Cov tshuaj uas muaj cov tshuaj tiv thaiv nquag - saxagliptin tau siv thaum kho mob hom 2 mob ntshav qab zib mellitus. Lawv tseem tuaj yeem ua ke nrog lwm cov tshuaj uas muaj suab thaj ua kom cov ntshav kho tau zoo dua. Kab lus no yuav pab koj paub txog cov khoom tseem ceeb ntawm cov tshuaj, qhia txog, contraindications, phiv tshuaj, tshuaj muaj saxagliptin, tshuaj xyuas cov neeg mob ntshav qab zib thiab cov tshuaj zoo sib xws.
Txog rau hnub no, ntshav qab zib hom 2 tau raug kho ua tsaug rau ntau yam: noj zaub mov zoo, ua kom tawm dag zog, soj ntsuam cov ntshav qab zib kom tas li. Qhov chaw hauv plawv hauv kev kho kab mob yog tshuaj yeeb tshuaj.
Kev siv Onglisa lossis Saxagliptin, Metformin ua ke muaj cov txiaj ntsig zoo ntawm cov piam thaj hauv tus neeg mob. Kev txheeb xyuas txog cov tshuaj no feem ntau zoo.
Lub tsuas yog drawback yog tus nqi siab ntawm cov tshuaj Ongliza thiab nws cov analogues. Txhawm rau kom paub tseeb tias qhov ua tau zoo tshaj plaws thiab kom tsis txhob muaj ntau yam teeb meem, cov tshuaj yuav tsum tau coj nruj raws li kev saib xyuas ntawm kws kho mob.
Cov cuab yeej ntawm cov tshuaj nquag
Saxagliptin yog ib qho kev xaiv tsim thim rov qab sib tw dipeptidyl peptidase-4 (DPP-4) inhibitor. Thaum lub sij hawm siv cov tshuaj rau hauv cov neeg mob uas muaj hom 2 mob ntshav qab zib mellitus, qhov kev ua si ntawm DPP-4 enzyme poob thaum nruab hnub.
Tom qab tus neeg mob noj qabzib, cov concentration ntawm glucagon yog qhov txo qis. Nyob rau tib lub sijhawm, muaj kev tso tawm ntawm qhov hormone - insulin los ntawm tus txiav, lossis ntau dua meej - nws cov beta hlwb. Txoj kev no pab txo cov ntshav qabzib hauv lub plab ib qho hauv tib neeg.
Cov tshuaj no cuam tshuam nrog ntau yam tshuaj hypoglycemic - metformin, glibenclamide, pioglitazone, ketoconazole, simvastatin lossis dithiazem. Tab sis kev siv ua ke nrog qee qhov tsim nyog ntawm CYP3A4 / 5 isoenzymes, piv txwv li, ketoconazole, itraconazole, indinavir thiab lwm tus, tuaj yeem txo cov txiaj ntsig kho kom zoo ntawm saxagliptin.
Hauv ntau qhov kev tshawb fawb, cov kws tshawb fawb tsis muaj peev xwm tshawb pom cov txiaj ntsig tshwj xeeb ntawm saxagliptin ntawm cov lipid profile. Thaum siv cov tshuaj yeeb yaj kiab no, tsis pom muaj qhov hnyav nce hauv ib qhov twg ntawm cov neeg kuaj mob tus mob ntshav qab zib hom 2 mob ntshav qab zib.
Nws yuav tsum raug sau tseg tias cov kws tshawb fawb tsis tau ua cov kev kawm cuam tshuam txog kev cuam tshuam ntawm cov tshuaj tiv thaiv hypoglycemic ntawm yam tseem ceeb xws li haus luam yeeb, cawv, zaub mov noj, thiab siv tshuaj ntsuab.
Yog li, cov neeg uas muaj tus cwj pwm tsis zoo thiab noj tshuaj ntuj yuav tsum coj cov tshuaj nrog kev ceev faj heev.
Cov lus qhia rau kev siv tshuaj
Cov tshuaj muaj txiaj ntsig uas muaj cov tshuaj nquag - saxagliptin yog Onglisa.
Nws muaj nyob rau hauv daim ntawv ntawm 5 mg ntsiav tshuaj. Ib pob muaj 30 daim.
Lawv tau noj tsis hais txog pluas noj, ntxuav nrog me me ntawm cov dej.
Cov cim tseem ceeb rau kev siv tshuaj Onglisa, nyob rau hauv uas saxagliptin yog qhov tseem ceeb tshuaj hypoglycemic, suav hais tias:
- Hom 2 mob ntshav qab zib mellitus, yog tias kev noj haus thiab kev tawm dag zog tsis tuaj yeem cuam tshuam qhov txo qis hauv cov piam thaj hauv ntshav, li kev kho mob monotherapy.
- Ua cov cuab yeej ntxiv rau metformin thaum pib theem ntawm kev kho mob txhawm rau txhim kho cov txheej txheem hypoglycemic.
- Ua ib qho kev ntxiv rau kev kho mob monotherapy nrog metformin, sulfonylureas, thiazolidinediones, yog tias nws tsis tuaj yeem tswj hwm tau qib qab zib kom txaus.
Ua ntej pib kev kho mob, cov lus qhia rau kev siv tshuaj Ongliz yuav tsum ua tib zoo kawm. Tsuas yog tus kws kho mob tau tuaj yeem sau tshuaj nrog cov tshuaj no, koj tuaj yeem tsis yuav nws yam tsis muaj tshuaj. Nrog rau cov tshuaj monotherapy lossis sib xyaw nrog lwm txoj kev, tus neeg mob noj tsis ntau tshaj 5 mg ntawm tshuaj Onglisa ib hnub. Thaum pib theem ntawm kev kho mob nrog saxagliptin, Metformin noj ib hnub ntawm 500 mg. Thaum tus neeg mob tau hnov qab tias nws yog ib qho tsim nyog kom haus ib ntsiav tshuaj ntawm Onglisa, qhov no yuav tsum tau ua tam sim ntawd. Rau qee pab pawg ntawm cov neeg mob, qhov kev noj tshuaj txhua hnub yuav raug txo kom tsawg dua 2.5 mg. Cov no yog, ua ntej txhua yam, cov neeg muaj mob hemodialysis thiab lub raum tsis ua haujlwm. Nyob rau tib lub sijhawm, Ongliz yuav tsum tau noj tsuas yog tom qab dhau tus txheej txheem hemodialysis.
Cov ntsiav tshuaj raug muab cia rau qhov tsis ncav cuag ntawm cov menyuam yaus ntawm chav tsev tsis tshaj 30C. Lub txee lub neej ntawm cov tshuaj yog 3 xyoos.
Cov kev thaiv tsis zoo thiab cov tshwm sim
Zoo li ntau lwm yam tshuaj, Ongliz tshuaj yuav raug txwv.
Tib lub sijhawm, Onglisa yog tus kws kho mob tau sau ntawv tshwj xeeb rau cov neeg mob raum tsis ua haujlwm, cov neeg laus thiab cov neeg mob noj sulfonylurea derivatives.
Yog tias tus neeg mob ua ke ob lub tshuaj - Onglizu thiab Metformin, nasopharyngitis, qhov mob ntawm txoj hlab ntaws los ntawm kev ua xua tuaj yeem tshwm sim, yuav tshwm sim. Nco ntsoov nug koj tus kws kho mob seb yuav siv Metformin nrog lwm cov tshuaj li cas.
Koj siv tsis tau cov tshuaj no rau tib neeg:
- hnub nyoog qis dua 18 xyoo;
- yam 1 mob ntshav qab zib mellitus;
- kev kho mob insulin thiab kev kho tshuaj;
- nrog galactose intolerance, lactase deficiency, congenital glucose-galactose malabsorption;
- nrog cov ketoacidosis uas mob ntshav qab zib;
- thaum cev xeeb tub thiab lactation;
- nrog rau tus kheej tsis kam rau cov tshuaj ntawm cov tshuaj.
Thaum lub sij hawm monotherapy, cov tshuaj yuav ua rau muaj kev phiv tshuaj nyob rau hauv tib neeg, xws li:
- cov kab mob ua pa siab;
- o ntawm cov mob txeeb zig;
- xeev siab thiab ntuav
- mob taub hau;
- sinusitis (kev hloov kho ntawm tus mob rhinitis);
- gastroenteritis (mob rau lub plab thiab cov hnyuv).
Cov lus qhia rau kev siv tsis qhia tias muaj cov tsos mob tshwm sim cuam tshuam nrog kev noj tshuaj ntau dhau. Tab sis yog tias nws tau tshwm sim, kev pom zoo tshwm sim kev kho mob pom zoo.
Ntxiv rau, cov tshuaj saxagliptin tuaj yeem raug muab tshem tawm uas siv cov txheej txheem hemodialysis.
Tus nqi thiab tshuaj tshuaj
Cov tshuaj Onglisa tuaj yeem muas tau tom txhua lub tsev muag tshuaj nrog cov tshuaj noj lossis xaj luam hauv Is Taws Nem. Txhawm rau ua qhov no, mus rau hauv online khw muag tshuaj lub vev xaib thiab ua raws cov lus qhia kom tso ib qho kev txiav txim. Txij li cov tshuaj tsim nyob rau hauv Tebchaws Asmeskas, nws tus nqi kuj nce siab. Tus nqi ntawm cov qis-txo cov tshuaj nyob ntawm 1890 txog 2045 rubles.
Kev txheeb xyuas ntawm feem ntau cov ntshav qab zib yog qhov txaus siab. Coob tus neeg mob noj cov tshuaj no txog nws cov txiaj ntsig hypoglycemic. Tom qab ib chav kawm ntawm kev noj tshuaj, ua raws li kev noj haus thiab ua kom lub cev tawm dag zog, lub sij hawm ntev dua li ib txwm ntawm cov ntshav qab zib raug pom. Cov neeg mob uas siv Ongliza txaus siab nrog txoj kev siv yooj yim ntawm cov tshuaj. Kev tshwm sim tsis zoo tau raug pom nyob rau hauv qee zaus. Qhov tsis zoo tshaj plaws ntawm cov tshuaj yog nws tus nqi siab, vim qhov tseeb tias nws yog lub tshuaj yeeb yaj kiab.
Tib lub sijhawm, muaj kev tshuaj xyuas cov tsav tsheb uas tsav tsheb uas cov tshuaj ua rau kiv taub hau.
Yog li, cov neeg cuam tshuam nrog kev tswj hwm ntawm kev thauj mus los, nws raug nquahu kom nres lawv cov kev ua haujlwm thaum kho lawv thiaj li zam dhau qhov tsis zoo.
Sau cov tshuaj uas zoo sib xws
Yog tias tus neeg mob raug txwv tsis pub siv Ongliza lossis nws muaj qee yam kev mob tshwm sim, tus kws kho mob koom nrog tuaj yeem kho txoj kev kho mob los ntawm kev sau ntawv rau lwm txoj kev kho zoo sib xws.
Onglisa tsis muaj analogues nyob hauv cov tshuaj nquag, tab sis raws li kev cuam tshuam rau tib neeg lub cev, muaj cov tshuaj:
- Januvia yog ib hom tshuaj uas ua rau cov ntshav qab zib tsawg nyob hauv cov ntshav. Kev tsim khoom hauv tebchaws yog Netherlands. Cov tshuaj no tuaj yeem siv nrog kev kho mob hlwb, nrog rau ua ke nrog lwm tus neeg sawv cev hypoglycemic xws li Metformin nrog kev noj haus tsis zoo thiab kev siv lub cev. Tsis zoo li Onglisa, Januvia muaj tsawg dua cov contraindications. Tus nqi nruab nrab yog 1670 rubles.
- Trazenta muaj cov tshuaj tseem ceeb linagliptin, uas cov qib ntshav qab zib kom zoo. Cov tshuaj no yog tsim nyob hauv Tebchaws Meskas. Kev kho mob hauv cov tshuaj no tsis muaj txiaj ntsig, cov tshuaj siv ua ke nrog lwm cov tshuaj qab zib (Metformin, insulin, sulfonylurea derivatives, Pioglitazone, thiab lwm yam). Txawm li cas los xij, cov tshuaj no tau pom tias muaj kev nyab xeeb tshaj plaws, vim tias nws siv tsis ua rau muaj kev phiv tshuaj. Tus nqi nruab nrab yog 1790 rubles.
- Nesina yog tshuaj rau glycemic tswj nyob rau hauv hom 2 mob ntshav qab zib. Cov chaw tsim tshuaj txog cov tshuaj no yog lub tuam txhab American pharmacological Takeda Pharmaceuticals. Tus neeg sawv cev hypoglycemic tseem siv nrog monotherapy thiab nrog kev kho mob ntxiv nrog rau lwm cov tshuaj. Ntau zaus, muaj kev phiv tshuaj los cuam tshuam nrog kev zom cov quav tshwm sim. Tus nqi nruab nrab hauv cov khw muag tshuaj yog 965 rubles.
- Galvus yog lwm txoj kev siv tshuaj tiv thaiv kab mob siab. Nws yog tsim los ntawm lub tuam txhab tshuaj Swiss. Cov tshuaj no tuaj yeem siv nrog kev kho mob insulin thiab ntau lwm yam tshuaj qab zib qis dua. Nws muaj cov neeg sib txuam ntau, tab sis cov xwm txheej ntawm qhov tshwm sim ntawm kev tsis zoo yog xyaum txo tus lej. Tus nqi nruab nrab yog 800 rubles.
Tsis tas li, cov neeg mob ntshav qab zib feem ntau tau siv tshuaj Metformin 850 lossis nrog ntau npaum ntawm 1000 mg.
Nws yuav tsum raug sau tseg tias tsis muaj ib qho yeeb tshuaj hais saum toj no tuaj yeem siv rau hauv menyuam yaus (txog 18 xyoo), vim tias lawv txoj kev kho rau hauv cov xyoo hluas no tseem tsis tau kawm. Txhua yam tshuaj yog kim thiab tsis yog txhua tus neeg mob tuaj yeem them taus.
Daim vis dis aus hauv tsab xov xwm no hais txog tshuaj txo suab thaj.
