Lysoril, lossis lisinopril dihydrate, yog ib hom tshuaj uas siv los txo cov ntshav siab thaum nws nce (siab).
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Lisinopril.
Lysoril, lossis lisinopril dihydrate, yog ib yam tshuaj uas siv los txo cov ntshav siab thaum nws nce.
ATX
Cov tshuaj muaj qhov cim npe C09AA03 Lisinopril.
Tso cov ntawv thiab cov nyob ua ke
Muaj cov ntaub ntawv xws li ntsiav tshuaj nrog qhov siab ntawm 2.5; 5; 10 lossis 20 mg txhua.
Raws li ib feem ntawm cov tshuaj, cov tshuaj tseem ceeb yog lisinopril dihydrate. Cov khoom siv ntxiv yog mannitol, calcium hydrogen phosphate dihydrate, magnesium stearate, pob kws hmoov nplej, E172, lossis oxide hlau liab.
Cov ntsiav tshuaj hloov puag ncig, biconvex, liab dawb hauv xim.
Pharmacological kev txiav txim
Hais txog cov tshuaj uas cuam tshuam rau lub xeev ntawm cov hlab plawv system. Cov tshuaj tiv thaiv kev hloov pauv ntawm angiotensin 1 rau angiotensin 2, muaj cov vasoconstrictor effect thiab inhibits qhov tsim ntawm adrenal aldosterone. Txo peripheral vascular tsis kam, ntshav siab, ntshav siab nyob rau hauv capillaries ntawm lub ntsws, preload. Nws kho txhim kho cov teebmeem hauv plawv thiab nce myocardial kam rau ua rau cov neeg muaj lub plawv tsis ua haujlwm.
Txo cov ntshav siab tshwm sim ib teev tom qab siv tshuaj.
Nrog lub sijhawm siv Lizoril, qhov txo qis ntawm myocardial hypertrophy thiab leeg ntsa ntawm cov tawv tiv thaiv yog pom. Txo cov ntshav siab tshwm sim ib teev tom qab siv tshuaj. Qhov txiaj ntsig zoo tshaj plaws tau tiav tom qab 6 teev, lub sijhawm ntawm cov nyhuv yog ib hnub. Nws nyob ntawm qhov koob tshuaj, lub xeev ntawm lub cev, kev ua haujlwm ntawm lub raum thiab mob siab.
Cov Tshuaj Pharmacokinetics
Qhov siab tshaj plaws tau pom nyob hauv 7 teev tom qab kev tswj hwm. Qhov nyiaj nruab nrab uas tau nqus rau hauv lub cev yog 25%, qhov tsawg kawg nkaus yog 6%, thiab qhov ntau yog 60%. Hauv cov neeg mob uas lub plawv tsis ua hauj lwm, bioavailability txo qis los ntawm 15-20%.
Ua rau hauv zis tsis hloov pauv. Kev noj tsis cuam tshuam rau kev nqus. Cov theem ntawm kev nkag mus los ntawm kev tso ntshav thiab ntshav-hlwb teeb meem yog tsawg.
Kev ntsuas rau siv
Cov tshuaj yog kws kho nyob rau hauv cov xwm txheej zoo li no:
- kev kho lub sij hawm luv luv ntawm tus mob myocardial infarction (txog 6 lub lis piam);
- arterial kub siab;
- ntshav qab zib nephropathy (txo cov protein ntau hauv cov zis rau cov neeg mob ntshav qab zib uas muaj ntshav nce siab thiab nce ntshav siab).
Cov Yuav Tsum Muaj
Nws yog qhov txwv tsis pub coj yog tias pom:
- Hypersensitivity rau ib qho twg ntawm cov yeeb tshuaj lossis tshuaj los ntawm tib pawg pharmacological.
- Edema nyob hauv keeb kwm ntawm hom angioneurotic.
- Tsis hem tsis hemodynamics tom qab mob myocardial infarction.
- Lub xub ntiag ntawm theem siab ntawm creatinine (ntau dua 220 μmol / l).
Cov tshuaj yog contraindicated rau cov neeg mob tab tom mob hemodialysis, thiab rau cov poj niam thaum cev xeeb tub thiab lactation.
Nrog saib xyuas
Cov tshuaj tau sau tawm kom zoo nyob rau hauv lub xub ntiag ntawm arterial stenosis lossis valves - mitral thiab aortic, lub raum thiab daim siab tsis ua haujlwm, mob plawv nres, nce potassium ntau ntau, tom qab tsis ntev los no tau ua haujlwm thiab raug mob, nrog ntshav qab zib mellitus, kab mob ntshav, kev tsis haum tshuaj.
Yuav ua li cas noj Lizoril?
Sab hauv 1 lub sijhawm hauv ib hnub. Qhov ntau ntawm cov tshuaj tau xaiv hauv txhua kis ntawm tus kheej. Feem ntau, kev kho mob pib nrog 10 mg. Tom qab ntawv kho yog tsim nyog.
Nrog ntshav qab zib
Hauv cov neeg mob uas muaj ntshav qab zib hom 2, qhov tshuaj thawj zaug yog 10 mg 1 zaug nyob rau ib hnub.
Phiv los ntawm Lizoril
Ib qho tshuaj noj tuaj yeem ua rau muaj kev mob tshwm sim, qee qhov nws ploj mus nws tus kheej, qee qhov yuav tsum tau kho.
Kev kho mob txoj hnyuv
Lub qhov ncauj qhuav thiab xeev siab, ntuav, mob plab, raws plab, cem quav, mob ntawm tus txiav, tsis qab los noj mov, daim siab tsis ua hauj lwm, daj ntseg, cholestasis, angioedema ntawm txoj hnyuv, hepatocellular yam kab mob siab.
Hematopoietic plab hnyuv siab raum
Kev txo qis ntawm hematocrit thiab hemoglobin, kev ua kom tsis txhob muaj cov kabmob pob txha liab, kev hloov pauv hauv cov ntshav txaus, cov hlab ntsha, cov ntshav tsis muaj zog, mob ntshav siab, neutropenia, leukopenia, kab mob autoimmune, lymphadenopathy, hemolytic type anemia.
Nruab nrab hauv lub paj hlwb
Tsis nco qab, tsaus muag, mob pob txha, hnov qhov tsis hnov tsw, tsis pom kev, hnov qhov muag, hnov qhov muag thiab hnov qab, teeb meem pw tsaug zog, hloov lub siab, mob taub hau thiab kiv taub hau, teeb meem nrog kev ua kom sib haum.
Los ntawm lub tshuab ua pa
Cov mob voos sab saud, hnoos, rhinitis, mob ntsws thiab hnoos qeev, ua tsis taus pa, ua pa ntawm qhov txhaws hlab ntsha, ua xua, ua xua.
Los ntawm cov hlab plawv system
Orthostatic tshwm sim (arterial hypotension), mob stroke, myocardial infarction, Raynaud's syndrome, palpitations, cardiogenic poob siab, lub plawv thaiv 1-3 degrees, nce siab hauv cov hlab ntsws capillaries.
Kev ua xua
Muaj kev cuam tshuam tshwm sim los ntawm daim tawv nqaij thiab txheej subcutaneous xws li ua pob khaus, khaus khaus, muaj qhov mob rhiab - angioedema, o ntawm cov nqaij ntawm lub ntsej muag thiab caj dab, hyperemia, urticaria, eosinophilia.
Muaj peev xwm tshwm sim los ntawm daim tawv nqaij thiab txheej subcutaneous, xws li pob khaus, khaus.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Vim hais tias thaum noj Lizoril, nws yuav muaj kiv taub hau, ploj mus ntawm qhov kev qhia tawm, tom qab ntawd thaum ua haujlwm nrog cov txheej txheem nyuaj thiab tsav tsheb, kev ceev faj yuav tsum siv lossis lossis, yog tias ua tau, kom tso tseg txoj haujlwm no.
Cov lus qhia tshwj xeeb
Qhov ntau npaum ntawm cov tshuaj yuav txawv, nyob ntawm lub hnub nyoog, qhov haujlwm ua haujlwm ntawm lub cev (lub siab, mob siab, ob lub raum, cov hlab ntsha).
Nrog rau kev mob plawv, mob ntshav qab zib cerebrovascular pathology, lub plawv tsis ua haujlwm, mob plawv, mob hlab ntsha tawg, hlab ntsha tuaj yeem loj hlob tuaj. Yog li, kev hloov tshuaj thiab kev saib xyuas tas li ntawm cov neeg mob yog qhov yuav tsum tau ua.
Siv rau lub sijhawm qub
Yuav tsum txhaj koob kho kom haum.
Txiag tej menyuam
Cov tshuaj yog contraindicated rau hauv cov menyuam yaus, vim tias tsis muaj cov kev tshawb fawb soj ntsuam tau tshwm sim.
Siv thaum cev xeeb tub thiab lactation
Tsis taw.
Daim ntawv thov rau lub raum khiav tsis zoo
Thaum sau tshuaj rau cov neeg mob uas lub raum tsis ua haujlwm, qhov tshuaj ntau npaum li cas tau txiav txim siab los ntawm theem ntawm creatinine hauv cov ntshav thiab lub cev teb rau kev kho.
Thaum sau tshuaj rau cov neeg mob uas lub raum tsis ua haujlwm, qhov tshuaj ntau npaum li cas tau txiav txim siab los ntawm theem ntawm creatinine hauv cov ntshav thiab lub cev teb rau kev kho.
Nrog kev noj qab haus huv ob lub raum leeg mob stenosis, cov tshuaj tuaj yeem ua rau muaj ntshav ntau npaum li cas urea thiab tus neeg tsim muaj cov ntshav siab, lub raum ntshav siab, lossis mob ntshav siab ntau thiab ua rau lub raum tsis ua haujlwm. Nrog rau qhov kev pleev ib ce, nws yog qhov tsim nyog ua tib zoo sau tshuaj diuretics thiab saib xyuas qhov tsuas tshuaj, tswj qib ntawm poov tshuaj, creatinine thiab urea.
Nrog kev txhim kho ntawm myocardial infarction hauv cov neeg mob uas lub raum tsis ua haujlwm, Lizoril yog contraindicated.
Siv rau lub siab ua haujlwm tsis zoo
Kev siv tshuaj noj ib qho tsis tshua muaj peev xwm ua rau muaj kev cuam tshuam ntawm cov mob hepatobiliary. Txawm li cas los xij, qee zaum nrog kev txiav txim siab rau daim siab, mob daj ntseg, ua kom mob hyperbilirubinemia / hyperbilibinemia, thiab kev nce siab hauv cov kab mob hepatic transaminase yuav tshwm sim. Hauv qhov no, cov tshuaj raug muab tso tseg.
Noj ntau dhau ntawm lizoril
Cov tsos mob muaj qhia nyob rau hauv daim ntawv ntawm txo qis ntshav siab, tsis txaus ntseeg ntawm electrolytes, lub raum tsis ua haujlwm, mob tachy lossis bradycardia, kiv taub hau, hnoos, ntxhov siab. Kev kho mob raws qab.
Kiv taub hau yog ib qho ntawm cov tsos mob ntawm overdose.
Nws yuav tsim nyog los yaug lub plab, ntxias cov ntuav, muab sorbents lossis lim ntshav. Nyob rau hauv cov mob hnyav, kev kho Txoj kev lis ntshav yog kho mob, catecholamines raug tswj hwm leeg.
Kev cuam tshuam nrog lwm yam tshuaj
Diuretics: muaj qhov nce ntawm cov nyhuv ntawm cov ntshav siab.
Lithium: Kev siv yooj yim tsis pom zoo. Toxicity nce. Yog tias tsim nyog, tswj qib theem ntawm lithium hauv cov ntshav.
NSAIDs: cov nyhuv ntawm ACE inhibitors poob qis, muaj cov poov tshuaj ntau ntxiv hauv cov ntshav, uas ua rau muaj kev pheej hmoo ntawm lub raum.
Tshuaj rau ntshav qab zib: qhov txo qis hauv cov ntshav qabzib, qhov kev pheej hmoo ntawm cov ntshav qog ntshav qab zib thiab coma nce.
Estrogens: khaws cov dej hauv lub cev, yog li lawv tuaj yeem txo cov nyhuv tshuaj.
Lwm yam tshuaj rau txo ntshav siab thiab tshuaj tiv thaiv kev ntxhov siab: qhov phom sij ntawm qhov txo qis hauv cov ntshav siab.
Cawv tau zoo
Puas muaj lawm. Tej zaum qhov nce ntawm cov nyhuv hypotensive ntawm lisinopril, txoj hlab ntaws hypotension yuav dhau los.
Analogs
Cov lus txhais ntawm Lysoril yog Lisinoton, Lisinopril-Teva, Irumed, Lisinopril, Diroton.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kev tshaj tawm tshuaj kho mob yog qhov yuav tsum tau ua.
Kuv puas yuav tau yam tsis muaj daim ntawv yuav tshuaj?
Tsis yog.
Nqi
Tus nqi ntawm 1 pob yog txawv nyob ntawm seb muaj pes tsawg leej ntsiav tshuaj thiab ntau npaum li cas. Yog li, tus nqi rau 28 ntsiav tshuaj ntawm 5 mg ntawm cov tshuaj yog 106 rubles.
Cia rau cov neeg mob rau cov tshuaj
Nws raug nquahu kom khaws cov khoom hauv ib qho chaw deb ntawm cov menyuam. Cov txheej txheem kub yuav tsum tsis pub tshaj 25 ° C.
Hnub tas sij hawm
Tsis ntev tshaj 3 xyoos.
Chaw tsim tshuaj paus
Lub tuam txhab Indian Ipka Limited Lub chaw soj nstuam.
Cov tshuaj yog contraindicated rau hauv cov menyuam yaus, vim tias tsis muaj kev tshawb fawb hauv lub tsev kho mob twg tau ua.
Xyuas
Oksana, hnub nyoog 53 xyoos, Minsk: “Lizoril tau raug sau tseg 3 xyoos dhau los vim yog ntshav nce siab. Cov tee mob hauv lub sijhawm no dhau los tsawg dua. Txawm hais tias theem siab nce siab, nws tsis siab heev (ua ntej 180). tsis muaj ces sawv. "
2 xyoo dhau los, tus kws kho mob tau hais nrog Lizoril, tus mob tam sim no yuav luag tsis ua siab phem, qhov tseem ceeb tshaj plaws, tsis muaj qhov ua kom yuag ntxiv. siab, thiab ua ntej ntawd kuv feem ntau tsis nco qab vim qhov no. Tawv rog yog tswj tau. Kuv txaus siab. "
Anna, hnub nyoog 58 xyoo, St. Petersburg: “Kuv tau siv cov tshuaj mus li rau lub hlis (nrog kev tswj hwm tus kheej). Theem qib siab tau rov qab los li qub. Hloov cov tshuaj, Tab sis kuv nyiam cov tshuaj vim tias tsis muaj kev mob tshwm sim thiab nws yooj yim rau nws noj ib hnub ib zaug. "
