Augmentin yog cov tshuaj sib xyaw ua ke siv los kho menyuam yaus thiab cov laus. Qhov zoo ntawm cov tshuaj yog qhov muaj peev xwm siv tau thaum yau.
Ath
Cov tshuaj tua kab mob no muaj nyob hauv qhov kev faib tawm qhov quav-tshuaj - tshuaj lom neeg muaj tshuaj (ATX). Cov tom kawg yog pom zoo los ntawm WHO. Cov Cai J01CR02.
Qhov zoo ntawm cov tshuaj yog qhov muaj peev xwm siv tau thaum yau.
Cov foos tso tawm thiab cov qauv ntawm Augmentin
Muaj 2 daim ntawv ntawm kev tso tawm tshuaj: cov ntsiav tshuaj thiab hmoov los ntawm qhov kev ncua raug npaj. Cov tshuaj tsis muaj nyob hauv cov kua txiv. Tsis zoo li Flemoxin Solutab, 2 lub tebchaw nquag tshwm sim hauv qhov kev npaj tam sim no: clavulanic acid thiab amoxicillin.
Ntsiav tshuaj
Cov ntsiav tshuaj nrog 125 mg ntawm clavulanic acid muaj puag ncig (oval) duab. Lawv yog cov dawb hauv cov xim nrog lub npe tshuaj hu ua Augmentin. Cov ntsiav tshuaj tau muab tso rau hauv hlwv ntawm 7 lossis 10 daim, duab los qhia thiab ntim khoom ua los ntawm ntawv ci. Cov khoom xyaw ntxiv suav nrog magnesium stearate, silicon dioxide, cellulose, thiab carboxymethyl hmoov txhuv nplej siab. Zaj duab xis membrane muaj macrogol, hypromellose thiab lwm yam tshuaj ntxiv rau.
Augmentin ntsiav tshuaj muab tso rau hauv hlwv ntawm 7 lossis 10 daim.
Hmoov
Feem ntau, hmoov yog tshuaj kho thaum kho. Nws yog dawb nrog lub aroma tshwj xeeb. Thaum tov nrog kua, ib qho dawb nag lossis daus tshwm. Lub Cheebtsam ntu ntawm cov hmoov yog succinic acid, aspartame, tsw zoo nkauj, hypromellose, pos hniav thiab silicon dioxide.
Tshuaj
Nws txhaj (rau hauv cov leeg lossis gluteus leeg) thaum tus neeg mob nyob rau hauv kev mob hnyav.
Mechanism ntawm kev ua
Cov tshuaj rhuav tshem cov kab mob gram-zoo thiab gram-tsis zoo. Nws muaj cov beta-lactamase inhibitor, uas ua rau kev rhuav tshem cov kab mob microbial uas ua yeeb yaj kiab rau kev siv tshuaj nrog lub nplhaib-lactam. Tag nrho cov no nce qhov kev ua tau zoo ntawm cov tshuaj.
Cov kab mob Gram-positive thiab gram-tsis zoo yog muaj rau Augumentin.
Cov hauv qab no yog raug rau Augmentin:
- xov noia;
- daim ntawv teev npe;
- causative tus neeg sawv cev ntawm anthrax;
- streptococci;
- staphylococci;
- tus neeg sawv cev ntawm tus mob hnoos qeev;
- Helicobacter pylori;
- moraxella;
- neysseries;
- causative tus neeg sawv cev ntawm borreliosis;
- treponema;
- leptospira;
- hemophilic cov ntoo;
- mob hnoos qhuav;
- gram-negative anaerobes (kab mob, kab mob fusobacteria, clostridia).
Intracellular parasites (chlamydia, mycoplasmas), yersinia, enterobacter, acinetobacteria, cytrobacter, serrations, morganella thiab legionella muaj tshuaj tiv thaiv cov tshuaj. Klebsiella, Proteus, Salmonella, Shigella, Escherichia coli, Enterococci, Corynebacteria thiab qee hom kabmob streptococci yuav kis tau tshuaj tiv thaiv.
Qhov tseem ceeb ntawm cov tshuaj tua kab mob (amoxicillin) yog cov tshuaj tua kab mob, uas yog, nws tua cov kab mob.
Cov Tshuaj Pharmacokinetics
Thaum noj, cov khoom tseem ceeb tau nrawm rau hauv cov hnyuv. Qhov siab tshaj plaws (nqus tau) raug pom thaum noj tshuaj thaum pib noj. Lub Cheebtsam muab cov protein sib txuas ua ke thiab muab faib thoob plaws lub cev. Clavulanate thiab amoxiclav pom muaj ntau hauv cov pob txha, cov leeg, cov leeg thiab cov plab hnyuv plab, thiab cov roj ntsha tso zis.
Cov ntsiab lus Augmentin tuaj yeem nkag rau hauv qhov tseeb ntawm lub cev, tsis tas yuav ua rau cov mis tsis ua haujlwm tsis zoo. Cov tshuaj nquag kis mus rau cov qog thiab lub mis mis. Txog li 25% ntawm kev haus tshuaj muaj yees yog kho los ntawm ob lub raum. Clavulanic acid tau nrawm rau cov roj ntsha thiab cov quav tawm los ntawm lub raum, quav thiab cua los ntawm lub ntsws. Amoxicillin tsuas yog tso zis nkaus xwb.
Cov ntsiab lus Augmentin tuaj yeem nkag rau hauv qhov tseeb ntawm lub cev, tsis tas yuav ua rau cov mis tsis ua haujlwm tsis zoo.
Kev ntsuas rau siv
Cov kab mob uas kho los ntawm Augmentin:
- Kev kis mob ntawm daim tawv nqaij thiab cov nqaij mos. Qhov no suav nrog streptoderma thiab staphyloderma (folliculitis, ecthyma, impetigo, ostiofolliculitis, hydradenitis, rwj, carbuncles).
- Kev kis mob ntawm tus mob ua pa sab hauv lub ntsws thiab lub ntsws (tonsillitis, kev puas tsuaj rau lub ntsws, mob ntsws, mob tonsillitis, mob pob ntseg, mob tawm pob, mob ntsws).
- Pathology ntawm cov genitourinary system (mob cystitis thiab mob ntsws sai, mob ntawm lub raum, mob rau lub raum, prostatitis, vulvovaginitis, endometritis, salpingoophoritis, prostatitis).
- Gonorrhea (mob sib kis los ntawm pawg STI).
- Osteomyelitis (suppurative inflammatory pob txha mob).
- Kab mob ntawm cov hniav thiab lub puab tsaig (mob qog nqaij hlav, mob ntu, mob txhaws ntawm qhov mob siab maxillary).
- Tej yam kev mob Septic.
- Tom qab kis tau tus kab mob.
- Kev ua mob ntawm tus mob peritoneum (peritonitis).
Nws tuaj yeem siv rau mob ntshav qab zib
Qhov muaj ntshav qab zib tsis yog qhov sib txuam rau txoj kev siv Augmentin, tab sis nws yuav tsum siv nrog ceev faj. Nws yog ib qho tsim nyog los tswj cov qib ntawm cov piam thaj hauv cov ntshav.
Cov neeg mob uas mob ntshav qab zib ntau nephropathy (mob raum) tsis yog cov kws kho mob sau tseg.
Cov Yuav Tsum Muaj
Contraindications yog:
- tshuaj intolerance (hypersensitivity);
- kev fab tshuaj rau beta-lactam antimicrobials;
- lub hnub nyoog ntawm cov neeg mob txog 12 xyoos thiab me me lub cev qhov hnyav (qis dua 40 kg rau cov ntsiav tshuaj ntawm 875, 250 thiab 500 mg);
- cov neeg mob hnub nyoog qis dua 3 hlis (rau hmoov 200 thiab 400 mg);
- raum tsis ua hauj lwm;
- phenylketonuria (rau hmoov).
Cov tshuaj tiv thaiv kab mob tau kho nrog kev ceev faj rau cov neeg muaj mob rau daim siab.
Yog tias tus neeg mob muaj lub siab ua rau lub siab, cov tshuaj kho nrog ceev faj.
Yuav noj li cas
Cov tshuaj yog qhov zoo dua los siv thaum pib noj mov, vim tias qhov no txo qhov kev pheej hmoo ntawm cov teebmeem tsis tuaj yeem ua. Augmentin yuav tsum noj ua ntej noj mov. Qhov ntau yam ntawm kev noj tshuaj yog 2-3 zaug ib hnub. Thaum kho cov menyuam mos, yuav tsum tau muab ib qho tshuaj suav los ntawm tus kws kho mob uas koom nrog. Cov koob tshuaj kuj tau muab kho rau hauv kev kho mob ntawm cov neeg laus uas lub raum lub siab tsis ua haujlwm. Hauv qhov no, kev pom kev ntshiab raug coj mus rau hauv tus account.
Thaum siv cov hmoov txhuam, qhov ncua cia 5 ml tau npaj. Qhov no ua tiav ua ntej noj mov. Cov dej rhaub ntawm chav sov yog ntxiv rau hauv lub thauv, tom qab uas nws tau shaken. Kev raug tshem tawm yuav tsum raug tso cai rau siv rau li 5 feeb, ntxiv ib zaug ntxiv cov dej mus rau ntawm qhov cim tseg. Tom qab tshee, cov tshuaj tuaj yeem daws qhov ncauj. Tom qab dilution, cov tshuaj yog khaws cia tsis pub dhau ib lub lim tiam hauv lub tub yees. Nws yuav tsum tsis txhob ua kom khov.
Pes tsawg hnub rau noj
Lub sijhawm kho yog nyob ntawm tus kabmob qis thiab thaj tsam li 5 txog 14 hnub.
Tom qab kev nrawm, qhov kev ua tiav tiav tau khaws cia hauv lub tub yees rau tsis pub ntau tshaj ib lim tiam.
Sab sij huam
Kev noj tshuaj yog feem ntau nrog cov mob tsis xav ua (phiv). Cov kev hloov pauv no tsis khov thiab ploj mus tom qab discontinuation ntawm kev kho mob.
CNS
Los ntawm lub hauv nruab nrab hauv lub paj hlwb tau muaj:
- mob taub hau
- Kiv taub hau
- nce kev ua si (tsis tshua pom);
- mob huam;
- kev pw tsaug zog;
- arousal
- kev hloov pauv tus cwj pwm.
Cov kev mob tshwm sim ntawm Augmentin los ntawm lub hauv nruab nrab cov hlab ntsha yog mob taub hau, kiv taub hau thiab pw tsaug zog.
Cov xwm txheej no thim rov qab thiab ua tau rau txhua ntu ntawm kev siv tshuaj tua kab mob.
Los ntawm cov mob hauv plab zom mov
Los ntawm sab hauv lub plab zom mov, cov kev xav tsis pom hauv qab no tau pom:
- ua txhaum ntawm cov quav ua raws plab;
- xeev siab (tshwm sim nrog kev siv tshuaj ntau heev);
- ntuav
- rho tawm ntawm cov hniav txha hniav laus.
Qee zaum colitis (mob rau ntawm lub plab hnyuv loj), gastritis (mob hauv plab) thiab stomatitis (mob rau ntawm lub qhov ncauj mucosa) loj hlob.
Cov kev mob tshwm sim no tuaj yeem zam dhau yog tias koj noj tshuaj tua kab mob raws li cov lus qhia.
Cov kab mob zis
Cov kabmob no muaj tsawg kawg. Qee lub sij hawm muaj mob interstitial nephritis, hematuria (ib qho admixture ntawm cov ntshav hauv cov zis) thiab crystalluria (qhov tshwm sim ntawm cov ntsev nyob hauv cov zis).
Kev tiv thaiv kab mob
Nws tsis tshua muaj kev txom nyem thaum noj tshuaj tiv thaiv kab mob. Tej zaum muaj kev txhim kho ntawm cov mob hlwb (vim yog ua xua rau cov tshuaj), anaphylaxis, mob ntshav dej thiab mob vasculitis (mob vascular).
Daim tawv nqaij thiab qog ua pa
Qee zaum candidiasis ntawm daim tawv nqaij thiab mucous daim nyias nyias nthuav dav.
Ib qho ntawm cov kev mob tshwm sim ntawm cov tshuaj yog kev loj hlob ntawm candidiasis ntawm mucous daim nyias nyias.
Los ntawm cov ntshav thiab lymphatic system
Thaum siv cov tshuaj, qee zaum nws pom:
- ib qho kev txo qis hauv tag nrho cov qe ntshav dawb hauv cov ntshav (leukopenia);
- platelet txo;
- hemolytic anemia;
- thim rov qab agranulocytosis;
- lub sijhawm ntev ntawm cov ntshav coagulation sijhawm;
- los ntshav
- eosinophilia (tshaj li ntawm kev cai ntawm eosinophils hauv cov ntshav).
Daim siab thiab nplooj siab
Qee zaum, cov qe ntshav siab hauv cov ntshav ntawm cov neeg mob nce ntxiv. Tsis tshua muaj kev phiv tshuaj yog jaundice, mob siab (ua mob rau daim siab), muaj ntau ntawm bilirubin thiab alkaline phosphatase. Cov kev tsis zoo no feem ntau pom nyob hauv cov neeg laus.
Cov lus qhia tshwj xeeb
Thaum teem Augmentin, tus kws kho mob yuav tsum coj mus rau hauv tus account tsis tsuas yog kev ntsuas thiab sib kis, tab sis kuj pom zoo tshwj xeeb. Thaum coj kev kho mob, koj tsis tuaj yeem haus cov cawv haus cawv thiab pheej yig.
Thaum noj Augumentin, koj tuaj yeem tsis haus dej haus cawv ntau.
Siv thaum cev xeeb tub thiab lactation
Nws zoo dua tsis txhob siv tshuaj thaum nqa tus menyuam. Kev tshawb fawb zaws hais txog cov nyhuv ntawm kev loj hlob ntawm tus menyuam tseem tsis tau ua. Thaum kuaj cov tshuaj hauv cov tsiaj, tsis muaj teratogenic nyhuv ntawm cov tshuaj. Qhov tshuaj tiv thaiv kab mob tuaj yeem muab tso rau thaum pub niam mis. Yog tias tsis pom qhov cuam tshuam tshwm sim, tsum tsis kho.
Koob tshuaj rau cov me nyuam
Hmoov rau kev ncua kev kawm raug pom rau tus menyuam txog 12 xyoos. Nrog lub cev nyhav txog 40 kg lossis ntau dua, qhov ntau npaum qhov tsis txawv ntawm qhov ntawd rau cov laus. Kev kho mob ntawm cov menyuam mos los ntawm 3 hlis txog 12 xyoos tuaj yeem nqa nrog kev ncua 4: 1 (3 zaug hauv ib hnub) thiab ncua hauv qhov sib piv ntawm 7: 1 (2 zaug hauv ib hnub). Thaum nyob ntawm lub tshuab raj tshuaj hemodialysis, cov tshuaj yuav tau noj 1 zaug ib hnub.
Siv rau lub sijhawm qub
Koob tshuaj hloov kho yog nqa tawm nrog lub raum pathology.
Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo
Thaum kho, kev kuaj mob lub siab ua haujlwm (kuaj ntshav biochemical).
Thaum kho nrog Augumentin, tus neeg mob lub siab tseem ceeb.
Cov neeg mob uas lub raum tsis ua hauj lwm zoo
Cov ntsiav tshuaj ntawm koob tshuaj 1000 mg (rau cov tshuaj yeeb dej caw) tsuas yog siv nrog cov zis creatinine tshem tawm ntau dua 30 ml / min. Kev txhaj tshuaj yog qhov zoo dua.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tua kab mob tuaj yeem ua rau kiv taub hau, yog li rau lub sijhawm rau kev kho mob koj yuav tsum tsis kam ua haujlwm nrog cov cuab yeej thiab tsav tsheb.
Noj ntau dhau
Cov cim qhia ntawm kev siv ntau tshaj ntawm Augmentin yog:
- mob plab tsis ua hauj lwm (mob plab, tsam plab, raws plab, xeev siab, ntuav);
- cov tsos mob ntawm lub cev qhuav dej (pallor ntawm daim tawv nqaij, qeeb plawv dhia, nkees);
- cramps
- cov cim ntawm lub raum puas.
Hauv koob tshuaj ntawm 1000 mg, kev txhaj tshuaj ntawm cov tshuaj yog zoo dua.
Kev pab muaj nyob rau hauv kev txiav tawm cov tshuaj, siv cov tshuaj tsis haum tshuaj, kho kev kho mob, noj sorbents, ntxuav lub plab thiab ntxuav cov ntshav nrog hemodialysis.
Kev cuam tshuam nrog lwm yam tshuaj
Nws tsis pom zoo kom siv kev sib xyaw ntawm amoxicillin nrog clavulanic acid thiab probenecid tib lub sijhawm. Thaum ua ke nrog allopurinol, kev ua xua feem ntau tshwm sim. Nrog rau siv txia ntawm cov tshuaj tiv thaiv penicillin nrog methotrexate, qhov mob toxicity ntawm tom qab nce ntxiv.
Analogs
Ib qho kev sib xyaw zoo sib xws nrog Augmentin yog tshuaj Amoxiclav. Los ntawm cov twj ntawm kev ua, Suprax ze rau cov tshuaj tua kab mob. Qhov no yog tus sawv cev ntawm ib pawg ntawm cephalosporins. Cov tshuaj phiv yog cefixime. Cov tshuaj muaj nyob hauv daim ntawv ntawm cov tsiav tshuaj thiab granules.
Cia rau cov mob ntawm cov tshuaj Augmentin
Cia kub - tsawg dua + 25ºC. Khaws cov tshuaj hauv qhov chaw qhuav rau cov menyuam yaus siv tsis tau. Qhov kev ncua yog muab cia rau hauv tub yees ntawm qhov kub ntawm +2 txog + 8ºC.
Cov tshuaj tua kab mob tsuas yog muab tshuaj nkaus xwb.
Hnub tas sij hawm
Cov hmoov tsis tau qhib rau hauv 3 xyoos. Lub txee lub neej ntawm cov ntsiav tshuaj yog 2 thiab 3 xyoos, nyob ntawm cov ntsiab lus ntawm cov tshuaj nquag.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj tua kab mob tsuas yog muab tshuaj nkaus xwb.
Augmentin Nqe
Tus nqi nruab nrab ntawm cov tshuaj hauv cov khw muag tshuaj yog 250-300 rubles.
Kev txheeb xyuas txog Augmentin
Cyril, hnub nyoog 35 xyoo, Perm: “Tsis ntev los no, thaum tshuaj txog qhov mob tso zis los ntawm qhov zis, tau pom muaj tus kab mob gonorrhea.
Elena, 22 xyoo, Moscow: "Tom qab yug me nyuam nyuaj, sepsis tau tsim. Cov kws kho mob txhaj tshuaj tua kab mob raws li amoxicillin thiab clavulanic acid. Tam sim no kuv xav zoo."
Alexander, hnub nyoog 43 xyoo, Nizhny Novgorod: "Tau ob peb lub lis piam dhau los kuv tau mob pyelonephritis. Kuv txhawj xeeb txog kev mob nraub qaum thiab kub taub hau. Tus kws kho mob hais kom kuv mus kho nrog Augmentin. Tom qab ob peb hnub kuv zoo tu."
