Lyspro insulin yog ib yam khoom uas zoo li tib neeg insulin. Nws yog tsim rau cov neeg uas muaj kev tsis hnov qab cov piam thaj. Hauv cov kab mob no, hyperglycemia kev loj hlob vim yog cov tshuaj insulin tsis txaus.
Lub Npe Tsis Yog Neeg Tsis Muaj Npe
Cov Ntawv Teev Npe - lub npe lag luam ntawm cov tshuaj hauv Lavxias.
Lyspro insulin yog INN tshuaj.
Kev siv tshuaj insulin lispro - cov ntaub npuag xim.
Lyspro insulin yog ib yam khoom uas zoo li tib neeg insulin. Nws yog tsim rau cov neeg uas muaj kev tsis hnov qab cov piam thaj.
ATX
Txoj cai hauv lub cev anatomical thiab kho cov tshuaj siv tshuaj yog A10AB04. Cov pab pawg pawg code yog A10AB (luv luv ua yeeb yam insulins thiab lawv analogues).
Tso cov ntawv thiab cov nyob ua ke
Cov tshuaj yog tsim hauv cov kua ua rau kev txhaj tshuaj rau hauv txoj leeg lossis hauv qab daim tawv nqaij. Cov tshuaj mus muag nyob rau hauv 2 version:
- hauv pob ntawv los qhia nrog 5 Daim Ntawv Ceev Cov Hluav Taws Xob (3 ml txhua, 100 IU / ml), npaj siv;
- hauv daim thawv ntawv thawv nrog 5 daim cartridges (3 ml txhua, 100 IU / ml).
Cov tshuaj nquag hauv cov tshuaj hu ua lyspro insulin. Cov khoom siv ntxiv: metacresol, glycerol, dej rau txhaj tshuaj, 10% daws ntawm hydrochloric acid, thiab lwm yam.
Pharmacological kev txiav txim
Cov tshuaj muaj qhov ua kom tsis pom kev zoo. Tom qab tswj hwm dej los yog tshuaj hauv qab, txheej txheem cov ntshav qab zib hauv lub cev txo qis. Cov nyhuv no tshwm sim kwv yees li 10-20 feeb tom qab kev siv tshuaj.
Cov tshuaj muaj qhov ua kom tsis pom kev zoo. Tom qab tswj hwm dej los yog tshuaj hauv qab, txheej txheem cov ntshav qab zib hauv lub cev txo qis.
Cov Tshuaj Pharmacokinetics
Cov tshuaj muaj zog yog xam nrog hauv kev nrawm, vim nws muaj qhov nqus siab ntawm cov roj subcutaneous (nws yog ib feem ntawm ultra-luv-ua yeeb yam insulin pawg). Vim qhov no, hauv lub sijhawm luv luv qhov siab tshaj plaws nyob hauv ntshav tau tiav (yam tsawg ib nrab ib teev tom qab).
Cov tshuaj yuav tau txhaj rau hauv cov hlab ntsha lossis hauv qab tawv nqaij ua ntej noj mov. Nws raug tso cai muab kev txhaj tshuaj ua ntej, siv sijhawm ntev li 15 feeb ua ntej noj. Lub siab tshaj plaws ntawm kev ua haujlwm tshwm sim tom qab 1-3 teev, thiab lub sijhawm ntawm cov tshuaj yog los ntawm 3 txog 5 teev. Qhov kev tshem tawm ib nrab-lub neej yog kwv yees li 1 teev.
Kev ntsuas rau siv
Cov kws kho mob muab cov tshuaj rau lawv cov neeg mob ntshav qab zib. Nrog kev pab ntawm cov tshuaj no, kev kho mob insulin yog ua tiav, uas tso cai rau koj kom tswj cov piam thaj hauv cov ntshav hauv qhov kev nyab xeeb.
Cov Yuav Tsum Muaj
Cov tshuaj tsis tuaj yeem siv:
- nrog hypersensitivity rau cov nquag yam tshuaj los yog ntxiv rau ntxiv los ntawm cov Humalogue;
- nrog qhov txo qis hauv cov piam thaj hauv qab cov theem ib txwm (3.5 mmol / l).
Nrog saib xyuas
Nws yog ib qho tsim nyog yuav tsum tau ua tib zoo txhaj tshuaj subcutaneously kom tsis txhob nkag mus rau cov ntshav ntshav. Tom qab txhaj tshuaj, daim tawv nqaij tsis tas yuav tsum txhuam.
Yuav ua li cas noj tshuaj insulin lyspro
Cov yam ntxwv ntawm kev siv thiab ntau npaum li cas yuav tsum txiav txim siab los ntawm cov neeg kho mob ib tus zuj zus. Feem ntau, insulin yog muab tshuaj subcutaneously. Kev tswj hwm kev mob plab tej zaum yuav tsim nyog rau qee kis (piv txwv li, nyob rau lub sijhawm ntawm kev phais mob lossis tom qab lawv, nrog cov kabmob uas tshwm sim hauv cov qauv mob tsis txaus, insulin tsis muaj peev xwm thiab metabolism metabolism tsis txaus).
Thaum siv cov tshuaj, nws yog ib qho tseem ceeb kom ua raws li cov lus pom zoo rau kev qhia ntawm kev txhaj tshuaj. Tus neeg mob xav tau:
- Npaj tshuaj. Nws yuav tsum sib haum rau cov yam ntxwv xws li pob tshab, tsis muaj xim. Cov lus qhia ntawm kev daws daws tau muab pov tseg yog tias nws yog huab, ထူ. Cov tshuaj yuav tsum muaj chav sov.
- Ntxuav koj ob txhais tes thiab xaiv qhov chaw rau txhaj tshuaj subcutaneous los ntawm kev so nws.
- Muab rab koob tso rau ntawm daim duab xaum thiab tshem lub hau tiv thaiv ntawm nws.
- Ua ntej txhaj cov tawv nqaij rau ntawm qhov chaw xaiv kom sau, kom lub qhov ntau dua tau txais, lossis ncab.
- Ntxig lub koob tso rau hauv qhov chaw npaj thiab nias lub pob.
- Ua tib zoo tshem tawm rab koob ntawm daim tawv nqaij thiab siv paj rwb ntaws mus rau qhov chaw txhaj tshuaj.
- Siv lub hau tiv thaiv, tshem tawm rab koob. Lwm zaus koj siv cov tshuaj, koj xav tau koob tshiab.
Ib qho tsos mob tshwm sim thaum siv insulin lyspro yog hypoglycemia.
Phiv los ntawm insulin lyspro
Cov tsos mob tshwm sim feem ntau yog hypoglycemia. Hauv cov teeb meem loj, cov ntshav qab zib qis ua rau tsaus muag. Tsis tas li, muaj ntshav qab zib tsis muaj qab hau muaj kev pheej hmoo tuag.
Hauv kev siv tshuaj, koj yuav ntsib kev tsis haum tshuaj. Nws cov tsos mob tshwm sim feem ntau pom ntawm qhov chaw txhaj tshuaj. Hauv cov neeg mob, daim tawv nqaij liab thiab sawv pob, khaus tshwm sim. Cov tsos mob no yuav ploj mus tom qab ib pliag. Tsis tshua muaj qhov ua xua cuam tshuam rau tag nrho lub cev. Xws li lub cev tiv thaiv kab mob tuaj yeem tsim kev phom sij txog lub neej. Cov tsos mob ntawm kev tsis haum tshuaj:
- pob thoob plaws lub cev;
- khaus
- Quincke's edema;
- nce hws;
- poob hauv cov ntshav siab;
- nce lub plawv dhia;
- txog siav
- npaws.
Lwm qhov kev phiv ntxiv yog qhov ploj ntawm subcutaneous rog (lipodystrophy). Qhov no yog ib cov tshuaj tiv thaiv hauv zos. Nws tuaj yeem raug soj ntsuam ntawm ntu ntawm lub cev mus rau qhov kev txhaj tshuaj ntawm cov tshuaj tau muab coj los ua.
Cuam tshuam rau lub peev xwm los tswj cov tshuab
Ib qho tshuaj noj yuav cuam tshuam rau lub peev xwm ntawm kev tsav tsheb thiab ntau yam txheej txheem nyuaj uas xav tau kev nce siab thiab ceev faj, hauv 2 qhov xwm txheej:
- nrog kev qhia txog kev nce tshuaj lossis txo qis thiab kev txhim kho hyperglycemia lossis hypoglycemia vim qhov no;
- nrog cov tsos ntawm cov ntshav qog ua ib qho kev mob tshwm sim.
Hauv ob qho xwm txheej, muaj peev xwm mloog zoo yog qhov tsis hnov lus, thiab lub hlwb psychomotor qeeb qeeb. Tsav tsheb thiab ua haujlwm nrog cov khoom siv cav tau pom zoo nrog kev ceev faj.
Cov lus qhia tshwj xeeb
Raws li kev saib xyuas nruj ntawm cov kws tshaj lij, tus neeg mob yuav tsum pauv mus rau lwm lub tshuaj insulin. Koob tshuaj yuav tau coj mus pauv thaum hloov chaw tsim tshuaj paus, hom tshuaj, qauv ntau lawm, thiab lwm yam.
Siv rau lub sijhawm qub
Qhov tshuaj insulin no tuaj yeem kho rau cov neeg laus. Kev pom zoo tseem ceeb rau pab pawg ntawm cov neeg mob no - noj tshuaj uas kws kho mob yuav tsum tau ua raws cai txhawm rau txhawm rau txhawm rau txhawm rau txo kev mob ntshav siab ntshav qab zib. Tus mob no yog txaus ntshai thaum muaj hnub nyoog laus. Kev ua rau lub plawv tsis tuaj yeem tuaj yeem ua rau muaj kev kub ntxhov, spasm ntawm cov hlab ntsha txoj hlab ntshav thiab myocardial infarction, ploj ntawm lub zeem muag.
Txiag tej menyuam
Cov tshuaj Humalogue tuaj yeem kho rau menyuam yaus yog tias nws muaj ntshav qab zib.
Siv thaum cev xeeb tub thiab lactation
Thaum cev xeeb tub thiab lactation, Siv tau Humalog. Cov kws kho mob tshwj xeeb uas tau muab cov tshuaj no rau lawv cov neeg mob tsis qhia tawm cov kev tsis pom zoo. Cov kev tshawb fawb pom tau tias cov kab mob sib piv ntawm tib neeg cov kua dej:
- tsis hla tus txiv neej;
- tsis ua rau kev xeeb tub ua tsis zoo;
- tsis ua rau hnyav nce hauv cov menyuam mos.
Cov tshuaj Humalogue tuaj yeem kho rau menyuam yaus yog tias nws muaj ntshav qab zib.
Thaum cev xeeb tub, nws yog ib qho tseem ceeb tsuas yog ua raws li cov lus qhia ntawm kws kho mob, saib xyuas qhov ntau npaum li cas. Hauv thawj 3 lub hlis, xav tau insulin tsawg. Pib txij li 4 hlis, nws nce, thiab thaum yug menyuam thiab tom qab ntawd nws tuaj yeem txo tsawg. Thaum lub sijhawm pub niam mis, qhov tsim nyog yuav tau raug kho thiab / lossis kev noj zaub mov raug noj.
Daim ntawv thov rau lub raum khiav tsis zoo
Nrog kev cuam tshuam ntawm cov plab hnyuv siab raum, cov kev xav tau cov tshuaj hormone tuaj yeem txo qis.
Siv rau lub siab ua haujlwm tsis zoo
Nrog lub siab ua haujlwm tsis zoo, kev txo qis hauv lub cev xav tau cov tshuaj insulin yog ua tau.
Lyspro insulin overdose
Nrog rau kev siv tsis tsim nyog ntawm cov tshuaj, ib qho kev siv ntau tshaj yog qhov muaj feem ntau. Hauv cov xwm txheej no, cov tsos mob ntawm cov qog ntshav qab zib tshwm sim:
- nkees;
- tawm hws ntau dhau;
- nce kev qab los noj mov;
- nce lub plawv dhia;
- mob taub hau;
- kev pw tsaug zog;
- Kiv taub hau
- pom kev tsis zoo;
- ntuav
- tsis meej pem;
- lub cev muaj zog tsis zoo, lub cev muaj zog txav los nrawm ntawm lub pob tw lossis nqua.
Thaum cev xeeb tub, Humalog tuaj yeem siv tau, vim tias cov kws tshaj lij tsis qhia txog cov kev tsis haum xeeb.
Hypoglycemia xav kom tshem tawm. Hauv qee qhov mob me, koj yuav tsum noj qabzib lossis noj qee yam khoom muaj suab thaj. Hauv cov xwm txheej hnyav me ntsis thiab nrog coma, kev pabcuam ntawm cov kws tshwj xeeb tau xav tau. Cov kws kho mob nrog cov neeg mob uas cov tsos mob ntawm lub qog ntshav qab zib txhaj glucagon (rau hauv cov leeg los yog hauv qab daim tawv nqaij) los yog cov kua nplaum (mus rau hauv cov leeg ntshav). Tom qab cov kev kho kom zoo li qub, nws yuav tsum noj cov zaub mov uas muaj cov khoom noj carbohydrates ntau.
Kev cuam tshuam nrog lwm yam tshuaj
Nrog kev tswj hwm tib lub sijhawm ntawm cov tshuaj insulin thiab tshuaj noj hauv qhov ncauj, glucocorticosteroids, tricyclic antidepressants, thiazide diuretics thiab qee yam tshuaj ntxiv, cov nyhuv hypoglycemic yuav poob qis. Tetracyclines, sulfanilamides, angiotensin hloov enzyme inhibitors, thiab lwm yam ua rau kev nce hauv pharmacological kev txiav txim siab.
Nws yog txwv tsis pub tov cov tshuaj insulin no thiab cov tshuaj uas muaj cov tsiaj insulin.
Cawv tau zoo
Tsis txhob haus dej caw muaj cawv thaum ua kev kho mob ntshav qab zib tsis pom zoo. Nrog kev sib xyaw ua ke nrog cawv nrog insulin, cov nyhuv hypoglycemic yog kho kom zoo.
Lwm pab pawg ntawm ultrashort insulins yog ntxiv los ntawm insulin aspart.
Analogs
Cov pab pawg insulin ua luv luv suav nrog tsis yog Humalog xwb, tab sis kuj siv tshuaj tiv thaiv nws tus kheej - Humalog Mix 25 thiab Humalog Mix 50. Cov tshuaj no muaj nyob hauv daim ntawv ntawm kev ncua rau kev tswj hwm hauv qab daim tawv.
Lwm pab pawg ntawm ultrashort insulins yog ntxiv los ntawm insulin aspart (tshuaj: NovoRapid Flexpen, NovoRapid Penfill) thiab insulin glulizin (tshuaj: Apidra, Apidra SoloStar).
Tseem muaj cov insulins ntawm lub sijhawm sib txawv ntawm cov kev ua:
- Luv luv. Cov tshuaj los ntawm pawg no: Rinsulin R, Humulin Tsis tu ncua, thiab lwm yam.
- Ob-theem (insulin biphasic - "bifazik"). Kev Npaj: Humodar K25-100, NovoMix 50, Flexpen, NovoMix 30, Penfill, thiab lwm yam.
- Lub sijhawm nruab nrab. Cov pab pawg suav nrog Biosulin N, thiab lwm yam.
- Ntev ntev. Qee yam tshuaj: Lantus, Levemir Penfill.
- Lub sijhawm ua haujlwm ntev. Pab pawg no muaj cov tshuaj ntawm cov tshuaj nruab nrab thiab ntev.
Cov ntsiab lus ntawm lub tsev muag tshuaj tawm
Kuv tuaj yeem yuav yam tsis tas yuav tshuaj
Cov tshuaj yuav muag hauv cov khw muag tshuaj nrog cov tshuaj uas tau sau tseg.
Lyspro insulin nqi
Cov ntim ntawm Humalog nrog ib tug xwj xaum xaum raug nqi kwv yees 1690 rubles. Tus kwv yees tus nqi ntawm ib pob nrog 5 cartridges yog 1770 rubles.
Cia rau cov neeg mob rau cov tshuaj
Cov tshuaj uas tseem tsis tau sau tawm yuav tsum tau muab cia rau hauv tub yees ntawm qhov kub uas tsis poob qis dua 2 ° C (kev daws yuav tsum tsis yog khov).
Cov tshuaj siv txhua hnub yuav tsum khaws cia hauv chav sov (tsis siab tshaj 30 ° C). Nws yuav tsum tso kom deb ntawm lub hnub thiab khoom siv cua sov. Lub sijhawm tso cia yuav tsum tsis pub ntau tshaj 28 hnub.
Cov tshuaj uas tseem tsis tau sau tawm yuav tsum tau muab cia rau hauv lub tub yees ntawm qhov kub uas tsis poob qis dua 2 ° C (kev daws yuav tsum tsis khov).
Hnub tas sij hawm
Yog tias cov tshuaj tsis tau qhib, tom qab ntawd nws tuaj yeem khaws cia li 3 xyoos txij li hnub tsim khoom.
Chaw tsim tshuaj paus
Lub chaw tsim cov tshuaj insulin nyob rau hauv lub npe ua lag luam Humalog yog lub tuam txhab Fabkis Lilly Fabkis.
Lyspro insulin tshuaj xyuas
Stanislav, hnub nyoog 55 xyoos, Tyumen: “Tau kwv yees li 10 xyoo dhau los kuv tau kuaj mob ntshav qab zib. Tshuaj tua kab mob tau pib thaum pib kho mob. Tsis ntev los no, tus kws kho mob tshwj xeeb pom zoo kom hloov mus rau Humalog tov rau kev tswj hwm subcutaneous, vim tias cov ntsiav tshuaj tsis ua rau muaj qhov xav tau. Kuv tau yuav cov tshuaj ntawm lub tsev muag tshuaj thiab tau pib txhaj nws 3 zaug ib hnub ua ntej noj mov. Kuv lub siab zoo dua li lub sijhawm thaum cov ntsiav tshuaj tsis pab. "
Elena, hnub nyoog 52 xyoo, Novosibirsk: "Kuv muaj ntshav qab zib mellitus. Txhawm rau tswj cov ntshav qabzib ib txwm, Kuv txhaj kuv tus kheej nrog insulin. Kuv nquag mus yuav cov tshuaj Humalog hauv qhov cwj mem nrog cov ntawv sau. Kuv yuav them tus nqi siab rau qhov tsis zoo. "
Khabarovsk Anastasia, hnub nyoog 54 xyoos: “Cov tshuaj yuav pab tau zoo thaum siv raug. Kuv tsis tau ua raws li tus kws kho mob pom zoo, yog li kuv feem ntau muaj cov kev mob tshwm sim. Mob khaub thuas. Ntshav qab zib mellitus yog ib yam kab mob uas yuav tsum muaj tus txheej txheem tsim nyog.
