Rau lub hauv paus ntawm metformin hydrochloride, tsis tsuas yog cov qub Glucofage (330 rubles) yog tsim, tab sis kuj tseem muaj ntau yam analogues: Siofor (320 rubles), Metformin Teva (198 rubles), Metformin Canon (195 rubles). Yog tias tus kws kho mob sau tawm cov tshuaj noj raws li metformin, xav tias thov sau ntawv yuav tshuaj kom pheej yig thiab zoo Metformin Canon.
Cov tshuaj Glucofage ntawm chav kawm ntawm biguanides ntawm koob thib 3 yog qhov tshuaj tiv thaiv kab mob zoo uas normalize cov glycemic profile tsis muaj kev txhawb ntxiv ntawm tus txiav. Muaj tsawg kawg ntawm cov kev mob tshwm sim, ntawm cov uas tsis muaj ntshav qab zib, nws rov qab lipid metabolism, pab tswj lub cev hnyav.
Dosage Cov Ntawv thiab Sib Sau Metformin Canon
Cov tuam txhab tshuaj tua kab hauv tuam txhab Canonfarm ntau lawm tsim cov tshuaj nyob rau hauv daim ntawv puag ncig los yog oval convex ntsiav tshuaj hauv lub plhaub dawb. Ua raws li cov ntsiab lus ntawm metformin hydrochloride, ib hom tshuaj uas muaj tshuaj ntau npaum li 1000, 850, 500 mg tuaj yeem muas hauv lub tsev muag tshuaj network.
Ntawm Metformin Canon, tus nqi yuav yog nyob ntawm txoj cai kev lag luam ntawm lub tsev muag tshuaj thiab cov koob tshuaj:
- 30 pcs 850 mg txhua. - 88-90 rubles .;
- 30 pcs 1000 mg txhua - 108-138 rubles;
- 60 pcs. 500 mg - 146-160 rubles;
- 60 pcs. 850 mg txhua - 167-192 rubles;
- 60 pcs. 1000 mg txhua - 248-272 rubles.
Ntxiv nrog rau cov nquag tivthaiv, cov tshuaj sib xyaw ua ke tseem muaj cov tshuaj ntxiv rau hauv cov qauv ntawm cov hmoov txhuv nplej siab, primogel, povidone, sodium fumarate, talc. Lub plhaub yog ua los ntawm dawb opadra II, macrogol, polyvinyl cawv, titanium dioxide thiab talc.
Lub txee lub neej ntawm cov ntsiav tshuaj yog 2 xyoos, cov tshuaj tsis xav tau cov kev mob tshwj xeeb rau kev cia khoom.
Kws Tshuaj
Metformin Canon yog qhov tshuaj noj suab thaj qhov ncauj, yog tus sawv cev ntawm chav kawm biguanide nkaus xwb. Nrog rau qhov dhau ntawm cov piam thaj hauv cov ntshav, nws txo nws cov qib los ntawm inhibiting glucogenesis hauv daim siab, thaiv nws txoj kev nqus los ntawm cov hnyuv phab ntsa, ua kom muaj kev siv nws los ntawm cov nqaij mos, qhov twg nws hloov mus ua lub zog, ntau dua li cov rog, vim muaj kev cuam tshuam ntawm lub hom phiaj cell receptors rau insulin.
Txo cov tshuaj insulin kom tsawg dua rau cov nqaij sib kis, cov roj txheej yog qhov nyuaj dua rau kev zom zaub mov.
Metformin stimulates glycogen synthase thiab cell glycogenesis. Tsis zoo li npaj ntawm sulfanyl urea pab pawg, insulin ntau lawm tsis txhawb kev biagunids. Qhov no tsis tsim cov teeb meem ntxiv rau ntawm lub cev ua haujlwm tus kab mob hlwb thiab b-hlwb, tsis ua rau cov neeg mob ntshav qab zib hauv cov neeg noj qab haus huv uas siv cov metformin rau qhov kev poob phaus, kev tiv thaiv ntawm oncology thiab cov hlab plawv, lossis ua kom ntev lub neej hauv kev laus (tom qab 40 xyoo).
Ib qho mob tseem ceeb rau kev tswj hwm tag nrho ntawm glycemia hauv ntshav qab zib hom 2 yog qhov ib txwm ua rau lub cev hnyav. Tsis zoo li feem ntau cov tshuaj hypoglycemic, Metformin Canon yog qhov nruab nrab hauv kev sib raug zoo rau qhov hnyav, thiab nrog tas li siv nws txawm ua rau txo qis me ntsis.
Cov Tshuaj Pharmacokinetics
Qhov nqus ntawm metformin nyob rau hauv cov phab ntsa hauv lub plab yog nyob ntawm nws qhov kev puv: yog tias koj noj cov tshuaj ua ntej noj mov, qhov nqus tau yog 48-52%, thaum koj siv cov tshuaj thaum tib lub sijhawm ua zaub mov, txoj kev ua haujlwm poob qis thiab qhov ua haujlwm poob qis.
Kev saib xyuas qhov siab tshaj plaws ntawm biagunide (2 μg / l) yog pom tom qab 2-3 teev. Cov tshuaj sib kis tau sai sai los ntawm cov ntaub so ntswg, nrog lub cev txoj kev cia siab txog 60%. Cov tshuaj metabolite tsis tuaj rau hauv cov ntshav, tab sis nws nkag mus rau hauv cov ntshav liab. Feem ntau ntawm cov tshuaj accumulates nyob rau hauv lub raum, mob siab, thiab salivary qog. Thaum siv cov ntsiav tshuaj hnyav 850 mg, qhov ntim faib tawm yuav yog 296-1012 litres.
Metformin metabolites hauv lub cev tsis pom, ob lub raum tshem tawm nws hauv qhov tsis hloov pauv. Hauv cov neeg muaj cov metabolism hauv kev ua haujlwm, metformin tshem tawm yog nyob hauv thaj tsam ntawm 400 ml / min. Qhov kev tshem tawm ib nrab-lub neej yog 6.2 teev. Nrog lub raum pathologies, qhov ntsuas no nce, thiab nrog nws txoj kev pheej hmoo ntawm metformin, uas provokes lactic acidosis.
Cov lus qhia rau kev teem caij ntawm Metformin Canon
Metformin Canon tau sau tseg rau cov neeg mob ntshav qab zib nrog hom 2 yog tias hloov kho kev ua neej (kev noj zaub mov kom tsawg, ua kom lub cev zoo, tswj lub xeev) tsis muab glycemic tswj tiav.
Rau cov neeg mob nyhav dhau heev, metformin yog qhov kev xaiv zoo tshaj plaws. Cov tshuaj yog zoo ua ke nrog hypoglycemic tshuaj ntawm lwm pab pawg pharmacological, nyob rau hauv uas lub mechanism ntawm kev ua yog txawv los ntawm biguanides. Tej zaum yuav muaj kev kho mob nrog cov tshuaj insulin.
Cov tshuaj tseem tseem tau taw qhia txog kev kho mob ntshav qab zib hom 2 hauv cov menyuam hnub nyoog ntau dua 10 xyoo. Nws yog siv los ua thawj kab-tshuaj ib zaug lossis hauv kev sib xyaw nrog insulin.
Cov neeg tawm dag zog siv cov tshuaj no ua rau cov leeg qhuav, sim nrog poob thiab cov menyuam ntxhais, tab sis kev siv no tsuas yog lav yog tias qhov teebmeem ntawm qhov hnyav tshaj yog txuam nrog insulin tsis kam thiab cov teeb meem hauv lub cev hauv lub cev.
LEEJ TWG pom zoo cov tshuaj metformin rau cov neeg mob noj qab haus huv tom qab muaj hnub nyoog 40 xyoo ntawm 200 mg / m / hnub. kom kav ntev lub neej (kev tiv thaiv ntawm atherosclerosis, kev mob plawv ntshav, oncology).
Cov hau kev thov qauv
Cov ntsiav tshuaj yog qaug cawv tsis muaj kev sib tsoo, nrog rau dej, thaum lub sijhawm noj mov lossis tam sim ntawd. Tus kws kho mob rub tawm ib qho kev kho mob thiab koob tshuaj raws li kev soj ntsuam hauv chaw kuaj, theem ntawm tus kab mob, cov teeb meem tsis haum, tus neeg mob cov tshuaj tiv thaiv rau cov tshuaj metformin.
Cov Neeg Mob Ntshav Qab Zib
Cov tshuaj no yog siv rau kev kho mob monotherapy lossis hauv txoj kev kho mob nyuaj nrog rau lwm cov tshuaj tiv thaiv kab mob. Qhov pib txhaj ntawm Metformin Canon, raws li cov lus qhia rau kev siv, yog 1000-1500 mg / hnub. Yog tias koj faib cov kev cai niaj hnub los ntawm 2-3 zaug, koj tuaj yeem txo qhov yuav raug rau hauv daim ntawv ntawm kev ua rau tsis zoo. Tom qab 2 lub lis piam, yog hais tias lub cev tau yoog, tab sis glucometer tsis yog kev txhawb nqa, maj mam titration ntawm cov tshuaj yog tau.
Thaum hloov lwm cov tshuaj analogues, koj yuav tsum tsom rau qhov ntau npaum li cas ntawm cov tshuaj dhau los, nrog rau lub sijhawm lawv tshem tawm (daim ntawv ntev yuav tsum muaj qee lub sijhawm ncua).
Yog tias Metformin Canon tau tshaj tawm rau cov neeg mob ntshav qab zib ua ke nrog kev siv tshuaj insulin, qhov pib ntawm cov ntsiav tshuaj tsis pub tshaj ib chav nyob rau ib hnub ntawm kev noj tshuaj ntawm 1000 mg, 2-3 zaug / hnub. ntawm qhov ntau npaum ntawm 500-850 mg. Hauv qhov no, tus nqi insulin yog teev raws li cov yam ntxwv ntawm cov ntawv qhia zaub mov thiab kev qhia ntawm cov glucometer.
Kev saib xyuas cov menyuam yaus
Mob ntshav qab zib Hom 2 nyob rau cov menyuam yaus tsis yog qhov tshwm sim niaj hnub no, tshwj xeeb yog hauv cov tebchaws vam meej. Refined khoom noj khoom haus, lub cev tsis muaj zog, lub siab ntxhov siab tom qab tsim cov xwm txheej rau kev kis loj ntawm cov kabmob hauv menyuam yaus. Metformin Canon tau raug tshaj tawm rau cov menyuam yaus hnub nyoog tshaj 10 xyoo los ua thawj kab kev kho mob lossis muab tso ua ke nrog cov tshuaj insulin.
Cov koob tshuaj pib, kev qhia pom zoo kom xaiv qhov tsawg kawg nkaus - 500 mg / hnub. Ib lub ntsiav tshuaj muab rau tus me nyuam thaum yav tsaus ntuj, thaum noj hmo. Hauv ob lub lis piam, koj tuaj yeem soj ntsuam qhov tshwm sim ntawm kev kho thiab kho cov tshuaj, maj mam nqa nws mus rau qhov kev saib xyuas txij nkawm (1000-1500 mg / hnub) lossis ntau kawg (200 mg / hnub). Qhov kev siv tshuaj txhua hnub tau muab faib ua 2-3 koob tshuaj.
Cov Neeg Mob Cov Laus
Xyoo dhau los, hauv cov neeg mob ntshav qab zib nrog kev paub dhau los (thiab tsis yog xwb), lub peev xwm ntawm lub raum tsawg dua, yog li Metformin Canon tau raug tshuaj rau kev saib xyuas cov haujlwm ntawm lawv cov haujlwm txhua txhua rau lub hlis. Lub sijhawm kawm yog teem los ntawm kws kho mob, nws raug nquahu kom tswj lub sijhawm noj tshuaj rau hom mob ntshav qab zib thiab tsis txhob cuam tshuam kev kho mob yam tsis muaj kev pom zoo nrog tus kws kho mob endocrinologist.
Cov lus pom zoo ntxiv
Kev kho mob nrog Metformin Canon yuav tsum tau soj ntsuam txhua hnub ntawm cov glucometer thiab sau cov txiaj ntsig hauv qhov chaw muag mis nyuj ntawm tus mob ntshav qab zib. Ntxiv nrog rau kev yoo mov qab zib, nws yog ib qho tsim nyog yuav tau kuaj xyuas thiab xaib tom qab, 2 teev tom qab noj mov. Yog tias cov txiaj ntsig tau dhau dhau ntawm ib qho dhau los ntawm ntau tshaj 3 mmol / l, koj yuav tsum kho cov zaub mov noj.
Thaum sau daim ntawv tshuaj, ntshav qab zib tau ceeb toom txog qhov yuav tshwm sim tsis tuaj yeem ua tiav: nrog cov tsos mob ntawm xeev siab thiab ntuav, mob hauv plab plab, mob plab thiab ntse poob ntawm lub zog, koj yuav tsum txiav kev siv tshuaj thiab qhia qhov teeb meem rau tus kws kho mob.
Cov teeb meem me me tsis haum plab (tso quav thiab noj zaub mov) yuav ploj mus yam tsis muaj kev pab kho mob, tab sis qee qhov cim yuav yog thawj qhov hu ntawm kev tsim cov mob lactic acidosis.
Metformin, zoo ib yam li lwm yam tshuaj rau qhov ncauj hypoglycemic, raug tso tseg ob hnub ua ntej kev ua haujlwm, kev kuaj mob xoo hluav taws xob (suav nrog kev tiv thaiv tsis zoo, iv urography), uas siv iodine-based radiopaque cim. Rau lub sijhawm no, cov ntshav qab zib tau pauv mus rau insulin. Cov txheej txheem kev kho mob yav dhau los xa rov qab 2 hnub tom qab ua tiav ntawm cov txheej txheem, yog tias nws tus mob tsis tas yuav siv lwm yam kev ntsuas.
Metformin raug tshem tawm los ntawm lub raum, yog li ntawd, kev tshawb pom creatinine yuav tsum kuaj xyuas ua ntej pib ua ntej thiab thaum lub sijhawm noj cov tshuaj: nrog rau lub raum ua haujlwm - 1 zaug hauv ib xyoos, nrog txo KK thiab kev laus - 2-4 zaug / xyoo.
Cov tsos mob ntawm kev kis tus kab mob ntsws, ntsws thiab urogenital kheej kuj yuav tsum yog lub laj thawj ntawm kev mus ntsib tus kws endocrinologist.
Tawm tsam keeb kwm yav dhau los ntawm kev siv tshuaj metformin, dej cawv tshwj xeeb. Kev txwv tsis pub los ntawm lub luag haujlwm ntawm daim siab, ua cov glycogen endogenous, hem txoj kev loj hlob ntawm hypoglycemic thiab disulfiram-zoo li cov neeg mob.
Kev nqus tau cov vitamin B 12 tsis txaus ntseeg tau los ntawm kev thaiv nws txoj kev nqus. Qhov teeb meem tshwm sim nrog kev ncua lub sijhawm ntev ntawm cov tshuaj thiab thim rov qab. Yog tias pom cov tsos mob ntawm hypovitaminosis B12 raug soj ntsuam, metformin yuav tsum hloov nrog analogues.
Cawv rau lub peev xwm tswj hwm cov khoom siv nyuaj
Metformin Canon tsis cuam tshuam rau kev tswj hwm kev thauj khoom lossis cov txheej txheem nyuaj yog tias nws tau siv hauv kev kho mob monotherapy. Nrog cov kev kho mob nyuaj nrog sulfonylureas thiab cov tshuaj insulin, ib qho kev tiv thaiv hypoglycemic yog qhov ua tau, uas cuam tshuam loj dua psychomotor kev xav thiab kev saib xyuas.
Yam tsis tau xav txog
Metformin yog cov tshuaj uas muaj cov pov thawj ua tau zoo ntawm kev nyab xeeb thiab ua tau zoo, tus txheej txheem kub hauv kev kho mob ntshav qab zib, tab sis cov tshuaj pom tau tias cov neeg mob ntshav qab zib sib txawv. Feem ntau qhov tsis xav tau qhov tsis txaus ntseeg yog dyspeptic; thaum lub sijhawm hloov kho, qee leej tswj kom zam lawv. Yog tias koj noj tshuaj ntsiav nrog zaub mov noj, maj mam ntxiv cov tshuaj, koj tuaj yeem txo cov tsos mob ntawm tus mob plab.
Lwm qhov huab yog lactic acidosis, uas tshwm sim nrog kev txuam nrog metformin hauv lub cev txuam nrog raum tsis ua haujlwm. Cov xwm txheej zoo li no yog muaj tsawg heev, kwv yees ua ntej thiab xav kom thim tawm yeeb tshuaj. Nws yog qhov yooj yim rau kev soj ntsuam qhov degree ntawm qhov tshwm sim ntawm kev phiv los ntawm ntau yam plab hnyuv siab raum thiab kev siv tshuab hauv lub rooj.
Organs thiab tshuab | Hom ntawm phiv | Qhov tshwm sim |
CNS | hloov hauv saj (saj ntawm hlau) | feem ntau |
Kev kho mob txoj hnyuv | poob ntawm qab los noj mov, dyspeptic cuam tshuam | heev heev |
Hepatobiliary system | daim siab mob siab, kab mob siab | pheej xav |
Kev ua xua | erythema, tawv nqaij ua pob khaus thiab khaus, urticaria | tsis tshua muaj |
Kev paub kev zom zaub mov | lactic acidosis | tsis tshua muaj neeg pom |
Lwm yam kev xaiv | Hypovitaminosis B12, tsis tuaj yeem nqus tau ntawm folic acid, megaloblastic anemia | tsis tshua muaj neeg pom |
Tag nrho cov kev mob tshwm sim yog qhov thim rov qab thiab ploj tom qab tshem tawm ntawm Metformin Canon. Cov kev tshawb fawb soj ntsuam pom tias thaum muaj hnub nyoog 10-16 xyoo cov xwm txheej thiab cov zaus tshwm sim los ntawm cov kev mob tshwm sim zoo ib yam li cov neeg laus.
Cov txiaj ntsig ntawm kev sib txuam nrog lwm cov tshuaj
Nrog rau feem ntau cov kab mob hypoglycemic, Metformin ua ke zoo kawg nkaus, nws yog siv dav hauv kev kho mob nyuaj, tab sis, zoo li ib yam tshuaj, nws muaj nws cov kev txwv.
Contraindicated kev sib txuas ua ke
Xoo hluav taws xob xoo sib xyaw siv tshuaj raws li iodine, siv rau hauv kev tshawb nrhiav hluav taws xob, tuaj yeem ua rau mob lactic acidosis thaum noj tshuaj metformin. Yog li, 2 hnub ua ntej cov txheej txheem thiab 2 hnub tom qab kuaj xyuas, cov ntsiav tshuaj tau hloov nrog cov tshuaj insulin.
Tsis pom zoo kev sib txuas ua ke
Kev siv dej cawv thiab tshuaj pleev yeeb yaj kiab nrog kev siv tshuaj metformin kho tuaj yeem ua rau cov kab mob lactic acidosis. Qhov zoo sib xws yog ua tau nrog daim siab ua kom tsis zoo thiab kev noj zaub mov kom tsis muaj calorie ntau.
Yuav Siv Tau Ntau Yam
Thaum siv danazol nrog metformin, kev mob hypoglycemic yog ua tau. Yog tias tsim nyog, xws li kev sib koom ua ke yog qhov tsim nyog kom qhia meej cov koob tshuaj metformin.
Cov koob tshuaj tseem ceeb ntawm chlorpromazine thaiv qhov kev tso tawm ntawm cov tshuaj insulin endogenous, nce qib suab thaj. Antipsychotics kuj tseem xav kom tau ib feem kaum ntawm ib koob tshuaj metformin thaum lub sijhawm thiab tom qab kev kho mob loj.
Glucocorticosteroids txo qis cov ntshav qabzib, thaum nce nws qib hauv ntshav, ketosis muaj peev xwm tshwm sim hauv qhov xwm txheej huabCov. Nrog rau kev teem sij hawm ntawm cov kev ua dag zog li no, tus nqi ntawm metformin yog txo.
NSAIDs thiab ntxig cov diuretics nrog metformin ua rau lub raum ua teeb meem. Tus mob no yog qhov txaus ntshai rau kev loj hlob ntawm cov kab mob lactic acidosis.
Nifedipine ua kom zoo dua rau qhov nqus thiab qhov siab tshaj plaws ntawm metformin, qhov tseeb no yuav tsum raug coj los txiav txim siab thaum nqus ib qho kev kho mob.
Lawv txhim kho hypoglycemic muaj peev xwm ntawm cov tshuaj thiab cov tshuaj sib txuas nrog acarbose, insulin, sulfonylurea tshuaj.
Cov tshuaj uas siv los tswj ntshav siab tuaj yeem txhim kho cov nyhuv hypoglycemic thiab xav tau titration ntawm ib koob tshuaj metformin.
Cov Yuav Tsum Muaj
Ntxiv nrog rau kev ua kom tsis haum rau cov khoom xyaw ntawm cov mis, cov tshuaj tsis yog kws kho:
- Nrog rau mob caj dab tsis xeev, precoma, ketoacidosis;
- Tus mob ntshav qab zib nrog CC hauv qab 60 ml / min .;
- Muaj kev cuam tshuam los ntawm cov mob hnyav (lub cev qhuav dej, kub taub hau, mob hnyav);
- Nrog hypoxia tshwm sim los ntawm kev poob siab, sepsis, pathologies ntawm ob lub raum ntawm mob keeb kwm, mob ntsws, ntsws;
- Cov neeg mob uas muaj mob rau mob los yog mob ntev ua rau cov nqaij hauv hypoxia;
- Rau lub sijhawm ntawm kev phais mob, nyob rau hauv kev kho mob ntawm kev raug mob hnyav thiab kub hnyiab;
- Cov neeg quav cawv mus ntev, cov neeg uas haus cawv heev;
- Nrog tus mob hepatic kawg;
- Hauv lub xeev lactic acidosis;
- Cov menyuam yaus hnub nyoog qis dua 10 xyoo, cev xeeb tub thiab lactating niam;
- Ib ntus: kev txwv nyob rau lub sijhawm ntawm kev ua haujlwm thiab kev tshawb nrhiav hluav taws xob.
Hom ntawm overdose
Hauv cov kev tshawb fawb soj ntsuam hauv cov neeg ua haujlwm pab dawb uas tau noj tshuaj kaum zaus ntawm metformin (85 g), cov ntshav qog ntshav qab zib tsis txhim kho, lawv pom cov cim ntawm cov kab mob lactic acidosis.
Koj tuaj yeem paub tus mob los ntawm kev tsis haum siab, kev hloov ntawm lub cev ntawm kev tso quav, qhov kub qis dua qhov ib txwm, mob plab thiab mob hauv lub epigastrium, ua tsis taus pa, ua tsis tau haujlwm thiab tsis nco qab, tsaus muag thiab tsis nco qab. Qhov xwm txheej yuav tsum tau maj maj kho cov tshuaj thiab tsev kho mob. Cov lactate thiab metformin cov khoom seem hauv tsev kho mob yog kho los ntawm hemodialysis.
Kev Ntsuas Cov Tshuaj Ntshav Qab Zib
Txog Metformin Canon, kev tshuaj xyuas feem ntau yog qhov zoo. Ntau tus sau tseg tias muaj cov tshuaj ntawm cov nqi peev nyiaj. Ib nrab ntawm cov neeg mob qhia tias tswj cov piam thaj kom ruaj khov, ua rau lub cev poob, thiab tswj tsis tau qab los.
Ntawm qhov kev ntsuas tsis zoo, kev tsis txaus siab ntawm cov kev mob tshwm sim hauv daim ntawv ntawm lub plab zom mov, uas tsis ploj nrog lub sijhawm, yeej.Pom tseeb, hauv cov xwm txheej zoo li no, nws tsim nyog sab laj nrog koj tus kws kho mob, vim tias txawm tias cov tshuaj metformin-based analogues muaj ntau yam kev pabcuam uas tuaj yeem ua rau ua xua thiab lwm yam tshuaj tiv thaiv. Nws yog qhov muaj peev xwm los hloov cov generic nrog thawj glucophage.
Analogues ntawm cov tshuaj
Rau Metformin Canon, ntau hom tshuaj yeeb yaj kiab tuaj yeem yog analogues. Pharmacological sib npaug nrog kev kho mob zoo ib yam thiab cov khoom siv yooj yim ntawm metformin yog:
- Glucophage - ib hom tshuaj Fabkis qub tsim nyog txog 130 rubles .;
- Metfogamma - Cov ntsiav tshuaj German ntawm tus nqi nce txog 330 rubles .;
- Formmetin yog txoj kev pabcuam hauv tsev, lawv muag rau 250 rubles .;
- Sofamet yog lus Bulgarian, tuaj yeem yuav rau 109 rubles.
Raws li kev paub txog ATX kev faib tawm, daim ntawv tuaj yeem ua tau ntxiv los ntawm Siofor, Bagomet, Avandamet, Metformin Teva thiab lwm yam duab. Cov chaw tsim khoom ntawm Metformin Canon kuj muaj ib qho ua ke nrog lub zog ntev. Cov tshuaj maj mam tso tawm muaj nyob hauv qhov ntau npaum li 500, 750 thiab 1000 mg. Cov ntawv sau ua ntej "ntev" thiab lwm yam analogues
Kev lag luam kws kho mob niaj hnub no puv nrog cov tshuaj tiv thaiv kab mob, tab sis tawm ntawm 10 chav kawm ntawm cov tshuaj tsim los tswj hom 2 ntshav qab zib, metformin ib leeg tseem tsis muaj qhov kev tiv thaiv. Qhov no tsuas yog tus nqi pheej yig, kawm tau zoo uas yog tus mob ntshav qab zib xav tau thaum twg los tau.
Cov lus qhia tseeb txog metformin tuaj yeem nrhiav pom hauv video.