Clindamycin yog ib hom tshuaj tua kab mob nrog rau kev ua kom haum rau txoj haujlwm, uas zwm rau pawg lincosamides. Nws yog siv rau cov kab mob rau cov laus hauv cov laus thiab menyuam yaus. Cov tshuaj tsis muaj txiaj ntsig rau kis kab mob.
Lub npe thoob ntiaj teb
Lub npe Latin rau cov tshuaj tua kab mob yog Clindamycin.
Ath
Tus lej rau ATX (kev sib cais ntawm lub cev thiab tshuaj siv tshuaj) ntawm cov tshuaj yog D10AF51. Pawg - D10AF.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog ua hauv gelatin tsiav tshuaj ntawm 150 mg, hauv daim ntawv ntawm lub qab zib, qhov kom pab rau kev nkag mus rau hauv qhov chaw mos (Clindacin) thiab ib qho kev daws teeb meem hauv ampoules ntawm 300 mg.
Cov tshuaj tua kab mob muaj nyob rau hauv daim ntawv ntawm cov ntshiab, tsis muaj xim lossis daj me ntsis kev daws.
Tshuaj
Cov tshuaj tua kab mob muaj nyob rau hauv daim ntawv ntawm cov ntshiab, tsis muaj xim lossis daj me ntsis kev daws. Hauv cov tshuaj ua tiav, nws tau nthuav tawm hauv daim ntawv ntawm phosphate. Tus nqi ntawm cov khoom xyaw nquag hauv 1 ml ntawm kev daws yog 150 mg. Ib qho sib ntxiv ntawm kev daws yog disodium edetate, cawv thiab dej. Cov tshuaj tau muab tso rau hauv 2 ml ampoules, uas tau muab ntim rau hauv lub thawv nrog lub hlwb lossis ntim khoom ntawm cardboard.
Cov tshuaj ntsiav
Cov tshuaj tua kab mob ua ke yog qhov loj me 1, nrog cov ntaub ntawv ntshav thiab ib lub kaus mom liab. Cov ntsiab lus yog hmoov dawb dawb. Cov tshuaj tua kab mob hauv cov tshuaj ntsiav yog nthuav tawm hauv daim ntawv ntawm hydrochloride. Lub ntu sib xyaw ntawm cov tshuaj yog: lactose, talc, magnesium stearate thiab pob kws hmoov txhuv nplej siab. Lub hau muaj cov titanium dioxide, quinoline daj thiab liab zas xim Ponceau 4R. Cov ntaub ntawv muaj cov nkaws, azurobin thiab zas dub. Hauv tshuaj ntsiav yog 150 mg tshuaj tua kab mob.
Antibiotic capsules yog qhov loj me 1. Hauv tshuaj ntsiav yog 150 mg tshuaj tua kab mob.
Cov tswm ciab
Cov tshuaj tua kab mob yog siv rau hauv qhov chaw mos ua kom muaj lub thooj voos kheej kheej. Xim - los ntawm dawb mus rau daj me ntsis. Tsis muaj kev suav nrog ntawm qhov ntev ua ntu ntawm cov khoom ntu. Cov tshuaj nquag hauv tswm ciab yog nthuav tawm hauv daim ntawv ntawm ntsev. Ntu ntu yog glycerides ib nrab hluavtaws. Hauv 1 lub tshuaj tiv thaiv kab mob yog 100 mg ntawm cov tshuaj tua kab mob.
Tshuaj pleev
Cov tshuaj tua kab mob tsis muaj nyob hauv daim ntawv pleev pleev, tab sis siv tshuaj pleev ib ce thiab 2% ntawm lub paum dawb. Lub Cheebtsam ntawm cov tshuaj yog: sodium benzoate, cov roj taum castor, polyethylene oxide thiab propylene glycol. Cov nplaum ua rau hauv lub raj xa dej. Ib koob tshuaj (5 g) muaj 100 mg ntawm tshuaj tua kab mob.
Cov tshuaj tua kab mob yog siv los ua cov kua pleev thiab ua kua pleev ntshav dawb 2%.
Pharmacological kev txiav txim
Cov tshuaj tua kab mob no ua rau ntau yam kab mob me me. Nws siv tau los tiv thaiv cov kab mob uas tsis ua thiab tsis stain siv txoj kev Gram. Cov tshuaj muaj cov kab mob bacteriostatic, uas yog, nws inhibits kev loj hlob thiab rov ua dua ntawm cov microbes hauv cov ntaub so ntswg. Tus txheej txheem ntawm cov tshuaj tua kab mob ua rau cuam tshuam nrog kev tsim cov protein tsis zoo.
Staphylococci (suav nrog cov mob epidermal), streptococci, enterococci, peptococci, peptostreptococci, ua rau tus neeg sawv cev ntawm tus mob botulism, bacteroids, mycoplasmas, ureaplasmas, bacilli thiab anaerobes uas tsis tuaj yeem ua rau cov tshuaj pleev zoo rau qhov tshuaj. Cov tshuaj no cim tau ntawm lincomycin hauv nws txoj kev kho mob.
Cov Tshuaj Pharmacokinetics
Qhov kev nqus ntawm cov tshuaj hauv plab thiab cov hnyuv tshwm sim sai thiab tag nrho. Kev noj kom qeeb (nqus tau). Cov tshuaj yooj yim nkag mus thiab faib rau hauv cov ntaub so ntswg. Ib qho me me ntawm cov tshuaj tua kab mob nkag mus rau hauv lub hlwb.
Cov tshuaj tua kab mob nkag mus rau hauv cov hlab ntshav sai tshaj plaws thaum yuav muab tshuaj rau txoj leeg ntshav.
Qhov tshuaj ntau tshaj plaws hauv cov ntshav tom qab 1 teev (thaum siv tshuaj ntsiav), tom qab 1 teev (thaum txhaj rau hauv cov nqaij gluteus) hauv menyuam yaus thiab tom qab 3 teev rau cov neeg laus. Cov tshuaj tua kab mob nkag mus rau hauv cov hlab ntshav sai tshaj plaws thaum yuav muab tshuaj rau txoj leeg ntshav. Cov tshuaj nyob rau hauv lub tshuaj mloog zoo nyob rau hauv cov ntshav rau 8-12 teev. Hauv daim siab ua haujlwm, cov tshuaj yog metabolized. Cov tshuaj tau tawm los ntawm lub raum nrog tso zis thiab hnyuv nrog rau quav.
Kev ntsuas rau siv
Cov kab mob uas siv tshuaj tuaj yeem sau tseg yog:
- Kev kis mob rau cov kabmob ENT (mob rau pharynx, larynx, pob ntseg, paranasal sinuses, ntsws, ntsws, ua pa), ua pa ntawm lub ntsws.
- Caws pliav kub taub hau.
- Mob ncauj plab.
- Cov kab mob ntawm cov kabmob genitourinary (ua mob rau lub tsev menyuam, vulvovaginitis, colpitis, salpingoophoritis, chlamydia).
- Staphyloderma, pyoderma, qog ntshav, mob peritonitis.
- Septicemia (ntshav lom tsis muaj purulent rau hauv nruab nrog cev).
- Purulent o ntawm cov pob txha pob txha (osteomyelitis).
- Cov kab mob endocarditis (mob rau sab hauv ob sab phlu plawv nrog lub valve puas).
Cov tshuaj muaj peev xwm raug txiav txim siab tiv thaiv kev raug mob rau kev raug mob thiab ua paug ntawm cov hnyuv phab ntsa. Hauv qhov xwm txheej no, qhov muaj siab yog muab rau cov tshuaj txhaj rau hauv qhov nqaij lossis leeg ntshav.
Cov Yuav Tsum Muaj
Cov lus hauv qab no contraindications rau kev siv ntawm cov tshuaj yog raws cov lus qhia:
- myasthenia gravis (mob leeg tsis muaj zog);
- kev fab tshuaj rau clindamycin thiab lincomycin npaj;
- hawb pob
- ulcerative daim ntawv ntawm colitis (mob ntawm cov hnyuv);
- cev xeeb tub (cream yog kev nyab xeeb hauv lub thib 2 thiab thib 3 txiav plaub hau);
- lactation lub sijhawm;
- hnub nyoog txog li 3 xyoos (rau kev daws teeb meem);
- hnub nyoog txog 8 xyoo lossis me nyuam qhov hnyav dua 25 kg (rau tsiav tshuaj).
Nrog kev ceev faj, koj yuav tsum tau noj tshuaj rau cov neeg laus thiab cov neeg.
Nrog kev ceev faj, koj yuav tsum tau noj cov tshuaj rau cov neeg laus thiab cov neeg mob raum thiab mob pob txha.
Yuav noj li cas
Cov menyuam yaus hnub nyoog tshaj 15 xyoos thiab cov neeg laus raug pom zoo kom noj tshuaj ntsiav 1 zaug hauv thaj tsam li 6 teev. Thaum muaj mob hnyav, kws kho mob yuav ua tau kom muab tshuaj ntau ntxiv rau. Kev txhaj tshuaj yuav tsum tau ua ob zaug ib hnub (2 zaug 300 mg). Hauv kev kho cov neeg mob hnub nyoog laus dua 3 xyoos, kev noj tshuaj yog 15-25 mg / kg / hnub.
Nrog lub siab thiab lub raum tsis ua hauj lwm zoo, nrog rau cov kis loj (8 teev lossis ntau teev), tsis tas yuav hloov kho koob tshuaj.
Noj cov tshuaj rau ntshav qab zib
Hauv cov kab mob ntshav qab zib mellitus, cov tshuaj tua kab mob yog siv ob qho tib si hauv kev kho mob hauv qhov ncauj, thiab nyob rau hauv daim ntawv ntawm cov tshuaj tiv thaiv rau intravaginal tswj hwm thiab kev daws teeb meem. Thaum kho, nws pom zoo kom tswj ntshav qab zib.
Sab sij huam
Feem ntau, lawv thim rov qab thiab ploj mus thaum kho tsis tau lawm.
Hauv cov kab mob ntshav qab zib mellitus, cov tshuaj tiv thaiv kab mob yog siv nyob rau hauv daim ntawv ntawm tus neeg sawv cev ntawm qhov ncauj.
Kev kho mob txoj hnyuv
Thaum siv clindamycin, cov hauv qab no yog qhov ua tau:
- dyspepsia (kem plab mus rau hauv daim ntawv ntawm zawv plab, xeev siab);
- cov cim ntawm kev mob ntawm txoj hlab pas (nyuaj nqos, kub siab, mob);
- yellowness ntawm daim tawv nqaij;
- ua kom ntau dua ntawm cov kab mob siab rau lub siab;
- kev nce siab ntawm daim siab enzymes hauv cov ntshav;
- muaj zog concentration ntawm bilirubin hauv cov ntshav;
- plab hnyuv dysbiosis.
Qee zaum cov neeg mob pseudomembranous mob plab.
Thaum siv cov tshuaj, dysbiosis yog ua tau.
Hematopoietic plab hnyuv siab raum
Ntawm ib feem ntawm cov ntshav thiab cov ntshav tsim cov kabmob, cov kev hloov hauv qab no yog ua tau:
- ib qho poob hauv cov qe ntshav dawb;
- neutrophil txo;
- agranulocytosis;
- platelet poob.
Los ntawm cov hlab plawv system
Yog tias cov tshuaj nkag mus rau hauv cov leeg sai heev, kiv taub hau, txo qis siab, cev qhuav dej thiab qaug zog yog qhov ua tau.
Los ntawm cov leeg musculoskeletal
Qee zaum, muaj kev tiv thaiv kev sib kis ntawm cov hlab ntsha mus rau cov leeg.
Kev ua xua
Cov kev tsis haum tshuaj ntawm no tau muaj:
- urticaria (ua pob khaus ua pob ntawm cov hlwv ntawm ntau qhov chaw ntawm lub cev);
- maculopapular pob;
- dermatitis;
- eosinophilia (nce theem ntawm eosinophils hauv cov ntshav);
- anaphylaxis (kev poob siab, Quincke's edema).
Kev tsis haum tshuaj tiv thaiv muaj nyob rau hauv daim ntawv ntawm urticaria.
Cov lus qhia tshwj xeeb
Yog hais tias pom muaj pseudomembranous mob plab, ion-txauv resins tau zoo. Nws yuav tsum nres tshuaj tua kab mob. Yog tias tsim nyog, ib cov tshuaj raws li metronidazole siv thiab kev kho mob infusion yog nqa tawm.
Cov lus qhia rau kev siv qhia tias thaum noj clindamycin, koj tsis tuaj yeem:
- siv cov tshuaj uas ua kom paug plab hnyuv;
- haus dej haus cawv;
- siv lwm yam khoom noj ntawm lub paum (rau cov tshuaj nplaum thiab cov tshuaj tiv thaiv).
Nrog rau kev siv ntev ntawm clindamycin, zoo li erythromycin, kev pheej hmoo ntawm kev ua kom muaj poov xab zoo li fungi thiab kev txhim kho ntawm candidiasis nce ntxiv.
Cawv tau zoo
Hais txog kev noj tshuaj txhua hnub, cov tshuaj no yuav tsum tsis txhob noj ib txhij nrog cawv.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Cov tshuaj tua kab mob tsis yog los ntawm kiv taub hau thiab txav mus los, yog li nws tsis cuam tshuam rau kev tswj hwm ntawm kev siv tshuab thiab tsav tsheb.
Hais txog kev noj tshuaj txhua hnub, cov tshuaj no yuav tsum tsis txhob noj ib txhij nrog cawv.
Clindamycin rau menyuam yaus
Thaum muab tshuaj rau cov menyuam yaus, lawv lub hnub nyoog thiab lub cev hnyav txaus rau hauv tus lej. Cov tshuaj ntsiav tsis tuaj yeem siv ntev txog 8 xyoo, thiab kev daws teeb meem - ntev txog 3 xyoos.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj nyob rau hauv daim ntawv ntawm tov thiab tsiav tshuaj yog contraindicated thaum xeeb tub. Qhov paum yuav siv tsuas yog rau qhov ntsuas tau nruj me ntsis, thaum muaj txiaj ntsig zoo ntawm kev kho mob tshaj qhov muaj peev xwm yuav ua rau tus me nyuam hauv plab. Hauv thawj 3 lub hlis ntawm kev xeeb tub, tswm ciab tsis tau teev, vim hais tias thaum lub sijhawm no tseem ceeb cov kabmob ntawm tus menyuam.
Kev siv clindamycin nyob rau hauv daim ntawv ntawm lub qab zib thaum lub sijhawm lactation thiab kev pub niam mis yog qhov ua tau rau hauv kev suav daws qhov kev pheej hmoo.
Siv rau lub sijhawm qub
Cov tshuaj rau kev txhaj tshuaj thiab qhov ncauj siv thaum muaj hnub nyoog laus yuav tsum tau siv nrog kev ceev faj heev.
Noj ntau dhau
Yog tias qhov tshuaj txhua hnub ntawm cov tshuaj tau dhau siab, tom qab ntawd qhov nce ntawm qhov tsis xav tau ua tau. Kev noj ntau dhau tshwm sim nrog mob plab, kub ib ce thiab lwm yam tsos mob. Hemodialysis (ntshav ntxuav) hauv qhov no tsis muaj txiaj ntsig. Cov neeg mob yog cov kws kho mob tus yam ntxwv. Tsis muaj cov tshuaj antidote. Kev siv ntau tshaj ntawm cov tshuaj nyob rau hauv daim ntawv ntawm lub lee lossis cov tshuaj kom noj ntxiv yog qhov tsis tshua muaj.
Yog tias koj tshaj li qhov niaj hnub noj tshuaj, ces kub taub hau yuav tshwm sim.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj no ua rau txoj kev kho kom zoo rau cov tshuaj hauv qab no:
- aminoglycosides (streptomycin, gentamicin);
- rifamycin derivatives (rifampicin);
- leeg ua kom mob.
Siv tib lub sijhawm siv cov tshuaj tua kab mob no nrog cov tshuaj ampicillin, magnesia, derivatives ntawm barbituric acid thiab calcium gluconate yog txwv tsis pub. Clindamycin antagonists yog erythromycin thiab chloramphenicol.
Cov tshuaj tsis zoo nrog cov tshuaj tiv thaiv kab mob, npaj ntawm cov vitamins B thiab phenytoin. Yog tias koj siv cov tshuaj analgesics thaum sib ncag, ces ua pa tawm kom nres.
Analogs
Analogues ntawm cov tshuaj nyob rau hauv daim ntawv ntawm qab zib yog Dalacin, Klindes thiab Klindatsin. Txhua tus ntawm lawv qhia rau kev kuaj mob gynecological. Cov Gels rau kev siv sab nraud yog tsim Klindatop, Klenzit-S thiab Klindovit. Lawv yog yam tseem ceeb rau txoj kev kho pob txuv (pob ntxau).
Clindacin B Prolong Cream kuj tseem muaj. Nws txawv hauv qhov ntawd nws suav nrog cov tshuaj tua kabmob tab sis butoconazole nitrate, uas nthuav tawm cov xim ntawm cov tshuaj tua kabmob. Cov analogue ntawm clindamycin nyob rau hauv daim ntawv ntawm kev daws yog Zerkalin. Nws ntxuav cov tawv nqaij ntawm pob txuv thiab ntxau, zoo li tshuaj Adapalen.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj raug faib tawm los ntawm lub hwj tshuaj.
Clindamycin Nqe
Cov tshuaj ntsiav raug nqi los ntawm 170 rubles, thiab tus nqi ntawm kev daws teeb meem raws li cov tshuaj tua kab mob no yog ntau dua 600 rubles. Cov tshuaj nplaum nqi los ntawm 350 rubles., Cov tshuaj nyob rau hauv daim ntawv ntawm tswm ciab - ntau dua 500 rubles.
Cov kev mob cia ntawm cov tshuaj Clindamycin
Kev daws daws khaws cia rau hauv lub teeb tsaus nti ntawm qhov kub ntawm + 15 ... + 25ºC. Qhov chaw muab tshuaj tua kab mob yuav tsum tsis pub nkag rau cov menyuam yaus. Cov tshuaj yog los ntawm daim ntawv B. Cov tshuaj cia muaj nyob hauv tib qho chaw, chav yuav tsum qhuav. Thaum khaws cia cov qab zib, qhov kub yuav tsum tsis pub tshaj 20ºC. Clindamycin (Klindatop) gel yuav tsum tsis txhob khov thiab khaws cia rau hauv tub yees.
Hnub tas sij hawm
Cov tshuaj nplaum, txhaj tshuaj thiab gel yog khaws cia rau 2 xyoos. Lub txee lub neej ntawm tswm ciab thiab tsiav tshuaj yog 3 xyoos.
Clindamycin tshuaj xyuas los ntawm cov kws kho mob thiab cov neeg mob
Nikolai, hnub nyoog 22 xyoo, Moscow: "Acne tau ua rau ntau xyoo dhau los. Tus kws kho mob tau qhia cov tshuaj raws li clindamycin Klindatop. Hauv ob peb lub lis piam, kuv xav tias muaj kev txhim kho: nqaij tawv liab, khaus, thiab tawv nqaij tau zoo huv."
Svetlana, hnub nyoog 37 xyoo, Kaliningrad: "Tsis ntev los no peb pom tus kab mob vaginosis. Peb muaj kev txhawj xeeb txog kev tso tawm ntawm qhov chaw mos thiab lub cev tsis xwm yeem.
Julia, hnub nyoog 43 xyoo, Novosibirsk: "Tau ntau xyoo kuv tau sau cov tshuaj no rau kuv cov neeg mob hauv cov ntsiav tshuaj, tshwj xeeb yog rau cov kab mob ua pa. Ib qho tshuaj zoo heev."
