Ofloxin 400 yog siv tshuaj yaj yeeb hauv cov pab pawg fluoroquinolone. Nws muaj cov nyhuv antimicrobial.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
INN - Ofloxacin.
Ofloxin 400 yog siv tshuaj yaj yeeb hauv cov pab pawg fluoroquinolone.
Ath
J01MA01.
Tso cov ntawv thiab cov nyob ua ke
Ib hom tshuaj yog tsim nyob hauv ntau hom: ntsiav tshuaj, tshuaj pleev, tshuaj ntsiav, tee thiab tov. Cov tshuaj yeeb dej caw hauv txhua daim ntawv yog ofloxacin, quinolone ntawm tiam thib ob.
Ntsiav tshuaj
Lawv muaj kev tiv thaiv los ntawm lub plhaub thiab muaj cov khoom xyaw nquag hauv qhov khoom ntawm 400 mg thiab 200 mg. Ntxiv cov khoom xyaw:
- mis nyuj qab zib;
- pob kws nplej siab;
- talc;
- hypromellose 2910/5.
Ntim hauv ntsiav tshuaj ntawm 10 pcs. hauv hlwv.
Ncos
Ua tau ob hom tee: qhov muag thiab pob ntseg. Cov tshuaj tau nthuav tawm nyob rau hauv daim ntawv ntawm cov tshuaj tov, hauv 1 ml ntawm uas muaj:
- 3 mg ofloxacin;
- saline daws;
- benzalkonium chloride;
- hydrogen chloride;
- npaj dej.
Cov tshuaj hauv cov ntawv ua kua yog hliv rau hauv hwj yas. Tso tsheb hlau luam muaj nruab nrog poob.
Ua tau ob hom tee: qhov muag thiab pob ntseg.
Hmoov
Daim ntawv tso tawm ofloxacin tsis tuaj.
Tshuaj
Kev daws yog npaj rau Txoj kev lis ntshav. Nws muaj cov xim daj ntshiab-ntsuab. Cov tshuaj yog hliv rau hauv vials hauv ib qhov nyiaj ntawm 100 ml. Ntxiv nrog rau cov tshuaj nquag, muaj ntxiv:
- saline daws;
- Trilon B;
- hydrogen chloride;
- lim dej.
Cov tshuaj ntsiav
Daim ntawv ntawm cov tshuaj no tau nthuav tawm nyob rau hauv daim ntawv ntawm daj ntseg ua ke ua ke. Muaj pes tsawg leeg:
- ofloxacin - 200 mg;
- hypromellose;
- sodium lauryl sulfate;
- mis nyuj qab zib;
- calcium phosphate bisubstituted anhydrous;
- talcum hmoov.
Cov tshuaj no kuj tau nthuav tawm nyob rau hauv daim ntawv ntawm daj gelatin tsiav tshuaj.
Tshuaj pleev
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm tshuaj pleev ntawm 2 hom: rau kev kho mob ntawm qhov txhab thiab rau kev kho mob ntawm lub qhov muag. Ofloxacin, npaj rau daim ntawv thov rau ntawm daim tawv nqaij, muag hauv cov hlab 15 lossis 30 g. 1 g ntawm cov tshuaj muaj cov tshuaj hauv qab no:
- 1 mg ofloxacin;
- 30 mg lidocaine hydrochloride;
- propylene glycol;
- poloxamer;
- macrogol 400, 1500, 6000.
Qhov muag tshuaj pleev qhov muag muaj nyob rau hauv cov hlab ntawm 3 thiab 5 g.
- ofloxacin - 0.3 g;
- nipagin;
- nipazole;
- roj av jelly.
Cov tswm ciab
Hauv ntau cov npe lag luam, lub paum xav ua yog ua.
Pharmacological kev txiav txim
Cov tshuaj muaj cov kab mob bactericidal uas tshwm sim los ntawm inhibition ntawm DNA gyrase (cov no yog cov enzymes uas ua lub luag haujlwm ntawm synthesis ntawm DNA hauv cov hlwb ntawm microflora pathogenic thiab lawv kev tsim tawm, thiab tseem koom nrog cov txheej txheem tseem ceeb tshaj plaws: sib ntswg lub kauv thiab ua kom nws ruaj khov).
Cov tshuaj muaj cov kab mob bactericidal uas vim yog inhibition of DNA-gyrase.
Fluoroquinolone rhuav tshem lub plhaub pathogenic microflora, yog li qhov ua tau los ntawm kev txhim kho cov ntaub ntawv tiv taus yog qhov tsawg heev. Cov tshuaj qhia cov kev ua haujlwm siab tshaj plaws hauv kev sib raug zoo rau cov kab mob gram-negative. Ofloxacin, piv nrog cov tshuaj tua kab mob Ciprofloxacin, tseem ua haujlwm thaum ua ke nrog kev siv tshuaj tiv thaiv ntawm RNA polymerase synthesis.
Cov tshuaj nquag ua haujlwm ntawm cov tshuaj rhuav tshem cov kev sib txuas ntawm cov DNA pab, ua rau cov cell ntawm cov microorganism tuag. Ua tsaug rau qhov kev txiav txim ntawm cov tshuaj no, nws yog siv los tawm tsam ntau cov kab mob ntawm cov kab mob uas tiv taus lwm hom tshuaj tua kab mob thiab sulfonamides.
Cov Tshuaj Pharmacokinetics
Cov tshuaj sai thiab nrawm nyob rau hauv txoj hnyuv, qhov siab tshaj plaws ntawm Ofloxacin hauv cov ntshav ntshav tau pom tom qab 1-3 teev. Kev tshem tawm ib nrab-lub neej yog 5-10 teev, uas yog kev tshwm sim ntawm cov tshuaj uas tuaj yeem siv tau 1-2 zaug ib hnub. Kwv yees li 75-90% ntawm cov tshuaj tawm hauv lub cev nrog zis.
Kev ntsuas rau siv
Ofloxacin yog siv los kho cov txheej txheem kis:
- cov kab mob zis;
- poj niam thiab txiv neej qhov chaw mos;
- Kab Mob STI
- txoj hnyuv;
- lub plab hauv plab thiab txoj hnyuv;
- biliary system;
- nosocomial thiab postoperative;
- ua pa;
- septicemia thiab bacteremia;
- Nruab nrab cev;
- tuberculosis, mob ruas.
Tshuaj pleev yog qhia rau kev kho mob ntawm daim tawv nqaij, kab mob hniav thiab mob txhab.
Cov Yuav Tsum Muaj
Cov tshuaj muaj cov nram qab no contraindications:
- lub cev tsis haum rau Cheebtsam;
- cev xeeb tub thiab kab mob siab B;
- cov menyuam yaus hnub nyoog qis dua 18 xyoo;
- qaug dab peg thiab cerebral qaug dab peg (tom qab mob caj dab craniocerebral thiab hlab ntsha tawg);
- cov ntsiab lus siab ntawm urea;
- kev puas tsuaj rau cov leeg uas tau tshwm sim thaum noj fluoroquinolones;
- tsis muaj cytosolic enzyme (G6FD).
Nrog saib xyuas
Cov lus qhia rau kev siv qhia tias thaum sau tshuaj, yuav tsum ceev faj rau hauv cov neeg mob uas muaj cov kab hauv qab no:
- cerebral arteriosclerosis;
- circulatory mob cuam tshuam ntawm lub paj hlwb;
- lub raum tsis ua haujlwm (nrog creatinine tshem tawm ntawm 50-20 ml / min);
- kev txawv txav ntawm kev txhim kho thiab mob ntawm lub hauv nruab nrab lub paj hlwb;
- lub siab tsis ua hauj lwm nrog lub sijhawm QT ntev.
Yuav ua li cas noj Ofloxin 400
Rau cov neeg mob neeg laus, qhov ntau npaum ntawm cov tshuaj yog 200-600 mg. Txais tos txhuas nyob hauv 7-10 hnub. Cov tshuaj hauv ib koob tshuaj 400 mg tuaj yeem noj ib zaug. Cov ntsiav tshuaj tsis tuaj yeem zom, lawv yuav tsum nqos tag nrho, ntxuav nrog qhov tsim nyog ntawm cov dej. Yog tias muaj mob hnyav thiab rog dhau, ntau npaum ntawd yuav ntau txog 800 mg rau ib hnub.
Hauv kev kho mob ntawm cov kab mob pathologies ntawm cov qis dua ntawm cov kab mob tso zis ntawm daim ntawv tsis haum, lawv raug coj 200 mg ib hnub ib zaug, qhov kawm ntev li 3-5 hnub. Txog kev kho kab mob gonorrhea, cov tshuaj yuav qaug ib zaug ib zaug ntawm 400 mg.
Thaum twg tsis koob tshuaj
Yog tias vim qee qhov laj thawj tus neeg mob tsis tuaj yeem noj tshuaj, ces koj tuaj yeem haus nws haus sai li uas tus neeg nco qab qhov no.
Nrog ntshav qab zib
Cov neeg mob uas mob ntshav qab zib pathology thaum kho nrog Ofloxin yuav tsum soj ntsuam kev nce siab ntawm cov piam thaj hauv cov ntshav, vim tias Kev tswj hwm kev sib koom tes ntawm cov tshuaj muaj suab thaj txo cov tshuaj, insulin thiab fluoroquinolones tuaj yeem ua rau txhim kho hypo- lossis hyperglycemia.
Cov neeg mob ntshav qab zib pathology thaum kho nrog Ofloxin yuav tsum saib xyuas cov ntshav qabzib hauv cov ntshav.
Qhov tshwm sim ntawm inloxine 400
Thiab txawm hais tias cov kev mob tshwm sim tsis tshua muaj tshwm sim, yog tias lawv pom, tus neeg mob yuav tsum sab laj nrog kws kho mob.
Kev kho mob txoj hnyuv
Cov tsos mob hauv qab no tshwm sim:
- mob thiab tsis xis nyob hauv plab;
- mob dyspeptic;
- plab hnyuv siab;
- dysbiosis;
- tsis hnov qab;
- kab mob siab.
Hematopoietic plab hnyuv siab raum
Saib:
- anemia
- leukopenia;
- pancytopenia;
- cov nqaij hem;
- thrombocytopenia.
Nruab nrab hauv lub paj hlwb
Cov tsos mob tshwm sim nrog lub hauv nruab nrab lub paj hlwb puas:
- Kiv taub hau
- mob taub hau
- Ntxhov siab vim
- kev pw tsaug zog;
- kev xav thiab phobias;
- nce siab intracranial;
- ua kom pom tseeb;
- nyuaj siab lub xeev.
Los ntawm cov leeg musculoskeletal
Saib:
- tendonitis;
- nqaij leeg;
- cov txheej txheem mob hauv cov cuab yeej sib txuas-ligamentous;
- leeg tsis muaj zog thiab mob mob.
Los ntawm lub tshuab ua pa
Yog tsis tuaj.
Ntawm ib sab ntawm daim tawv nqaij
Tsom xam: petychia, ua pob liab vog thiab mob tawv nqaij.
Los ntawm genitourinary system
Cov kev mob tshwm sim tsis tshua muaj tshwm sim:
- hypercreatininemia;
- jade;
- nce hauv urea.
Los ntawm cov hlab plawv system
Cov neeg mob tuaj yeem tsim kho:
- kev ntaus lub siab tuaj;
- txo hauv cov ntshav siab;
- tachycardia;
- leeg mob vascular;
- cev qhuav dej kev loj hlob.
Endocrine system
Yog tsis tuaj.
Kev ua xua
Kev tawm tsam tsis haum yog pom los ntawm cov tsos mob hauv qab no:
- ua pob;
- khaus
- txog siav
- kev tsis haum nephritis;
- o rau lub ntsej muag thiab caj dab;
- kev ua xua rau mob ntsws;
- Quincke's edema;
- anaphylactic poob siab.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Thaum lub sij hawm kho mob nrog Ofloxin, nws yog txwv tsis pub tsav lub cev muaj zog thiab cov txheej txheem nyuaj.
Cov lus qhia tshwj xeeb
Cov tshuaj yuav tsis ua hauj lwm zoo rau kev kho cov kab mob pathologies, txoj kev txhim kho uas tau cuam tshuam los ntawm pneumococci lossis mycoplasmas: ib daim ntawv uas ua rau mob ntsws thiab mob ntsws.
Xws li kev tsim cov kev qhia rau tshuaj tiv thaiv ua xua, qhov tsis zoo cuam tshuam txog lub hauv nruab nrab lub paj hlwb, nws yog qhov yuav tsum thim cov tshuaj.
Siv thaum cev xeeb tub thiab lactation
Cov tshuaj no yog txwv rau kev siv los ntawm cov poj niam lub sijhawm lub sijhawm ua menyuam thiab lactation vim txoj kev loj hlob ntawm pathologies ntawm cov pob qij txha thiab cov leeg nqaij hauv tus menyuam.
Daim ntawv yuav tshuaj ntawmloxine rau 400 tus menyuam
Cov neeg mob hnub nyoog qis dua 18 xyoo tsis tau teev cov tshuaj noj, vim tias koj yuav tsum tau tos rau qhov ua tiav ntawm kev loj hlob thiab kev tsim ntawm cov leeg ua haujlwm. Tab sis yog tias tsim nyog, thiab nyob rau hauv kev saib xyuas ntawm tus kws kho mob, Ofloxacin tuaj yeem raug muab tshuaj ntawm 7.5 mg rau 1 kg ntawm qhov hnyav. Kev tso cai ntau tshaj yog 15 mg / kg.
Cov neeg mob hnub nyoog qis dua 18 xyoo tsis tau teev cov tshuaj noj, vim tias koj yuav tsum tau tos rau qhov ua tiav ntawm kev loj hlob thiab kev tsim ntawm cov leeg ua haujlwm.
Siv rau lub sijhawm qub
Siv tshuaj tua kab mob nrog ceev faj vim muaj kev hloov pauv ntawm lub hnub nyoog thiab qhov kev pheej hmoo ntawm kev tshwm sim tsis zoo.
Daim ntawv thov rau lub raum khiav tsis zoo
Qhov yuav tsum tau hloov kho ntau npaum li cas, thiab kev kho yog ua raws li kev saib xyuas ntawm tus kws kho mob.
Siv rau lub siab ua haujlwm tsis zoo
Cov tshuaj yog siv nyob rau hauv qhov xwm txheej uas tus neeg mob yuav soj ntsuam cov tshuaj lom biliburin kom tsis tu ncua, thiab yog tias cov kua tsib muaj xim ntau ntxiv, ces ntau qhov hloov kho lossis cov tshuaj kom thim tag nrho.
Ofloxin 400 Overdose
Cov tsos mob li nram no ntawm intoxication yuav pib:
- mob dyspeptic;
- ntshav siab
- tsis meej pem.
Yog tias kuaj pom muaj tshuaj ntau dhau, cov tshuaj kom tsis ua haujlwm ntxiv, tus neeg mob ntxuav hauv plab hauv tsev kho mob. Yog tias raug rau mob hnyav, ua rau mob hemodialysis kho tau.
Kev cuam tshuam nrog lwm yam tshuaj
Cov tshuaj sib cuam tshuam sib txawv nrog lwm cov tshuaj.
Contraindicated kev sib txuas ua ke
Kev siv tib lub sijhawm ua haujlwm nrog cov tshuaj tua kab mob nrog rau cov tshuaj hauv qab no yog txwv:
- NSAIDs - kev tsis meej pem ntawm cerebral qaug zog yuav tsawg;
- quinolones thiab tshuaj mob nrog lub raum rov ua kom tiav - ofloxin qib nce thiab nws lub sijhawm ncua tau ntev;
- antihypertensive tshuaj, barbiturates - ntshav siab tuaj yeem nce siab;
- glucocorticoids - kev pheej hmoo ntawm cov leeg mob;
- anthocyanins - lub zom ntawm cov tshuaj tsawg dua.
Tsis pom zoo kev sib txuas ua ke
Ofloxacin sib raug zoo nrog cov tshuaj hauv qab no yog txwv:
- vitamin K antagonists - coagulation ntshav tuaj yeem nce ntxiv;
- Glibenkamid - ntshav ntau Glibenkamide qib tuaj yeem nce ntxiv;
- thaum lub sijhawm kuaj mob, vim yog cov tshuaj tua kab mob, tej zaum yuav muaj qhov tsis zoo tshwm sim ntawm opiates thiab porphyrins nyob rau hauv cov zis.
Tej kev sib txuam uas xav tau ceev faj
Nrog rau kev siv ua ke ntawm Ofloxacin nrog lub qhov ncauj anticoagulants, ib qho kev nce ntawm kev ua si ntawm tom kawg yog ua tau.
Nrog kev sib xyaw ua ke ntawm cov tshuaj tua kab mob nrog cov tshuaj uas ua txhaum cov kev phom sij siab, nws yog qhov tsim nyog los tswj lub ECG.
Cawv tau zoo
Cov tshuaj tsis siv nrog cawv.
Analogs
Ofloxacin muaj cov kev hloov hauv qab no:
- Ofaxin;
- Oflo;
- Phloxane;
- Oftagel;
- Ofor.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Los ntawm tshuaj.
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Tsis yog.
Tus nqi ntawm Ofloxin 400
Koj tuaj yeem yuav tshuaj nyob rau hauv Ukraine ntawm tus nqi ntawm 133.38-188 UAH., Thiab nyob hauv Russia - 160-180 rubles.
Cia rau cov neeg mob rau cov tshuaj
Khaws cov tshuaj tua kab mob hauv qhov chaw qhuav thiab tsaus kom tsis txhob ncav cuag cov menyuam. Qhov kub yuav tsum tsis pub tshaj 25 ° C.
Hnub tas sij hawm
Tsis ntev tshaj 3 xyoos.
Chaw tsim tshuaj paus
Czech koom pheej.
Ofloxin 400 Xyuas
Cov kws kho mob
Maxim, Moscow: "Hauv kuv txoj kev kho mob, Kuv siv cov fluoroquinolones los kho cov neeg mob. Ofloxacin, Kuv xav txog nws ua cov tshuaj kho tau zoo. Nws muab cov txiaj ntsig sai thiab tsis muaj txiaj ntsig, tsis muaj kev phiv tshuaj."
Galina, St. Petersburg: "Kuv tau ua haujlwm nyob rau hauv gynecology rau 10 xyoo. Rau qhov mob ntawm urogenital plab hnyuv siab raum, Kuv hais tawm Ofloxacin rau cov poj niam. Ntawm qhov zoo, daim ntawv tso tawm yooj yim, muaj peev xwm tswj hwm thiab tswj hwm kev noj tshuaj tuaj yeem sau tseg. Nws txaus los coj cov tshuaj 1-2 zaug ib hnub."
Thaum noj cov tshuaj, vascular yuav tshwm sim.
Cov neeg mob
Anna, 38 xyoo, Omsk: "Cov tshuaj no pab kho tus mob cystitis heev. Tom qab 2-3 hnub noj, qhov mob tau zoo zuj zus tuaj, vim tias cov tsos mob ntawm tus kab mob ploj. Tsis muaj kev phiv, txawm tias thawb tom qab siv tshuaj tua kab mob tsis yog."
Yuri, hnub nyoog 29 xyoo, Krasnodar: “Ib xyoos dhau los kuv tau khaub thuas tsis zoo thaum ua haujlwm, uas ua rau muaj teeb meem tso zis. Tus kws kho mob tau sau cov tshuaj no, uas kuv haus rau ib lub lim tiam. "
Tatyana, 45 xyoo, Voronezh: "Tus kws kho mob tom qab kev kuaj pom pom pom qhov mob ntsaws kabmob hauv kuv.
