Latren belongs rau cov pab pawg ntawm cov tshuaj tiv thaiv peripheral vasodilators. Nws yog siv hauv kev kho mob kom ua tiav cov nyhuv vasodilating. Xws li cov txiaj ntsig kho tau yog qhov tsim nyog los rov qab ua kom cov ntshav ncig hauv cov nqaij mos thiab ua kom thaj chaw muaj ntshav. Cov tshuaj pab ua kom tshem tawm cov mob thrombosis, atherosclerosis thiab kev cuam tshuam ntawm cov choroid ntawm ocular hloov.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Pentoxifylline.
Latren pab tshem tawm thrombosis, atherosclerosis thiab cuam tshuam ntawm choroid ntawm ocular hloov.
ATX
C04AD03.
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm kev daws rau kev npaj ntawm Txoj kev lis ntshav. Daim ntawv tsuas tshuaj yog hauv iav ampoules muaj 100, 200 lossis 400 ml ntawm cov nquag sib txuas - pentoxifylline. Visually, qhov kev daws teeb meem yog cov kua pob tshab ntawm qhov xim daj me ntsis lossis tsis muaj kob. Raws li cov khoom siv ntxiv los txhim kho kev nqus, cov kua dej ua kua sodium lactate, dej tsis huv rau kev txhaj tshuaj, poov tshuaj thiab sodium chloride, calcium chloride siv.
Pharmacological kev txiav txim
Pentoxifylline yog synthesized los ntawm methylxanthine nws yog nyob rau pawg ntawm peripheral vasodilators. Pharmacological cov yam ntxwv yog vim qhov tsis muaj phosphodiesterase. Nyob rau tib lub sijhawm, cov tshuaj ua rau cov tshuaj lom neeg ua rau kom muaj kev txuam nrog ntawm 3,5-AMP hauv cov leeg nqaij ntawm cov leeg voos endothelium, cov qe ntshav, nyob rau hauv cov ntaub so ntswg thiab hloov khoom nruab nrog.
Pentoxifylline tiv thaiv qhov kev nplaum ntawm cov ntshav liab thiab cov ntshav ntshav, muab cov elasticity thiab nce qhov tsis kam ntawm lawv cov cell nyias. Vim tias cov qeeb ntawm kev sib sau ua ke, cov ntshav viscosity tsawg dua, cov nyhuv fibrinolytic nce thiab cov rheological ntawm cov ntshav txhim kho.
Txais tos Latrena ua rau muaj qhov zoo ntawm lub plawv dhia.
Pentoxifylline pab txhawb kev nce siab hauv ntshav ntshav fibrinogen. Hauv qhov no, cov tshuaj nquag txo qhov kev tawm tsam tag nrho hauv cov hlab ntsha ntu, muaj cov nyhuv vasodilating tsis muaj zog hauv cov leeg ntshav. Siv cov tshuaj pab ua rau lub plawv dhia tau li qub. Raws li kev ua tiav los ntawm kev ua kom zoo, ntshav microcirculation nyob rau hauv ischemic aav nce: qhov ntxim nyiam ntawm kev tsim oxygen oxygen tshaib plab ntawm cov hlwb poob qis, cov ntaub so ntswg tau txais txaus cov pa thiab cov khoom noj muaj txiaj ntsig.
Hauv cov chav kawm tshawb nrhiav, cov txiaj ntsig zoo ntawm cov tshuaj ntawm lub txaj capillary hauv qhov mob siab, lub hauv nruab nrab lub paj hlwb, thiab cov nyhuv nruab nrab ntawm cov hlab ntsha hauv lub raum tau kaw. Cov tshuaj muaj qhov tsis muaj zog ntawm kev nthuav dav ntawm cov hlab ntsha coronary.
Cov Tshuaj Pharmacokinetics
Thaum pentoxifylline nkag mus rau hauv cov hlab ntshav, nws nce mus txog nws qhov siab tshaj plaws hauv qhov ntshav hauv 60 feeb. Nyob rau ntawm thawj tshooj dhau los ntawm hepatocytes, cov tshuaj nquag muaj nyob hauv kev hloov pauv tiav. Cov khoom ua kom lwj siab tshaj qhov ntshav siab tshaj plaws ntawm pentoxifylline los ntawm 2 zaug thiab muaj cov nyhuv kho kom zoo. Ib nrab-lub neej yog 1.6 teev. 90% ntawm cov tshuaj tawm hauv lub cev hauv daim ntawv ntawm metabolites, 4% yog dhau nrog cov quav hauv nws thawj daim ntawv.
Kev ntsuas rau siv
Pentoxifylline yog vasodilator uas txhim kho cov haujlwm ua haujlwm ntawm cov hlab ntsha. Cov tshuaj yuav pab ua kom muaj kev ntxhov siab cov nqaij ntshiv ntawm cov hlab ntshav, bronchospasm. Tus vasodilator yog kho rau kev mob hauv lub plab retina ntawm lub qhov muag tiv thaiv keeb kwm yav dhau los ntawm kev hloov pauv ntawm cov leeg endothelium nyob rau hauv lub qhov muag. Cov tshuaj pab ua kom ntshav nce siab hauv thaj chaw ntawm qhov mob trophic lossis mob tob tob ntawm qhov qis qis.
Cov tshuaj pab nyob rau hauv kev kho mob ntawm occlusive kab mob ntawm peripheral hlab ntsha ntawm ntshav qab zib thiab atherosclerotic etiology, xws li:
- ua txhaum ntawm trophic ntaub so ntswg;
- mob hauv cov leeg ntawm leeg ntshav ntawm so;
- sib cav claudication;
- varicose leeg.
Cov tshuaj thim rov qab lub hlwb thiab cov ntshav xa mus rau cov khoom hauv nruab siab, pab tshem tawm thrombosis thiab txhim kho trophic cov hlab ntaws ua rau muaj mob ntshav qab zib polyneuropathy. Cov tshuaj yog siv los kho Raynaud's syndrome.
Cov Yuav Tsum Muaj
Cov tshuaj yog txwv tsis pub siv rau cov neeg uas muaj lub siab ntev mus rau qhov tshuaj uas ua rau lub hauv paus ntawm Latren, thiab xanthine derivatives. Cov tshuaj tsis pom zoo rau siv nyob rau hauv muaj cov kab mob thiab pathologies li nram no:
- kev los ntshav hnyav;
- hemorrhagic diathesis;
- predisposition rau txoj kev loj hlob lossis qhov muaj ntawm myocardial infarction;
- porphyrin kab mob;
- retinal hemorrhage;
- pathological lub plawv atherosclerosis cuam tshuam;
- mob atherosclerotic hloov ntau ntxiv nyob rau hauv endothelium ntawm cov hlab ntshav siab thiab ntshav hlab plawv;
- tsis tshua muaj ntshav siab;
- nqaij hlav ntshav tawm.
Cov tshuaj tsis pom zoo rau cov neeg muaj lub siab thiab lub raum tsis ua haujlwm.
Nrog saib xyuas
Cov tib neeg kev txom nyem los ntawm ulcerative-erosive lesions ntawm lub plab thiab duodenum yuav tsum tau saib xyuas lub xeev ntawm cov txheej txheem pathological thaum kho nrog Latren. Ceev faj yog pom zoo rau cov neeg muaj lub plawv tsis ua haujlwm thiab nyob rau hauv muaj ntshav qab zib mellitus. Cov tshuaj yog tshuaj nyob rau hauv kev saib xyuas mob nruj tom qab kev phais mob ntau.
Yuav ua li cas noj Latren
Cov tshuaj yog muab rau hauv cov tshuaj kom sai raws li txoj kev lis ntshav. Qhov ntau npaum li cas yog tsim los ntawm tus kws kho mob mus kawm rau ntawm qhov kev kawm ntawm cov txheej txheem pathological thiab tus neeg mob yam ntxwv. Cov tom kawg suav nrog lub cev qhov hnyav, hnub nyoog, kab mob concomitant, kam rau tshuaj, qhov mob ntawm cov mob ntshav tsis txaus.
Cov neeg mob uas muaj 12 xyoos rov saud raug nquahu kom muab ib rab lwg nrog 100-200 ml ntawm cov tshuaj. Qhov kev tswj hwm nrog rau txuas ntxiv yog txuas ntxiv rau 1.5-3 teev. Nrog kev ua siab ntev zoo, kev siv tshuaj ntxiv nce txog 400-500 ml (sib haum rau 300 mg) rau kev txhaj tshuaj yog tso cai.
Qhov siab tshaj plaws tau tso cai noj tshuaj ib hnub twg tau nce mus txog 500 ml. Qhov nruab nrab, kev siv tshuaj kho mob kav ntev li 5-7 hnub. Yog tias tsim nyog, kev kho mob txuas ntxiv yog hloov mus rau kev tswj hwm ntawm vasodilators hauv cov ntsiav tshuaj.
Nrog ntshav qab zib
Cov tshuaj muaj peev xwm txhim kho cov nyhuv hypoglycemic ntawm cov tshuaj tiv thaiv kab mob, yog li ntawd, thaum kho nrog Latren, nws yog qhov tsim nyog los tswj qib hauv qabzib hauv cov ntshav thiab nqa suab thaj. Qhov tom kawg yog qhov tsim nyog los tiv thaiv kev txhim kho hypoglycemia.
Sab Sij Huam Latrena
Kev phiv tshuaj tshwm sim nrog kev siv tshuaj tsis raug.
Ntawm ib feem ntawm cov khoom hauv nruab nrog kev pom
Tej zaum ib qho kev poob qis hauv qhov pom tseeb, qhov mob ntawm lub qhov muag, mob pob txha nqaj qaum, ua raws li kev tso tawm. Tsis tshua muaj neeg pom, qhov muag pom kev tsis meej yog nrog txoj kev loj hlob ntawm scotoma.
Los ntawm cov leeg nqaij thiab pob txha sib txuas
Hauv qee kis, mob leeg tsis muaj zog thiab hnov mob.
Kev kho mob txoj hnyuv
Nrog tus mob plab zom mov, tus neeg yuav pib hnov mob plab, xeev ntuav. Tsawg tsawg zaus, kev ua txhaum txoj hnyuv, ua rau lub siab ua rau lub plab, cholecystitis worsens. Cov tsos mob ntawm cholestasis yog ua tau.
Hematopoietic plab hnyuv siab raum
Kev txwv tsis pub cov leeg ntshav hematopoiesis nrog cov ntshav liab thiab ntshav muaj tsawg, tuaj yeem ua rau muaj kev loj hlob ntawm hypoplastic anemia. Nyob rau hauv cov mob hnyav, muaj kev pheej hmoo tuag.
Nruab nrab hauv lub paj hlwb
Nrog rau cov tshuaj tsis ncaj ncees lawm, lub taub hau pib hnov zoo li kiv taub hau, muaj mob taub hau, hnov qab, mob plab, pw tsaug zog. Tus tib neeg hnov kev ntxhov siab vim li cas.
Los ntawm lub tshuab ua pa
Tej zaum muaj kev ua pa txog siav.
Ntawm ib sab ntawm daim tawv nqaij
Cov tawv nqaij ua xua nrog cov pob liab liab, khaus, mob erythema thiab Stevens-Johnson. Lub fragility ntawm cov ntsia hlau phaj yog kho kom zoo.
Los ntawm cov hlab plawv system
Tus neeg mob pib hnov zaws, o ntawm cov nqaj. Muaj tachycardia, kev hloov pauv hauv ntshav siab. Nyob rau hauv cov mob hnyav, los ntshav yuav pib.
Los ntawm ib sab ntawm cov metabolism
Tej zaum qhov kev txhim kho ntawm tsis nco qab, qhov txo qis ntawm cov poov tshuaj qib siab, tawm hws thiab lub cev kub nce ntxiv, cov haujlwm ntawm daim siab enzymes nce.
Kev ua xua
Kev ua xua tau nrog cov tawv nqaij thiab khaus khaus tawm nrog cev.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Hauv kev pom ntawm qhov yuav tshwm sim txo qis dua ntawm lub zog ntawm lub hlwb psychomotor cov tshuaj tiv thaiv thiab qhov tsis hnov lus zoo thaum lub sij hawm kho cov tshuaj, nws yog ib qho tsim nyog yuav tsum tsis kam tsav tsheb thiab cov cuab yeej ua haujlwm.
Cov lus qhia tshwj xeeb
Yog hais tias lupus erythematosus thiab lwm yam kab mob pathologies ntawm cov ntaub so ntswg sib txuas, nws yog qhov yuav tsum tau muab tshuaj rau tom qab ua tiav kev soj ntsuam ntawm cov txiaj ntsig thiab txaus ntshai. Yuav tsum tau tso ntshav kuaj ntshav tsis tu ncua vim qhov muaj feem yuav ua kom mob ntshav tsis txaus.
Cov neeg mob uas muaj lub plawv tsis ua haujlwm ntev yuav tsum mus txog theem ntawm txoj kev them nyiaj ib ntus ua ntej siv cov tshuaj.
Cov neeg mob predisposed rau kev loj hlob ntawm anaphylactic kev hloov kho yuav tsum tau soj ntsuam kuaj rau ua siab ntev rau cov tshuaj. Yog tias pom tias muaj qhov tshwm sim zoo, kev noj tshuaj raug muab tso tseg.
Siv rau lub sijhawm qub
Cov neeg laus dua 50 xyoo yuav tsum xyuam xim.
Qhia Ntawv Latren rau menyuam yaus
Cov me nyuam tsis tau muaj 12 xyoos feem ntau tsis tshua pom zoo los kho cov tshuaj Latren. Rau cov menyuam yaus, nws yog qhov tsim nyog los laij qhov ntau npaum li cas nyob ntawm lub cev qhov hnyav - 10 ml ntawm cov tshuaj rau 1 kg ntawm qhov hnyav. Rau cov menyuam tshiab, qhov kev noj tshuaj txhua hnub tau muab xam zoo ib yam nkaus, tab sis qhov siab tshaj plaws yuav tsum tsis pub tshaj 80-100 ml.
Siv thaum cev xeeb tub thiab lactation
Tsis muaj cov ntaub ntawv hais txog qhov ua rau nkag mus ntawm pentoxifylline thiab nws cov nyhuv ntawm kev txhim kho embryonic. Yog li ntawd, txoj kev tso ntshav ib leeg tsuas yog raug rau hauv kev mob hnyav, thaum cov nyhuv vasodilating ntawm cov tshuaj tuaj yeem tiv thaiv kev hem thawj rau lub neej ntawm leej niam. Cov txiaj ntsig kho yuav tsum dhau qhov kev pheej hmoo ntawm intrauterine txawv txav ntawm lub cev.
Thaum pub niam mis, thaum teem caij Latren, nws yog ib qho tsim nyog yuav tsum tsis txhob pub mis.
Daim ntawv thov rau lub raum khiav tsis zoo
Kab mob hauv lub raum nce ntxiv ib nrab-lub neej ntawm cov tshuaj, yog li ntawd, txoj kev tso dej ntawm Latren tso cai tsuas yog nyob ntawm qhov muaj mob me thiab mob raum.
Siv rau lub siab ua haujlwm tsis zoo
Cov tshuaj tsis tso cai rau siv los ntawm cov neeg muaj kev mob siab rau daim siab.
Latren Tshem Tsis Txaus
Nrog kev quav yeeb tshuaj, cov tsos mob hauv qab no tsim:
- leeg tsis muaj zog;
- Kiv taub hau
- neuromuscular arousal;
- poob hauv cov ntshav siab;
- tsis meej pem thiab tsis nco qab;
- nce lub plawv dhia;
- ntws tawm ntawm lub ntsej muag;
- ntuav thiab xeev siab;
- los ntshav thiab hemorrhage mus rau hauv cov kab noj hniav ntawm lub plab zom mov;
- mob leeg;
- npaws.
Tus neeg raug mob yuav tsum tau mus pw hauv tsev kho mob sai. Txoj kev kho yog txhawm rau tiv thaiv kev txhim kho ntawm kev los ntshav sab hauv thiab tshem tawm cov paib ntau dhau.
Kev cuam tshuam nrog lwm yam tshuaj
Pentoxifylline tuaj yeem ua rau poob qis hauv plasma qab zib concentration thaum siv cov tshuaj hypoglycemic lossis insulin. Yog li, cov neeg mob ntshav qab zib yuav tsum sab laj nrog endocrinologist los kho cov tshuaj ntau ntawm cov tshuaj tiv thaiv kab mob ntshav qab zib.
Hauv kev xyaum ua haujlwm tom qab muag, tau muaj cov xwm txheej ntawm txo ntshav coagulability nrog kev siv cov tshuaj tiv thaiv antivitamins K, siv tshuaj tua kab mob ncaj qha thiab tsis ncaj nrog Latren. Thaum ua ke nrog cov tshuaj no, kev saib xyuas ntawm kev ua haujlwm anticoagulant yog qhov tsim nyog.
Pentoxifylline ua rau txoj kev tiv thaiv kev tiv thaiv tsis zoo ntawm cov tshuaj antihypertensive. Raws li qhov tshwm sim, txoj hlab ntshav hypotension yuav tshwm sim.
Kev pom lub cev tsis sib xws yog pom thaum sib xyaw Latren nrog lwm cov tshuaj hauv tib lub koob txhaj.
Cov tshuaj yeeb dej caw muaj zog nce qib ntawm Theophylline, uas yog vim li cas exacerbation lossis nce qhov ntau zaus ntawm cov tsos ntawm kev tsis zoo los ntawm kev siv Theophylline.
Cawv tau zoo
Cov tshuaj tsis tuaj yeem nrog cov tshuaj ethanol uas muaj cov tshuaj yeeb thiab dej cawv. Kev haus dej cawv ethyl yog qhov ua yeeb yam ntawm pentoxifylline, txhawb kev ua kom cov nplaum ntawm cov ntshav liab, inhibition ntawm cov ntshav ncig. Ethanol ua rau vasospasm thiab kev loj hlob ntawm thrombosis. Muaj ib qho tsis muaj qhov ua kom zoo thiab ua kom tsis muaj zog.
Analogs
Analogues ntawm cov tshuaj uas muaj cov yam ntxwv zoo ib yam los sis tshuaj lom neeg:
- Trental;
- Bilobil;
- Pentoxifylline;
- Paiv Xyooj;
- Agapurin;
- Pentilin.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Cov tshuaj tsis tuaj muag muag yam tsis muaj kev qhia ncaj qha rau kev kho mob.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Yuav tsum tau ntawv kho mob vim tias muag Latren muag dawb. Kev siv tshuaj tsis tseeb ntawm cov vasodilator tuaj yeem ua rau kom dhau kev noj tshuaj ntau dhau lossis muaj kev phiv loj heev.
Nqi
Tus nqi nruab nrab ntawm txoj kev daws teeb meem txawv ntawm 215 txog 270 rubles.
Cia rau cov neeg mob rau cov tshuaj
Nws yog ib qho tsim nyog yuav tsum tau khaws cov tshuaj ntawm qhov kub ntawm + 2 ... + 25 ° C hauv qhov chaw qhuav, cais tawm ntawm tshav ntuj.
Hnub tas sij hawm
2 xyoos
Chaw tsim tshuaj paus
Yuri-Farm LLC, Russia.
Xyuas
Ulyana Tikhonova, 56 xyoo, St.
Muab ib qho kev daws rau thrombosis. Thaum xub thawj, Latren cov neeg tawm mus nrog tau cov tshuaj heparin, tom qab ntawd lawv raug pauv mus rau kev noj tshuaj. Txoj kev lis ntshav pab yaj cov ntshav txhaws, o tuaj ploj mus. Kuv xav tias qhov zoo ua ke ntawm nqe thiab zoo. Tsis muaj kev mob tshwm sim, tab sis kuv yuav tsum tso dej cawv thiab haus luam yeeb thaum kho. Tus kws kho mob tau hais kom nruj me ntsis cov lus qhia rau kev siv kom txo qhov muaj feem ntau ntawm cov teeb meem kev noj qab haus huv.
Leopold Kazakov, 37 xyoo, Ryazan
Kuv tau sau tshuaj rau Latren los ntawm tus kws kho mob otolaryngologist, rau tus neeg kuv tsis txaus siab txog qhov tsis hnov lus zoo thiab qhov pom ntawm nrov tinnitus. Qhov laj thawj yog kev txhim kho ntawm dystonia. Infusions pab tshem tawm qhov mob taub hau, suab nrov hauv pob ntseg. Kuv pom tias tsis pom kev zoo yog qhov qub. Qhov tshwm sim tshwm sim nyob rau hauv daim ntawv ntawm txos ntshav siab. Yuav kom tshem tawm lawv, yuav tsum tau txo tshuaj ntau npaum. Tus kws kho mob uas koom nrog yuav tsum hloov pauv. Kuv tsis qhia koj kom kho qhov tsuas tshuaj rau koj tus kheej, vim tias muaj kev pheej hmoo ntawm kev noj ntau dhau thiab ntau yam kev tshwm sim tsis zoo hauv lub cev.