Cov cuab yeej pab ua kom ntshav khov. Tsuas siv tau rau cov neeg laus neeg mob. Cov tshuaj sib xyaw ua ke ntawm lisinopril ua kom cov hlab ntshav khov, kho kom ntshav siab thiab tiv thaiv cov leeg plawv. Cov tshuaj muaj peev xwm ntxuav lub cev ntawm cov dej qab ntsev ntau dua.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lisinopril
Cov cuab yeej pab ua kom ntshav khov.
ATX
S09AA03
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj no tau tso tawm rau hauv cov ntsiav tshuaj. Ntim lawv rau 20, 30 tej daim. Lisinopril (lisinopril) yog ib qho kev txiav txim siab uas txiav txim siab cuam tshuam ntawm ib yam tshuaj.
Pharmacological kev txiav txim
Cov tshuaj nquag ua haujlwm yog ACE inhibitor (lub hauv paus tseem ceeb hauv kev tswj hwm ntawm cov ntshav siab). Lisinopril inhibits qhov hloov pauv ntawm cov roj ntsha biiotensin i oligopeptide rau angiotensin ii octapeptide. Muaj qhov txo qis ntawm cov hlab ntsha ntsig txog ntshav nce siab, qhov txo qis hauv lub plawv tawm, thiab nce ntxiv hauv cov zis. Yog li, qhov cuab yeej txo cov ntshav siab thiaj li qis.
Cov Tshuaj Pharmacokinetics
30% nqus los ntawm cov hnyuv. Koj tuaj yeem noj tsis hais cov tshuaj twg. Qhov siab kawg ntawm cov khoom tseem ceeb hauv cov ntshav ntshav tau mus txog tom qab 6-7 teev. Lub sijhawm nce mus rau 8-10 teev nyob rau hauv cov ntaub ntawv ntawm lub sijhawm tom qab lub sijhawm dhau los. Yuav luag tsis khi rau cov ntshav protein. Ib nrab-lub neej ntawm cov tshuaj nyob rau hauv daim ntawv hloov pauv nrog zis yog 12 teev.
Cov tshuaj yog 30% nqus los ntawm cov hnyuv.
Kev ntsuas rau siv
Tus neeg mob xav tau kev kho mob yog tias cov kab hauv qab no ntawm cov hlab plawv tshwm sim:
- tsis hnov lus patency ntawm ib lossis ntau lub raum cov hlab ntsha;
- tus neeg mob txom nyem myocardial infarction, tab sis hemodynamic tsis yog ib txwm;
- lub caij nyoog ntev ntxiv ntawm cov ntshav siab tau sau tseg;
- ob lub raum cuam tshuam rau cov neeg mob insulin;
- lub plawv tsis ua hauj lwm.
Nrog rau cov kev ua txhaum no nyob rau hauv lub cev, tus kws kho mob txiav txim siab kho lub sijhawm thiab xav tau tshuaj ntxiv.
Cov Yuav Tsum Muaj
Nws yog txwv tsis pub haus ntsiav tshuaj hauv cov xwm txheej hauv qab no:
- nqaim cov lumen ntawm cov hlab ntshav uas pub lub raum (lub raum leeg ntshav hlab ntsha);
- ob lub raum lim ntshav los ntawm creatinine hauv tsawg dua 30 ml / min;
- pom mob raum tsis zoo;
- muaj kev fab tshuaj rau cov tshuaj lossis tshuaj uas sim ACE kev ua si;
- kev mob rau angioedema;
- hemodialysis;
- hypertrophic cardiomyopathy, mitral lossis aortic stenosis nrog cov mob ncig;
- lub cev tsis muaj peev xwm los tsim lactase;
- lub sijhawm lactation lossis cev xeeb tub;
- hemodynamic tsis muaj peev xwm tsis ruaj khov tom qab mob myocardial infarction;
- ua txhaum ntawm kev hloov pauv ntawm galactose rau piam thaj;
- piam thaj-galactose malabsorption syndrome.
Cov tshuaj no yog contraindicated nyob rau hauv mob raum tsis ua haujlwm.
Qhov tshwm sim ntawm lisinopril nyob rau hauv menyuam yaus tseem tsis tau to taub tag nrho, yog li ntawd, cov ntsiav tshuaj tsis tau noj mus txog thaum muaj hnub nyoog 18 xyoo.
Yuav noj li cas
Kev noj tshuaj yog nqa tawm thaum sawv ntxov. Ib qho ntxiv, koj yuav tsum haus dej kom ntau. Tus kws kho mob yuav tuaj yeem tsim qhov tseeb kev noj tshuaj tom qab kuaj mob. Cov lus qhia taw qhia cov ntaub ntawv hauv qab no nyob ntawm tus kabmob:
- Arterial kub siab. Ua ntej, haus 5 mg ib hnub twg. Tom qab 20-30 hnub, koj tuaj yeem nce ntxiv qhov tshuaj rau txhua hnub rau 10-20 mg. Nws raug tso cai siv ntau tshaj 40 mg ntawm ib zaug.
- Cov Hypovolemia, lub cev tsis muaj ntsev-metabolism hauv lub cev, cov neeg laus laus. Qhov tsim nyog ntawm lisinopril yog 2.5 mg rau ib hnub.
- Mob myocardial infarction nrog cov leeg ntshav ruaj khov. 5 mg yuav qaug thaum nruab hnub thiab 5 mg dua hauv ib hnub. Hauv peb hnub, kev muab ntau ntxiv rau 10 mg. Nrog lub siab systolic siab nyob rau hauv thawj 2-3 hnub muab tus neeg mob 2.5 mg.
- Arterial hypotension. Txhawm rau kom ruaj khov lub xeev, noj li 2.5 -5 mg ib hnub. Yog tias qhov ntau npaum li cas ntawm cov tshuaj ntshav, thiab cov ntshav siab mus txuas ntxiv, tsum tsis txhob noj cov tshuaj lisinopril.
- Lub plawv tsis ua hauj lwm. Nws yog ib qho tsim nyog kom haus 2.5 mg ib hnub twg. Tom qab ib hlis, koj tuaj yeem nce ntxiv qhov koob tshuaj rau 5 mg.
Hauv kev mob plawv sai, koj yuav tsum haus 2,5 mg ib hnub twg.
Txhua lub ntsiav tshuaj muaj faib kev sib cais kom pab tswj hwm txoj haujlwm. Yog tias tsim nyog, koj tuaj yeem yooj yim faib cov ntsiav tshuaj mus rau ntau qhov chaw. Lub sijhawm tiv thaiv kev kho mob yuav tsum tsis pub tshaj 6 lub lis piam.
Nrog ntshav qab zib
Yog tias tawm tsam keeb kwm ntawm ntshav qab zib, albuminuria tshwm sim lossis ntshav nce siab, noj 2.5 mg. Qhov ntau npaum tau yog tsim rau ib qho tshuaj noj rau thaum sawv ntxov. Nrog rau kev txo qis hauv lub raum kev ua haujlwm, kev saib xyuas txij nkawm yuav yog 5-10 mg ib hnub. Nyob ntawm theem ntawm cov ntshav siab. Qhov siab tshaj plaws 20 mg tuaj yeem noj tau.
Sab sij huam
Cov tshuaj yuav ua rau muaj kev phiv uas tshwm sim los ntawm ntau yam plab hnyuv siab raum thiab tshuab. Muaj qee zaus, qhov kev ua haujlwm ntawm hepatic transaminases nce, cov concentration ntawm creatinine thiab urea hauv cov ntshav cov ntshav nce ntxiv.
Kev kho mob txoj hnyuv
Feem ntau cov neeg mob tau ntxhov siab los ntawm kev tso quav tsis zoo, xeev siab. Qhov mob yuav tshwm sim hauv plab, xeev siab. Kev siv sijhawm ntev tuaj yeem ua rau mob hlab ntshaws, tawv nqaij tsis ua haujlwm, nce bilirubin hauv cov ntshav.
Thaum noj tshuaj, xeev siab yuav tshwm sim.
Hematopoietic plab hnyuv siab raum
Hauv qab dej cawv ntawm lisinopril, ntshav siab poob qis. Qee qhov xwm txheej, lub siab lub plawv muaj zog, mob tachycardia tshwm sim, thiab cov hlab ntsha thiab cov hlab ntsha ntawm cov leeg sab saud cuam tshuam (Raynaud's syndrome). Cov tshuaj tiv thaiv nquag tuaj yeem ua rau ua txhaum cai ntawm cov ntshav mus rau lub plawv nqaij thiab cerebrovascular, yog tias txais tos tsis zoo.
Nruab nrab hauv lub paj hlwb
Feem ntau tom qab noj kiv taub hau, mob taub hau tshwm tuaj, nkees nkees zuj zus tuaj, thiab cov ntsiab lus ntawm cov xim poob qis dua. Kev xav ntawm lub siab ntsws, teeb tsa ntawm lub cev, pw tsaug zog, lossis pw tsis tsaug zog yog qhov tsawg.
Kev ntxhov siab, tsaus muag thiab tsis meej pem tshwm sim tom qab siv ntev thiab tswj tsis tau.
Los ntawm lub tshuab ua pa
Tom qab kev tswj hwm, cov tsos mob uas zoo ib yam li tau khaub thuas tuaj yeem tshwm sim: hnoos qhuav, mob caj pas thiab lub cev qhuav, mob ntswg thiab cov hlab ntsha txhaws. Tsis tshua muaj, mob ntsws muaj tshwm sim.
Tom qab noj nws, koj yuav pom cov tsos mob uas zoo li tau khaub thuas: hnoos qhuav, mob caj pas thiab mob qa.
Ntawm ib sab ntawm daim tawv nqaij
Kev ua xua tuaj yeem tshwm sim nyob rau hauv daim ntawv ntawm o ntawm lub ntsej muag thiab lwm qhov ntawm lub cev, urticaria. Qee tus neeg mob pib mob Stevens-Jones syndrome, lub cev lub cev hloov mus rau ultraviolet rays nce, cov leeg mob tau hnov.
Los ntawm genitourinary system
Cov haujlwm raum feem ntau yog qaug zog los ntawm lisinopril. Muaj qee zaus, muaj uremia, proteinuria, tsis muaj zis.
Cov lus qhia tshwj xeeb
Thaum kho, nws yog qhov tsim nyog los tswj theem ntawm cov ntshav siab. Ua ntej noj, diuretics raug tso tseg kom txo qhov kev pheej hmoo ntawm kev txo qis siab. Kev kho nrog lisinopril yuav tsum tsis txhob pib yog tias, nrog mob myocardial infarction, qhov tsis zoo yog pom. Muaj kev cuam tshuam kev kho mob rau lub plawv tsis ua haujlwm, vim tias cov tsos mob yuav rov tshwm sim tom qab ib ntus.
Siv rau lub sijhawm qub
Hauv cov laus, cov nyhuv ntawm lisinopril yuav muaj ntau dua. Txoj kev kho yuav tsum tau ua nrog ceev faj.
Hauv cov laus, cov nyhuv ntawm lisinopril yuav muaj ntau dua.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Vim tias cov rog nkees nce ntxiv, qhov zoo li kiv taub hau thiab mob taub hau hauv qee cov neeg mob, nws yog qhov yuav tsum tau ua tib zoo tswj lub tsheb.
Siv thaum cev xeeb tub thiab lactation
Thaum cev xeeb tub, kev siv cov tshuaj tsis raug txwv. Lisinopril tuaj yeem ua rau me nyuam hauv plab tsis zoo, uas tej zaum yuav cuam tshuam nrog lub neej. Tsis muaj pov thawj dab tsi ntawm kev nkag mus rau hauv niam mis, tab sis nws raug nquahu kom tsis txhob pub niam mis thaum noj cov tshuaj.
Xaj Lisinopril Stad rau me nyuam
Txog thaum muaj hnub nyoog 18 xyoo, tsis tau txais cov tshuaj tsis raug cai, vim tias kev nyab xeeb thiab ua haujlwm tau zoo hauv menyuam yaus tsis to taub tag nrho.
Txog thaum muaj hnub nyoog 18 xyoo, tsis tau txais cov tshuaj tsis raug cai, vim tias kev nyab xeeb thiab ua haujlwm tau zoo hauv menyuam yaus tsis to taub tag nrho.
Noj ntau dhau
Kev tswj tsis tau cov ntsiav tshuaj ua rau lub ntsej muag ntawm txoj hlab ntshav khiav ceev, poob siab, bradycardia, thiab lub raum tsis ua haujlwm. Tus neeg mob yog cuam tshuam los ntawm electrolyte tshuav nyiaj li cas.
Kev cuam tshuam nrog lwm yam tshuaj
Tib lub sijhawm tswj hwm nrog qee cov tshuaj ua rau cov teebmeem hauv qab no:
- diuretics thiab lwm yam tshuaj uas ua rau txo qis ntshav siab tuaj yeem txhim kho cov nyhuv ntawm cov tshuaj;
- potassium-sparing diuretics tuaj yeem ua rau hyperkalemia;
- nyob hauv qab ntawm cov tshuaj pleev xim thiab cov tshuaj tsis-steroidal los tiv thaiv cov tshuaj lom, cov nyhuv hypotensive tsis tau tiav tam sim ntawd;
- yog tias kev kho cov kua qaub lithium, nws yog ib qho tsim nyog los soj ntsuam kev saib xyuas ntawm ib qho tshuaj lom hauv cov ntshav;
- cov nyhuv pharmacological ntawm lisinopril yog txhim kho thaum noj nrog tshuaj ntsiav tsaug zog thiab tshuaj loog;
- cov neeg sawv cev uas ua rau kom tso tawm ntawm norepinephrine tuaj yeem ua kom tsis muaj zog ntawm cov lisinopril;
- kev tswj hwm ib txhij nrog Allopuronol, Procainamide, cytostatics, immunosuppressants, cov kab ke glucocorticoids ua rau txo qis ntshav dawb hauv cov ntshav;
- cov nyhuv ntawm kev noj tshuaj tiv thaiv kab mob tsis muaj zog;
- sodium chloride muaj peev xwm txo cov nyhuv ntawm cov tshuaj antihypertensive.
Cawv tau zoo
Kev haus dej cawv txhim kho cov nyhuv ntawm cov tshuaj, yog li kev haus dej haus cawv tsis pom zoo.
Kev haus dej cawv txhim kho cov nyhuv ntawm cov tshuaj, yog li kev haus dej haus cawv tsis pom zoo.
Nrog saib xyuas
Kev ceev faj yuav tsum tau tawm dag zog rau lub hauv siab uas tshwm sim los ntawm cov ntshav tsis txaus rau cov leeg plawv. Nws yog ib qho tsim nyog yuav tsum sab laj tus kws kho mob nrog kev puas tsuaj rau cov hlab ntsha ntawm lub hlwb, kom tsis txhob ua rau mob stroke. Yog tias tsis muaj teeb meem lub raum, kev siv ntau npaum li cas.
Analogs
Cov tshuaj muaj analogues uas tuaj yeem hloov cov cuab yeej no. Cov no suav nrog:
- Lisinopril. Nws tus nqi tsis ntau tshaj 80 rubles rau 30 ntsiav tshuaj. Qhov ntau npaum li cas ntawm cov tshuaj txuam hauv cov lus sib xyaw ntawm cov ntsiav tshuaj kuj txawv.
- Lisinotone. Muaj nyob hauv 28 daim ib pob. Tus nqi yog 120-200 rubles. Muaj cov tshuaj sodium. Nrog kev ntuav thiab raws plab yuav tsum siv nrog ceev faj. Hauv cov laus nws yog txwv tsis pub noj.
- Lysigamma. Tus nqi rau 30 daim yog 130 rubles. Raws li yog ib feem ntawm lisinopril thiab pabcuam ntu. Nws raug nquahu kom xyuam xim nrog qee qhov xwm txheej lossis kab mob.
- Diroton. Lawv tsim khoom 14, 56 daim ib pob. Tus nqi ntawm cov tshuaj txawv ntawm 200 txog 700 rubles. Zoo ib yam li Lisinopril Stad. Nws yog ntxiv rau siv los tswj cov ntshav tsis ruaj khov hemodynamic hauv myocardial infarction.
Ua ntej hloov cov tshuaj nrog tshuaj analogue, sab laj rau cov kws kho mob tshwj xeeb. Cov lus qhia tau qhia tias muaj kev cuam tshuam tshwm sim thiab contraindications.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Koj yuav tsum muab daim ntawv yuav tshuaj ntawm lub tsev muag tshuaj thiaj yuav cov tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Sij hawm yauv mus yuav tom tsev muag tshuaj yog tau.
Nqe rau Lisinopril Stada
Tus nqi ntawm cov ntsiav tshuaj hauv Russia yog los ntawm 100 txog 170 rubles.
Cia rau cov neeg mob rau cov tshuaj
Khaws lub pob tshuaj rau hauv qhov chaw tsaus thaum kub txog + 25 ° C.
Khaws lub pob tshuaj rau hauv qhov chaw tsaus thaum kub txog + 25 ° C.
Hnub tas sij hawm
Koj tuaj yeem khaws 3 xyoos.
Chaw tsim tshuaj paus
MAKIZ-PHARMA LLC lossis Hemofarm LLC, Russia.
Kev txheeb xyuas txog Lisinopril Stad
Cov tshuaj tsis pheej yig, tab sis muaj ntau tus lej thiab kev tsis haum ntawm qhov tsis haum. Coob tus tsis lees txais vim tias cov tshuaj tsis pib sai.
Thaum cev xeeb tub, kev siv cov tshuaj tsis raug txwv.
Cov kws kho mob
Egor Konstantinovich, kws kho plawv
Kuv sau tshuaj Lisinopril Stad nrog rau lwm yam tshuaj kom tau txais cov nyhuv zoo. Ib qho ntxiv, tus neeg mob yuav tsum tsim kev noj zaub mov kom zoo. Hauv kev kho txoj kev nyuaj, cov tshuaj ua rau kev so ntawm lub plawv ntsa thiab ib qho kev txo cov ntshav siab.
Julia Makarova, kws kho mob hlwb
Nrog lub caij nyoog ntev ntxiv hauv siab, cov tshuaj yeej pab. Cov tshuaj daws pib ua nyob rau hauv 40-60 feeb. Nws raug nquahu kom noj tsawg kawg ib hlis, ua raws cov lus qhia ntawm tus kws khomob tuaj koom. Hauv kev ua haujlwm ntawm kev kho mob, nws yog ib qhov tsim nyog los saib xyuas qhov mob ntawm ob lub raum. Nws yuav tsum nco ntsoov tias tsis tas yuav ua ke ua ke noj tshuaj nrog hemodialysis los ntawm kev ua haujlwm siab.
Cov neeg mob
Sergey Viktorovich, hnub nyoog 45 xyoos
Nws tau txais kev kho mob nrog cov tshuaj no thiab tom qab 10 hnub nws zoo dua. Kev nce siab, tab sis tsis tshua muaj. Mob taub hau ce tsis thab. Thawj thawj hnub tom qab noj, lub qog ua kua rau hauv lub qhov ncauj tau qhuav thiab mloog tau nkees. Cov kev mob tshwm sim tsis zoo tom qab ib lub lim tiam. Txaus siab nrog qhov tshwm sim ntawm kev noj tshuaj.
Egor, hnub nyoog muaj 29 xyoos
Tom qab siv sijhawm ntev, hnoos thiab mob qa tshwm sim. Tus kws kho mob uas tuaj koom tau tso tseg qhov no thiab qhia hais kom noj lwm yam tshuaj. Ceev faj yuav tsum tau siv thaum lub sijhawm siv ntev.
Anastasia Romanovna, 32 xyoo
Cov tshuaj pab ua kom cov ntshav siab nyob rau hauv thawj tawg. Ib qho tshuaj zoo uas kuv yawg coj tom qab mob stroke. Cov chaw tsim khoom zoo thiab tus nqi tsim nyog.
