj yog tsim nyob rau hauv daim tawv nqaij mus rau hauv thaj chaw hauv plab, xub pwg, pob tw lossis ncej puab.
- Txhawm rau kom txo kev ntxim nyiam ntawm lipodystrophy (mob nqaij ntshiv nqaij), thaj chaw txhaj tshuaj yuav tsum tau hloov ua ntu zus.
- Cov neeg muaj hnub nyoog tshaj 60 xyoo thiab cov neeg mob raum lossis lub siab ua rau lub siab xav tau qhov ntsuas cov kua nplaum thiab cov tshuaj insulin ntau dua.
- Thaum hloov pauv ntawm lwm cov tshuaj lossis hauv thawj theem ntawm txoj kev kho, nws yog qhov yuav tsum tau ua tib zoo saib xyuas theem ntawm glycemia.
Nws yuav tsum raug sau tseg tias hauv kev kho mob ntawm cov tshuaj insulin Detemir tsis xav tau qhov nce hauv qhov hnyav ntawm tus neeg mob. Ua ntej taug kev ntev ntev, tus neeg mob yuav tsum sab laj nrog tus kws kho mob tshwj xeeb txog kev siv cov tshuaj, txij li hloov thaj chaw lub sij hawm cuam tshuam cov sijhawm teem rau kev siv tshuaj insulin.
Kev txiav tawm ntawm txoj kev kho kom zoo tuaj yeem ua rau lub xeev ntawm hyperglycemia - nce qib ntawm cov piam thaj ntau, lossis tseem muaj ketoacidosis mob ntshav qab zib - kev ua txhaum ntawm cov metabolism hauv lub cev vim tias tsis muaj cov tshuaj insulin. Yog tias tus kws kho mob tsis tiv tauj sai, qhov ua tiav yuav tshwm sim tau.
Kev mob hypoglycemia yog tsim thaum lub cev qias lossis tsis txaus noj nrog cov zaub mov, thiab cov koob tshuaj insulin, nyeg, yog qhov siab heev. Txhawm rau txhawm rau nce ntxiv cov piam thaj hauv cov ntshav, koj yuav tsum noj ib qho qab zib, qab chocolate, qee yam qab zib.
kub taub hau lossis ntau yam mob feem ntau nce ntxiv qhov kev xav tau ntawm lub cev. Qhov kev hloov kho ntawm txoj kev daws teeb meem yuav tsim nyog hauv kev txhim kho pathologies ntawm ob lub raum, mob siab, lub qog, cov qog pituitary thiab cov qog adrenal.
Thaum muab cov tshuaj insulin thiab thiazolidinediones sib xyaw, nws yog ib qho tsim nyog yuav tsum coj mus rau hauv qhov tseeb tias lawv tuaj yeem pab txhawb kev txhim kho kev mob plawv thiab mob ntsws tsis ua hauj lwm.
Thaum siv yeeb tshuaj, kev hloov pauv hauv kev xav thiab psychomotor tus cwj pwm yog tau.
Cov tshuaj tiv thaiv thiab ua kom raug mob
Xws li, contraindications rau kev siv cov insulin Detemir tsis muaj. Qhov kev txwv tsuas yog cuam tshuam rau cov tib neeg muaj kev ywj pheej rau cov tshuaj yeeb dej caw thiab ob xyoos vim qhov kev tshawb fawb txog kev cuam tshuam ntawm cov tshuaj insulin rau cov menyuam yaus tseem tsis tau ua.
Thaum lub sijhawm cev tes taw, cov tshuaj yuav siv tau, tab sis nyob rau hauv kev saib xyuas ntawm tus kws kho mob.
Ntau cov kev tshawb fawb tsis qhia txog kev mob tshwm sim hauv leej niam thiab nws tus menyuam yug tshiab nrog kev qhia ntawm cov tshuaj insulin thaum nws xeeb tub.
Nws ntseeg tau tias cov tshuaj no tuaj yeem siv nrog niam mis, tab sis tsis muaj kev tshawb nrhiav. Yog li, rau cov niam cev xeeb tub thiab lactating, tus kws kho mob kho cov tshuaj ntawm cov tshuaj insulin, kev hnyav ua ntej nws muaj txiaj ntsig rau leej niam thiab muaj kev pheej hmoo rau nws tus menyuam.
Txog ntawm qhov tsis zoo rau lub cev, cov lus qhia rau kev siv muaj ib daim ntawv teev ntau:
- Ib lub xeev ntawm cov ntshav ntog lub cev muaj tus yam ntxwv xws li tsaug zog, txob taus, pallor ntawm daim tawv nqaij, tshee tshee, mob taub hau, tsis meej pem, nriaj teeb, tsaus muag, tachycardia. Qhov xwm txheej no tseem tseem hu ua insulin shock.
- Cov tshuaj tiv thaiv ib ce hauv ib cheeb tsam - o thiab liab ntawm thaj chaw txhaj tshuaj, khaus, nrog rau cov tsos ntawm lipid dystrophy.
- Kev ua xua, angioedema, urticaria, tawv nqaij ua pob thiab tawm hws.
- Ua txhaum ntawm lub plab zom mov - xeev siab, ntuav, mob plab, raws plab.
- Ua tsis taus pa, ua kom ntshav siab.
- Pom kev tsis pom kev - qhov hloov ntawm qhov tsis pom tseeb uas ua rau retinopathy (mob ntawm qhov mob ntawm qhov retina).
- Kev tsim tawm ntawm cov hlab hlwb paj hlwb.
Kev noj tshuaj ntau dhau hle tuaj yeem ua rau poob qab zib sai. Nrog cov ntshav qog ntshav qab zib tsawg, tus neeg yuav tsum haus cov khoom muaj cov carbohydrates ntau.
Hauv kev mob nyhav rau tus neeg mob, tshwj xeeb yog nws tsis nco qab lawm, yuav tsum tau mus pw hauv tsev kho mob sai. Tus kws kho mob txhaj cov tshuaj qabzib lossis qabzib rau hauv qab daim tawv lossis hauv cov leeg.
Thaum tus neeg mob rov qab, nws tau muab ib qho qab zib los yog chocolate ua los tiv thaiv nws cov piam thaj kom pheej rov qab los.
Sib cuam tshuam nrog lwm txoj kev
Thaum ua txoj kev kho cov nyom raws li kev siv ntau yam tshuaj, cov tshuaj insulin tuaj yeem txo qis thiab nce ntxiv.
Muaj cov npe tshuaj uas muaj feem cuam tshuam rau qhov xav tau ntawm tib neeg lub cev hauv cov piam thaj hauv kev noj qab haus huv.
Raug cov tshuaj insulin tuaj yeem txo los ntawm:
- glucocorticosteroids;
- iodine-muaj cov thyroid hormones;
- tshuaj tiv thaiv rau kev siv ntawm qhov ncauj;
- thiazide diuretics;
- tricyclic cov tshuaj tiv thaiv kab mob;
- somatropin, heparin thiab sympathomimetics;
- calcium antagonists;
- clonidine, diazoxide thiab phenytoin;
- morphine, danazole thiab nicotine.
Ntxiv dag zog rau cov nyhuv qis qis ntawm cov roj ntsha insulin tshwm sim thaum noj:
- ATP inhibitors;
- MAO inhibitors;
- hypoglycemic tshuaj rau lub qhov ncauj;
- carbonic anhydrase inhibitors;
- anabolic steroids, bromocriptine;
- sulfonamides, tetracyclines, ketoconazole;
- clofibrate, mebendazole, theophylline, pyridoxine;
- tsis xaiv khoom beta-blockers;
- tshuaj ntawm lithium, fenfluramine;
- dej cawv thiab npaj nrog cawv.
Salicylates, reserpins, lanreotides thiab octreotides tuaj yeem muaj cov txiaj ntsig sib txawv ntawm qhov xav tau rau lub cev, nce lossis txo nws. Siv cov beta-blockers obscures cov tsos mob ntawm kev mob ntshav qab zib. Cov tshuaj insulin yuav tsum tsis txhob noj nrog tshuaj, suav nrog thiols lossis sulfites, txij li lawv rhuav tshem nws cov qauv.
Qhov tseem tsis tuaj yeem siv nrog kev daws teeb meem.
Nqi, tshuaj xyuas, txhais tau tias zoo ib yam
Cov tshuaj Levemir flekspen, cov tshuaj tiv thaiv uas yog Detemir insulin, raug muag hauv khw muag tshuaj thiab khw muag tshuaj online.
Koj tuaj yeem yuav cov tshuaj tsuas yog nrog kws kho mob lub hwj tshuaj.
Cov tshuaj yog kim heev, nws cov nqi sib txawv ntawm 2560 txog 2900 Lavxias rubles. Hauv qhov no, tsis yog txhua tus neeg mob tuaj yeem them nws.
Txawm li cas los xij, kev txheeb xyuas ntawm Detemir insulin yog qhov zoo. Ntau tus neeg mob ntshav qab zib uas tau txhaj nrog humanoid hormone tau sau tseg txog cov txiaj ntsig no:
- maj mam txo cov ntshav qab zib;
- tswj qhov kev cuam tshuam ntawm cov tshuaj rau ib hnub;
- yooj yim ntawm kev siv syringe cwjmem;
- tsis tshua muaj tshwm sim ntawm cov nyom tshwm sim;
- tswj qhov hnyav ntawm cov ntshav qab zib nyob rau tib theem.
Tau txais ib qho piam thaj ib qho tseem ceeb tsuas yog ua tau los ntawm kev ua raws li txhua txoj cai ntawm kev kho mob ntshav qab zib. Qhov no tsis tsuas yog txhaj tshuaj insulin, tab sis kuj tawm dag zog lub cev kev tawm dag zog, qee qhov kev txwv kev noj zaub mov thiab tswj ntshav qab zib kom zoo. Ua raws li cov tshuaj kho tau yog qhov tseem ceeb, txij li qhov pib ntawm kev mob ntshav qab zib, nrog rau nws qhov tshwm sim hnyav, tsis suav nrog.
Yog tias cov tshuaj rau qee qhov tsis haum rau tus neeg mob, tus kws kho mob tuaj yeem sau tshuaj rau lwm txoj hauv kev ntxiv. Piv txwv, insulin Isofan, uas yog ib qho piv txwv ntawm tib neeg cov tshuaj hormones, uas yog tsim los ntawm kev tsim kho caj ces. Isofan tsis yog siv tsis yog mob ntshav qab zib mellitus ntawm thawj thiab thib ob hom, tab sis kuj tseem nyob hauv nws daim ntawv taw (hauv cov poj niam cev xeeb tub), intercurrent pathologies, ntxiv rau kev phais mob.
Nws lub sijhawm ntawm qhov kev txiav txim siab yog tsawg dua li ntawm Detemir insulin, txawm li cas los xij, Isofan tseem muaj qhov ua tau zoo hypoglycemic zoo. Nws muaj yuav luag tib qhov kev phiv tshuaj, lwm yam tshuaj tuaj yeem cuam tshuam nws cov hauj lwm zoo. Isofan tivthaiv muaj nyob hauv ntau cov tshuaj, piv txwv li, Humulin, Rinsulin, Pensulin, Gansulin N, Biosulin N, Insuran, Protafan thiab lwm yam.
Nrog rau kev siv txoj cai ntawm insulin Detemir, koj tuaj yeem tshem tawm cov tsos mob ntshav qab zib. Nws cov analogues, kev npaj kom muaj cov tshuaj insulin Isofan, yuav pab tau thaum kev siv cov tshuaj tsis txwv. Yuav ua li cas nws ua haujlwm thiab vim li cas koj xav tau insulin - hauv video hauv kab lus no.
