Nws ntseeg tau tias siv cov tshuaj Verapamil, ntshav qab zib hom 1 tuaj yeem kho tau. Raws li qhov no tsuas tuaj yeem twv tau, tab sis nws txoj hauv kev kho tau zoo hauv kev kho cov kab mob ntawm cov kab mob ntawm cov hlab plawv tau raug pov thawj los ntawm ntau cov kev tshawb fawb.
Verapamil yog ib qho tshuaj siv thaum kho thiab tiv thaiv kev ntxhov siab ntawm lub plawv. Nws cuam tshuam li cas rau cov piam thaj hauv ntshav qab zib?
Cia peb sim paub qhov no.
Cov ntaub ntawv siv tshuaj dav dav
Verapamil yog ib qho tshuaj hypotensive, antiarrhythmic thiab antianginal tshuaj. Nws yog rau pawg ntawm qeeb calcium calcium blockers.
Qhov kev txiav txim ntawm cov tshuaj yog los thaiv cov calcium calcium thiab txo cov transmembrane calcium tam sim no.
Nws yog tsim nyob rau hauv cov ntaub ntawv tsuas npaum li cas: ntsiav tshuaj, dragees, kev daws teeb meem rau kev lis ntshav thiab txhaj tshuaj.
Ib yam tshuaj tuaj yeem raug kho nyob rau hauv kev kho lossis tiv thaiv ntawm cov pathologies:
- kev ntaus lub siab tuaj;
- atrial fibrillation thiab viav vias;
- supraventricular ntxiv riam;
- paroxysmal supraventricular ticardia;
- ntshav siab;
- mob caj dab ntev tsis khov lossis tsis khov;
- vasospastic angina pectoris (txawv thiab Prinzmetal).
Cov nyhuv antiarrhythmic ntawm Verapamil yog muab los ntawm kev poob qis thiab txo qis hauv kev mob plawv, qhov txo qis ntawm lub tshuab automatism ntawm lub plawv mob, nrog rau kev ua kom tsis muaj zog ntawm sinoatrial thiab atrioventricular conduction. Raws li qhov tshwm sim ntawm kev cuam tshuam nrog rau cov tshuaj, cov hlab ntsha cov hlab ntsha ntawm lub plawv nthuav dav, vim cov ntshav tawm ntawm lub ntsej muag. Ntxiv rau, qhov kev xav tau oxygen yog qhov ua kom qis hauv lub siab.
Qee qhov kev thov tias verapamil inhibits qhov ua rau tus mob ntshav qab zib hom 1. Cov tshuaj tshem tawm ntau tshaj qhov hais qhia ntawm TXNIP protein, tiv thaiv beta hlwb los ntawm kev cuam tshuam tsis muaj zog hauv cov tshuaj tiv thaiv. Yog li, verapamil ua rau txo qis ntshav qab zib.
Hauv xyoo 2015, cov kev tshawb fawb tau tshawb xyuas txog qhov tshwm sim ntawm cov tshuaj hauv ntshav qab zib hom 1. Ua ntej no, cov txiaj ntsig ntawm kev sim hauv cov nas ua pov thawj tias Verapamil tiv thaiv kev tuag ntawm cov qe ntshav.
Cov lus tshaj tawm tau hais tias hauv cov neeg mob noj cov tshuaj, qib C-peptides ntau ntxiv thaum lub sijhawm, uas qhia tau txo qis ntshav qab zib.
Cov lus qhia rau kev siv tshuaj
Txhawm rau yuav cov tshuaj no, thawj qhov koj xav tau yog hu rau koj tus kws kho mob, uas yuav sau ntawv yuav tshuaj. Tom qab yuav Verapamil, tus neeg mob yuav tsum ua tib zoo nyeem cov lus qhia uas txuas nrog. Yog tias koj muaj lus nug txog kev siv tshuaj, koj yuav tsum sab laj nrog koj tus kws kho mob.
Verapamil hauv cov ntsiav tshuaj lossis dragees tau noj ntawm qhov ncauj thaum lossis tom qab noj mov nrog ib qho kua tsawg. Tus kws kho mob txiav txim siab noj ntau npaum li cas thiab sijhawm ntev npaum li cas ntawm kev kho, coj mus rau hauv tus account yam xws li qhov mob hnyav, tus mob ntawm tus neeg mob thiab nws tus yam ntxwv.
Txhawm rau tiv thaiv txoj kev loj hlob ntawm arrhythmias, angina pectoris thiab mob ntshav siab, verapamil yog siv los ntawm cov neeg laus 40-80 mg 3 lossis 4 zaug ib hnub. Tom qab qee lub sijhawm, qhov ntau npaum li cas tuaj yeem raug nce ntxiv rau 120-160 mg ib hnub. Qhov siab tshaj plaws yog 480 mg.
Txij li thaum verapamil tshem tawm ntawm lub cev ntawm tus neeg mob mob siab rau lub cev ntev txaus, kev kho mob pib nrog kev txhaj tshuaj tsawg kawg. Qhov siab kawg txhua hnub noj tshuaj yuav tsum tsis pub tshaj 120 mg.
Cov tshuaj yuav tsum muab tso kom deb ntawm cov menyuam yaus hauv ib qho chaw tiv thaiv los ntawm ya raws.
Qhov chaw cia khoom kub yuav tsum tsis txhob siab tshaj 25 degrees Celsius, thiab txee lub neej yog 3 xyoos.
Cov tshuaj tiv thaiv thiab ua kom raug mob
Hmoov tsis, cov tshuaj tsis muaj mob txaus siv tsis muaj. Tib yam siv rau yeeb tshuaj Verapamil.
Tus neeg mob yuav tsum tsis txhob muab ib qho dab tsi tshem tawm ntawm tus kws kho mob. Nws yuav tsum paub txog txhua yam kabmob sib kis txhawm rau kom zam dhau qhov tsis zoo thaum siv tshuaj.
Kev siv verapamil yog txwv tsis pub yog tias tus neeg mob txom nyem los ntawm ntau tus kab mob.
Cov kab mob uas siv tshuaj tsis raug txwv:
- Mob plawv tsis ua hauj lwm (2-3 theem).
- Kev mob siab rau bradycardia (mob tsis zoo sinus atherosclerosis).
- Synotrial thaiv.
- Mob sinus syndrome.
- Cardiogenic poob siab (tshwj tsis yog tshwm sim los ntawm arrhythmia).
- AV blockade ntawm qib 2 thiab 3 (tshwj tsis yog rau cov neeg mob uas ua kom tsis muaj zog).
- Mob lub plawv tsis ua hauj lwm.
- Wolff-Parkinson-Dawb Syndrome thiab Morgagni-Adams-Stokes.
Tsis tas li ntawd, cov tshuaj yeeb tshuaj tsis tuaj yeem siv thaum muaj hnub nyoog yau (txog 18 xyoo), nrog rau kev ua haujlwm tsis huv thiab kev siv tshuaj beta-blockers. Verapamil yog siv nrog kev ceev faj thaum lub siab ua haujlwm ntawm lub siab.
Siv cov tshuaj tsis zoo tuaj yeem ua rau txhim kho kev phiv tshuaj:
- cov cim ntawm lub plawv dhia;
- nce ntshav siab;
- kev tsim kho ntawm AV blockade;
- kev ua si nkhaus heev;
- lub plab zom mov;
- nce kev ua si ntawm hepatic transaminases;
- khaus tawv thiab ua pob;
- kev txhim kho ntawm peripheral puffiness;
- kiv taub hau thiab mob taub hau;
- kev nkees nkees thiab kev npau taws;
- nce poob siab excitability.
Raws li qhov tshaj tawm dhau los, kev siab tus neeg mob yuav tsis nco qab. Tsis tas li, nws yuav muaj kev mob ntsws o bradycardia, mob ntshav liab, thiab asystole. Txoj kev pheej hmoo ntawm kev txhim kho AV blockade tseem nce.
Txhawm rau tshem tawm cov tsos mob ntawm kev mob ntshav siab lossis ntshav hauv AV blockade, dopamine, isoproterenol, norepinephrine, thiab calcium gluconate yog muab tshuaj rau hauv cov leeg ntshav.
Ntxiv mus, tus txheej txheem hemodialysis nyob rau hauv cov ntaub ntawv no tsis muaj txiaj ntsig.
Cov hauj lwm zoo ntawm hom 1 ntshav qab zib
Yam 1 ntshav qab zib mellitus tshwm sim muaj txiaj ntsig ntawm qhov tshwm sim autoimmune hauv tib neeg lub cev. Nyob rau tib lub sijhawm, nws hu ua tus kabmob ntawm cov tub ntxhais hluas, vim tias feem ntau nws tshwm sim thaum hnub nyoog ntxov. Qhov kev nce qib ntawm cov pathology ua rau kev tuag ntawm beta hlwb ntawm islet apparatus thiab qhov tas ntawm insulin ntau lawm. Raws li qhov tshwm sim, tus neeg mob cov ntshav qab zib cov ntshav nce siab.
Qhov xwm txheej tseem ceeb rau kev kho mob zoo ntawm ntshav qab zib hom 1 yog kev kho tshuaj insulin. Txog tam sim no, cov tshuaj niaj hnub tsis tuaj yeem txhim kho cov tshuaj uas tshem tawm qhov mob tag nrho. Ntxiv mus, txhawm rau kom txo qis piam thaj, nws yuav tsum noj thiab ua si kom yog thaum muaj qee yam ntshav qab zib.
Yog lawm, yog tias tus mob ntshav qab zib muaj qhov mob plawv tsis zoo, nws tuaj yeem siv tau Verapamil, muaj kev pom zoo ua ntej nrog tus kws kho mob. Niaj hnub no, cov kws tshawb fawb thiab kws kho mob tau nug txog qhov ua haujlwm ntawm cov tshuaj rau cov ntshav qab zib kom qis.
Tam sim no, cov kev tshawb fawb txuas ntxiv tau coj ua ntsig txog kev kho mob nyhuv tshuaj. Lawv sim ua pov thawj lossis rov ua raws li cov kev ntseeg hauv qab no:
- Verapamil muaj peev xwm kho tau hom ntshav qab zib 1.
- Cov tshuaj tiv thaiv lub hlwb los ntawm kev laus.
- Verapamil tiv thaiv cov pob qij txha.
- Cov tshuaj tiv thaiv kev loj hlob ntawm kev mob qog noj ntshav.
Qhov tseeb tseem hais tias tus neeg mob uas muaj ntshav qab zib hom 1 yuav tsis tuaj yeem txo cov ntshav qab zib kom tsis txhob siv tshuaj muaj qab zib.
Kev siv tshuaj insulin yog ib txoj hauv kev los tshem tawm hyperglycemia.
Nqi, tshuaj xyuas thiab analogues
Verapamil kov nrog ntau cov kab mob ntawm cov hlab plawv. Txawm li cas los xij, nws txoj kev siv los tshem tawm cov tsos mob ntawm tus mob ntshav qab zib hom 1 tseem yog qhov teeb meem.
Txawm li cas los xij, kev siv tus kheej yog qhov tsis tsim nyog, koj yuav tsum muaj kev pom los ntawm koj tus kws kho mob.
Tus mob ntshav qab zib yuav tsum nco ntsoov tias kev kov yeej kev mob tsuas yog ua tau los ntawm cov tshuaj insulin xwb, kev noj zaub mov kom raug, ua lub neej nquag, thiab tswj glycemic tas li.
Verapamil tuaj yeem yuav tau ntawm txhua lub tsev muag tshuaj.
Tus nqi ntawm cov tshuaj Verapamil nyob ntawm nws daim ntawv tso tawm. Tus nqi ntawm cov khoom lag luam tshuaj, nyob ntawm daim ntawv tso tawm, yog:
- ntsiav tshuaj (40 mg 30 pieces) los ntawm 38 txog 57 rubles;
- dragees (40 mg 30 pieces) los ntawm 47 txog 53 rubles;
- ampoules (2.5mg / ml 2ml 10 daim) los ntawm 66 txog 78 rubles.
Txhua tus tuaj yeem ua tau yuav, vim tias tus nqi ntawm cov tshuaj tsawg. Kev txheeb xyuas ntawm ntau tus neeg mob qhia tias qhov ua tau zoo ntawm cov tshuaj. Qee tus txawm tias sau txog kev txo qis hauv cov ntshav qab zib, txawm hais tias qhov no muaj tseeb npaum li cas tsis tau paub. Nws feem ntau raug kho rau cov poj niam cev xeeb tub nrog rau Genipral. Nws yog tshuaj rau uterine hypertonicity thiab ua rau lub plawv dhia ceev, uas tshem tawm ua tsaug rau Verapamil.
Qee qhov xwm txheej, kev siv cov tshuaj yuav raug txwv. Tom qab ntawv tus kws kho mob sau ib qho kev kho zoo ib yam uas muaj cov nyhuv kho zoo sib xws. Hauv khw khw muag tshuaj, Verapamil yog sawv cev los ntawm ntau cov npe lag luam, piv txwv li, Verpamil, Verogalid, Lekoptin, Isoptin, Vero-Verapamil, Verogalid thiab lwm yam.
Txhawm rau kom txo qis cov piam thaj hauv hom ntshav qab zib hom 1, koj tuaj yeem siv cov tshuaj xws li Metformin 850 lossis 1000. Txawm li cas los xij, ua ntej siv, kev sab laj tshwj xeeb yuav tsum muaj.
Hauv qhov yeeb yaj kiab hauv tsab xov xwm no, Elena Malysheva tseem yuav qhia txuas ntxiv lub ntsiab lus ntawm Verapamil.
